In Patients With CBD Stones, Cholecystectomy Wound Infection Rates Similar With Broad- vs Narrow-Spectrum Antibiotics In Patients With CBD Stones, Cholecystectomy Wound Infection Rates Similar With Broad- vs Narrow-Spectrum Antibiotics
In patients with common bile duct stones undergoing same-admission cholecystectomy, surgical site infection rates are low and similar with broad- and narrow-spectrum antibiotics, observational data suggest.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - May 19, 2022 Category: Gastroenterology Tags: General Surgery News Source Type: news

HAIP Chemotherapy or Resection for Multifocal Bile Duct Cancer?
(MedPage Today) -- Hepatic arterial infusion pump (HAIP) floxuridine chemotherapy may represent an effective alternative to curative-intent resection in patients with multifocal intrahepatic cholangiocarcinoma who are at risk for surgical complications... (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - May 11, 2022 Category: Surgery Source Type: news

The Many Roles of Cholesterol in Sepsis: A Review
The biological functions of cholesterol are diverse, ranging from cell membrane integrity, cell membrane signaling, and immunity to the synthesis of steroid and sex hormones, vitamin D, bile acids, and oxysterols. Multiple studies have demonstrated hypocholesterolemia in sepsis, the degree of which is an excellent prognosticator of poor outcomes. However, the clinical significance of hypocholesterolemia has been largely unrecognized. We undertook a detailed review of the biological roles of cholesterol, the impact of sepsis, its reliability as a prognosticator in sepsis, and the potential utility of cholesterol as a treatm...
Source: Current Awareness Service for Health (CASH) - April 13, 2022 Category: Consumer Health News Source Type: news

Association Between Circulating Bile Acid Alterations and NASH Association Between Circulating Bile Acid Alterations and NASH
This study aimed to elucidate alterations in bile acid metabolism according to NAFLD severity, in the absence of obesity.Liver International (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 31, 2022 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Greater Intestinal Permeability Seen With Bile Acid Diarrhea Than IBS Diarrhea Greater Intestinal Permeability Seen With Bile Acid Diarrhea Than IBS Diarrhea
People with bile acid diarrhea may have more permeable intestines than people with irritable bowel syndrome diarrhea, a new study suggests.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - January 3, 2022 Category: Gastroenterology Tags: Gastroenterology News Source Type: news

Neonatal Cholestasis: Updates on Diagnostics, Therapeutics, and Prevention
Cholestatic jaundice is a common presenting feature of hepatobiliary and/or metabolic dysfunction in the newborn and young infant. Timely detection of cholestasis, followed by rapid step-wise evaluation to determine the etiology, is crucial to identify those causes that are amenable to medical or surgical intervention and to optimize outcomes for all infants. In the past 2 decades, genetic etiologies have been elucidated for many cholestatic diseases, and next-generation sequencing, whole-exome sequencing, and whole-genome sequencing now allow for relatively rapid and cost-effective diagnosis of conditions not previously i...
Source: NeoReviews recent issues - December 1, 2021 Category: Pediatrics Source Type: news

Science Saturday: Regenerative technology uncovers new discoveries in liver disease
Mayo Clinic researchers have developed a method for generating bile duct cells from stem cells. This technology enables them to study important aspects of primary sclerosing cholangitis, a rare bile duct disease that often destroys the liver. Using these regenerative technologies, Robert Huebert, M.D., and Nidhi Jalan Sakrikar, Ph.D., also confirmed that primary sclerosing cholangitis has links to cellular senescence, a feature of aging cells. This research lays the foundation for additional disease modeling to better understand progression of a complex… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 20, 2021 Category: Databases & Libraries Source Type: news

KRAS-Variant Subtypes Tied to Worse Outcomes in Intrahepatic Bile Duct Cancer KRAS-Variant Subtypes Tied to Worse Outcomes in Intrahepatic Bile Duct Cancer
In patients with intrahepatic cholangiocarcinoma who underwent curative resection, G12 KRAS variants, were associated with worse survival and increased risk of recurrence in a Chinese cohort study.Reuters Health Information (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - November 19, 2021 Category: Gastroenterology Tags: Hematology-Oncology News Source Type: news

Consumer Health: What do you know about liver cancer?
October is Liver Cancer Awareness Month, which makes this a good time to learn more about liver cancer. More than 42,000 new cases of primary liver cancer and intrahepatic bile duct cancer will be diagnosed in the U.S. this year, and more than 30,000 people will die of these diseases, according to the American Cancer Society. Liver cancer is cancer that begins in the cells of your liver, which is a football-sized organ in the upper… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 7, 2021 Category: Databases & Libraries Source Type: news

Duodenogastroesophageal Reflux Prevalence and Treatment Duodenogastroesophageal Reflux Prevalence and Treatment
How prevalent is duodenogastroesophageal, or"bile", reflux, and what is its impact on GERD symptoms and esophageal lesions?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 4, 2021 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news

Dey Laboratory Research Finds Bile Acids Affect Gut Motility and the Human Microbiome, Insights That May Lead to New Clinical Laboratory Tests
These new findings may affect how microbiology labs and physicians diagnose and treat several gastrointestinal conditions Once again, a research effort has teased out new insights into the role the human microbiome plays in our digestive processes. Microbiologist and medical laboratory managers will be interested to learn that, according to the study team, specific microbes […] The post Dey Laboratory Research Finds Bile Acids Affect Gut Motility and the Human Microbiome, Insights That May Lead to New Clinical Laboratory Tests appeared first on Dark Daily. (Source: Dark Daily)
Source: Dark Daily - September 3, 2021 Category: Laboratory Medicine Authors: Jillia Schlingman Tags: Digital Pathology International Laboratory News Laboratory Pathology Laboratory Testing Molecular Diagnostics, Genetic Testing, Whole Gene Sequencing Precision Medicine anatomic pathology bile acid bile salt hydrolase blue poop challenge Source Type: news

Gut Bugs May Help Centenarians Reach Their 100th Birthdays
Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness. (Source: The Scientist)
Source: The Scientist - August 30, 2021 Category: Science Tags: Sponsored Article Source Type: news

What are Some of the Complications of Short Bowel Syndrome?
Discussion Necrotizing enterocolitis (NEC) is one of the most common gastrointestinal emergencies in neonates. Mortality rates are from 0-45% depending on infant weight and gestation with more premature and smaller infants having greater mortality. NEC usually occurs in premature infants but it also occurs in term infants. The etiology is unknown but is probably multifactorial with ischemia and/or reperfusion playing some role. There are ‘outbreaks’ of NEC but no causative organism has been identified. Regardless of the originating cause, inflammation of the intestine and release of inflammatory mediators causes variou...
Source: PediatricEducation.org - August 30, 2021 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

FDA Approves Ivosidenib for Bile Duct Cancer FDA Approves Ivosidenib for Bile Duct Cancer
Ivosidenib is the first targeted therapy approved for the treatment of IDH1-mutated cholangiocarcinomaFDA Approvals (Source: Medscape Gastroenterology Headlines)
Source: Medscape Gastroenterology Headlines - August 26, 2021 Category: Gastroenterology Tags: Hematology-Oncology News Alert Source Type: news

What Does It Mean When You Throw Up Bile?
Title: What Does It Mean When You Throw Up Bile?Category: Diseases and ConditionsCreated: 8/23/2021 12:00:00 AMLast Editorial Review: 8/23/2021 12:00:00 AM (Source: MedicineNet Digestion General)
Source: MedicineNet Digestion General - August 23, 2021 Category: Nutrition Source Type: news