Investigating electroencephalography signals of autism spectrum disorder (ASD) using Higuchi Fractal Dimension.
The objective of this research is to analyze the brain response for auditory/visual stimuli in Typically Developing (TD) and children with autism through electroencephalography (EEG). Brain dynamics in the EEG signal can be analyzed well with the help of nonlinear feature primitives. Recent research reveals that, application of fractal-based techniques proves to be effective to estimate of degree of nonlinearity in a signal. This research attempts to analyze the effect of brain dynamics with Higuchi Fractal Dimension (HFD). Also, the performance of the fractal based techniques depends on the selection of proper hyper-param...
Source: Biomedizinische Technik/Biomedical Engineering - August 31, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

EEG-based emotion recognition with deep convolutional neural networks.
Authors: Ozdemir MA, Degirmenci M, Izci E, Akan A Abstract The emotional state of people plays a key role in physiological and behavioral human interaction. Emotional state analysis entails many fields such as neuroscience, cognitive sciences, and biomedical engineering because the parameters of interest contain the complex neuronal activities of the brain. Electroencephalogram (EEG) signals are processed to communicate brain signals with external systems and make predictions over emotional states. This paper proposes a novel method for emotion recognition based on deep convolutional neural networks (CNNs) that are...
Source: Biomedizinische Technik/Biomedical Engineering - August 28, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A new adaptive XOR, hashing and encryption-based authentication protocol for secure transmission of the medical data in Internet of Things (IoT).
Authors: Chaudhari DA, Umamaheswari E Abstract Internet of Things (IoT) plays a prominent role in health-care of patients, which assist the physicians and patients through the assistance in effective decision-making and additionally, in the medical field, IoT plays a significant role in real-time monitoring of the patients. Even though the data provided by the IoT devices ensure the effective decision-making, the data is susceptible to the network attacks. Thus, the paper proposes an authentication protocol for enabling the secure data transmission in IoT based on three functions, such as encryption function, hashi...
Source: Biomedizinische Technik/Biomedical Engineering - August 24, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Impact of mandibular prognathism on morphology and loadings in temporomandibular joints.
The objective of the study was to compare the differences of the morphological and biomechanical characteristics of TMJs between asymptomatic subjects and patients with mandibular prognathism, and to preliminarily analyze the connection between the two kinds of characteristics. Morphological measurements and finite element analysis (FEA) corresponding to the central occlusion were carried out on the models of 13 mandibular prognathism patients and 10 asymptomatic subjects. The results indicated that the joint spaces of the patients were significantly lower than those of the asymptomatic subjects, while the stresses of pati...
Source: Biomedizinische Technik/Biomedical Engineering - August 13, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Analysis of autonomic nervous pattern in hypertension based on short-term heart rate variability.
Authors: Zhang R, Hua Z, Chen C, Liu G, Wen W Abstract Physiological studies have found that the autonomic nervous system plays an important role in controlling blood pressure values. This paper, based on machine learning approaches, analysed short-term heart rate variability to determine differences in autonomic nervous function between hypertensive patients and normal population. The electrocardiogram (ECG) of hypertensive patients are 137 ECG recordings provided by Smart Health for Assessing the Risk of Events via ECG (SHAREE database). The RR intervals of healthy subjects include the data of 18 subjects from th...
Source: Biomedizinische Technik/Biomedical Engineering - August 13, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Visual enhancement of brain cancer MRI using multiscale dyadic filter and Hilbert transformation.
Authors: Vidyarthi A Abstract The quality of the medical image plays a major role in decision making by the radiologists. There exists a visual differentiation between the normal scene color images and medical images. Due to the low illumination and unavailability of the color parameter, medical images require more attention by radiologists for decision making. In this paper a new approach is proposed that enhances the quality of the Magnetic Resonance (MR) images. Proposed approach uses the spectral information present in form of Amplitude and Frequency within the MR image slices for an enhancement. The extracted ...
Source: Biomedizinische Technik/Biomedical Engineering - August 13, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Controlled differential evolution based detection of neovascularization on optic disc using support vector machine.
Authors: Biswal B, P GP, Biswal PK Abstract The severe stage of Diabetic Retinopathy (DR) is characterized by the growth of new blood vessels which is called Neovascularization (NV). The abnormally grown blood vessels on the disc are breakable in nature thus the patient is at high risk of sudden blindness. Therefore, the significance of early and accurate detection of Neovascularization on Disc (NVD) should not be neglected. This paper presents an automatic detection of the optic disc using a Controlled Differential Evolution (CDE) algorithm. Further, the Region of Interest (ROI) is created automatically by extendi...
Source: Biomedizinische Technik/Biomedical Engineering - August 13, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

How yarn orientation limits fibrotic tissue ingrowth in a woven polyester heart valve scaffold: a case report.
Authors: Meddahi-Pelle A, Pavon-Djavid G, Chakfe N, Heim F Abstract Transcatheter Aortic Valve Implantation (TAVI) has become today a popular alternative technique to surgical valve replacement for critical patients. However, with only six years follow up on average, little is known about the long-term durability of transcatheter implanted biological tissue. Moreover, the high cost of tissue harvesting and chemical treatment procedures favor the development of alternative synthetic valve leaflet materials. In that context, thin, strong and flexible woven fibrous constructions could be considered as interesting cand...
Source: Biomedizinische Technik/Biomedical Engineering - August 4, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Detection of skin cancer with adaptive fuzzy classifier using improved whale optimization.
Authors: Durgarao N, Sudhavani G Abstract Skin cancer is considered as a well-known type of cancer globally, and its occurrence has been found to be raised in current days. Researchers state that the disease requires early prediction so that the identification of precise signs will make it simple for the dermatologists and clinicians. This disorder has been established to be unpredictable. Hence, this paper intends to develop an efficient skin cancer detection scheme, which classifies the nature of cancer, whether it is normal, benign or malignant. Accordingly, the skin image which is given as input is segmented us...
Source: Biomedizinische Technik/Biomedical Engineering - July 29, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Sparse-FCM and Deep Convolutional Neural Network for the segmentation and classification of acute lymphoblastic leukaemia.
Authors: Praveena S, Singh SP Abstract Leukaemia detection and diagnosis in advance is the trending topic in the medical applications for reducing the death toll of patients with acute lymphoblastic leukaemia (ALL). For the detection of ALL, it is essential to analyse the white blood cells (WBCs) for which the blood smear images are employed. This paper proposes a new technique for the segmentation and classification of the acute lymphoblastic leukaemia. The proposed method of automatic leukaemia detection is based on the Deep Convolutional Neural Network (Deep CNN) that is trained using an optimization algorithm, ...
Source: Biomedizinische Technik/Biomedical Engineering - July 28, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Workflow and hardware for intraoperative hyperspectral data acquisition in neurosurgery.
Authors: Mühle R, Ernst H, Sobottka SB, Morgenstern U Abstract To prevent further brain tumour growth, malignant tissue should be removed as completely as possible in neurosurgical operations. Therefore, differentiation between tumour and brain tissue as well as detecting functional areas is very important. Hyperspectral imaging (HSI) can be used to get spatial information about brain tissue types and characteristics in a quasi-continuous reflection spectrum. In this paper, workflow and some aspects of an adapted hardware system for intraoperative hyperspectral data acquisition in neurosurgery are discussed. B...
Source: Biomedizinische Technik/Biomedical Engineering - July 28, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A simple model to detect atrial fibrillation via visual imaging.
In this study we proposed and validated a model to identify AF by using facial video recordings. We analyzed photoplethysmographic imaging (PPGi) signals, extracted from video of a subject's face. Sixty-eight patients were included: 30 in sinus rhythm (SR), 25 in AF and 13 presenting with atrial flutter or frequent ectopic beats (ARR). Twenty-six indexes were computed. The dataset was divided in three subsets: the training, validation, and test set, containing, respectively, 58, 29, and 13% of the data. Mean of inter-systolic interval series (M), Local Maxima Similarity (LMS), and pulse harmonic strength (PHS) indexes were...
Source: Biomedizinische Technik/Biomedical Engineering - July 15, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Design of a wearable four-channel near-infrared spectroscopy system for the measurement of brain hemodynamic responses.
Conclusions The developed four-channel NIRS system is user-friendly and has been designed with inexpensive components, unlike the commercially available NIRS instruments that are cumbersome and expensive. PMID: 32649290 [PubMed - as supplied by publisher] (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - July 12, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Scalp electroencephalography (sEEG) based advanced prediction of epileptic seizure time and identification of epileptogenic region.
Authors: Sharma A, Rai JK, Tewari RP Abstract Objectives Epilepsy is characterized by uncontrollable seizure during which consciousness of patient is disturbed. Prediction of the seizure in advance will increase the remedial possibilities for the patients suffering from epilepsy. An automated system for seizure prediction is important for seizure enactment, prevention of sudden unexpected deaths and to avoid seizure related injuries. Methods This paper proposes the prediction of an upcoming seizure by analyzing the 23 channel non-stationary EEG signal. EEG signal is divided into smaller segments to change it into q...
Source: Biomedizinische Technik/Biomedical Engineering - July 8, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A microelectromechanical system (MEMS) capacitive accelerometer-based microphone with enhanced sensitivity for fully implantable hearing aid: a novel analytical approach.
Authors: Dwivedi A, Khanna G Abstract The present work proposes a novel, compact, intuitively simple and efficient structure to improve the sensitivity of a microelectromechanical system (MEMS) capacitive accelerometer using an arrangement of microlever as a displacement amplifier. The accelerometer is proposed to serve as a microphone in the fully implantable cochlear prosthetic system which can be surgically implanted at the middle ear bone structure. Therefore, the design parameters such as size, weight and resonant frequency require deliberation. The paper presents a novel analytical model considering the impac...
Source: Biomedizinische Technik/Biomedical Engineering - July 7, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

EEG Source Imaging (ESI) utility in clinical practice.
Authors: Khosropanah P, Ho ET, Lim KS, Fong SL, Thuy Le MA, Narayanan V Abstract Epilepsy surgery is an important treatment modality for medically refractory focal epilepsy. The outcome of surgery usually depends on the localization accuracy of the epileptogenic zone (EZ) during pre-surgical evaluation. Good localization can be achieved with various electrophysiological and neuroimaging approaches. However, each approach has its own merits and limitations. Electroencephalography (EEG) Source Imaging (ESI) is an emerging model-based computational technique to localize cortical sources of electrical activity within t...
Source: Biomedizinische Technik/Biomedical Engineering - July 7, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Analysis of statistical coefficients and autoregressive parameters over intrinsic mode functions (IMFs) for epileptic seizure detection.
Authors: Djemili R Abstract Epilepsy is a persistent neurological disorder impacting over 50 million people around the world. It is characterized by repeated seizures defined as brief episodes of involuntary movement that might entail the human body. Electroencephalography (EEG) signals are usually used for the detection of epileptic seizures. This paper introduces a new feature extraction method for the classification of seizure and seizure-free EEG time segments. The proposed method relies on the empirical mode decomposition (EMD), statistics and autoregressive (AR) parameters. The EMD method decomposes an EEG ti...
Source: Biomedizinische Technik/Biomedical Engineering - July 4, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Integrating artificial neural network and scoring systems to increase the prediction accuracy of patient mortality and organ dysfunction.
Authors: Noorbakhsh SA, Mahmoodi-Eshkaftaki M, Mokhtari Z Abstract The aim of this study was to develop and compare techniques to increase the prediction accuracy of patient mortality and organ dysfunction in the Intensive Care Units (hereinafter ICU) of hospitals. Patient mortality was estimated with two models of artificial neural network (ANN)-backpropagation (BP) and simplified acute physiology score (SAPS). Organ dysfunction was predicted by coupled ANN self-organizing map (SOM) and logistic organ dysfunction score (LODS) method on the basis of patient conditions. Input dataset consisted of 36 features recorde...
Source: Biomedizinische Technik/Biomedical Engineering - July 2, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

An integrated assessment system for the accreditation of medical laboratories.
Authors: Saleh N, Abo Agyla A Abstract Medical laboratory accreditation becomes a trend to be trustable for diagnosis of diseases. It is always performed at regular intervals to assure competence of quality management systems (QMS) based on pre-defined standards. However, few attempts were carried out to assess the quality level of medical laboratory services. Moreover, there is no realistic study that classifies and makes analyses of laboratory performance based on a computational model. The purpose of this study was to develop an integrated system for medical laboratory accreditation that assesses QMS against ISO...
Source: Biomedizinische Technik/Biomedical Engineering - July 2, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Replication of left ventricular haemodynamics with a simple planar mitral valve model.
Authors: Daub A, Kriegseis J, Frohnapfel B Abstract Tools for the numerical prediction of haemodynamics in multi-disciplinary integrated heart simulations have to be based on computational models that can be solved with low computational effort and still provide physiological flow characteristics. In this context the mitral valve model is important since it strongly influences the flow kinematics, especially during the diastolic phase. In contrast to a 3D valve, a vastly simplified valve model in form of a simple diode is known to be unable to reproduce the characteristic vortex formation and unable to promote a pr...
Source: Biomedizinische Technik/Biomedical Engineering - July 2, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Age dependency of the diabetes effects on the iris recognition systems performance evaluation results.
Authors: Azimi M, Rasoulinejad SA, Pacut A Abstract In this paper, we attempt to answer the questions whether iris recognition task under the influence of diabetes would be more difficult and whether the effects of diabetes and individuals' age are uncorrelated. We hypothesized that the health condition of volunteers plays an important role in the performance of the iris recognition system. To confirm the obtained results, we reported the distribution of usable area in each subgroup to have a more comprehensive analysis of diabetes effects. There is no conducted study to investigate for which age group (young or ol...
Source: Biomedizinische Technik/Biomedical Engineering - July 2, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A multi-source co-frequency stimulus method for electroencephalogram (EEG) enhancement.
Authors: Yan W, Xu G Abstract The electroencephalogram (EEG) induced by steady-state visual evoked potential (SSVEP) will contain background noise. Most existing research on this problem uses signal-processing methods to enhance the EEG. The purpose of this paper is to explore another method that can be used to enhance the EEG. We creatively combined motion stimuli with light-flashing stimuli and designed a paradigm in which motion and light-flashing simultaneously will stimulate with the same frequency; this is called multi-source co-frequency stimulus. To avoid the direct stimulus of light-flashing in the human e...
Source: Biomedizinische Technik/Biomedical Engineering - July 2, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A review of foot pose and trajectory estimation methods using inertial and auxiliary sensors for kinematic gait analysis.
Authors: Okkalidis N, Camilleri KP, Gatt A, Bugeja MK, Falzon O Abstract The use of foot mounted inertial and other auxiliary sensors for kinematic gait analysis has been extensively investigated during the last years. Although, these sensors still yield less accurate results than those obtained employing optical motion capture systems, the miniaturization and their low cost have allowed the estimation of kinematic spatiotemporal parameters in laboratory conditions and real life scenarios. The aim of this work was to present a comprehensive approach of this scientific area through a systematic literature research, ...
Source: Biomedizinische Technik/Biomedical Engineering - June 28, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Insertion torque/time integral as a measure of primary implant stability.
Authors: Grobecker-Karl T, Karl M, Steiner C Abstract The goal of this in vitro study was to determine the insertion torque/time integral for three implant systems. Bone level implants (n = 10; BLT - Straumann Bone Level Tapered 4.1 mm × 12 mm, V3 - MIS V3 3.9 mm × 11.5 mm, ASTRA - Dentsply-Sirona ASTRA TX 4.0 mm × 13 mm) were placed in polyurethane foam material consisting of a trabecular and a cortical layer applying protocols for medium quality bone. Besides measuring maximum insertion torque and primary implan...
Source: Biomedizinische Technik/Biomedical Engineering - June 28, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Mathematical model of patella T-reflex and clinical evaluation with Ashworth scales.
In this study, the spasticity mechanism which develops concerning the upper motor neuron lesions is investigated by modelling "Patella tendon reflex triggered patella pendulum". The mathematical model based on the pendulum phenomenon is developed by solving the curve-fitting problem as finding the curve that best fits a set of data points. Electrophysiological and dynamic measurement data were taken from 76 spastic subjects and 20 healthy participants. The mathematical model is determined by the morphological properties of the goniometric variations. The results denote that the mathematical model containing two c...
Source: Biomedizinische Technik/Biomedical Engineering - June 19, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A novel non-invasive method for estimating the local wave speed at a single site in the internal carotid artery.
Authors: Ayadi A, Sahtout W, Baledent O Abstract Objectives Local wave speed is a biomarker which provides an objective analysis of the cardiovascular function. The aim of this study was to determine the local wave speed in the internal carotid artery by a new non-invasive method that measures blood velocity waveform at only one site. Methods For this purpose, the cepstral analysis was employed to determine the arrival time of the reflection wave and the wave speed in the carotid artery. To validate our model, we applied it experimentally in vivo on young and old healthy subjects. The blood velocity waveform was me...
Source: Biomedizinische Technik/Biomedical Engineering - May 29, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Classification of standing and sitting phases based on in-socket piezoelectric sensors in a transfemoral amputee.
Authors: Yahya T, Hamzaid NA, Ali S, Jasni F, Shasmin HN Abstract A transfemoral prosthesis is required to assist amputees to perform the activity of daily living (ADL). The passive prosthesis has some drawbacks such as utilization of high metabolic energy. In contrast, the active prosthesis consumes less metabolic energy and offers better performance. However, the recent active prosthesis uses surface electromyography as its sensory system which has weak signals with microvolt-level intensity and requires a lot of computation to extract features. This paper focuses on recognizing different phases of sitting and st...
Source: Biomedizinische Technik/Biomedical Engineering - May 29, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

The performance of a low-cost bio-amplifier on 3D human arm movement reconstruction.
Conclusions This study has shown that low-cost bio-amplifiers such as the OpenBCI can be used for 3D motion reconstruction tasks. PMID: 32463379 [PubMed - as supplied by publisher] (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - May 29, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Frequency decomposition and phase synchronization of the visual evoked potential using the empirical mode decomposition.
Conclusions The VEP signals decomposed into constituent frequency components through phase analysis can be used as a method of analyzing the relationship between activated signals and brain function related to visual stimuli. PMID: 32463380 [PubMed - as supplied by publisher] (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - May 29, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A novel motion coupling coding method for brain-computer interfaces.
Conclusions The proposed method has been evaluated to have substantial potential for increasing the number of coding targets, which is an effective supplement to the existing studies. PMID: 32463381 [PubMed - as supplied by publisher] (Source: Biomedizinische Technik/Biomedical Engineering)
Source: Biomedizinische Technik/Biomedical Engineering - May 29, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Osteoclast and osteoblast response to strontium-doped struvite coatings on titanium for improved bone integration.
Authors: Moseke C, Wimmer K, Meininger M, Zerweck J, Wolf-Brandstetter C, Gbureck U, Ewald A Abstract To develop implants with improved bone ingrowth, titanium substrates were coated with homogeneous and dense struvite (MgNH4PO4·6H2O) layers by means of electrochemically assisted deposition. Strontium nitrate was added to the coating electrolyte in various concentrations, in order to fabricate Sr-doped struvite coatings with Sr loading ranging from 10.6 to 115 μg/cm2. It was expected and observed that osteoclast activity surrounding the implant was inhibited. The cytocompatibility of the coatings and...
Source: Biomedizinische Technik/Biomedical Engineering - May 28, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Electrocardiography (ECG) analysis and a new feature extraction method using wavelet transform with scalogram analysis.
In this study, an ECG analysis toolbox together with a user-friendly graphical user interface, which contains the all ECG analysis steps between the recording unit and the statistical investigation, is developed. Furthermore, a new feature calculation methodology is proposed for ECG analysis, which carries distinct information than amplitudes and durations of ECG main waves and can be used in artificial intelligence studies. Developed toolbox is tested using both Massachusetts Institute of Technology-Beth Israel Hospital (MIT-BIH) Arrhythmia ECG Database and an experimentally collected dataset for performance evaluation. T...
Source: Biomedizinische Technik/Biomedical Engineering - May 23, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Does preconditioning lower the rupture resistance of chorioamniotic membrane?
Authors: Dadkhah A, Hashemi A Abstract Premature rupture of fetal membrane occurs in about 3% of all pregnancies. The physical integrity of chorioamnion (CA) membrane should be retained until delivery for a healthy pregnancy. To explore the effect of pre-conditioning and probe size on the mechanical properties of human chorioamniotic sac, the mechanical properties of 17 human chorioamniotic membranes, collected from cesarean delivery, were examined using biaxial puncture tests with and without preconditioning by different probe sizes. For preconditioned samples, the mean ± std. of ultimate rupture ...
Source: Biomedizinische Technik/Biomedical Engineering - May 22, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Developing a novel resorptive hydroxyapatite-based bone substitute for over-critical size defect reconstruction: physicochemical and biological characterization and proof of concept in segmental rabbit's ulna reconstruction.
Authors: Micic M, Antonijevic D, Milutinovic-Smiljanic S, Trisic D, Colovic B, Kosanovic D, Prokic B, Vasic J, Zivkovic S, Milasin J, Danilovic V, Djuric M, Jokanovic V Abstract The aim of this study was to develop novel hydroxyapatite (HAP)-based bioactive bone replacement materials for segmental osteotomy reconstruction. Customized three-dimensional (3D) bone construct was manufactured from nanohydroxyapatite (nHAP) with poly(lactide-co-glycolide) (PLGA) coating using 3D models derived from the computed tomography (CT) scanning of the rabbit's ulna and gradient 3D printing of the bone substitute mimicking the ana...
Source: Biomedizinische Technik/Biomedical Engineering - April 28, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Titanium coating: introducing an antibacterial and bioactive chitosan-alginate film on titanium by spin coating.
In this study, pure Ti implants were coated via chitosan and alginate by spin coating method at 1000, 4000, and 8000 rpm. The coating layer was cross-linked by calcium chloride. Their chemical structures were analyzed by Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) evaluations. The morphology of the created coating was observed by scanning electron microscopy (SEM), and the best uniformity was observed in the prepared coating at 8000 rpm (6093× g) spinal speed. The adhesion strength of the coating layer on the substrate was evaluated by the adhesion pull-off test. Also, the best adhesion...
Source: Biomedizinische Technik/Biomedical Engineering - April 26, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Electrical stimulator with mechanomyography-based real-time monitoring, muscle fatigue detection, and safety shut-off: a pilot study.
Authors: Naeem J, Hamzaid NA, Azman AW, Bijak M Abstract Functional electrical stimulation (FES) has been used to produce force-related activities on the paralyzed muscle among spinal cord injury (SCI) individuals. Early muscle fatigue is an issue in all FES applications. If not properly monitored, overstimulation can occur, which can lead to muscle damage. A real-time mechanomyography (MMG)-based FES system was implemented on the quadriceps muscles of three individuals with SCI to generate an isometric force on both legs. Three threshold drop levels of MMG-root mean square (MMG-RMS) feature (thr50, thr60, and thr7...
Source: Biomedizinische Technik/Biomedical Engineering - April 19, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A nonlinear dynamical approach to analysis of emotions using EEG signals based on the Poincar é map function and recurrence plots.
In this study, we have applied two different recurrence-based chaotic schemes, namely the Poincaré map function and recurrence plots (RPs), to analyze the long-term dynamics of EEG signals associated with state space (SS) trajectory of the time series. Both approaches determine the system dynamics based on the Poincaré recurrence theorem as well as the trajectory divergence producing two-dimensional (2D) characteristic plots. The performance of the methods is compared with regard to their ability to distinguish between levels of valence, arousal, dominance and liking using EEG data from the "dataset for ...
Source: Biomedizinische Technik/Biomedical Engineering - April 16, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Properties of different types of dry electrodes for wearable smart monitoring devices.
Authors: Popović-Maneski L, Ivanović MD, Atanasoski V, Miletić M, Zdolšek S, Bojović B, Hadžievski L Abstract Wearable smart monitors (WSMs) applied for the estimation of electrophysiological signals are of utmost interest for a non-stressed life. WSM which records heart muscle activities could signalize timely a life-threatening event. The heart muscle activities are typically recorded across the heart at the surface of the body; hence, a WSM monitor requires high-quality surface electrodes. The electrodes used in the clinical settings [i.e. silver/silver chloride (Ag/AgCl) with the gel] are not practi...
Source: Biomedizinische Technik/Biomedical Engineering - April 3, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Matching pursuit algorithm for enhancing EEG signal quality and increasing the accuracy and efficiency of emotion recognition.
Authors: Momennezhad A Abstract In this paper, we suggest an efficient, accurate and user-friendly brain-computer interface (BCI) system for recognizing and distinguishing different emotion states. For this, we used a multimodal dataset entitled "MAHOB-HCI" which can be freely reached through an email request. This research is based on electroencephalogram (EEG) signals carrying emotions and excludes other physiological features, as it finds EEG signals more reliable to extract deep and true emotions compared to other physiological features. EEG signals comprise low information and signal-to-noise ratios ...
Source: Biomedizinische Technik/Biomedical Engineering - April 3, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A Matlab toolbox for analyzing repetitive movements: application in gait and tapping experiments.
Authors: Kirlangic ME, Al-Qadhi S, Hauptmann C, Freund HJ Abstract Coordination and timing in repetitive movements have been intensively investigated in diverse experimental settings for understanding the underlying basic mechanisms in healthy controls. On this basic research side, there are mainly two theoretical models: the Wing-Kristofferson (WK) model and the Haken-Kelso-Bunz (HKB) model. On the clinical side of the research, several efforts have been spent on quantitatively assessing gait and other repetitive movements such as tapping, especially as an outcome measure of clinical trials in diverse neurological...
Source: Biomedizinische Technik/Biomedical Engineering - February 3, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Adolescent age estimation using voice features.
Authors: Bugdol MD, Bugdol MN, Bieńkowska MJ, Lipowicz A, Wijata AM, Mitas AW Abstract In this paper, a method for evaluating the chronological age of adolescents on the basis of their voice signal is presented. For every examined child, the vowels a, e, i, o and u were recorded in extended phonation. Sixty voice parameters were extracted from each recording. Voice recordings were supplemented with height measurement in order to check if it could improve the accuracy of the proposed solution. Predictor selection was performed using the LASSO (least absolute shrinkage and selection operator) algorithm. For age esti...
Source: Biomedizinische Technik/Biomedical Engineering - January 16, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Non-invasive drug delivery technology: development and current status of transdermal drug delivery devices, techniques and biomedical applications.
Authors: Akhtar N, Singh V, Yusuf M, Khan RA Abstract Pay-load deliveries across the skin barrier to the systemic circulation have been one of the most challenging delivery options. Necessitated requirements of the skin and facilitated skin layer cross-over delivery attempts have resulted in development of different non-invasive, non-oral methods, devices and systems which have been standardized, concurrently used and are in continuous upgrade and improvements. Iontophoresis, electroporation, sonophoresis, magnetophoresis, dermal patches, nanocarriers, needled and needle-less shots, and injectors are among some of ...
Source: Biomedizinische Technik/Biomedical Engineering - January 13, 2020 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

A comprehensive evaluation for the prediction of mortality in intensive care units with LSTM networks: patients with cardiovascular disease.
We present the application of LSTM and LSTM attention (LSTM-AT) model for mortality prediction with such a large number of clinical variables dataset. For training and validation purpose, we have used International Classification of Diseases, 9th edition (ICD-9) codes for extracting the patients with cardiovascular disease, and infections and parasitic disease, respectively. The effectiveness of the LSTM model is achieved over non-recurrent baseline models like naïve Bayes, logistic regression (LR), support vector machine and multilayer perceptron (MLP) by generating state of the art results (area under the curve [AUC...
Source: Biomedizinische Technik/Biomedical Engineering - December 18, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Dual-frequency bioelectrical phase angle to estimate the platelet count for the prognosis of dengue fever in Indian children.
Authors: Devarasu N, Sudha GF Abstract A noninvasive investigation to ascertain the platelet (PLT) count was conducted on 44 hospitalized dengue hemorrhagic fever (DHF) subjects, male and female aged between 3 and 14 years using bioelectrical phase angle (BPhA). Among the 44 subjects, 30 subjects were confirmed to be non-structural protein-1 (NS1) positive at the time of admission, whose blood investigations such as hematocrit (HCT) level, PLT count, aspartate aminotransferase (AST) level and alanine aminotransferase (ALT) level were performed for the classification of risk as low-risk (LR) and high-risk (HR) DHF. ...
Source: Biomedizinische Technik/Biomedical Engineering - December 14, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Optimisation of the drill-in behaviour of the EcoFit ® SC threaded cup.
Optimisation of the drill-in behaviour of the EcoFit® SC threaded cup. Biomed Tech (Berl). 2019 Dec 13;: Authors: Thorwächter C, Woiczinski M, Santos I, Schmidutz F, Paulus A, Jansson V, Weber P Abstract Threaded cups show good clinical results when implanted correctly. In clinical use, multiple cases with an incomplete placement of the EcoFit threaded cup (implantcast) were observed. This behaviour could not be explained intra- and postoperatively. The aim of this study was to compare and optimise the drill-in-behaviour of the EcoFit cup in a biomechanical investigation. EcoFit cup sizes 46, ...
Source: Biomedizinische Technik/Biomedical Engineering - December 14, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Objectivization of vacuum-compression therapy effects on micro- and macrovascular perfusion in type 2 diabetic patients.
Authors: Prucha J, Socha V, Hanakova L, Lalis A, Hana K Abstract The present study aimed to evaluate the characteristic influence of physical therapeutic procedures of vacuum-compression therapy (VCT) on microvascular perfusion (MiP) and macrovascular perfusion (MaP) of the lower limb in diabetic patients. A sample of nine patients with a medical history of type 2 diabetes was used for the purpose of this study. Most of the subjects' medical conditions included venous and neurological complications of the lower limb, whereas the rest of the subjects entered the treatment due to injury recovery or their phlebologica...
Source: Biomedizinische Technik/Biomedical Engineering - December 14, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Evaluation of potential auras in generalized epilepsy from EEG signals using deep convolutional neural networks and time-frequency representation.
In this study, it was aimed to evaluate pre-seizure warning symptoms of the electroencephalography (EEG) signals by a convolutional neural network (CNN) inspired by the epileptic auras defined in the medical field. In this context, one-dimensional EEG signals were transformed into a spectrogram display form in the frequency-time domain by applying a short-time Fourier transform (STFT). Systemic changes in pre-epileptic seizure have been described by applying the CNN approach to the EEG signals represented in the image form, and the subjective EEG-Aura process has been tried to be determined for each patient. Considering al...
Source: Biomedizinische Technik/Biomedical Engineering - December 13, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Thermography and colour Doppler ultrasound: a potential complementary diagnostic tool in evaluation of rheumatoid arthritis in the knee region.
Authors: Umapathy S, Thulasi R, Gupta N, Sivanadhan S Abstract The aim and objectives of this study were as follows: (i) to perform automated segmentation of knee thermal image using the regional isotherm-based segmentation (RIBS) algorithm and segmentation of ultrasound image using the image J software; (ii) to implement the RIBS algorithm using computer-aided diagnostic (CAD) tools for classification of rheumatoid arthritis (RA) patients and normal subjects based on feature extraction values; and (iii) to correlate the extracted thermal imaging features and colour Doppler ultrasound (CDUS) features in the knee re...
Source: Biomedizinische Technik/Biomedical Engineering - December 11, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

Realisation and assessment of a low-cost LED device for contact lens disinfection by visible violet light.
This study presents a device for efficient, low-cost and eye-friendly overnight disinfection of contact lenses by visible violet light as an alternative to disinfection with biocide-containing solutions. Bacterial solutions with one Pseudomonas and one Staphylococcus strain each were irradiated for up to 8 h in commercial transparent contact lens cases by the presented light-emitting diode (LED) device. Samples were taken at different intervals and distributed on agar plates. The surviving bacteria were determined by counting of colony-forming units and compared to the specific requirements of the stand-alone test for cont...
Source: Biomedizinische Technik/Biomedical Engineering - December 8, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research

The effectiveness of the choice of criteria on the stationary and non-stationary noise removal in the phonocardiogram (PCG) signal using discrete wavelet transform.
Authors: Rouis M, Sbaa S, Benhassine NE Abstract The greatest problem with recording heart sounds is parasitic noise effects. A reasonable solution to reduce noise can be carried out by minimization of extraneous noises in the vicinity of the patient during recording, in addition to the methods of signal processing that must be effective in noisy environments. Wavelet transform has become an essential tool for many applications, but its effectiveness is influenced by main parameters. Determination of mother wavelet function and decomposition level (DL) are important key factors to demonstrate the advantages of wave...
Source: Biomedizinische Technik/Biomedical Engineering - December 1, 2019 Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research