Dey Laboratory Research Finds Bile Acids Affect Gut Motility and the Human Microbiome, Insights That May Lead to New Clinical Laboratory Tests
These new findings may affect how microbiology labs and physicians diagnose and treat several gastrointestinal conditions Once again, a research effort has teased out new insights into the role the human microbiome plays in our digestive processes. Microbiologist and medical laboratory managers will be interested to learn that, according to the study team, specific microbes […] The post Dey Laboratory Research Finds Bile Acids Affect Gut Motility and the Human Microbiome, Insights That May Lead to New Clinical Laboratory Tests appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - September 3, 2021 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Digital Pathology International Laboratory News Laboratory Pathology Laboratory Testing Molecular Diagnostics, Genetic Testing, Whole Gene Sequencing Precision Medicine anatomic pathology bile acid bile salt hydrolase blue poop challenge Source Type: news

Gut Bugs May Help Centenarians Reach Their 100th Birthdays
Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness. (Source: The Scientist)
Source: The Scientist - August 30, 2021 Category: Science Tags: Sponsored Article Source Type: news

What are Some of the Complications of Short Bowel Syndrome?
Discussion Necrotizing enterocolitis (NEC) is one of the most common gastrointestinal emergencies in neonates. Mortality rates are from 0-45% depending on infant weight and gestation with more premature and smaller infants having greater mortality. NEC usually occurs in premature infants but it also occurs in term infants. The etiology is unknown but is probably multifactorial with ischemia and/or reperfusion playing some role. There are ‘outbreaks’ of NEC but no causative organism has been identified. Regardless of the originating cause, inflammation of the intestine and release of inflammatory mediators causes variou...
Source: PediatricEducation.org - August 30, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

FDA Approves Ivosidenib for Bile Duct Cancer FDA Approves Ivosidenib for Bile Duct Cancer
Ivosidenib is the first targeted therapy approved for the treatment of IDH1-mutated cholangiocarcinomaFDA Approvals (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 26, 2021 Category: Gastroenterology Tags: Hematology-Oncology News Alert Source Type: news

What Does It Mean When You Throw Up Bile?
Title: What Does It Mean When You Throw Up Bile?Category: Diseases and ConditionsCreated: 8/23/2021 12:00:00 AMLast Editorial Review: 8/23/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 23, 2021 Category: Nutrition Source Type: news

What can help ease my bile reflux symptoms? DR MARTIN SCURR answers your health questions
DR MARTIN SCURR: Constant nausea can be deeply unpleasant and debilitating, and I think it's better to tackle this than worry about the potential side-effects of your medication. (Source: the Mail online | Health)
Source: the Mail online | Health - August 17, 2021 Category: Consumer Health News Source Type: news

DR Congo, Ituri. Fleeing War, Weaving Life in IDP Camps of Bunia
The man reading is a displaced man in the IDP camp ISP in Bunia. Credit: Elena L. Pasquini By Elena L. PasquiniROME, Jul 29 2021 (IPS) He moves aside the curtain, thin as gauze, and then bends over. The darkness dazzles for a few seconds when one enters the house—actually, a den made of earth where air and light filter through the narrow entrance. Jean de Dieu Amani Paye holds her tiny baby, wrapped in an elegant fabric, in his arms. He was a teacher of French and Latin and had a small business. He also cultivated the land: cassava, corn, sorghum, and beans. Now he is a leader of the ISP camp on the outskirts of Bunia, ...
Source: IPS Inter Press Service - Health - July 29, 2021 Category: International Medicine & Public Health Authors: Elena Pasquini Tags: Africa Aid Armed Conflicts Crime & Justice Featured Gender Violence Headlines Health Human Rights Humanitarian Emergencies Migration & Refugees TerraViva United Nations Women's Health Source Type: news

Olympic gymnast Simone Biles steps away from competition, shines light on mental health
Olympian Simone Bile's decision to step away from competition and focus on her health is shining a light on mental health and athletes.... (Source: Reuters: Health)
Source: Reuters: Health - July 29, 2021 Category: Consumer Health News Source Type: news

FDA Approves Bylvay (odevixibat) for the Treatment of Pruritus in Patients with Progressive Familial Intrahepatic Cholestasis (PFIC)
BOSTON, July 20, 2021 (GLOBE NEWSWIRE) -- Albireo Pharma, Inc. (Nasdaq: ALBO), a rare liver disease company developing novel bile acid modulators, today announced U.S. Food& Drug Administration (FDA) approval of... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - July 20, 2021 Category: Drugs & Pharmacology Source Type: news

Why Richard Branson ’s Spaceflight Is a Very Big Deal
Depending on how you look at things, Richard Branson did not accomplish terribly much this morning. Yes, the billionaire co-founder of Virgin Galactic woke up intending to go to space today, and yes, he went. Along with two pilots and three other passengers, Branson lifted off aboard his VSS Unity spacecraft shortly before 9:00 a.m. MT, soared 86 km (53.5 miles) up, arced into space for four minutes of weightlessness and then glided gently back to Earth, landing on a runway in the Mojave Desert. Fine. Noted. But history will recall that the flight occurred more than 60 years after Alan Shepard flew the same popgun trajecto...
Source: TIME: Science - July 11, 2021 Category: Science Authors: Jeffrey Kluger Tags: Uncategorized Source Type: news

‘Bowel Babe’ shares latest bowel cancer symptoms - 'A week ago my liver started to fail'
DEBORAH JAMES, better known as ‘Bowel Babe', has been living with stage four bowel cancer since she was diagnosed in December 2016. Last week she told her social media following an aggressive new tumour near her liver had wrapped itself around her bile duct. (Source: Daily Express - Health)
Source: Daily Express - Health - June 29, 2021 Category: Consumer Health News Source Type: news

Bile pulmonary embolism-related sudden death following an abdominal firearm injury: an autopsy case report and review of literature - Fnon NF, Seleim HM, Abdel-Wahab MS, Sobh ZK.
This article reports a fa... (Source: SafetyLit)
Source: SafetyLit - June 28, 2021 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Notch-IGF1 signaling during liver regeneration drives biliary epithelial cell expansion and inhibits hepatocyte differentiation
In the adult liver, a population of facultative progenitor cells called biliary epithelial cells (BECs) proliferate and differentiate into cholangiocytes and hepatocytes after injury, thereby restoring liver function. In mammalian models of chronic liver injury, Notch signaling is essential for bile duct formation from these cells. However, the continual proliferation of BECs and differentiation of hepatocytes in these models have limited their use for determining whether Notch signaling is required for BECs to replenish hepatocytes after injury in the mammalian liver. Here, we used a temporally restricted model of hepatic...
Source: Signal Transduction Knowledge Environment - June 22, 2021 Category: Science Authors: Minnis-Lyons, S. E., Ferreira-Gonzalez, S., Aleksieva, N., Man, T. Y., Gadd, V. L., Williams, M. J., Guest, R. V., Lu, W.-Y., Dwyer, B. J., Jamieson, T., Nixon, C., Van Hul, N., Lemaigre, F. P., McCafferty, J., Leclercq, I. A., Sansom, O. J., Boulter, L., Tags: STKE Research Articles Source Type: news

Novel Drug Approved by FDA for Some Bile Duct Cancers Novel Drug Approved by FDA for Some Bile Duct Cancers
Infigratinib was approved for use in adults with previously treated unresectable bile duct cancer harboring an FGFR2 fusion or other rearrangement.FDA Approvals (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - June 2, 2021 Category: Cancer & Oncology Tags: Hematology-Oncology News Alert Source Type: news

Changes in how cholesterol breaks down in the body may accelerate progression of dementia
(PLOS) The blood-brain barrier is impermeable to cholesterol, yet high blood cholesterol is associated with increased risk of Alzheimer's disease and vascular dementia. However, the underlying mechanisms mediating this relationship are poorly understood. A study published in the open-access journal PLOS Medicine by Vijay Varma and colleagues at the National Institute on Aging, suggests that disturbances in the conversion of cholesterol to bile acids may play a role in the development of dementia. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - May 27, 2021 Category: International Medicine & Public Health Source Type: news