Studies Document Some Severe Outcomes After Drug-induced Liver Injury
New insights into outcomes from drug-induced liver injury include the rate of fatal outcomes, frequency of bile duct damage and loss, and racial/ethnic disparities in disease severity. (Source: NIDDK News)
Source: NIDDK News - June 23, 2018 Category: Endocrinology Source Type: news
Albireo Appoints Jason G. Duncan as General Counsel and Secretary
BOSTON, June 18, 2018 -- (Healthcare Sales & Marketing Network) -- Albireo Pharma, Inc. (Nasdaq:ALBO), a clinical-stage orphan pediatric liver disease company developing novel bile acid modulators, today announced the appointment of Jason G. Duncan as Gene... Biopharmaceuticals, Personnel Albireo Pharma, bile acid modulator, liver disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 18, 2018 Category: Pharmaceuticals Source Type: news
Medical News Today: What causes bile duct obstruction?
A bile duct obstruction is when one of the tubes that carries bile between the liver, gallbladder, and small intestine becomes blocked. This can lead to severe complications if left untreated and may require surgery. Here, we look at the leading causes, symptoms, diagnosis, and treatment of bile duct obstruction. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 11, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news
Albireo Elects Anne Klibanski and Stephanie Okey to Board of Directors
BOSTON, June 08, 2018 -- (Healthcare Sales & Marketing Network) -- Albireo Pharma, Inc. (Nasdaq:ALBO), a clinical-stage orphan pediatric liver disease company developing novel bile acid modulators, today announced the election of Anne Klibanski, M.D., and ... Biopharmaceuticals, Gastroenterology, Personnel Albireo Pharma, bile acid modulator, liver disease (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - June 8, 2018 Category: Pharmaceuticals Source Type: news
ERCP During Lap Chole Tied to Best Outcomes for Choledocholithiasis ERCP During Lap Chole Tied to Best Outcomes for Choledocholithiasis
For patients with gallstones in the common bile duct, a so-called rendezvous approach is associated with the highest rates of safety and success compared with three other techniques, researchers in Italy say.Reuters Health Information (Source: Medscape General Surgery Headlines)
Source: Medscape General Surgery Headlines - June 7, 2018 Category: Surgery Tags: Gastroenterology News Source Type: news
GERD Trends Shift and PPI Safety is a Question
News from DDW 2018: GERD is appearing in younger patients; PPI first use linked to many adverse events; and, new test for bile salts in saliva. (Source: ConsultantLive)
Source: ConsultantLive - June 6, 2018 Category: Internal Medicine Authors: Veronica Hackethal, MD Tags: Conferences/Digestive Disease Week Source Type: news
Medical News Today: Gut bacteria control cancer immunity in the liver
Scientists discover that a Clostridium gut microbe species blocks the liver's immune response to primary and metastatic tumors by altering bile acids. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 25, 2018 Category: Consumer Health News Tags: Cancer / Oncology Source Type: news
Bile acids and liver cancer
(Source: ScienceNOW)
Source: ScienceNOW - May 24, 2018 Category: Science Authors: Kelly, P. N. Tags: Immunology twis Source Type: news
Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells
Primary liver tumors and liver metastasis currently represent the leading cause of cancer-related death. Commensal bacteria are important regulators of antitumor immunity, and although the liver is exposed to gut bacteria, their role in antitumor surveillance of liver tumors is poorly understood. We found that altering commensal gut bacteria in mice induced a liver-selective antitumor effect, with an increase of hepatic CXCR6+ natural killer T (NKT) cells and heightened interferon- production upon antigen stimulation. In vivo functional studies showed that NKT cells mediated liver-selective tumor inhibition. NKT cell accum...
Source: ScienceNOW - May 24, 2018 Category: Science Authors: Ma, C., Han, M., Heinrich, B., Fu, Q., Zhang, Q., Sandhu, M., Agdashian, D., Terabe, M., Berzofsky, J. A., Fako, V., Ritz, T., Longerich, T., Theriot, C. M., McCulloch, J. A., Roy, S., Yuan, W., Thovarai, V., Sen, S. K., Ruchirawat, M., Korangy, F., Wang, Tags: Immunology, Online Only r-articles Source Type: news
Why are we living in an age of anger – is it because of the 50-year rage cycle?
From passive-aggressive notes on ambulance windscreens to bilious political discourse, it feels as though society is suddenly consumed by fury. What is to blame for this outpouring of aggression?A neighbourobjected to a young couple from Newcastle being naked in their own home. “We are sick of seeing big bums, big boobs and little willy,” was the core message of the note, crescendoing to: “We will report you both for indecent exposure.” It is such a small thing, banal, without consequence. It connects to no wider narrative and conveys nothing but the bubbling disco mfort of human beings living near each other. Yet ...
Source: Guardian Unlimited Science - May 16, 2018 Category: Science Authors: Zoe Williams Tags: Psychology Social media Digital media Social networking Science Source Type: news
Handful of walnuts a day may prevent heart disease and bowel cancer by encouraging 'good' bacteria
Researchers from the University of Illinois found eating a third of a cup of walnuts for six weeks reduces the production of excess bile acids, as well as lowering 'bad' cholesterol levels. (Source: the Mail online | Health)
Source: the Mail online | Health - May 4, 2018 Category: Consumer Health News Source Type: news
'Rapid autopsy' races the clock to unlock mysteries of cancer
After Keith Beck died of bile duct cancer last year, family members said more than 900 people showed up to pay respects to the popular athletic director at the University of Findlay in northwestern Ohio. (Source: CNN.com - Health)
Source: CNN.com - Health - May 3, 2018 Category: Consumer Health News Source Type: news
'Rapid autopsy' to unlock mysteries of cancer
After Keith Beck died of bile duct cancer last year, family members said more than 900 people showed up to pay respects to the popular athletic director at the University of Findlay in northwestern Ohio. (Source: CNN.com - Health)
Source: CNN.com - Health - May 3, 2018 Category: Consumer Health News Source Type: news
How a New Kind of Autopsy Is Helping in the Fight Against Cancer
After Keith Beck died of bile duct cancer last year, family members said, more than 900 people showed up to pay respects to the popular athletic director at the University of Findlay in northwestern Ohio.
Many were former students who recalled acts of kindness during Beck’s nearly 30-year career: $20 given to a kid who was broke, textbooks bought for a student whose parents were going through bankruptcy, a spot cleared to sleep on Beck’s living room floor.
But few knew about Beck’s final gesture of generosity. The 59-year-old had agreed to a “rapid autopsy,” a procedure conducted within hours ...
Source: TIME: Health - April 24, 2018 Category: Consumer Health News Authors: JoNel Aleccia / Kaiser Health News Tags: Uncategorized Cancer healthytime Source Type: news
Novel Non-Bile FXR Agonist Promising in PBC Patients
(MedPage Today) -- Phase II trial interim analysis found dose-dependent response, good safety profile (Source: MedPage Today Gastroenterology)
Source: MedPage Today Gastroenterology - April 16, 2018 Category: Gastroenterology Source Type: news
