Predicting the risk of early intensive care unit admission for patients hospitalized with acute pancreatitis using supervised machine learning
CONCLUSIONS: This supervised machine learning-based model can help recognize high-risk AP hospitalizations. Clinicians may use the IAPR score to identify patients with AP at high risk of ICU admission within the first week of hospitalization.PMID:38628340 | PMC:PMC11018057 | DOI:10.1080/08998280.2024.2326371 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Hassam Ali Faisal Inayat Rubaid Dhillon Pratik Patel Arslan Afzal Christin Wilkinson Attiq Ur Rehman Muhammad Sajeel Anwar Gul Nawaz Ahtshamullah Chaudhry Junaid Rasul Awan Muhammad Sohaib Afzal Jayanta Samanta Douglas G Adler Babu P Mohan Source Type: research

Atrial fibrillation: real-life experience of a rhythm control with electrical cardioversion in a community hospital
Atrial fibrillation is the most prevalent sustained cardiac arrhythmia. Electrical cardioversion, a well-established part of the rhythm control strategy, is probably underused in community settings. Here, we d... (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - April 17, 2024 Category: Cardiology Authors: Artemiy Okhotin, Maxim Osipov, Vasilij Osipov and Anton Barchuk Tags: Research Source Type: research

Photoplethysmography based atrial fibrillation detection: a continually growing field
Objective. Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with significant health ramifications, including an elevated susceptibility to ischemic stroke, heart disease, and heightened mortality. Photoplethysmography (PPG) has emerged as a promising technology for continuous AF monitoring for its cost-effectiveness and widespread integration into wearable devices. Our team previously conducted an exhaustive review on PPG-based AF detection before June 2019. However, since then, more advanced technologies have emerged in this field. Approach. This paper offers a comprehensive review of the latest advan...
Source: Physiological Measurement - April 16, 2024 Category: Physiology Authors: Cheng Ding, Ran Xiao, Weijia Wang, Elizabeth Holdsworth and Xiao Hu Source Type: research

Impact of atrial fibrillation on 1-year outcome in patients with implantable cardioverter defibrillator or cardiac resynchronization therapy with defibrillator: results from the German DEVICE Registry
CONCLUSIONS: Our clinical data on an extended cohort of contemporary patients confirm the significant impact of AF, and its associated comorbidities, upon mortality and major adverse events after implantation of ICD/CRT.PMID:38617758 | PMC:PMC11009579 | DOI:10.21037/jtd-23-274 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Sebastian Feickert Niels Christian Ewertsen Julia K öbe Thomas Kleemann Joachim Jehle Jochen Senges Matthias Hochadel Dietrich Andresen Christoph Stellbrink Lars Eckardt Stefan Spitzer Johannes Brachmann H üseyin Ince Giuseppe D'Ancona Source Type: research

Carnitine palmitoyltransferase II (CPT II) deficiency responsible for refractory cardiac arrhythmias, acute multiorgan failure and early fatal outcome
Carnitine palmitoyltransferase II (CPT II) deficiency is a rare inborn error of mitochondrial fatty acid metabolism with autosomal recessive pattern of inheritance. Its phenotype is highly variable (neonatal, ... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - April 14, 2024 Category: Pediatrics Authors: Gregorio Serra, Vincenzo Antona, Vincenzo Insinga, Giusy Morgante, Alessia Vassallo, Simona La Placa, Ettore Piro, Sergio Salerno, Ingrid Anne Mandy Schierz, Eloisa Gitto, Mario Giuffr è and Giovanni Corsello Tags: Case report Source Type: research

Carnitine palmitoyltransferase II (CPT II) deficiency responsible for refractory cardiac arrhythmias, acute multiorgan failure and early fatal outcome
ConclusionsCPTII deficiency may be suspected in newborns showing cardiac arrhythmias, associated or not with hypertrophic cardiomyopathy, polycystic kidneys, brain malformations, hepatomegaly. Its diagnosis should be even more suspected and investigated in cases of increased plasmatic levels of creatine phosphokinase and acylcarnitines in addition to kidney, heart and liver dysfunctions, as occurred in the present patient. Accurate family history, extended metabolic screening, and multidisciplinary approach are necessary for diagnosis and adequate management of affected subjects. Next generation sequencing (NGS) techniques...
Source: Italian Journal of Pediatrics - April 14, 2024 Category: Pediatrics Source Type: research

2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation
In the last three decades, ablation of atrial fibrillation (AF) has become an evidence-based safe and efficacious treatment for managing the most common cardiac arrhythmia. In 2007, the first joint expert consensus document was issued, guiding healthcare professionals involved in catheter or surgical AF ablation. Mounting research evidence and technological advances have resulted in a rapidly changing landscape in the field of catheter and surgical AF ablation, thus stressing the need for regularly updated versions of this partnership which were issued in 2012 and 2017. Seven years after the last consensus, an updated docu...
Source: Journal of Interventional Cardiac Electrophysiology - April 13, 2024 Category: Cardiology Source Type: research

Sensors, Vol. 24, Pages 2484: Cardiac Arrhythmia Classification Using Advanced Deep Learning Techniques on Digitized ECG Datasets
an Adnan Shahid ECG classification or heartbeat classification is an extremely valuable tool in cardiology. Deep learning-based techniques for the analysis of ECG signals assist human experts in the timely diagnosis of cardiac diseases and help save precious lives. This research aims at digitizing a dataset of images of ECG records into time series signals and then applying deep learning (DL) techniques on the digitized dataset. State-of-the-art DL techniques are proposed for the classification of the ECG signals into different cardiac classes. Multiple DL models, including a convolutional neural network (CNN), a lon...
Source: Sensors - April 12, 2024 Category: Biotechnology Authors: Shoaib Sattar Rafia Mumtaz Mamoon Qadir Sadaf Mumtaz Muhammad Ajmal Khan Timo De Waele Eli De Poorter Ingrid Moerman Adnan Shahid Tags: Article Source Type: research

Digital twins for cardiac electrophysiology: state of the art and future challenges
This article provides a short overview of the history of digital twins for cardiac electrophysiology, including recent applications for the prediction of sudden cardiac death risk and the tailoring of rhythm control in atrial fibrillation. The authors highlight the current c hallenges for routine clinical application and discuss how overcoming these challenges may allow digital twins to enable a significant precision medicine-based advancement in cardiac arrhythmia management. (Source: Herzschrittmachertherapie und Elektrophysiologie)
Source: Herzschrittmachertherapie und Elektrophysiologie - April 12, 2024 Category: Cardiology Source Type: research

Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions
Circ Res. 2024 Apr 12;134(8):1029-1045. doi: 10.1161/CIRCRESAHA.123.323477. Epub 2024 Apr 11.ABSTRACTThere has been increased awareness of the linkage between environmental exposures and cardiovascular health and disease. Atrial fibrillation is the most common sustained cardiac arrhythmia, affecting millions of people worldwide and contributing to substantial morbidity and mortality. Although numerous studies have explored the role of genetic and lifestyle factors in the development and progression of atrial fibrillation, the potential impact of environmental determinants on this prevalent condition has received comparativ...
Source: Circulation Research - April 11, 2024 Category: Cardiology Authors: Sojin Youn Wass Omar Hahad Zain Asad Shuo Li Mina K Chung Emelia J Benjamin Khurram Nasir Sanjay Rajagopalan Sadeer G Al-Kindi Source Type: research

Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions
Circ Res. 2024 Apr 12;134(8):1029-1045. doi: 10.1161/CIRCRESAHA.123.323477. Epub 2024 Apr 11.ABSTRACTThere has been increased awareness of the linkage between environmental exposures and cardiovascular health and disease. Atrial fibrillation is the most common sustained cardiac arrhythmia, affecting millions of people worldwide and contributing to substantial morbidity and mortality. Although numerous studies have explored the role of genetic and lifestyle factors in the development and progression of atrial fibrillation, the potential impact of environmental determinants on this prevalent condition has received comparativ...
Source: Circulation Research - April 11, 2024 Category: Cardiology Authors: Sojin Youn Wass Omar Hahad Zain Asad Shuo Li Mina K Chung Emelia J Benjamin Khurram Nasir Sanjay Rajagopalan Sadeer G Al-Kindi Source Type: research

Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions
Circ Res. 2024 Apr 12;134(8):1029-1045. doi: 10.1161/CIRCRESAHA.123.323477. Epub 2024 Apr 11.ABSTRACTThere has been increased awareness of the linkage between environmental exposures and cardiovascular health and disease. Atrial fibrillation is the most common sustained cardiac arrhythmia, affecting millions of people worldwide and contributing to substantial morbidity and mortality. Although numerous studies have explored the role of genetic and lifestyle factors in the development and progression of atrial fibrillation, the potential impact of environmental determinants on this prevalent condition has received comparativ...
Source: Circulation Research - April 11, 2024 Category: Cardiology Authors: Sojin Youn Wass Omar Hahad Zain Asad Shuo Li Mina K Chung Emelia J Benjamin Khurram Nasir Sanjay Rajagopalan Sadeer G Al-Kindi Source Type: research

Surgical ablation for atrial fibrillation: risk factors for recurrence and long-term outcome
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Due to the insufficient efficacy of antiarrhythmic drugs and their adverse side effects, there has been considerable interest in the interventional treatment of AF, including both catheter ablation and surgical ablation. Surgical ablation or "maze procedure" is a treatment option for patients with AF undergoing concomitant or isolated cardiac surgery. (Source: Journal of Cardiothoracic and Vascular Anesthesia)
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 11, 2024 Category: Anesthesiology Authors: Jonathan Frogel, Alexander Kogan, John G Augoustides, Tamer Jamal, Nir Shimoni, Roni Postan-Koren, Viktoriia Ivanov, Avi Sabbag, Ehud Raanani, Leonid Sternik Tags: Original Article Source Type: research

Decreased connexin 40 expression of the sinoatrial node mediates ischemic stroke-induced arrhythmia in mice
CONCLUSIONS: In conclusion, decreased connexin 40 expression in the sinoatrial node contributed to the ischemic stroke-induced cardiac arrhythmia. Therefore, enhancing connexin 40 expression holds promise as a potential therapeutic approach for ischemic stroke-induced arrhythmia.PMID:38599368 | DOI:10.1016/j.expneurol.2024.114773 (Source: Experimental Neurology)
Source: Experimental Neurology - April 10, 2024 Category: Neurology Authors: Zhi-Jun Yao Yan-Pin Jiang Dan Yuan Pu Hong Meng-Jiao He Feng-Xian Li Shi-Yuan Xu Hong-Bin Lin Hong-Fei Zhang Source Type: research