Bile Duct Cancer (Cholangiocarcinoma)
(Source: eMedicineHealth.com)
Source: eMedicineHealth.com - February 2, 2018 Category: General Medicine Source Type: news

Bile acids fire up fat burning
(Ecole Polytechnique F é d é rale de Lausanne) EPFL scientists have discovered a novel role for bile acids: converting energy-storing white fat depots into energy-expending beige fat. The study is published in Nature Communications. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - January 16, 2018 Category: International Medicine & Public Health Source Type: news

Medical News Today: What you should know about the HIDA scan
The HIDA scan is used to view the liver, gallbladder, bile ducts, and small intestine. Included are details on side effects and why it is done. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 3, 2018 Category: Consumer Health News Tags: Radiology / Nuclear Medicine Source Type: news

RedHill teams with Mayo Clinic, MD Anderson on new cancer trial
Tel-Aviv, Israel-based RedHill Biopharma (Nasdaq: RDHL) – which is continuing to build up its U.S. commercial operations based in Raleigh – is teaming with the Mayo Clinic and The University of Texas MD Anderson Cancer Center on a new cancer trial. The new Phase IIa study is for YELIVA – a product candidate RedHill acquired from Apogee Biotechnolo gy back in 2015 – for the treatment of cholangiocarcinoma, or bile duct cancer. It will enroll patients at Mayo Clinic campuses in both Arizona… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - December 28, 2017 Category: Pharmaceuticals Authors: Jennifer Henderson Source Type: news

Medical News Today: Biliary colic: Causes and treatment
Biliary colic can happen when a gallstone blocks a bile duct, causing intense stomach pain. It is also known as a gallstone attack or gallbladder attack. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 27, 2017 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

CD4 T cells, xenobiotic transporters, and metabolites in inflammatory bowel diseases
(Osaka University) Few studies have investigated the interaction between intestinal T cells with metabolites. Researchers have now shown in mice CD4+ T effector (Teff) cells upregulate the protein Mdr1 in the ileum to maintain homeostasis in the presence of the metabolite bile acid. Mice lacking Mdr1 display mucosal dysfunction and induce Crohn's disease-like ileitis. Their findings suggest that T cell adaptation to enterohepatic bile acid circulation in the ileum safeguards intestinal homeostasis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 26, 2017 Category: International Medicine & Public Health Source Type: news

What is DIOS?
Discussion Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane receptor (CFTR). It is found in the epithelium of the bronchi, intestine, pancreatic duct and biliary tree. It regulates chloride, bicarbonate and water secretion. The heterozygous state helps prevent against secretory diarrhea, but the homozygous state causes thickened secretions in the hollow tubes of the lungs and digestive tract. There are multiple mutations (> 2000) which have been currently classified into classes depending on their protein production and activity. CF patients generally are l...
Source: PediatricEducation.org - December 18, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

IBS symptoms? THIS may be the real cause of your watery diarrhoea
IRRITABLE BOWEL SYNDROME symptoms may actually be caused by another condition, known as bile acid diarrhoea. (Source: Daily Express - Health)
Source: Daily Express - Health - December 5, 2017 Category: Consumer Health News Source Type: news

The real reason you may have an upset tum
Experts believe up to a third of people diagnosed with IBS may, in fact, have bile acid diarrhoea, with around one in 100 people affected overall. (Source: the Mail online | Health)
Source: the Mail online | Health - December 5, 2017 Category: Consumer Health News Source Type: news

Children with Alagille Syndrome have malformed bile ducts
(Karolinska Institutet) Serious liver and heart problems can affect children with Alagille Syndrome early in life. While there is as yet no cure, researchers at Karolinska Institutet in Sweden have discovered that the liver disease part of the syndrome is caused by specific malformations of the bile ducts. The results, which are published in the journal Gastroenterology, were discovered with the aid of a new mouse model that can now be used to develop and test new therapies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 21, 2017 Category: International Medicine & Public Health Source Type: news

Police save lives every day, just not this way — a liver for Sloan
Sloane and Lt. Tenney A police officer’s job is all about action and reaction. “We see something, react to it and, typically, it’s over quickly,” says Lt. Steve Tenney of the Keene, New Hampshire, Police Department. But on the morning of Sept. 8, while Steve lay in a hospital bed at Lahey Hospital & Medical Center in Burlington, Massachusetts, action/reaction wasn’t part of the equation. This time, there was time to think. Even so, the decision to donate a piece of his liver to save Sloan — a baby he’d never even met — was made without hesitation. “I did what anyone would have done,” he says. Sloan ...
Source: Thrive, Children's Hospital Boston - November 8, 2017 Category: Pediatrics Authors: Emily Williams Tags: Diseases & Conditions Our Patients’ Stories biliary atresia Dr. Christine Lee Dr. Heung-Bae Kim Dr. Khashavar Vakili Liver transplant Liver Transplant Program living donor Source Type: news

UCLA Health launches pioneering mobile stroke unit with support from L.A. County
Roughly every 40 seconds, someone in the United States will have a stroke. Almost every four minutes, one of those people will die as a result. Against that backdrop, UCLA Health has officially launched the first mobile stroke unit on the West Coast, enabling rapid delivery of brain-saving medications to stroke patients who might otherwise face debilitating delays in treatment.  As part of the first phase of a pilot program, the specialized ambulance unit and highly trained personnel began responding in September to select 911 calls in Santa Monica in coordination with the Santa Monica Fire Department. With support from t...
Source: UCLA Newsroom: Health Sciences - October 26, 2017 Category: Universities & Medical Training Source Type: news

Cholesterol Vaccine?
I saw this headline not long ago and it made my jaw drop. “Daily statin use to lower cholesterol may soon be a thing of the past.” I thought maybe — finally — the war on cholesterol was coming to an end. It wasn’t. Instead, it turns out Big Pharma is doubling down on cholesterol drugs. They’ve found a new multi-billion dollar scam. Let me explain… Statins have been blockbusters for the drug companies. Worldwide sales hit $34 billion in one year. But most of these drugs have come to the end of their patents. Profits are starting to dip. Big Pharma needs another patent to replace them. So instead of statin ...
Source: Al Sears, MD Natural Remedies - October 19, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Mayo Clinic Q and A: Primary sclerosing cholangitis
DEAR MAYO CLINIC: What causes primary sclerosing cholangitis? How long does it take for it to progress? ANSWER: Primary sclerosing cholangitis, or PSC, is a chronic inflammatory disease of the bile ducts that may lead to severe liver damage and liver failure. PSC also can be associated with an increased risk of cancers in the [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - September 22, 2017 Category: Databases & Libraries Source Type: news

Will Disposable Caps Solve Dirty Scope Problems?
Reprocessing duodenoscopes after they’ve journeyed through a patient’s GI tract has been a pain in the you-know-what for pretty much everyone involved. These flexible lighted instruments are quite complex, with a lot of small working parts that are difficult to clean. So it’s all too easy for contaminated tissue or fluid to get trapped in the crevices of the device and allow nasty little superbugs to spread to other patients. And yet, duodenoscopes enable more than 500,000 necessary procedures a year for patients with bile duct disorders and other upper GI problems, according to FDA. That’s why the agency is optimi...
Source: MDDI - September 21, 2017 Category: Medical Devices Authors: Amanda Pedersen Tags: MD & M Minneapolis Sterilization Regulatory and Compliance Source Type: news