DR Congo, Ituri. Fleeing War, Weaving Life in IDP Camps of Bunia
The man reading is a displaced man in the IDP camp ISP in Bunia. Credit: Elena L. Pasquini By Elena L. PasquiniROME, Jul 29 2021 (IPS) He moves aside the curtain, thin as gauze, and then bends over. The darkness dazzles for a few seconds when one enters the house—actually, a den made of earth where air and light filter through the narrow entrance. Jean de Dieu Amani Paye holds her tiny baby, wrapped in an elegant fabric, in his arms. He was a teacher of French and Latin and had a small business. He also cultivated the land: cassava, corn, sorghum, and beans. Now he is a leader of the ISP camp on the outskirts of Bunia, ...
Source: IPS Inter Press Service - Health - July 29, 2021 Category: International Medicine & Public Health Authors: Elena Pasquini Tags: Africa Aid Armed Conflicts Crime & Justice Featured Gender Violence Headlines Health Human Rights Humanitarian Emergencies Migration & Refugees TerraViva United Nations Women's Health Source Type: news

Olympic gymnast Simone Biles steps away from competition, shines light on mental health
Olympian Simone Bile's decision to step away from competition and focus on her health is shining a light on mental health and athletes.... (Source: Reuters: Health)
Source: Reuters: Health - July 29, 2021 Category: Consumer Health News Source Type: news

FDA Approves Bylvay (odevixibat) for the Treatment of Pruritus in Patients with Progressive Familial Intrahepatic Cholestasis (PFIC)
BOSTON, July 20, 2021 (GLOBE NEWSWIRE) -- Albireo Pharma, Inc. (Nasdaq: ALBO), a rare liver disease company developing novel bile acid modulators, today announced U.S. Food& Drug Administration (FDA) approval of... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 20, 2021 Category: Drugs & Pharmacology Source Type: news

Why Richard Branson ’s Spaceflight Is a Very Big Deal
Depending on how you look at things, Richard Branson did not accomplish terribly much this morning. Yes, the billionaire co-founder of Virgin Galactic woke up intending to go to space today, and yes, he went. Along with two pilots and three other passengers, Branson lifted off aboard his VSS Unity spacecraft shortly before 9:00 a.m. MT, soared 86 km (53.5 miles) up, arced into space for four minutes of weightlessness and then glided gently back to Earth, landing on a runway in the Mojave Desert. Fine. Noted. But history will recall that the flight occurred more than 60 years after Alan Shepard flew the same popgun trajecto...
Source: TIME: Science - July 11, 2021 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized Source Type: news

‘Bowel Babe’ shares latest bowel cancer symptoms - 'A week ago my liver started to fail'
DEBORAH JAMES, better known as ‘Bowel Babe', has been living with stage four bowel cancer since she was diagnosed in December 2016. Last week she told her social media following an aggressive new tumour near her liver had wrapped itself around her bile duct. (Source: Daily Express - Health)
Source: Daily Express - Health - June 29, 2021 Category: Consumer Health News Source Type: news

Bile pulmonary embolism-related sudden death following an abdominal firearm injury: an autopsy case report and review of literature - Fnon NF, Seleim HM, Abdel-Wahab MS, Sobh ZK.
This article reports a fa... (Source: SafetyLit)
Source: SafetyLit - June 28, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation
In the adult liver, a population of facultative progenitor cells called biliary epithelial cells (BECs) proliferate and differentiate into cholangiocytes and hepatocytes after injury, thereby restoring liver function. In mammalian models of chronic liver injury, Notch signaling is essential for bile duct formation from these cells. However, the continual proliferation of BECs and differentiation of hepatocytes in these models have limited their use for determining whether Notch signaling is required for BECs to replenish hepatocytes after injury in the mammalian liver. Here, we used a temporally restricted model of hepatic...
Source: Signal Transduction Knowledge Environment - June 22, 2021 Category: Science Authors: Minnis-Lyons, S. E., Ferreira-Gonzalez, S., Aleksieva, N., Man, T. Y., Gadd, V. L., Williams, M. J., Guest, R. V., Lu, W.-Y., Dwyer, B. J., Jamieson, T., Nixon, C., Van Hul, N., Lemaigre, F. P., McCafferty, J., Leclercq, I. A., Sansom, O. J., Boulter, L., Tags: STKE Research Articles Source Type: news

Novel Drug Approved by FDA for Some Bile Duct Cancers Novel Drug Approved by FDA for Some Bile Duct Cancers
Infigratinib was approved for use in adults with previously treated unresectable bile duct cancer harboring an FGFR2 fusion or other rearrangement.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 2, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Changes in how cholesterol breaks down in the body may accelerate progression of dementia
(PLOS) The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimer's disease and vascular dementia. However, the underlying mechanisms mediating this relationship are poorly understood. A study published in the open-access journal PLOS Medicine by Vijay Varma and colleagues at the National Institute on Aging, suggests that disturbances in the conversion of cholesterol to bile acids may play a role in the development of dementia. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 27, 2021 Category: International Medicine & Public Health Source Type: news

A case report on fatal intoxication by tapentadol: study of distribution and metabolism - Carelli C, Freni F, Moretti M, Vignali C, Ballardini M, Morini L.
We report a case in which a tapentadol acute intoxication was suspected as the cause of death of a 39-year-old man: approximately two days after death, cardiac and femoral blood, as well as urine, bile, gastric content and chest hair, were collected during... (Source: SafetyLit)
Source: SafetyLit - May 20, 2021 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Norfolk and Norwich Hospital: 'Serious concerns' over three operations
The removal of a bile duct is one of three procedures by the same surgeon under investigation. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - April 27, 2021 Category: Consumer Health News Source Type: news

Crohn's disease may be caused by immune signaling failure
(Scripps Research Institute) Scientists find that T cells in the small intestine prevent bile acid-driven stress and inflammation. The work highlights a completely new direction in Crohn's disease research, and potentially, its treatment. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 7, 2021 Category: International Medicine & Public Health Source Type: news

Bile and Potatoes, 1921
One hundred years after its invention, BCG has stood the test of time as a vaccine against tuberculosis. (Source: The Scientist)
Source: The Scientist - April 1, 2021 Category: Science Tags: Foundations Magazine Issue Source Type: news

Europe Approves Pemigatinib for Bile Duct Cancer Europe Approves Pemigatinib for Bile Duct Cancer
The oral targeted therapy is for the treatment of locally advanced or metastatic cholangiocarcinoma.International Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - March 31, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Mirum Pharmaceuticals Announces FDA Acceptance of New Drug Application and Priority Review for Maralixibat in Alagille Syndrome
FOSTER CITY, Calif.--(BUSINESS WIRE)--Mar. 29, 2021-- Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) announced today that its New Drug Application (NDA) for maralixibat, an oral apical sodium dependent bile acid transporter (ASBT) inhibitor... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - March 29, 2021 Category: Drugs & Pharmacology Source Type: news