Mayo Clinic Q & amp;A podcast: Hidden gallbladder and bile duct cancers
The gallbladder is a small, pear-shaped organ that sits just beneath the liver, on the right side of the abdomen. Slender tubes that carry bile fluid also are also located in that area. Because of the relatively hidden nature of the gallbladder and bile ducts, cancers can grow without being detected. Late detection can mean [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 22, 2021 Category: Databases & Libraries Source Type: news
Lab-grown ‘mini-bile ducts’ by scientists at Cambridge university used to repair human livers in regenerative medicine first
Scientists have used a technique to grow bile duct organoids – often referred to as ‘mini-organs’ – in the lab and shown that these can... (Source: Reuters: Health)
Source: Reuters: Health - February 20, 2021 Category: Consumer Health News Source Type: news
Organoids Repair Bile Ducts
Researchers determined that when introduced into damaged mouse or donated human livers, these lab-grown tissues could integrate into bile ducts and function normally. (Source: The Scientist)
Source: The Scientist - February 18, 2021 Category: Science Tags: News & Opinion Source Type: news
Organoids regenerate human bile ducts
(Source: ScienceNOW)
Source: ScienceNOW - February 18, 2021 Category: Science Authors: Kelly, P. N. Tags: Cell Biology, Medicine, Diseases twis Source Type: news
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver
Organoid technology holds great promise for regenerative medicine but has not yet been applied to humans. We address this challenge using cholangiocyte organoids in the context of cholangiopathies, which represent a key reason for liver transplantation. Using single-cell RNA sequencing, we show that primary human cholangiocytes display transcriptional diversity that is lost in organoid culture. However, cholangiocyte organoids remain plastic and resume their in vivo signatures when transplanted back in the biliary tree. We then utilize a model of cell engraftment in human livers undergoing ex vivo normothermic perfusion to...
Source: ScienceNOW - February 18, 2021 Category: Science Authors: Sampaziotis, F., Muraro, D., Tysoe, O. C., Sawiak, S., Beach, T. E., Godfrey, E. M., Upponi, S. S., Brevini, T., Wesley, B. T., Garcia-Bernardo, J., Mahbubani, K., Canu, G., Gieseck, R., Berntsen, N. L., Mulcahy, V. L., Crick, K., Fear, C., Robinson, S., Tags: Cell Biology, Medicine, Diseases reports Source Type: news
Know the Signs of Rare But Deadly Gall Bladder, Bile Duct Cancers
(Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - February 16, 2021 Category: Cancer & Oncology Tags: Gastroenterology, Hepatology, Oncology, News, Source Type: news
Know the Signs of Rare But Deadly Gall Bladder, Bile Duct Cancers
TUESDAY, Feb. 16, 2021 -- Most people aren ' t aware of the signs of gallbladder or bile duct cancer, but the Rutgers Cancer Institute of New Jersey says they should be.
The gallbladder is a small organ connected to the liver by bile ducts. Its job... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 16, 2021 Category: General Medicine Source Type: news
Know the Signs of Rare But Deadly Gall Bladder, Bile Duct Cancers
Title: Know the Signs of Rare But Deadly Gall Bladder, Bile Duct CancersCategory: Health NewsCreated: 2/16/2021 12:00:00 AMLast Editorial Review: 2/16/2021 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - February 16, 2021 Category: Cancer & Oncology Source Type: news
Pandemic-Related Delays in Removing Intraductal Bile Duct Stents Can Be Harmful Pandemic-Related Delays in Removing Intraductal Bile Duct Stents Can Be Harmful
Priority should be given to timely removal of stents following recovery in patients who undergo endoscopic retrograde cholangiopancreatography with biliary stent placement, according to UK researchers.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - February 12, 2021 Category: Gastroenterology Tags: Gastroenterology News Source Type: news
What Is the Function of Bile?
Title: What Is the Function of Bile?Category: Diseases and ConditionsCreated: 2/2/2021 12:00:00 AMLast Editorial Review: 2/2/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - February 2, 2021 Category: Nutrition Source Type: news
Bile acids may play previously unknown role in Parkinson's
(Van Andel Research Institute) What does bile acid production in the digestive tract have to do with Parkinson's disease? Quite a lot, according to a sweeping new analysis published in the journal Metabolites. The findings reveal that changes in the gut microbiome -- the rich population of helpful microbes that call the digestive tract home -- may in turn alter bile acid production by favoring synthesis of toxic forms of the acids. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - February 2, 2021 Category: International Medicine & Public Health Source Type: news
Elobixibat: A Novel Treatment for Chronic Constipation Elobixibat: A Novel Treatment for Chronic Constipation
Elobixibat, a novel ileal bile acid transport inhibitor, appears to be a safe and effective treatment for chronic constipation.Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 27, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Albireo Announces U.S. FDA Acceptance of New Drug Application for Odevixibat
BOSTON, Jan. 25, 2021 (GLOBE NEWSWIRE) -- Albireo Pharma, Inc. (Nasdaq: ALBO), a clinical-stage rare liver disease company developing novel bile acid modulators, today announced that the U.S. Food and Drug... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - January 25, 2021 Category: Drugs & Pharmacology Source Type: news
What Is the Common Bile Duct
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - January 11, 2021 Category: General Medicine Source Type: news
Albireo Submits for U.S. FDA and EMA Product Approval of Once-Daily Odevixibat for PFIC
BOSTON, Dec. 08, 2020 (GLOBE NEWSWIRE) -- Albireo Pharma, Inc. (Nasdaq: ALBO), a clinical-stage rare liver disease company developing novel bile acid modulators, today announced it has submitted a New Drug Application (NDA) to... (Source: Drugs.com - New Drug Applications)
Source: Drugs.com - New Drug Applications - December 8, 2020 Category: Drugs & Pharmacology Source Type: news
