Silver Coordination Polymers Driven by Adamantoid Blocks for Advanced Antiviral and Antibacterial Biomaterials
This study describes the assembly and full characterization of two new bioactive silver(I) coordination polymers (CPs) formulated as [Ag(aca)(μ-PTA)]n·5nH2O (1) and [Ag2(μ-ada)(μ3-PTA)2]n·4nH2O (2). These products were generated by exploiting a heteroleptic approach based on the use of two different adamantoid building blocks, namely 1,3,5-triaza-7-phosphaadamantane (PTA) and 1-adamantanecarboxylic (Haca) or 1,3-adamantanedicarboxylic (H2ada) acids, resulting in the assembly of 1D (1) and 3D (2). Antiviral, antibacterial, and antifungal properties of the obtained compounds were investigated in detail, followed by thei...
Source: Herpes - March 8, 2024 Category: Infectious Diseases Authors: Sabina W Jaros Magdalena Florek Barbara Ba żanów Jaros ław Panek Agnieszka Krogul-Sobczak M Concei ção Oliveira Jaros ław Król Urszula Śliwińska-Hill Dmytro S Nesterov Alexander M Kirillov Piotr Smole ński Source Type: research
Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis
CONCLUSIONS: Presented OTG model constitutes a simple and convenient tool to study the interaction between bacterial and viral pathogens within the gingival tissue, including penetration, persistence and biofilm formation. It is also suitable to examine the efficiency of antimicrobial drugs.PMID:38456121 | PMC:PMC10919308 | DOI:10.1080/20002297.2023.2292382 (Source: Herpes)
Source: Herpes - March 8, 2024 Category: Infectious Diseases Authors: Anna Golda Anna Gasiorek Ewelina Dobosz Zuzanna Oruba Richard J Lamont Jan Potempa Joanna Koziel Source Type: research
Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis
CONCLUSIONS: Presented OTG model constitutes a simple and convenient tool to study the interaction between bacterial and viral pathogens within the gingival tissue, including penetration, persistence and biofilm formation. It is also suitable to examine the efficiency of antimicrobial drugs.PMID:38456121 | PMC:PMC10919308 | DOI:10.1080/20002297.2023.2292382 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - March 8, 2024 Category: Microbiology Authors: Anna Golda Anna Gasiorek Ewelina Dobosz Zuzanna Oruba Richard J Lamont Jan Potempa Joanna Koziel Source Type: research
Silver Coordination Polymers Driven by Adamantoid Blocks for Advanced Antiviral and Antibacterial Biomaterials
This study describes the assembly and full characterization of two new bioactive silver(I) coordination polymers (CPs) formulated as [Ag(aca)(μ-PTA)]n·5nH2O (1) and [Ag2(μ-ada)(μ3-PTA)2]n·4nH2O (2). These products were generated by exploiting a heteroleptic approach based on the use of two different adamantoid building blocks, namely 1,3,5-triaza-7-phosphaadamantane (PTA) and 1-adamantanecarboxylic (Haca) or 1,3-adamantanedicarboxylic (H2ada) acids, resulting in the assembly of 1D (1) and 3D (2). Antiviral, antibacterial, and antifungal properties of the obtained compounds were investigated in detail, followed by thei...
Source: Herpes - March 8, 2024 Category: Infectious Diseases Authors: Sabina W Jaros Magdalena Florek Barbara Ba żanów Jaros ław Panek Agnieszka Krogul-Sobczak M Concei ção Oliveira Jaros ław Król Urszula Śliwińska-Hill Dmytro S Nesterov Alexander M Kirillov Piotr Smole ński Source Type: research
Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis
CONCLUSIONS: Presented OTG model constitutes a simple and convenient tool to study the interaction between bacterial and viral pathogens within the gingival tissue, including penetration, persistence and biofilm formation. It is also suitable to examine the efficiency of antimicrobial drugs.PMID:38456121 | PMC:PMC10919308 | DOI:10.1080/20002297.2023.2292382 (Source: Herpes)
Source: Herpes - March 8, 2024 Category: Infectious Diseases Authors: Anna Golda Anna Gasiorek Ewelina Dobosz Zuzanna Oruba Richard J Lamont Jan Potempa Joanna Koziel Source Type: research
Neonatal herpes simplex virus encephalitis with intracranial bleeding in a newborn baby with concurrent rhesus incompatibility
We report a baby with neonatal herpes simplex virus (HSV) encephalitis concurrent with Rrhesus (Rh) incompatibility. He was delivered by a Ggravida 2 mother with a history of miscarriage in her previous pregnancy at a gestation age of 4 months. She had Bblood group 0 and Rrhesus negative. The baby was noticed to have jaundice on day one1 of life accompanied by generalised petechiae on the face and upper chest. A full blood picture revealed severe anaemia and severe thrombocytopaenia and HSV 1/2 IgM was positive. MRI of the brain showed multiple extensive haemorrhagic lesions on the frontal-temporal regions.PMID:38458763 | ...
Source: Herpes - March 8, 2024 Category: Infectious Diseases Authors: Pascal Clemence Haika Mariki Martha Mkony Karim Premji Manji Source Type: research
Four new resin glycosides from Ipomoea muricata seeds: muricatins XIV-XVII
J Nat Med. 2024 Mar 8. doi: 10.1007/s11418-024-01787-1. Online ahead of print.ABSTRACTIpomoea muricata (L.) Jacq. seeds (Convolvulaceae) are used as a traditional laxative and carminative medicine. Muricatins XIV (1), XV (2), XVI (3), and XVII (4), were isolated from I. muricata seeds as four new resin glycosides, along with seven known compounds, three of which were isolated for the first time as natural products; their structures were determined using MS and NMR spectroscopy. Compounds 1-4 are macrolactones (jalapins); the sugar moieties of 1, 2, and 4 are partially acylated with 2S-methylbutyric acid, while that of 3 is...
Source: Herpes - March 8, 2024 Category: Infectious Diseases Authors: Masateru Ono Daiki Tenmaya Maki Tarumi Syouri Satou Kotone Tsuji Hirotaka Nishikawa Shin Yasuda Hiroyuki Miyashita Jian-Rong Zhou Kazumi Yokomizo Hitoshi Yoshimitsu Ryota Tsuchihashi Masafumi Okawa Junei Kinjo Source Type: research
Organotypic model of the gingiva for studying bacterial and viral pathogens implicated in periodontitis
CONCLUSIONS: Presented OTG model constitutes a simple and convenient tool to study the interaction between bacterial and viral pathogens within the gingival tissue, including penetration, persistence and biofilm formation. It is also suitable to examine the efficiency of antimicrobial drugs.PMID:38456121 | PMC:PMC10919308 | DOI:10.1080/20002297.2023.2292382 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - March 8, 2024 Category: Microbiology Authors: Anna Golda Anna Gasiorek Ewelina Dobosz Zuzanna Oruba Richard J Lamont Jan Potempa Joanna Koziel Source Type: research
