Parts of Intestinal Scope Devices Can Break Off Inside Patients
FRIDAY, March 24, 2023 -- A medical device used to diagnose and treat pancreatic and bile duct disease is getting attention from the U.S. Food and Drug Administration after pieces have fallen off and remained in patients’ bodies.
Previously,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 24, 2023 Category: General Medicine Source Type: news
Bile Duct Cancer: Awareness, Funding Needed to Fight This Silent Killer
MONDAY, March 20, 2023 -- Lawyer, entrepreneur and avid athlete Mark Clements participated in the 2005 St. George Marathon in Utah, but ongoing stomach pains made finishing the event a struggle.“He was having some stomach pain,”... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 20, 2023 Category: General Medicine Source Type: news
Mayo Clinic Q and A: What is cholangiocarcinoma and how is it treated?
DEAR MAYO CLINIC: My mother has been experiencing unusual and persistent fatigue, abdominal pain, and jaundice. After undergoing a CT scan, her doctor diagnosed her with cholangiocarcinoma. What is this type of cancer? And what treatment options are available? ANSWER: Cholangiocarcinoma is a rare cancer that develops from the bile ducts, which are slender tubes that carry the digestive fluid bile and connect the liver to the gallbladder and small intestine. The tumor can occur anywhere along… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 21, 2023 Category: Databases & Libraries Source Type: news
Meconium: It Can Cause a Sticky Mess
Discussion
During fetal life from approximately 12-13 weeks gestation, meconium accumulates in the small bowel and migrates to the large bowel and rectum by ~20 weeks gestation. Meconium is a combination of bile, mucous, desquamated intestinal cells, bowel secretions, dessicated swallowed amniotic fluid and lanugo. It is sterile before birth and once produced is odorless with a blackish green (sometimes brown or yellow) color, and tarry or sticky quality. Defecation does not occur during fetal life unless the fetus is significantly stressed. Normal meconium passage after birth occurs within 24-48 hours of life (more often ...
Source: PediatricEducation.org - February 13, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Gallbladder & Bile Duct Cancers: Rare, Silent and Deadly. Know the Signs
WEDNESDAY, Feb. 1, 2023 – Bile duct and gallbladder cancers develop in organs deep inside the body, making them difficult to detect.
Knowing the signs of these rare cancers may help with earlier detection.
Gallbladder cancer and bile duct cancer... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 1, 2023 Category: General Medicine Source Type: news
How Good is Cholecystectomy For Biliary Dyskinesia in Pediatric Patients?
Discussion
Biliary disease includes gallstones, cholecystitis (inflammation of the gallbladder), cholangiopathy and cholangitis (pathology of the bile ducts), biliary dyskinesia, gangrene, and cancer. Some are often overlapping as gallstones often contributing to cholecystitis and cholangitis.
Biliary dyskinesia (BD) is well-recognized in adults. Adult criteria include: “abdominal pain located in the epigastrium and/or right upper quadrant along with; buildup of pain to a steady level and lasting 30 minutes or longer, pain occurring at different intervals and not daily, severe enough to interrupt activities or lead t...
Source: PediatricEducation.org - January 30, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Fecal Bile Acid to Predict Recurrence in C. Difficile Infection Fecal Bile Acid to Predict Recurrence in C. Difficile Infection
This study investigated how gut microbiota-bile acid interactions relate to the pathogenesis of C. difficile infection. Could fecal bile acids have potential as biomarkers to predict CDI recurrence?Alimentary Pharmacology & Therapeutics (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - December 28, 2022 Category: Consumer Health News Tags: Gastroenterology Journal Article Source Type: news
Maralixibat Takes Out the Itch of Rare Liver Disease
(MedPage Today) -- WASHINGTON -- Another ileal bile acid transporter inhibitor has demonstrated in a phase III trial the ability to reduce pruritus and serum bile acids for kids with progressive familial intrahepatic cholestasis (PFIC).
In children... (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - November 9, 2022 Category: Dermatology Source Type: news
Odevixibat Shows 'Encouraging Results' for Kids With Alagille Syndrome
(MedPage Today) -- WASHINGTON -- Treatment with odevixibat (Bylvay) led to early, rapid, and sustained improvements in pruritus among pediatric patients with Alagille syndrome, as well as reductions in bile acid levels, the phase III ASSERT trial... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - November 9, 2022 Category: Gastroenterology Source Type: news
Pruritus is a sign of pancreatic cancer that affects skin - caused by excess bile salts
People with pancreatic cancer could experience pruritus, or itchy skin, according to Pancreatic Cancer Action. (Source: Daily Express - Health)
Source: Daily Express - Health - November 7, 2022 Category: Consumer Health News Source Type: news
Blood, bile, melancholy and phlegm: Medicine in Shakespeare’s day
Phlegm, blood, black and yellow bile were all thought to rule human bodies and behaviors in the Bard's day. (Source: Washington Post: To Your Health)
Source: Washington Post: To Your Health - November 7, 2022 Category: Consumer Health News Authors: Erin Blakemore Source Type: news
Consumer Health: Treating liver cancer
October is Liver Cancer Awareness Month, which makes this a good time to learn more about treating liver cancer. More than 41,000 new cases of primary liver cancer and intrahepatic bile duct cancer will be diagnosed in the U.S. this year, and more than 30,000 people will die of these diseases, according to the American Cancer Society. Liver cancer is cancer that begins in the cells of your liver, which is a football-sized organ in the upper right portion… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - October 27, 2022 Category: Databases & Libraries Source Type: news
Orphan Drug Designation Given to New Mesothelioma CAR T-Cell Therapy
In early 2023, the world-class Hospital of the University of Pennsylvania will open a groundbreaking clinical trial for mesothelioma patients utilizing a next-generation immunotherapy with a novel delivery platform.
The U.S. Food and Drug Administration cleared the path in September by granting orphan drug designation for SynKIR-110, a CAR T-cell therapy designed to target solid tumors expressing a specific protein typically found in mesothelioma cancer.
By granting the orphan drug designation, the FDA can provide financial incentives such as tax credits for clinical trials and seven years of market exclusivity. It i...
Source: Asbestos and Mesothelioma News - October 5, 2022 Category: Environmental Health Authors: Fran Mannino Source Type: news
c-di-AMP signaling is required for bile salt resistance, osmotolerance, and long-term host colonization by Clostridioides difficile | Science Signaling
Cyclic di-AMP degradation protects Clostridioides difficile from osmotic and bile salt stresses and promotes host colonization. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - September 6, 2022 Category: Science Source Type: news
Diabetes Drug for Bile Acid Diarrhea Bests Standard of Care in Small Trial
(MedPage Today) -- Glucagon-like peptide 1 (GLP-1) receptor agonist liraglutide (Victoza, Saxenda) may be superior to colesevelam (Welchol) for reducing stool frequency in patients with moderate-to-severe bile acid diarrhea, a small randomized... (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - July 21, 2022 Category: Gastroenterology Source Type: news
