The predictive value of NLR, PLR and MLR in the differential diagnosis of benign uterine diseases and endometrial malignant tumors
CONCLUSIONS: In peripheral blood, NLR, PLR and MLR have certain diagnostic value in the differential diagnosis of endometrial cancer. When NLR, PLR and MLR are elevated, we should be alert to the occurrence of endometrial malignant tumors, and the combined diagnostic efficiency is high.PMID:38555539 | DOI:10.1007/s12672-024-00956-8 (Source: Cancer Control)
Source: Cancer Control - March 31, 2024 Category: Cancer & Oncology Authors: Lin Qin Source Type: research
Alterations of UHRF family Expression and was regulated by High Risk Type HPV16 in Uterine Cervical Cancer
In this study, we analyzed the UHRF family expression in cervical cancers, and it's regulation by human papillomavirus (HPV). Western blotting was performed to analyze protein expression in cervical cancer cell lines. Immunohistochemical analysis were used to investigate the expression of UHRF family and MIB-1 in cervical cancer tissues. Transfection were done for analyze the relationship between UHRF family and HPVs. We showed that NIRF expression was decreased and ICBP90 expression was increased in cervical cancers compared to normal counterparts. Western blotting also showed that NIRF expression was quite low levels, bu...
Source: Experimental Cell Research - March 31, 2024 Category: Cytology Authors: Masafumi Yoshimoto Aoi Tokuda Ayami Eguchi Yoshihiro Nozawa Tsutomu Mori Yuji Yaginuma Source Type: research
High-dose ascorbate exerts anti-tumor activities and improves inhibitory effect of carboplatin through the pro-oxidant function pathway in uterine serous carcinoma cell lines
CONCLUSIONS: Ascorbate has potent antitumor activity and acts synergistically with carboplatin through its pro-oxidant effects. Clinical trials of ascorbate combined with carboplatin as adjuvant treatment of uterine serous carcinoma are worth exploring.PMID:38555710 | DOI:10.1016/j.ygyno.2024.03.021 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 31, 2024 Category: Cancer & Oncology Authors: Xiaochang Shen Jiandong Wang Boer Deng Shuning Chen Catherine John Ziyi Zhao Nikita Sinha Jennifer Haag Wenchuan Sun Weimin Kong Ivan Spasojevic Ines Batinic-Haberle Angeles Alvarez Secord Chunxiao Zhou Victoria L Bae-Jump Source Type: research
High-dose ascorbate exerts anti-tumor activities and improves inhibitory effect of carboplatin through the pro-oxidant function pathway in uterine serous carcinoma cell lines
CONCLUSIONS: Ascorbate has potent antitumor activity and acts synergistically with carboplatin through its pro-oxidant effects. Clinical trials of ascorbate combined with carboplatin as adjuvant treatment of uterine serous carcinoma are worth exploring.PMID:38555710 | DOI:10.1016/j.ygyno.2024.03.021 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 31, 2024 Category: Cancer & Oncology Authors: Xiaochang Shen Jiandong Wang Boer Deng Shuning Chen Catherine John Ziyi Zhao Nikita Sinha Jennifer Haag Wenchuan Sun Weimin Kong Ivan Spasojevic Ines Batinic-Haberle Angeles Alvarez Secord Chunxiao Zhou Victoria L Bae-Jump Source Type: research
High-dose ascorbate exerts anti-tumor activities and improves inhibitory effect of carboplatin through the pro-oxidant function pathway in uterine serous carcinoma cell lines
CONCLUSIONS: Ascorbate has potent antitumor activity and acts synergistically with carboplatin through its pro-oxidant effects. Clinical trials of ascorbate combined with carboplatin as adjuvant treatment of uterine serous carcinoma are worth exploring.PMID:38555710 | DOI:10.1016/j.ygyno.2024.03.021 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - March 31, 2024 Category: Cancer & Oncology Authors: Xiaochang Shen Jiandong Wang Boer Deng Shuning Chen Catherine John Ziyi Zhao Nikita Sinha Jennifer Haag Wenchuan Sun Weimin Kong Ivan Spasojevic Ines Batinic-Haberle Angeles Alvarez Secord Chunxiao Zhou Victoria L Bae-Jump Source Type: research
The predictive value of NLR, PLR and MLR in the differential diagnosis of benign uterine diseases and endometrial malignant tumors
ConclusionsIn peripheral blood, NLR, PLR and MLR have certain diagnostic value in the differential diagnosis of endometrial cancer. When NLR, PLR and MLR are elevated, we should be alert to the occurrence of endometrial malignant tumors, and the combined diagnostic efficiency is high. (Source: Hormones and Cancer)
Source: Hormones and Cancer - March 31, 2024 Category: Cancer & Oncology Source Type: research
Significance of platelet parameters in invasive squamous cell carcinoma of uterine cervix
CONCLUSION: Platelet parameters are importance in cervical cancer. PLR, platelet count, and PCT are platelet parameters that can be used as predictors and prognostic parameters in cervical cancer. These parameters are cost-effective and can be considered in low resource settings. However, a multicentric study with a larger sample size should be done to extrapolate the findings for patient care.PMID:38554311 | DOI:10.4103/jcrt.jcrt_217_22 (Source: Cell Research)
Source: Cell Research - March 30, 2024 Category: Cytology Authors: Ankit Anand Kalyani Raju Source Type: research
Grinning robots, hyena hierarchies, and more stories you might have missed this week
Could a spicy cocktail be good for your gut? How did scientists manage to peer inside a mouse’s womb? And why did a researcher in Spain cover acorns with human pee? Check out the answers below in some of our favorite selections from
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One julep, please—and make it spicy
If you’re a cocktail connoisseur, you may have noticed that spicy drinks have boomed in popularity in recent years. Pepper-infused liquors have become hot ingredients in everything from martinis to mules. Even beer brewers have gotten in...
Source: Science of Aging Knowledge Environment - March 29, 2024 Category: Geriatrics Source Type: research
Recent advances in photodynamic therapy combined with chemotherapy for cervical cancer: a systematic review
CONCLUSION: Despite the scarcity of animal studies and the absence of clinical studies, the combination of chemotherapy with PDT presents a potential option for cervical cancer therapy requiring additional studies.OSF REGISTRATION: https://doi.org/10.17605/OSF.IO/WPHN5.PMID:38549400 | DOI:10.1080/14737140.2024.2337259 (Source: Expert Review of Anticancer Therapy)
Source: Expert Review of Anticancer Therapy - March 29, 2024 Category: Cancer & Oncology Authors: Lucimara Rodrigues Carobeli Ana Beatriz Camillo Santos Laura Beatriz Marques Martins Edilson Damke Marcia Edilaine Lopes Consolaro Source Type: research
Recent advances in photodynamic therapy combined with chemotherapy for cervical cancer: a systematic review
CONCLUSION: Despite the scarcity of animal studies and the absence of clinical studies, the combination of chemotherapy with PDT presents a potential option for cervical cancer therapy requiring additional studies.OSF REGISTRATION: https://doi.org/10.17605/OSF.IO/WPHN5 [Figure: see text].PMID:38549400 | DOI:10.1080/14737140.2024.2337259 (Source: Expert Review of Anticancer Therapy)
Source: Expert Review of Anticancer Therapy - March 29, 2024 Category: Cancer & Oncology Authors: Lucimara Rodrigues Carobeli Ana Beatriz Camillo Santos Laura Beatriz Marques Martins Edilson Damke Marcia Edilaine Lopes Consolaro Source Type: research
