Journal of Cardiovascular Electrophysiology special section: The European Cardiac Arrhythmia Society 2023 meeting
(Source: Journal of Cardiovascular Electrophysiology)
Source: Journal of Cardiovascular Electrophysiology - March 7, 2024 Category: Cardiology Authors: Bharat K. Kantharia, Bradley Knight, Samuel L évy, Riccardo Cappato Tags: EDITORIAL Source Type: research

Sensors, Vol. 24, Pages 1699: Sensor-Based Measurement Method to Support the Assessment of Robot-Assisted Radiofrequency Ablation
idegger Digital surgery technologies, such as interventional robotics and sensor systems, not only improve patient care but also aid in the development and optimization of traditional invasive treatments and methods. Atrial Fibrillation (AF) is the most common cardiac arrhythmia with critical clinical relevance today. Delayed intervention can lead to heart failure, stroke, or sudden cardiac death. Although many advances have been made in the field of radiofrequency (RF) catheter ablation (CA), it can be further developed by incorporating sensor technology to improve its efficacy and safety. Automation can be utilized t...
Source: Sensors - March 6, 2024 Category: Biotechnology Authors: Hilda Zsanett Marton P álma Emese Inczeffy Zsuzsanna Kis Attila Kardos Tam ás Haidegger Tags: Article Source Type: research

Unveiling the Hidden Stroke Threat in Patients with Atrial Fibrillation and Primary Hyperparathyroidism
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with a significant association with ischemic stroke1. Risk assessment tools, such as the CHA2DS2-VASc score, have been instrumental in helping clinicians predict stroke risk in AF patients and guide preventive anticoagulation therapy2. However, while traditional and non-traditional cardiovascular (CV) risk factors have been extensively studied, the influence of non-diabetic endocrine disorders on thrombotic risk in AF remains understudied3, 4. (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - March 5, 2024 Category: Cardiology Authors: Georges Khattar, Samer Asmar, Elie Bou Sanayeh, Praneeth Keesari, Wissam Rahi, Fouad Sakr, Michel Khoury, Michael Cinelli, Samantha Lee, Mitchell Weinberg, Marcin Kowalski, Valay Parikh Source Type: research

Cardiac arrhythmogenesis: roles of ion channels and their functional modification
Cardiac arrhythmias cause significant morbidity and mortality and pose a major public health problem. They arise from disruptions in the normally orderly propagation of cardiac electrophysiological activation and recovery through successive cardiomyocytes in the heart. They reflect abnormalities in automaticity, initiation, conduction, or recovery in cardiomyocyte excitation. The latter properties are dependent on surface membrane electrophysiological mechanisms underlying the cardiac action potential. Their disruption results from spatial or temporal instabilities and heterogeneities in the generation and propagation of c...
Source: Frontiers in Physiology - March 4, 2024 Category: Physiology Source Type: research

A new approach for heart disease detection using Motif transform-based CWT's time-frequency images with DenseNet deep transfer learning methods
CONCLUSIONS: The combined approach of MT + CWT + DenseNET yielded an impressive success rate of 99.31 %.PMID:38425179 | DOI:10.1515/bmt-2023-0580 (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - March 1, 2024 Category: Biomedical Engineering Authors: Hazret Tekin Y ılmaz Kaya Source Type: research

Reduced kinase function in two ultra-rare TNNI3K variants in families with congenital junctional ectopic tachycardia
Clin Genet. 2024 Feb 29. doi: 10.1111/cge.14504. Online ahead of print.ABSTRACTGenetic missense variants in TNNI3K, encoding troponin-I interacting kinase, have been associated with dilated cardiomyopathy (DCM) and observed in families with supraventricular tachycardias (SVT). Previously, a family harboring the TNNI3K-c.1615A > G (p.Thr539Ala) variant presented with congenital junctional ectopic tachycardia (CJET), an arrhythmia that arises from the atrioventricular (AV) node and His bundle. However, this was a relatively small four-generational family with limited genetic testing (N = 3). We here describe a multigenera...
Source: Clinical Genetics - March 1, 2024 Category: Genetics & Stem Cells Authors: Caroline Pham Tamara T Koopmann Jeffrey M Vinocur Nico A Blom Vivian Nogueira Silbiger Kirti Mittal Marianne Bootsma Kaylin C A Palm Sally-Ann B Clur Daniela Q C M Barge-Schaapveld Robert M Hamilton Elisabeth M Lodder Source Type: research

A new approach for heart disease detection using Motif transform-based CWT's time-frequency images with DenseNet deep transfer learning methods
CONCLUSIONS: The combined approach of MT + CWT + DenseNET yielded an impressive success rate of 99.31 %.PMID:38425179 | DOI:10.1515/bmt-2023-0580 (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - March 1, 2024 Category: Biomedical Engineering Authors: Hazret Tekin Y ılmaz Kaya Source Type: research

Reduced kinase function in two ultra-rare TNNI3K variants in families with congenital junctional ectopic tachycardia
Clin Genet. 2024 Feb 29. doi: 10.1111/cge.14504. Online ahead of print.ABSTRACTGenetic missense variants in TNNI3K, encoding troponin-I interacting kinase, have been associated with dilated cardiomyopathy (DCM) and observed in families with supraventricular tachycardias (SVT). Previously, a family harboring the TNNI3K-c.1615A > G (p.Thr539Ala) variant presented with congenital junctional ectopic tachycardia (CJET), an arrhythmia that arises from the atrioventricular (AV) node and His bundle. However, this was a relatively small four-generational family with limited genetic testing (N = 3). We here describe a multigenera...
Source: Clinical Genetics - March 1, 2024 Category: Genetics & Stem Cells Authors: Caroline Pham Tamara T Koopmann Jeffrey M Vinocur Nico A Blom Vivian Nogueira Silbiger Kirti Mittal Marianne Bootsma Kaylin C A Palm Sally-Ann B Clur Daniela Q C M Barge-Schaapveld Robert M Hamilton Elisabeth M Lodder Source Type: research

A new approach for heart disease detection using Motif transform-based CWT's time-frequency images with DenseNet deep transfer learning methods
CONCLUSIONS: The combined approach of MT + CWT + DenseNET yielded an impressive success rate of 99.31 %.PMID:38425179 | DOI:10.1515/bmt-2023-0580 (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - March 1, 2024 Category: Biomedical Engineering Authors: Hazret Tekin Y ılmaz Kaya Source Type: research

Reduced kinase function in two ultra-rare TNNI3K variants in families with congenital junctional ectopic tachycardia
Clin Genet. 2024 Feb 29. doi: 10.1111/cge.14504. Online ahead of print.ABSTRACTGenetic missense variants in TNNI3K, encoding troponin-I interacting kinase, have been associated with dilated cardiomyopathy (DCM) and observed in families with supraventricular tachycardias (SVT). Previously, a family harboring the TNNI3K-c.1615A > G (p.Thr539Ala) variant presented with congenital junctional ectopic tachycardia (CJET), an arrhythmia that arises from the atrioventricular (AV) node and His bundle. However, this was a relatively small four-generational family with limited genetic testing (N = 3). We here describe a multigenera...
Source: Clinical Genetics - March 1, 2024 Category: Genetics & Stem Cells Authors: Caroline Pham Tamara T Koopmann Jeffrey M Vinocur Nico A Blom Vivian Nogueira Silbiger Kirti Mittal Marianne Bootsma Kaylin C A Palm Sally-Ann B Clur Daniela Q C M Barge-Schaapveld Robert M Hamilton Elisabeth M Lodder Source Type: research

A new approach for heart disease detection using Motif transform-based CWT's time-frequency images with DenseNet deep transfer learning methods
CONCLUSIONS: The combined approach of MT + CWT + DenseNET yielded an impressive success rate of 99.31 %.PMID:38425179 | DOI:10.1515/bmt-2023-0580 (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - March 1, 2024 Category: Biomedical Engineering Authors: Hazret Tekin Y ılmaz Kaya Source Type: research

Gut microbiota-dependent phenylacetylglutamine in cardiovascular disease: current knowledge and new insights
AbstractPhenylacetylglutamine (PAGln) is an amino acid derivate that comes from the amino acid phenylalanine. There are increasing studies showing that the level of PAGln is associated with the risk of different cardiovascular diseases. In this review, we discussed the metabolic pathway of PAGln production and the quantitative measurement methods of PAGln. We summarized the epidemiological evidence to show the role of PAGln in diagnostic and prognostic value in several cardiovascular diseases, such as heart failure, coronary heart disease/atherosclerosis, and cardiac arrhythmia. The underlying mechanism of PAGln is now con...
Source: Frontiers of Medicine - March 1, 2024 Category: General Medicine Source Type: research

Insomnia is related to long-term atrial fibrillation recurrence following radiofrequency ablation
CONCLUSION: This study establishes a significant link between insomnia and long-term AF recurrence following radiofrequency ablation. It underscores the importance of identifying and addressing insomnia in patients with AF undergoing radiofrequency ablation.PMID:38423515 | DOI:10.1080/07853890.2024.2323089 (Source: Annals of Medicine)
Source: Annals of Medicine - February 29, 2024 Category: Internal Medicine Authors: Rui-Bin Li Ji-Dong Zhang Xiao-Ran Cui Wei Cui Source Type: research