CAST: A study that rocked the cardiology world and became the poster child for evidence-based medicine

The main result of the CAST (Cardiac Arrhythmia Suppression Trial), shown in Figure  1,1 was completely unexpected: The suppression of ventricular ectopy with antiarrhythmic drugs (AADs) was associated with an increased incidence of lethal ventricular arrhythmias in patients with post–myocardial infarction (post-MI) at high risk of sudden cardiac death (SCD).
Source: Heart Rhythm - Category: Cardiology Authors: Tags: Iconic Figure Source Type: research