FDA Approves First Targeted Treatment for Patients with Cholangiocarcinoma, a Cancer of Bile Ducts
FDA has approved Pemazyre (pemigatinib), the first treatment approved for adults with certain types of previously treated, advanced cholangiocarcinoma, a rare form of cancer that forms in bile ducts. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - April 17, 2020 Category: Drugs & Pharmacology Authors: FDA Source Type: news
' Minor' Iatrogenic Bile Duct Injuries Can Have Major Consequences'Minor' Iatrogenic Bile Duct Injuries Can Have Major Consequences
Bile duct injuries that are considered ' minor, ' that is, those of Strasberg grades A to D, can nonetheless result in substantial long-term morbidity and costs, according to a new study from the UK.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - April 17, 2020 Category: Surgery Tags: General Surgery News Source Type: news
Ludwig MSK study reveals bile metabolite of gut microbes boosts immune cells
(Ludwig Institute for Cancer Research) A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 15, 2020 Category: International Medicine & Public Health Source Type: news
Drug used for liver disease also affects C. diff life cycle, reduces inflammation in mice
(North Carolina State University) Researchers have found that a commonly used drug made from secondary bile acids can affect the life cycle of Clostridioides difficile (C. diff) in vitro and reduce the inflammatory response to C. diff in mice. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - March 30, 2020 Category: Biology Source Type: news
Chinese vs. Western Governance: The case of COVID-19
Emergency room nurses wear face masks at Second People's Hospital of Shenzhen in China. Credit: Man Yi/ UN News By Martin JacquesLONDON, Mar 26 2020 (IPS) During January the onslaught in the Western media, notably the US and the UK, against the Chinese government’s handling of the Covid-19 epidemic, was merciless. The Chinese government stood accused of an inhumane attitude towards its people, secrecy, a cover-up, and an overwhelming concern for its own survival above all other considerations.
The actual evidence was thin bordering at times on the threadbare but this made little difference to the venom and bile of the as...
Source: IPS Inter Press Service - Health - March 26, 2020 Category: International Medicine & Public Health Authors: Martin Jacques Tags: Democracy Global Headlines Health Coronavirus Source Type: news
Bile duct cancer: Mayo Clinic Radio Health Minute
In this Mayo Clinic Radio Health Minute, Dr. Bret Petersen, a Mayo Clinic?gastroenterologist, discusses bile duct cancer. To listen, click the link below. Bile duct cancer (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - March 19, 2020 Category: Databases & Libraries Source Type: news
Gravely ill mother diagnosed with bile duct cancer gets new lease of life from revolutionary drug
Mother-of-four Kadiatou Diallo, who is originally from Guinea in West Africa and has lived in the UK for nearly 20 years, is feeling better than she has done in years as a result of taking the new drug. (Source: the Mail online | Health)
Source: the Mail online | Health - March 14, 2020 Category: Consumer Health News Source Type: news
The incidence of drugs in fatally injured drivers - Woodhouse EJ.
Methods for the collection of blood, urine, bile and alcohol washes of face and fingers from fatally injured drivers have been developed. Specimens were supplied by coroners and medical examiners from fatally injured drivers. Seven hundred and ten were ret... (Source: SafetyLit)
Source: SafetyLit - February 29, 2020 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
New bile discovery will rewrite textbooks
(Michigan State University) Forget what you know about bile because that's about to change, thanks to a new discovery made by Michigan State University and published in the current issue of Nature. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - February 26, 2020 Category: Biology Source Type: news
Ulcerative colitis: bacteria findings raise hopes for new treatment
Sufferers found to have low levels of gut microbes that convert bile acids into other substancesHopes of developing a new treatment for ulcerative colitis have been raised by research suggesting the condition may be linked to low levels of certain bacteria in the gut.Ulcerative colitis is a long-term condition in whichthe colon becomes inflamed. Accordingto the NHS, it is thought to be an autoimmune disease and affects one in every 420 people in the UK. Sufferers need to empty their bowels frequently, develop ulcers in their colon and have recurring bouts of diarrhoea with blood and pus in the faeces.Continue reading... (S...
Source: Guardian Unlimited Science - February 25, 2020 Category: Science Authors: Nicola Davis Tags: Digestive disorders Science Health & wellbeing Life and style Society Source Type: news
Bile duct cancer treatment potential boost from tailored medication -- study
(University of Birmingham) Treatment of patients suffering from bile duct cancer could be improved by tailoring medication to the levels of a key protein in people with the disease, according to new research. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 14, 2020 Category: Cancer & Oncology Source Type: news
'Genetic rewiring' drives cancer's drug resistance
(Institute of Cancer Research) Tiny RNA molecule rewires signalling network in bile duct cancer. Drugs to block RNA could overcome cancer's drug resistance. Findings announced to coincide with Bile Duct Cancer Awareness Day. Results could be applicable in other cancer types and have wider benefit. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - February 11, 2020 Category: Cancer & Oncology Source Type: news
Wild melancholy: on the historical plausibility of a black bile theory of blood madness, or h æmatomania - Verplaetse J.
Nineteenth-century art historian John Addington Symonds coined the term h æmatomania (blood madness) for the extremely bloodthirsty behaviour of a number of disturbed rulers like Ibrahim II of Ifriqiya (850-902) and Ezzelino da Romano (1194-1259). A... (Source: SafetyLit)
Source: SafetyLit - January 27, 2020 Category: International Medicine & Public Health Tags: Commentary Source Type: news
Study suggests new strategy for treating advanced, progressing bile duct cancer
(Ohio State University Wexner Medical Center) A new study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) shows how resistance to a promising targeted drug develops in patients with a rare, lethal cancer of the bile ducts called cholangiocarcinoma. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - January 14, 2020 Category: Cancer & Oncology Source Type: news
Epistane, an anabolic steroid used for recreational purposes, causes cholestasis with elevated levels of cholic acid conjugates, by upregulating bile acid synthesis (CYP8B1) and cross-talking with nuclear receptors in human hepatocytes - Petrov PD, Fern ández-Murga L, Conde I, Martínez-Sena T, Guzmán C, Castell JV, Jover R.
Anabolic-androgenic steroids are testosterone derivatives, used by body-builders to increase muscle mass. Epistane (EPI) is an orally administered 17 α-alkylated testosterone derivative with 2a-3a epithio ring. We identified four individuals who, after EPI... (Source: SafetyLit)
Source: SafetyLit - January 4, 2020 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
