Survival among treated tongue cancer patients: a single-center experience
ConclusionsIn tongue cancer patients, overall and specific survival were reduced in the presence of infiltrated resection margins. Lymphadenectomy in turn improved survival compared with patients in which this procedure was not carried out. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 23, 2024 Category: Cancer & Oncology Source Type: research
Comparison of clinicopathological and prognostic features of breast cancer patients younger than 40 years and older than 65 years
ConclusionTo our knowledge, no study directly compares these two groups. In our study, similar to many studies, more aggressive tumor features were found in young patients, but unlike many studies, mortality was found to be significantly higher in older patients. The presence of metastasis and poor ECOG PS were found to be the most influential factors in breast cancer-specific death risk. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 22, 2024 Category: Cancer & Oncology Source Type: research
HBO regulates the Warburg effect of hypoxic HCC cells through miR-103a-3p/TRIM35
ConclusionThese findings reveal that HBO regulates the Warburg effect of hypoxic HCC cells through miR-103a-3p/TRIM35 and inhibits tumor growth. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 20, 2024 Category: Cancer & Oncology Source Type: research
SLC35A2 expression is associated with HER2 expression in breast cancer
This study aimed to investigate the expression of SLC35A2 and clinicopathological variables in breast cancer patients. Immunohistochemical analysis of SLC35A2 protein was conductedon 40 adjacent non-neoplastic tissues and 320 breast cancer tissues. The study also assesed the association between SLC35A2 expression and breast cancer clinicopathological features of breast cancer, as well as its impact on overall survival. In comparison to adjacent non-neoplastic tissues, a significantly higher expression of SLC35A2 was observed in breast cancer tissues (P = 0.020), and this expression was found to be independently correla...
Source: Hormones and Cancer - April 19, 2024 Category: Cancer & Oncology Source Type: research
The clinical significance and oncogenic function of LRRFIP1 in pancreatic cancer
ConclusionTaken together, LRRFIP1 is associated with tumorigenesis, immune cell infiltration, and prognosis in pancreatic cancer, which suggests that LRRFIP1 may be a potential biomarker and therapeutic target for pancreatic cancer. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 18, 2024 Category: Cancer & Oncology Source Type: research
Prediction of prostate cancer aggressiveness using magnetic resonance imaging radiomics: a dual-center study
ConclusionsMRI radiomics models are suitable for predicting GS and positive needles of systematic biopsy in PCa. The models can be used to identify aggressive PCa using a noninvasive, repeatable, and accurate diagnostic method. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 16, 2024 Category: Cancer & Oncology Source Type: research
Circular RNA COL1A1 promotes Warburg effect and tumor growth in nasopharyngeal carcinoma
ConclusionTo conclude, our findings delineate that circCOL1A1 exerts its oncogenic influence in NPC through the modulation of the miR-370-5p/PTMA signaling axis. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 15, 2024 Category: Cancer & Oncology Source Type: research
T cell-mediated tumor killing sensitivity gene signature-based prognostic score for acute myeloid leukemia
ConclusionA T-cell mediated killing sensitivity gene-based prognostic score TTKPI showed good accuracy in predicting survival in AML. TTKPI corresponded to functional and immunological features of the tumor microenvironment including checkpoint expression patterns and should be investigated for precision medicine approaches. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 15, 2024 Category: Cancer & Oncology Source Type: research
Immune-related LncRNAs scores predicts chemotherapeutic responses and prognosis in cervical cancer patients
ConclusionsAn eight-IRlncRs-based prediction model was identified that has the potential to be an important tool to predict chemotherapeutic responses and prognosis for CC patients. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 14, 2024 Category: Cancer & Oncology Source Type: research
Application value of intraoperative electrophysiological monitoring in cerebral eloquent area glioma surgery: a retrospective cohort study
ConclusionsThe application of IONM could improve long-term neurological function, which is closely related to prognosis and can be used as an independent prognostic factor. IONM is practical and widely available for predicting postoperative functional deficits in patients with eloquent area glioma. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 13, 2024 Category: Cancer & Oncology Source Type: research
Identification of hub genes and diagnostic efficacy for triple-negative breast cancer through WGCNA and Mendelian randomization
ConclusionWe established a co-expression network using the WGCNA methodology to detect pivotal genes associated with TNBC. This finding holds promise for advancing the creation of pre-symptomatic diagnostic tools and deepening our comprehension of the pathogenic mechanisms involved in TNBC risk genes. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 12, 2024 Category: Cancer & Oncology Source Type: research
A combination of cuproptosis and lncRNAs predicts the prognosis and tumor immune microenvironment in cervical cancer
ConclusionIn conclusion, we constructed five cuprotosis-related lncRNA prognostic models, which may be new tumor therapeutic targets for the prevention and treatment of cervical cancer. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 12, 2024 Category: Cancer & Oncology Source Type: research
Diagnostic value of circulating tumor cells in patients with thyroid cancer: a retrospective study of 1478 patients
ConclusionsAs an emerging and noninvasive testing tool, the efficacy of CTCs in diagnosing thyroid cancer is limited. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 12, 2024 Category: Cancer & Oncology Source Type: research
Bilateral adrenal neuroblastoma: peculiar pattern of a rare pediatric presentation
ConclusionBSN treatment is similar to unilateral disease. A more conservative surgical approach with adrenal tissue preservation on less extensive side should be considered. Biological variables and extent of disease are amongst the most important prognostic determinants. Future studies are warranted to further address the biologic profiling of BSN and highlight prognostic significance of size difference between both adrenal sides. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 12, 2024 Category: Cancer & Oncology Source Type: research
DSCAM-AS1 promotes the development of prostate cancer
ConclusionDSCAM-AS1 is up-regulated in prostate cancer and regulates the progression of prostate cancer cells by targeting miR-338-3p. (Source: Hormones and Cancer)
Source: Hormones and Cancer - April 11, 2024 Category: Cancer & Oncology Source Type: research
