Therapeutic advances in atrial fibrillation based on animal models
J Zhejiang Univ Sci B. 2024 Feb 15;25(2):135-152. doi: 10.1631/jzus.B2300285.ABSTRACTAtrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age. Despite the high frequency of AF in clinical practice, its etiology and management remain elusive. To develop effective treatment strategies, it is imperative to comprehend the underlying mechanisms of AF; therefore, the establishment of animal models of AF is vital to explore its pathogenesis. While spontaneous AF is rare in most animal species, several large animal models, particularly those of p...
Source: J Zhejiang Univ Sci ... - February 2, 2024 Category: Science Authors: Qian Gong Xuan LE Pengcheng Yu Lenan Zhuang Source Type: research
Therapeutic advances in atrial fibrillation based on animal models
J Zhejiang Univ Sci B. 2024 Feb 15;25(2):135-152. doi: 10.1631/jzus.B2300285.ABSTRACTAtrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age. Despite the high frequency of AF in clinical practice, its etiology and management remain elusive. To develop effective treatment strategies, it is imperative to comprehend the underlying mechanisms of AF; therefore, the establishment of animal models of AF is vital to explore its pathogenesis. While spontaneous AF is rare in most animal species, several large animal models, particularly those of p...
Source: J Zhejiang Univ Sci ... - February 2, 2024 Category: Science Authors: Qian Gong Xuan LE Pengcheng Yu Lenan Zhuang Source Type: research
Therapeutic advances in atrial fibrillation based on animal models
J Zhejiang Univ Sci B. 2024 Feb 15;25(2):135-152. doi: 10.1631/jzus.B2300285.ABSTRACTAtrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age. Despite the high frequency of AF in clinical practice, its etiology and management remain elusive. To develop effective treatment strategies, it is imperative to comprehend the underlying mechanisms of AF; therefore, the establishment of animal models of AF is vital to explore its pathogenesis. While spontaneous AF is rare in most animal species, several large animal models, particularly those of p...
Source: J Zhejiang Univ Sci ... - February 2, 2024 Category: Science Authors: Qian Gong Xuan LE Pengcheng Yu Lenan Zhuang Source Type: research
Therapeutic advances in atrial fibrillation based on animal models
J Zhejiang Univ Sci B. 2024 Feb 15;25(2):135-152. doi: 10.1631/jzus.B2300285.ABSTRACTAtrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age. Despite the high frequency of AF in clinical practice, its etiology and management remain elusive. To develop effective treatment strategies, it is imperative to comprehend the underlying mechanisms of AF; therefore, the establishment of animal models of AF is vital to explore its pathogenesis. While spontaneous AF is rare in most animal species, several large animal models, particularly those of p...
Source: J Zhejiang Univ Sci ... - February 2, 2024 Category: Science Authors: Qian Gong Xuan LE Pengcheng Yu Lenan Zhuang Source Type: research
Therapeutic advances in atrial fibrillation based on animal models
AbstractAtrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia among humans, with its incidence increasing significantly with age. Despite the high frequency of AF in clinical practice, its etiology and management remain elusive. To develop effective treatment strategies, it is imperative to comprehend the underlying mechanisms of AF; therefore, the establishment of animal models of AF is vital to explore its pathogenesis. While spontaneous AF is rare in most animal species, several large animal models, particularly those of pigs, dogs, and horses, have proven as invaluable in recent years in advancing...
Source: Journal of Zhejiang University. Science. B. - February 1, 2024 Category: Universities & Medical Training Source Type: research
Bipolar catheter ablation with dedicated radiofrequency system for highly refractory ventricular arrhythmia —Does the rate of success depend on arrhythmia origin?
ConclusionsB-RFA is a promising method of catheter ablation for refractory cardiac arrhythmias. A higher success rate was observed in ablation for difficult ventricular arrhythmias originating from interventricular septal region than LV summit. (Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - January 31, 2024 Category: Cardiology Authors: Piotr Gardziejczyk,
Roman Piotrowski,
Tomasz Kry ński,
Agnieszka Sikorska,
Piotr Kułakowski,
Jakub Baran Tags: ORIGINAL ARTICLE Source Type: research
Top Stories: Mitochondrial origin of inherited cardiac arrhythmias
Mitochondria control cardiac function by regulating adenosine triphosphate synthesis, reactive oxygen species (ROS) generation, intracellular calcium (Ca2+), and the cellular redox state. Yet, their role in the pathophysiology of arrhythmias remains massively underappreciated. In this Top Stories article, we shed light on this issue by focusing on recent advances in our understanding of mechanisms by which mitochondria act as central mediators of inherited arrhythmic disorders. (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Fadi G. Akar, Christoph Maack Tags: Top Stories Source Type: research
CAST: A study that rocked the cardiology world and became the poster child for evidence-based medicine
The main result of the CAST (Cardiac Arrhythmia Suppression Trial), shown in Figure 1,1 was completely unexpected: The suppression of ventricular ectopy with antiarrhythmic drugs (AADs) was associated with an increased incidence of lethal ventricular arrhythmias in patients with post–myocardial infarction (post-MI) at high risk of sudden cardiac death (SCD). (Source: Heart Rhythm)
Source: Heart Rhythm - January 29, 2024 Category: Cardiology Authors: Debra Echt Tags: Iconic Figure Source Type: research
The Cost of Atrial Fibrillation: A Systematic Review
Atrial fibrillation (AF) is the most common cardiac arrhythmia, with an increasing incidence and prevalence due to progressively ageing populations. Costs related to AF are both direct and indirect. This systematic review aims to identify the main cost drivers of the illness, assess the potential economic impact resulting from changes in care strategies and propose interventions where they are most needed. (Source: Value in Health)
Source: Value in Health - January 29, 2024 Category: International Medicine & Public Health Authors: Alessandra Buja, Vincenzo Rebba, Laura Montecchio, Giulia Renzo, Vincenzo Baldo, Silvia Cocchio, Nicola Ferri, Federico Migliore, Alessandro Zorzi, Brendan Collins, Che ïma Amrouch, Delphine De Smedt, Christodoulos Kypridemos, Mirko Petrovic, Martin O’ Tags: Systematic Literature Review Source Type: research
The safety and efficacy of nonvitamin K antagonist oral anticoagulants in morbidly obese patients with atrial fibrillation: a meta-analysis
Atrial fibrillation (AF) is the most frequently observed cardiac arrhythmia in clinical settings. Obesity can influence the efficacy of the treatment administered, which requires a larger dose and more time to... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - January 26, 2024 Category: Cardiology Authors: Sohil Elfar, Somaya Abdulbaset Mahmoud, Samar Hamdi, Aya Ahmed Emad, Mohamed Abd-ElGawad and Nouran A. Taha Tags: Research Source Type: research
Identifying factors that worsen in-hospital outcomes in patients with ventricular tachycardia (vt) and inflammatory bowel disease (ibd).
IBD is a proinflammatory state that can have numerous complications involving all systems of the body. There is a known association with cardiovascular disease. However, there are limited studies that have examined the impact of cardiac arrhythmias such as VT on patients with IBD (Crohn ’s Disease and Ulcerative Colitis). The aim of this study was to evaluate the economic burden and various hospital outcomes associated with patients with IBD with and without VT. (Source: Gastroenterology)
Source: Gastroenterology - January 25, 2024 Category: Gastroenterology Authors: Jason John, Akshay Kapoor, Neethi Dasu, Yaser Khalid, Brian Blair, Lucy Joo Source Type: research
A Case of a Presurgical Abnormal Rhythm
Am J Nurs. 2024 Feb 1;124(2):58-60. doi: 10.1097/01.NAJ.0001006724.55411.8f.ABSTRACTEditor's note: This is the next installment in a series on electrocardiogram (ECG) interpretation. Nurses in all settings should know the basics, as medications and physiological changes can cause cardiac arrhythmias. Each article will start with a brief case scenario and an ECG strip and then take you step by step through analyzing the heart rhythm.PMID:38270428 | DOI:10.1097/01.NAJ.0001006724.55411.8f (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - January 25, 2024 Category: Nursing Authors: Nicole Kupchik Courtney Wallace Source Type: research
A Case of a Presurgical Abnormal Rhythm
Am J Nurs. 2024 Feb 1;124(2):58-60. doi: 10.1097/01.NAJ.0001006724.55411.8f.ABSTRACTEditor's note: This is the next installment in a series on electrocardiogram (ECG) interpretation. Nurses in all settings should know the basics, as medications and physiological changes can cause cardiac arrhythmias. Each article will start with a brief case scenario and an ECG strip and then take you step by step through analyzing the heart rhythm.PMID:38270428 | DOI:10.1097/01.NAJ.0001006724.55411.8f (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - January 25, 2024 Category: Nursing Authors: Nicole Kupchik Courtney Wallace Source Type: research
A Case of a Presurgical Abnormal Rhythm
Am J Nurs. 2024 Feb 1;124(2):58-60. doi: 10.1097/01.NAJ.0001006724.55411.8f.ABSTRACTEditor's note: This is the next installment in a series on electrocardiogram (ECG) interpretation. Nurses in all settings should know the basics, as medications and physiological changes can cause cardiac arrhythmias. Each article will start with a brief case scenario and an ECG strip and then take you step by step through analyzing the heart rhythm.PMID:38270428 | DOI:10.1097/01.NAJ.0001006724.55411.8f (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - January 25, 2024 Category: Nursing Authors: Nicole Kupchik Courtney Wallace Source Type: research
A Case of a Presurgical Abnormal Rhythm
Am J Nurs. 2024 Feb 1;124(2):58-60. doi: 10.1097/01.NAJ.0001006724.55411.8f.ABSTRACTEditor's note: This is the next installment in a series on electrocardiogram (ECG) interpretation. Nurses in all settings should know the basics, as medications and physiological changes can cause cardiac arrhythmias. Each article will start with a brief case scenario and an ECG strip and then take you step by step through analyzing the heart rhythm.PMID:38270428 | DOI:10.1097/01.NAJ.0001006724.55411.8f (Source: The American Journal of Nursing)
Source: The American Journal of Nursing - January 25, 2024 Category: Nursing Authors: Nicole Kupchik Courtney Wallace Source Type: research
