Visually Guided Uterine Biopsies in Physician ’s Office: Interview with Allison London Brown, CEO of LUMINELLE
LUMINELLE, a medtech company based in North Carolina, has developed a suite of endoscopic tools that allow clinicians to perform visually guided gynecological procedures right from their office. At present, the majority of uterine biopsies taken to investigate the cause of abnormal uterine bleeding are taken blind, with no visual guidance at all. This leads to suboptimal outcomes, and the frequent need to repeat the biopsy procedure because the first attempt did not yield an adequate sample.
To address this, LUMINELLE has developed the LUMINELLE SUSTAINE system and the LUMINELLE Bx (Biopsy) device. These technologies ar...
Source: Medgadget - August 4, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Exclusive Ob/Gyn Source Type: blogs
Underfunding Research Of Female Health Leaves Huge Amounts Of Money On The Table
“Did you know that at least one-third of women have lower back pain before their periods every month, and yet, nobody seems to fully understand why?” – asked a Medical Futurist team member a little while ago. The question led to a discussion about the differences in research, funding and understanding of male-only and female-only health issues, and consequently, to this article.
It is a well-known fact that some diseases or conditions dominantly affect one gender or the other. There are the trivial ones, like prostate cancer or ovarian, cervical, uterine cancers. But there is a long list of diseases and condit...
Source: The Medical Futurist - May 12, 2022 Category: Information Technology Authors: Andrea Koncz Tags: TMF Future of Medicine Healthcare Policy Medical Education women female health under-reseached gender gap in healthcare Source Type: blogs
Excitable Nanoparticles Destroy Endometriosis Lesions
Researchers at Oregon State University developed a nanoparticle system that can aid with the removal of endometrial lesions in a minimally invasive fashion. In endometriosis, endometrial tissue grows outside of the uterus, causing pain and affecting fertility. Surgery to remove these lesions is often unsuccessful and repeat surgeries are often required. The research team’s nanoparticle technology can aid in minimally invasively destroying such lesions.
The iron oxide nanoparticles can be delivered intravenously and are targeted to accumulate in endometrial lesions, and also handily act as an MRI contrast agent. By ap...
Source: Medgadget - April 25, 2022 Category: Medical Devices Authors: Conn Hastings Tags: Nanomedicine Ob/Gyn Radiology OregonState Source Type: blogs
Accelerating the Development of Tests for Endometriosis and Cancer
NIGMS’ Small Business Technology Transfer (STTR) program works toward more effective methods for patient screening, diagnosis, and treatment.
Translating lab discoveries into health care products requires large investments of time and resources. Through the STTR Regional Technology Transfer Accelerator Hubs for IDeA States program, NIGMS helps researchers interested in transitioning their discoveries and/or inventions into products. Here are the stories of three researchers working with the XLerator Hub, which funds projects in the southeastern United States and Puerto Rico.
Ending Diagnostic Delays for Endomet...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - April 7, 2021 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Injury and Illness Cancer Diseases Profiles Scientific Process Source Type: blogs
Fight Aging! Newsletter, February 15th 2021
This study assessed cancer risk associations for 3 recently developed methylation-based biomarkers of aging: PhenoAge, GrimAge, and predicted telomere length.
We observed relatively strong associations of age-adjusted PhenoAge with risk of colorectal, kidney, lung, mature B-cell, and urothelial cancers. Similar findings were obtained for age-adjusted GrimAge, but the association with lung cancer risk was much larger, after adjustment for smoking status, pack-years, starting age, time since quitting, and other cancer risk factors. Most associations appeared linear, larger than for the first-generation measures, and w...
Source: Fight Aging! - February 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, January 4th 2021
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - January 3, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A Look Back at 2020: Progress Towards the Treatment of Aging as a Medical Condition
While I suspect that COVID-19 will feature prominently in most retrospectives on 2020, I'll say only a little on it. The data on mortality by year end, if taken at face value, continues to suggest that the outcome will fall at the higher end of the early estimates of a pandemic three to six times worse than a bad influenza year, ten times worse than a normal influenza year. The people who die are near entirely the old, the co-morbid, and the immunocompromised. They die because they are suffering the damage and dysfunction of aging. Yet the societal conversation and the actions of policy makers ignore this.
There is ...
Source: Fight Aging! - December 31, 2020 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
Cancer Survivors Exhibit Greater Risk of New Cancers and Higher Mortality Due to those Cancers
The objective of this study is to quantify the overall and cancer type-specific risks of subsequent primary cancers (SPCs) among adult-onset cancer survivors by first primary cancer (FPC) types and sex. Among 1,537,101 survivors (mean age, 60.4 years; 48.8% women), 156,442 SPC cases and 88,818 SPC deaths occurred during 11,197,890 person-years of follow-up (mean, 7.3 years). Among men, the overall risk of developing any SPCs was statistically significantly higher for 18 of the 30 FPC types, and risk of dying from any SPCs was statistically significantly higher for 27 of 30 FPC types as compared with risks in the general po...
Source: Fight Aging! - December 29, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Fight Aging! Newsletter, November 9th 2020
In this study, young adult mice were submitted to endurance exercise training and the function, differentiation, and metabolic characteristics of satellite cells were investigated in vivo and in vitro.
We found that injured muscles from endurance-exercised mice display improved regenerative capacity, demonstrated through higher densities of newly formed myofibres compared with controls (evidenced by an increase in embryonic myosin heavy chain expression), as well as lower inflammation (evidenced by quantifying CD68-marked macrophages), and reduced fibrosis. Enhanced myogenic function was accompanied by an increased ...
Source: Fight Aging! - November 8, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Towards the Use of High Intensity Focused Ultrasound to More Precisely Destroy Tumor Tissue
Focused ultrasound is one of the many approaches used to directly kill cancer cells once they have grown to the point at which a tumor can be identified. It involves generating sufficient heat to kill cells, a fairly direct transfer of energy. Pruning back cancerous tissue is helpful, as tumors manipulate the signaling environment to subvert the immune system's ability to destroy cancerous cells, and constantly generate new mutations that ultimately lead to metastasis and the spread of a cancer throughout the body.
Removing tumor tissue in this way is not a cure, however. Curing cancer requires not just the removal ...
Source: Fight Aging! - November 3, 2020 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Reductio ad absurdum
The new Supreme Court nominee believes that a zygote -- the single cell that results from the merger of a sperm cell and an ovum -- is a human being just like you and your Aunt Fannie, and entitled to all of the rights, dignity and respect due accordingly. Can you guess what is wrong with this idea? As I have noted previously, it most certainly does not come from the Bible, not from the Old Testament or any saying ascribed to Jesus or Paul. Nobody actually knew what conception was until the 20th Century, actually, but people knew that pregnancy resulted from sexual intercourse and that it didn ' t become apparent unti...
Source: Stayin' Alive - October 1, 2020 Category: American Health Source Type: blogs
Obstetrics and Gynecology Needs Palliative Care
by Nathan Riley " Can you all, please, just leave us alone? "One particular experience with the death of a newborn stands out in my mind. Moments after birth the baby was breathless, and the neonatology team could not intubate. All of the kingdom ’s pediatric surgeons and other specialists rushed to labor and delivery to no avail. The baby was born with a four centimeter gap in his trachea, an irreparable condition. The mother sat there, holding her dying baby as he took his last breaths while physicians, nurses, and residents were busy as usual. Click-clacking away on computers. Adjusting blankets. Asking questions...
Source: Pallimed: A Hospice and Palliative Medicine Blog - September 24, 2020 Category: Palliative Care Tags: gynecology obstetrics palliative care pediatrics prenatal riley Source Type: blogs
My Infertility Journey as a Woman in Medicine
Editor’s Note: For more on the challenges as well as strategies to address physician infertility, please read this Academic Medicine Invited Commentary, cowritten by the author of this blog post.
Most of us in medicine pride ourselves on being organized, detail-oriented, conscientious and able to achieve excellent results with enough hard work—and are not used to failure and loss of control. My experience with infertility has been the first time that I truly experienced failure and complete loss of control, realizing that fertility is not a merit-based system. No matter how hard I try, how many doctors I cons...
Source: Academic Medicine Blog - March 11, 2020 Category: Universities & Medical Training Authors: Guest Author Tags: Featured Guest Perspective infertility physician well-being women in academic medicine Source Type: blogs
Renaissance Radiologists: Meet AJ Gunn, MD
AJ Gunn, M.D. graduated magna cum laude from Brigham Young University in Provo, UT, earning a BS in exercise physiology with a minor in sociology. He then returned home to South Dakota to attend medical school at the University of South Dakota. During medical school, he participated in the competitive Howard Hughes Medical Institute – National Institutes of Health Research Scholars Program and was awarded the Donald L. Alcott, M.D. Award for Clinical Promise. He graduated summa cum laude in 2009. He completed his diagnostic radiology residency at the Massachusetts General Hospital of Harvard Medical School in Boston, MA ...
Source: radRounds - February 21, 2020 Category: Radiology Authors: Robin Pine Miles Source Type: blogs
Renaissance Rad Feature: Meet AJ Gunn, MD
AJ Gunn, M.D. graduated magna cum laude from Brigham Young University in Provo, UT, earning a BS in exercise physiology with a minor in sociology. He then returned home to South Dakota to attend medical school at the University of South Dakota. During medical school, he participated in the competitive Howard Hughes Medical Institute – National Institutes of Health Research Scholars Program and was awarded the Donald L. Alcott, M.D. Award for Clinical Promise. He graduated summa cum laude in 2009. He completed his diagnostic radiology residency at the Massachusetts General Hospital of Harvard Medical School in Boston, MA ...
Source: radRounds - February 21, 2020 Category: Radiology Authors: Robin Pine Miles Source Type: blogs
