Molecular networking-based mass spectral identification of Brucea javanica (L.) Merr. metabolites and their selective binding affinities for dengue virus enzymes
This study aims to simultaneously identify chemical classes and metabolites within B. javanica using molecular networking (MN), by Global Natural Product Social (GNPS), and SIRIUS in silico annotation. Liquid chromatography-mass spectrometry (LC-MS2)-based MN explores chemical diversity across four plant parts (leaves, roots, fruits, and stem bark), revealing diverse metabolites such as tryptophan-derived alkaloids, terpenoids, and octadecadenoids. Simultaneous LC-MS2 and MN analyses reveal a discriminative capacity for individual plant components, with roots accumulating tryptophan alkaloids, fruits concentrating quassino...
Source: Fitoterapia - April 11, 2024 Category: Biochemistry Authors: Nor Syaidatul Akmal Mohd Yousof Adlin Afzan Murizal Zainol Syahrul Imran Abu Bakar Mohd Ridzuan Mohd Abd Razak Nur Hana Md Jelas Nor Nadirah Abdullah Geoffrey A Cordell Nor Hadiani Ismail Source Type: research
Perceptions of dengue risk and acceptability of a dengue vaccine in residents of Puerto Rico
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 11, 2024 Category: Allergy & Immunology Authors: Coral Rosado-SantiagoCarmen L. P érez-GuerraNicole M. Vélez-AgostoClaudia Colón-BurgosKarla M. Marrero-SantosSusanna K. PartridgeAmy E. LockwoodCathy YoungSteve H. WatermanGabriela Paz-BaileyIris Cardona-GerenaAngel RiveraLaura E. AdamsJoshua M. Wonga Source Type: research
A systematic review on malaria and dengue vaccines for the effective management of these mosquito borne diseases: Improving public health
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 11, 2024 Category: Allergy & Immunology Authors: Hind M. Al-OsaimiMohammed KananLujain MarghlaniBadria Al-RowailiReem AlbalawiAbrar SaadSaba AlasmariKhaled AlthobaitiZainab AlhulailiAbeer AlanziRawan AlqarniRazan AlsofiyaniReem Shrwania Department of Pharmacy Services Administration, King Fahad Medical Source Type: research
Epidemiological investigation of dengue fever outbreak and its socioeconomic determinants in Banadir region, Somalia
Dengue has become an alarming global problem and is endemic in many countries, particularly in tropical and subtropical countries. The aim of this study was to investigate dengue fever outbreak in Banadir Regi... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - April 11, 2024 Category: Infectious Diseases Authors: Mohamed Abdelrahman Mohamed, Nuralein Yusuf Hassan, Marian Muse Osman, Saido Gedi, Bisma Abdullahi Ali Maalin, Kasim Mahdi Sultan, Bashiru Garba, Ali Abdirahman Osman, Abdinasir Yusuf Osman and Abdifatah Diriye Ahmed Tags: Research Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
Wolbachia-carrying Aedes mosquitoes for preventing dengue infection
CONCLUSIONS: The included trial demonstrates the potential significant impact of wMel-Wolbachia-carrying Ae aegypti mosquitoes on preventing dengue infection in an endemic setting, and supports evidence reported in non-randomized and uncontrolled studies. Further trials across a greater diversity of settings are required to confirm whether these findings apply to other locations and country settings, and greater reporting of acceptability and cost are important.PMID:38597256 | PMC:PMC11005084 | DOI:10.1002/14651858.CD015636.pub2 (Source: Cochrane Database of Systematic Reviews)
Source: Cochrane Database of Systematic Reviews - April 10, 2024 Category: General Medicine Authors: Tilly Fox Yanina Sguassero Marty Chaplin Winsley Rose Dyna Doum Ingrid Arevalo-Rodriguez Gemma Villanueva Source Type: research
Digital Transformation in the Control of Neglected Tropical Diseases: A Scoping Review
AbstractPurpose of ReviewThere is an increasing interest in the role of digital health in the healthcare industry, focusing on enhancing patient care through technologies such as electronic health records (EHRs), mobile health applications, telemedicine, and other advancements. The purpose of this review is to highlight the enormous potential of digital transformation tools in managing and mitigating neglected tropical diseases (NTDs), which affect millions of people worldwide, particularly in the Global South. To meet this purpose, we conducted a scoping review of existing literature and investigated the specific applicat...
Source: Current Tropical Medicine Reports - April 10, 2024 Category: Tropical Medicine Source Type: research
Diagnostic accuracy of DPP Fever Panel II Asia tests for tropical fever diagnosis
Conclusions/SignificanceThese results demonstrate that the diagnostic accuracy of the DPP Fever Panel II is comparable to that of commonly used RDTs. The optimal cut-off would depend on the use of the test and the desired sensitivity and specificity. Further studies are required to authenticate the use of these cut-offs in other endemic regions. This multiplex RDT offers diagnostic benefits in areas with limited access to healthcare and has the potential to improve field testing capacities. This could improve tropical fever management and reduce the public health burden in endemic low-resource areas. (Source: PLoS Neglected Tropical Diseases)
Source: PLoS Neglected Tropical Diseases - April 10, 2024 Category: Tropical Medicine Authors: Sandhya Dhawan Source Type: research
Point of care devices for detection of Covid-19, malaria and dengue infections: A review
Bioelectrochemistry. 2024 Apr 5;158:108704. doi: 10.1016/j.bioelechem.2024.108704. Online ahead of print.ABSTRACTNeed for affordable, rapid and user-friendly point of care (POC) devices are increasing exponentially for strengthening the health care system in primary care as well as for self- monitoring in routine analysis. In addition to routine analysis of glucose, Covid-19 type fast spreading, infectious diseases have created further push for exploring rapid, cost-effective and self-monitoring diagnostic devices. Successful implementation of self-monitoring devices for Covid -19 has been realized. However, not much succe...
Source: Bioelectrochemistry - April 9, 2024 Category: Biochemistry Authors: Susmita Baruah C A Betty Source Type: research
The 2023 Dengue Outbreak in Bangladesh: Exploring the Epidemiology in Hospitalized Patients
We report that a substantial number of patients developed severe dengue during the epidemic in 2023, and provide detailed clinical-epidemiological profiles of the patients, offering valuable insight into management of dengue cases.PMID:38593789 | DOI:10.4269/ajtmh.23-0806 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Urby Saraf Anika Muna Islam Fatema E Nur Mou Mrinal Saha Aparna Deb Rubaiya Rahman Tui Joarder Rakeen Manzoor Afroza Jesmin Ayesha Martuja Jannatul Fardous Mohiuddin Sharif Md Abdur Rafi Mohammad Jahid Hasan Source Type: research
The 2023 Dengue Outbreak in Bangladesh: Exploring the Epidemiology in Hospitalized Patients
We report that a substantial number of patients developed severe dengue during the epidemic in 2023, and provide detailed clinical-epidemiological profiles of the patients, offering valuable insight into management of dengue cases.PMID:38593789 | DOI:10.4269/ajtmh.23-0806 (Source: Am J Trop Med Hyg)
Source: Am J Trop Med Hyg - April 9, 2024 Category: Infectious Diseases Authors: Urby Saraf Anika Muna Islam Fatema E Nur Mou Mrinal Saha Aparna Deb Rubaiya Rahman Tui Joarder Rakeen Manzoor Afroza Jesmin Ayesha Martuja Jannatul Fardous Mohiuddin Sharif Md Abdur Rafi Mohammad Jahid Hasan Source Type: research
Point of care devices for detection of Covid-19, malaria and dengue infections: A review
Bioelectrochemistry. 2024 Apr 5;158:108704. doi: 10.1016/j.bioelechem.2024.108704. Online ahead of print.ABSTRACTNeed for affordable, rapid and user-friendly point of care (POC) devices are increasing exponentially for strengthening the health care system in primary care as well as for self- monitoring in routine analysis. In addition to routine analysis of glucose, Covid-19 type fast spreading, infectious diseases have created further push for exploring rapid, cost-effective and self-monitoring diagnostic devices. Successful implementation of self-monitoring devices for Covid -19 has been realized. However, not much succe...
Source: Bioelectrochemistry - April 9, 2024 Category: Biochemistry Authors: Susmita Baruah C A Betty Source Type: research
The 2023 Dengue Outbreak in Bangladesh: Exploring the Epidemiology in Hospitalized Patients
We report that a substantial number of patients developed severe dengue during the epidemic in 2023, and provide detailed clinical-epidemiological profiles of the patients, offering valuable insight into management of dengue cases.PMID:38593789 | DOI:10.4269/ajtmh.23-0806 (Source: The American Journal of Tropical Medicine and Hygiene)
Source: The American Journal of Tropical Medicine and Hygiene - April 9, 2024 Category: Tropical Medicine Authors: Urby Saraf Anika Muna Islam Fatema E Nur Mou Mrinal Saha Aparna Deb Rubaiya Rahman Tui Joarder Rakeen Manzoor Afroza Jesmin Ayesha Martuja Jannatul Fardous Mohiuddin Sharif Md Abdur Rafi Mohammad Jahid Hasan Source Type: research
