The Significance of Widely Split P Waves The Significance of Widely Split P Waves
This case highlights the need to be aware that the presence of widely split P waves on an ECG may proceed to more serious cardiac arrhythmias during an anesthetic procedure.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 23, 2022 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

New IMBRUVICA ® (ibrutinib) Data in Fixed-Duration Combination Regimen Presented at EHA 2022 Shows Deep, Durable Response at Three Years in Untreated Chronic Lymphocytic Leukemia
June 10, 2022 (VIENNA) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new and updated results from the Phase 2 CAPTIVATE study evaluating IMBRUVICA® (ibrutinib) in combination with venetoclax (I+V) as a potential fixed-duration (FD) treatment in adult patients with previously untreated chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). Updated data from the FD cohort with three years of follow-up shows that I+V continues to demonstrate deep and durable responses and clinically meaningful progression-free survival (PFS) and overall survival (OS) in the first-line tre...
Source: Johnson and Johnson - June 10, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Phase 3 SHINE Results Show IMBRUVICA ® (ibrutinib)-Based Combination Regimen Significantly Reduced the Risk of Disease Progression or Death in Older Patients with Newly Diagnosed Mantle Cell Lymphoma
This study is one of the largest clinical trials ever conducted in first-line MCL and the first for a Bruton’s tyrosine kinase inhibitor (BTKi).[1] The data are being presented in an oral session and featured in a press briefing during the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, and were published in The New England Journal of Medicine today. The data will also be presented as an oral presentation at the 2022 European Hematology Association (EHA) Annual Congress. MCL is a type of aggressive, rare non-Hodgkin lymphoma (NHL) that is incurable and difficult to treat.[2] It commonly affects people o...
Source: Johnson and Johnson - June 3, 2022 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen to Highlight Science, Innovation and Advances in Robust Oncology Portfolio and Pipeline Through More Than 60 Data Presentations at ASCO and EHA
RARITAN, N.J., May 31, 2022 — The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that new research and data from its robust oncology portfolio and pipeline of investigational therapies will be presented at the 2022 American Society of Clinical Oncology (ASCO) Annual Meeting, taking place June 3-7 in Chicago, and the European Hematology Association (EHA) 2022 Congress taking place in Vienna, Austria, June 9-12. More than 60 presentations from company-sponsored studies across the two congresses, including 14 oral presentations, will feature new data and updates for both approved and investigation...
Source: Johnson and Johnson - May 31, 2022 Category: Pharmaceuticals Source Type: news

Single-substance trazodone exposures reported to US poison centers from 2000 to 2019 - Husak N, Leonard JB, Seung H, Klein-Schwartz W.
BACKGROUND: Individual case reports describe trazodone overdose resulting in QTc prolongation and cardiac arrhythmias. The clinical effects and outcomes associated with trazodone exposures on a large-scale basis are less well known. OBJECTIVE: The ... (Source: SafetyLit)
Source: SafetyLit - May 2, 2022 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Sepsis-driven atrial fibrillation and ischaemic stroke. Is there enough evidence to recommend anticoagulation?
Sepsis can lead to cardiac arrhythmias, of which the most common is atrial fibrillation (AF). Sepsis is associated with up to a six-fold higher risk of developing AF, where it occurs most commonly in the first 3 days of hospital admission. In many patients, AF detected during sepsis is the first documented episode of AF, either as an unmasking of sub-clinical AF or as a newly developed arrhythmia. In the short term, sepsis that is complicated by AF leads to longer hospital stays and an increased risk of inpatient mortality. Sepsis-driven AF can also increase an individual ' s risk of inpatient stroke by nearly 3-fold, comp...
Source: Current Awareness Service for Health (CASH) - April 13, 2022 Category: Consumer Health News Source Type: news

Cardiac Arrhythmia Should Be Considered With Nocturnal Enuresis Cardiac Arrhythmia Should Be Considered With Nocturnal Enuresis
New research suggests doctors rarely evaluate patients with nocturnal enuresis for cardiac arrhythmias as part of the diagnostic workup.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - April 12, 2022 Category: Neurology Tags: Cardiology News Source Type: news

Sepsis-driven atrial fibrillation and ischaemic stroke. Is there enough evidence to recommend anticoagulation?
Sepsis can lead to cardiac arrhythmias, of which the most common is atrial fibrillation (AF). Sepsis is associated with up to a six-fold higher risk of developing AF, where it occurs most commonly in the first 3 days of hospital admission. In many patients, AF detected during sepsis is the first documented episode of AF, either as an unmasking of sub-clinical AF or as a newly developed arrhythmia. In the short term, sepsis that is complicated by AF leads to longer hospital stays and an increased risk of inpatient mortality. Sepsis-driven AF can also increase an individual ' s risk of inpatient stroke by nearly 3-fold, comp...
Source: Current Awareness Service for Health (CASH) - April 7, 2022 Category: Consumer Health News Source Type: news

Autonomic Modulation and Cardiac Arrhythmias Autonomic Modulation and Cardiac Arrhythmias
This review explores the complex contributions of the autonomic nervous system in cardiac disease, highlighting pharmacological and experimental autonomic modulation in treatment of arrhythmias.Europace (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - December 21, 2021 Category: Surgery Tags: Cardiology Journal Article Source Type: news

New Data from Phase 3 GLOW Study Show Fixed-Duration Treatment with IMBRUVICA ® (ibrutinib) Plus Venetoclax Demonstrated Deeper and Sustained Undetectable Minimal Residual Disease Outcomes in First-Line Chronic Lymphocytic Leukemia
ATLANTA, Ga., December 11, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced new data from two studies evaluating the efficacy and safety of IMBRUVICA® (ibrutinib) plus venetoclax (I+V) as a potential fixed-duration treatment in adult patients with previously untreated chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). These data were both featured today during the American Society of Hematology (ASH) 2021 Annual Meeting. New secondary endpoint data from the Phase 3 GLOW study (NCT03462719) showed that fixed-duration treatment with I+V resulted in undetectable min...
Source: Johnson and Johnson - December 11, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Janssen to Present the Strength and Promise of its Hematologic Malignancies Portfolio and Pipeline at ASH 2021
RARITAN, N.J., November 4, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 45 company-sponsored abstracts, including 11 oral presentations, plus more than 35 investigator-initiated studies will be featured at the American Society of Hematology (ASH) Annual Meeting and Exposition. ASH is taking place at the Georgia World Congress Center in Atlanta and virtually from December 11-14, 2021.“We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline during ASH...
Source: Johnson and Johnson - November 5, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Upstate Professor Auerbach receives International CURE Epilepsy award
Auerbach ’s team will use analytical tools that are well accepted in the cardiac field, but new to the epilepsy and SUDEP (sudden unexpected death) field, to identify epilepsy patient populations at risk of cardiac arrhythmias. (Source: SUNY Upstate Medical)
Source: SUNY Upstate Medical - November 4, 2021 Category: Universities & Medical Training Tags: News Source Type: news

What is Refeeding Syndrome?
Discussion Anorexia nervosa is an eating disorder with an intense fear of being overweight (i.e. distorted body image), and self-starvation and excessive weight loss. It is more common in women (1.2%) than men (0.2%) but can be seen in both genders. Risk factors include high-intelligence, perfectionism/inflexibility, anxiety, activities where thinner body types are expected (e.g. dancer, diver, gymnast, long-distance runner, volleyball player, etc.) Other eating disorders include bulimia nervosa (i.e. cycles of binge eating and then purging), binge eating disorder (i.e. purging), orthorexia (i.e. obsessions with healthful ...
Source: PediatricEducation.org - October 25, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Texas Woman Sentenced to 6 Months in Federal Prison for Selling Deadly Weight Loss Drug to Consumers
FDA OCI, Judith Holloway, Watauga TX, DNP, 2,4-Dinitrophenol, weight loss, cataracts, dangerous, side effects, hyperthermia, tachycardia, cardiac arrhythmia, death, misbranded, yellow pigment powder, bulk purchase, eBay, hazardous, false label, (Source: Office of Criminal Investigations (OCI) Press Releases)
Source: Office of Criminal Investigations (OCI) Press Releases - October 7, 2021 Category: Medical Law Authors: DOJ Source Type: news

Landmark study finds one in two hospitalised COVID-19 patients develop a complication, NIHR
A large-scale, NIHR-supported observational study published in The Lancet has found that one in two people hospitalised with COVID-19 during the first phase of the pandemic developed at least one health complication as a result of the viral infection. The ISARIC/CO-CIN study is the most comprehensive of its kind - and the first to systematically assess a range of in-hospital complications and their associations with age, sex and ethnicity - and their outcomes for the patients. The researchers assessed more than 70,000 hospitalised adult patients in the UK hospitalised with severe COVID-19 disease between January and Augu...
Source: Current Awareness Service for Health (CASH) - July 26, 2021 Category: Consumer Health News Source Type: news