Is the 100-year old TB vaccine a new weapon against Alzheimer ’s?
Studies suggest the BCG jab discovered a century ago could provide a cheap and effective way of boosting the immune system to protect people from developing the conditionScientific discoveries can emerge from the strangest places. In early 1900s France, the doctor Albert Calmette and the veterinarian Camille Gu érin aimed to discover how bovine tuberculosis was transmitted. To do so, they first had to find a way of cultivating the bacteria. Sliced potatoes – cooked with ox bile and glycerine – proved to be the perfect medium.As the bacteria grew, however, Calmette and Gu érin were surprised to find thateach generatio...
Source: Guardian Unlimited Science - February 25, 2024 Category: Science Authors: David Robson Tags: Alzheimer's Immunology Science Society Health Medical research Biochemistry and molecular biology Tuberculosis Vaccines and immunisation Dementia Source Type: news

Doctor shares breakfast he eats every day that can lower cholesterol naturally
A creamy food packed with fibre could help bind bile acids which will decrease high cholesterol in your body naturally. (Source: Daily Express - Health)
Source: Daily Express - Health - February 18, 2024 Category: Consumer Health News Source Type: news

How Pigs Could Help People Who Need Liver Transplants
In this study, eGenesis scientists used CRISPR to make not one, but 69 edits to the pig genome: three to remove the most pig-like proteins that would activate the human system to reject the liver, seven edits to add human genes to the pig liver, and 59 to inactivate pig retroviruses that could cause problems in humans. “Until CRISPR, there was no way to do that many edits easily,” says Curtis. The future of pig livers This single-patient study is just the beginning of what xenotransplants can achieve, says Shaked. The liver has two major duties in the body: regulating critical enzymes and substances such ...
Source: TIME: Health - January 18, 2024 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate Source Type: news

Hospice nurse shares three common symptoms of bile duct cancer - ‘go to the doctor’
Many people don't go to the doctor for these symptoms because they're "general and generic". (Source: Daily Express - Health)
Source: Daily Express - Health - January 15, 2024 Category: Consumer Health News Source Type: news

Research fuels advances in bile duct cancer care
Bile duct cancer, also known as cholangiocarcinoma, forms in the thin tubes that carry bile from your liver to your gallbladder and small intestine. Though relatively rare, cholangiocarcinoma is often diagnosed in later stages, making it more difficult to treat, and cases in the U.S. are increasing. In a review article published in Nature Reviews Clinical Oncology in 2023, lead author Sumera I. Ilyas, M.B.B.S., and co-authors share advances in diagnosing, staging and treating bile duct cancer. Dr.… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 13, 2024 Category: Databases & Libraries Source Type: news

Oxfordshire man with diabetes 'in limbo' after benefits refusal
Ashley Hall has also been diagnosed with bile acid malabsorption, which leaves him in constant pain. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - January 12, 2024 Category: Consumer Health News Source Type: news

Revolting video shows FIVE wiggly parasitic worms trapped inside a 70 year-old man's abdomen
A 70-year-old man who underwent a procedure to diagnose blockages in his bile duct was found to have worms in his abdomen, according to Chinese doctors. (Source: the Mail online | Health)
Source: the Mail online | Health - December 28, 2023 Category: Consumer Health News Source Type: news

Integration of Biorelevant Pediatric Dissolution Methodology into PBPK Modeling to Predict In Vivo Performance and Bioequivalence of Generic Drugs in Pediatric Populations
In this study, CDER researchers looked for potential differences in dissolution profiles based on gastrointestinal (GI) fluid volume, composition, and bile salt concentrations in adult and pediatric patients. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - December 12, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Bile duct function and disease highlighted in new research study
These ducts are a critical but poorly understood component of the human digestive system, new research helps understand the diseases affecting them. (Source: Yale Science and Health News)
Source: Yale Science and Health News - December 8, 2023 Category: Universities & Medical Training Source Type: news

Mark Shelmerdine, BAFTA L.A. Co-Founder and Producer Who Revived London Films, Dies at 78
Mark Shelmerdine, the BAFTA L.A. co-founder and producer who is credited with reviving Alexandra Korda’s London Films, died Oct. 26 in Santa Barbara after a long illness. He was 78. Shelmerdine was diagnosed with a rare form of bile duct cancer in 2016. After being treated in a trial program…#markshelmerdine #baftala #alexandrakordas #londonfilms #santabarbara #shelmerdine #houston #taylorclark #robertclark #abccinema (Source: Reuters: Health)
Source: Reuters: Health - December 2, 2023 Category: Consumer Health News Source Type: news

3D imaging modeling cost effective for pediatric surgery
3D anatomical modeling using advanced imaging software can be cost-effective in planning pediatric surgeries, according to research published October 28 in the Journal of Pediatric Surgery. A team led by Mark Ryan, MD, from the University of Texas Southwestern Medical Center in Dallas found that its modeling approach can successfully visualize pediatric anatomical structures. From there, these 3D structures can be retained for 3D printing, virtual reality usage, or as an anatomic reference. “Visualization and preoperative planning can be assisted by advanced imaging software at minimal to no cost, thereby facilitating...
Source: AuntMinnie.com Headlines - October 31, 2023 Category: Radiology Authors: Amerigo Allegretto Tags: Advanced Visualization Source Type: news

3D imaging modeling cost-effective for pediatric surgery
3D anatomical modeling using advanced imaging software can be cost-effective in planning pediatric surgeries, according to research published October 28 in the Journal of Pediatric Surgery. A team led by Mark Ryan, MD, from the University of Texas Southwestern Medical Center in Dallas found that its modeling approach can successfully visualize pediatric anatomical structures. From there, these 3D structures can be retained for 3D printing, virtual reality usage, or as an anatomic reference. “Visualization and preoperative planning can be assisted by advanced imaging software at minimal to no cost, thereby facilitating...
Source: AuntMinnie.com Headlines - October 31, 2023 Category: Radiology Authors: Amerigo Allegretto Tags: 3D Printing Source Type: news

Drug Trials Snapshot: LYTGOBI
LYTGOBI is a drug used for the treatment of adults with a type of bile duct cancer (intrahepatic cholangiocarcinoma) that has spread to other parts of the body (metastatic) or cannot not be removed by surgery (unresectable). (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 26, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news

Consumer Health: Liver cancer --  risk factors and prevention
October is Liver Cancer Awareness Month, which makes this a good time to learn more about risk factors for liver cancer and what you can do to prevent it. More than 41,000 new cases of primary liver cancer and intrahepatic bile duct cancer will be diagnosed in the U.S. this year, and nearly 30,000 people will die of these diseases, according to the American Cancer Society. Liver cancer is cancer that begins in the cells of your liver, which… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 12, 2023 Category: Databases & Libraries Source Type: news

Drug Trials Snapshot: LIVMARLI
LIVMARLI is a drug for the treatment of itching (pruritus) due to blockage of bile flow out of the liver (cholestasis) in patients with Alagille syndrome (ALGS) one year of age and older. (Source: FDA Center for Drug Evaluation and Research - What's New)
Source: FDA Center for Drug Evaluation and Research - What's New - October 4, 2023 Category: Drugs & Pharmacology Authors: FDA Source Type: news