Novel Non-Bile FXR Agonist Promising in PBC Patients
(MedPage Today) -- Phase II trial interim analysis found dose-dependent response, good safety profile (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 16, 2018 Category: Gastroenterology Source Type: news
First-in-human clinical trial of new targeted therapy drug reports promising responses for multiple
(University of Texas M. D. Anderson Cancer Center) A phase I, first-in-human study led by The University of Texas MD Anderson Cancer Center reveals for the first time, an investigational drug that is effective and safe for patients with cancers caused by an alteration in the receptor tyrosine kinase known as RET. The drug appears to be promising as a potential therapy for RET-driven cancers, such as medullary and papillary thyroid, non-small cell lung, colorectal and bile duct cancers, which have been historically difficult to treat. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 15, 2018 Category: Cancer & Oncology Source Type: news
The Medical Device Behind the Discovery of a New Human Structure
What on Earth is this thing? That is the question David Carr-Locke, MD, and his colleagues asked when they discovered a microanatomical network of interconnected spaces, filled with fluid and lined by collagen with a unique arrangement, that appears to be present throughout the body.
Whether or not this network is actually a newly discovered human organ is debatable. What is clear, however, is that this discovery is very widespread throughout the body and contains a lot of fluid, said Carr-Locke, clinical director of the Center for Advanced Digestive Care at Weill Cornell Medical College and New York Presbyterian Hospita...
Source: MDDI - April 13, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Imaging Source Type: news
How Intestinal Bacteria Affects Blood Sugar and Lipid Levels
Influence of changes in intestinal bacteria on sugar and lipid metabolism finds secondary bile acids produced by the bacteria can influence blood glucose and lipid concentrations and parts of their molecular mechanisms (Source: Disabled World)
Source: Disabled World - April 10, 2018 Category: Disability Tags: Digestive Disorders Source Type: news
Duodenum May Help Fight Metabolic Disease (CME/CE)
(MedPage Today) -- Manipulating duodenal features from bile acids to neurons may offer new insight into obesity and type 2 diabetes (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - April 6, 2018 Category: Cardiology Source Type: news
Scientists Have Discovered a New Organ in the Human Body
It’s not a second stomach or a mini-brain. But scientists have discovered an important new organ that may play a critical role in how many tissues and other organs do their jobs, as well as in some diseases like cancer.
In a study published in Scientific Reports, a New York University-led team of researchers describe the interstitium, which is a series of connected, fluid-filled spaces found under skin as well as throughout the gut, lungs, blood vessels and muscles.
The bubble wrap-like network only became visible when the pathologists used a new laser endoscope, called a confocal laser endomicroscope, that allowed ...
Source: TIME: Health - March 27, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized health healthytime medicine Source Type: news
Scientists Have Discovered a New Organ in the Human Body. What is the Interstitium?
It’s not a second stomach or a mini-brain. But scientists have discovered an important new organ that may play a critical role in how many tissues and other organs do their jobs, as well as in some diseases like cancer.
In a study published in Scientific Reports, a New York University-led team of researchers describe the interstitium, which is a series of connected, fluid-filled spaces found under skin as well as throughout the gut, lungs, blood vessels and muscles.
The bubble wrap-like network only became visible when the pathologists used a new laser endoscope, called a confocal laser endomicroscope, that allowed ...
Source: TIME: Health - March 27, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized health healthytime medicine Source Type: news
Fitness Trackers, Virtual Coaching Helps Patients Stay Fit After Cardiac Rehab
Treatment TermsCardiac prevention and cardiac rehabilitation
Author
Sarah Avery
Overview
Heart patients typically do well during cardiac rehab programs but tend to lose momentum once the formal gym-based regimens end. Duke Health researchers wanted to know if something could be done to change that result. Their small study found a follow-up program that uses wearable fitness trackers and virtual sessions with a health coach helped heart patients sustain lifestyle improvements after their cardiac rehab program ended.
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Mobile Health Helps Maintain Fitness Gains
Content" The benefits of a ...
Source: dukehealth.org: Duke Health News - March 19, 2018 Category: Consumer Health News Authors: efh7 at duke.edu Source Type: news
Redirecting the flow of bile to the distal small intestine could provide metabolic health benefits similar to bariatric surgery
Study suggests surgical diversion of bile to the ileum results in many of the health benefits of RYGB, without the risks linked to dramatic GI tract changes. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
Plant toxins linked to biliary atresia in newborn animals
Plant toxin causes changes that resemble biliary atresia, a liver disease that affects newborns and causes the bile ducts to become inflamed and scarred. (Source: NIDDK News)
Source: NIDDK News - March 15, 2018 Category: Endocrinology Source Type: news
FDA Cracks Down on Duodenoscope Manufacturers Again
FDA doesn't like it when manufacturers ignore the agency's orders, as all three companies that make duodenoscope should probably have figured out by now. The company said it issued warning letters Friday to Olmpus, Pentax, and Fujifilm for failing to comply with post-market surveillance requirements to assess the effectiveness of reprocessing the devices.
As part of an ongoing effort to prevent patient infections associated with the transmission of bacteria from contaminated duodenoscopes, FDA in 2015 ordered these manufacturers to conduct a post-market surveillance study to determine whether healthcare facilities were abl...
Source: MDDI - March 10, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Regulatory and Compliance Source Type: news
Liver study offers insights into hard-to-treat diseases
(University of Edinburgh) A key cell process that could cause damage to bile ducts and help explain some liver diseases has been identified by scientists. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 9, 2018 Category: International Medicine & Public Health Source Type: news
Polyganics liver and pancreas sealant wins FDA breakthrough designation
Polyganics said today it won FDA breakthrough device designation for its Liver and Pancreas Sealant Patch designed to prevent fluid leakage after hepato-pancreato-biliary procedures.
The Dutch company’s Liver and Pancreas Sealant Patch is made from a proprietary bioresorbable polymer designed to seal-off the surgically treated tissue during the critical healing period.
“There is a clear need for a device that can effectively control the leakage of fluids in HPB surgery, that can be applied easily and can seal and withstand the enzymatic action and acid substances such as bile and pancreatic fluids. If an effec...
Source: Mass Device - March 8, 2018 Category: Medical Devices Authors: Fink Densford Tags: Food & Drug Administration (FDA) Regulatory/Compliance Surgical Wound Care Polyganics Source Type: news
Building better bile ducts
(Source: ScienceNOW)
Source: ScienceNOW - March 8, 2018 Category: Science Authors: Sampaziotis, F. Tags: essays Source Type: news
Boston Sci Whets M & amp;A Appetite with EMcision Buy
Boston Scientific could be very busy with M&A this year. During the Marlborough, MA-based company’s most recent earnings call, CEO Michael Mahoney hinted at the possibility of potential acquisitions.
“We do have a pretty active M&A appetite,” Mahoney said, according to a transcript from Seeking Alpha. "So, I think you'll see us be active with tuck-in acquisitions to strengthen our category leadership strategy."
On Monday, Boston Scientific backed up its CEO’s words and revealed it would strengthen its endoscopy offerings with the acquisition of London – based EMcision, for an undisclosed sum.
With the EM...
Source: MDDI - March 5, 2018 Category: Medical Devices Authors: Omar Ford Tags: Medical Device Business Source Type: news
