Changes in Spinal Instability After Conventional Radiotherapy for Painful Vertebral Bone Metastases
In conclusion, there was improvement of pain, and recalcification results in regaining spinal stability over time after RT although vertebral body collapse and malalignment occur in some irradiated vertebrae. Clinicians should pay attention to PLISE in predicting continuous potentially unstable/unstable spine.PMID:38686892 | DOI:10.1177/10732748241250219 (Source: Cancer Control)
Source: Cancer Control - April 30, 2024 Category: Cancer & Oncology Authors: Eiji Nakata Shinsuke Sugihara Ryuichi Nakahara Haruyoshi Katayama Takuto Itano Toshifumi Ozaki Source Type: research

Microwave ablation combined with percutaneous vertebroplasty for treating painful non-small cell lung cancer with spinal metastases under real-time temperature monitoring
CONCLUSIONS: MWA combined with PVP can significantly relieve pain and improve patients' quality of life, which implied this is an effective treatment option for painful NSCLC with spinal metastases. Additionally, its efficacy should be further verified through the mid- and long-term studies.PMID:38687923 | DOI:10.4103/jcrt.jcrt_1074_23 (Source: Cell Research)
Source: Cell Research - April 30, 2024 Category: Cytology Authors: Linlin Wu Miaomiao Hu Peishun Li Qirong Man Qianqian Yuan Xusheng Zhang Yuanyuan Qiu Lili Chen Jing Fan Kaixian Zhang Source Type: research

The effect of graded activity and pain education after lumbar spinal fusion on sedentary behavior 3 and 12 months post-surgery: a randomized controlled trial
CONCLUSION: Compared with usual care, GAPE had no effect on short-term changes in sedentary behaviour but GAPE had a statistically, but possibly not clinically effect on sedentary behaviour 12 months after LSF. Further, the behavioural intervention was safe to perform.PMID:38685291 | DOI:10.1016/j.apmr.2024.04.005 (Source: Health Physics)
Source: Health Physics - April 30, 2024 Category: Physics Authors: Heidi Tegner Nanna Rolving Marius Henriksen Rachid Bech-Azeddine Mari Lundberg Bente Appel Esbensen Source Type: research

Conservative management of spontaneous spinal epidural hematoma: A case report with favorable prognosis
Key Clinical MessageSudden spinal epidural hematoma (SSEH) is relatively rare. Sudden pain from the neck to the back and subsequent extremity paralysis necessitate immediate head and cervical magnetic resonance imaging or computed tomography, keeping SSEH in mind. Although surgery is recommended for progressive paralysis, conservative treatment is indicated for mildly symptomatic cases. (Source: Clinical Case Reports)
Source: Clinical Case Reports - April 30, 2024 Category: General Medicine Authors: Satoshi Nakao, Hirohito Hirata, Tomohito Yoshihara, Takaomi Kobayashi, Masatsugu Tsukamoto, Yoshiaki Egashira, Masaaki Mawatari, Tadatsugu Morimoto Tags: CASE REPORT Source Type: research

GSE265957 Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain
Contributors : Kevin Lister ; Sonali Uttam ; Marc Pairsien ; Arkady KhoutorskySeries Type : Expression profiling by high throughput sequencing ; OtherOrganism : Mus musculusSensitization of spinal nociceptive circuits plays a cardinal role in neuropathic pain. This sensitization depends on new gene expression that is primarily regulated via transcriptional and translational control mechanisms. The relative roles of these mechanisms in regulating gene expression in the clinically relevant chronic phase of neuropathic pain are not well understood. Here, we show that changes in gene expression in the spinal cord during th...
Source: GEO: Gene Expression Omnibus - April 30, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Other Mus musculus Source Type: research

Mindful Breathing as an Adjunctive Approach to Chronic Low Back Pain Management: A Scoping Review
Chronic low back pain (CLBP) is a common and challenging condition. This scoping review explores the literature on mindful breathing's role in managing CLBP, either alone or alongside physiotherapy. (Source: Pain Management Nursing)
Source: Pain Management Nursing - April 30, 2024 Category: Nursing Authors: Roberto Tedeschi Tags: Review Article Source Type: research

Molecules, Vol. 29, Pages 2079: The Analgesic Potential of Litsea Species: A Systematic Review
hayati Ahmad Various plant species from the Litsea genus have been claimed to be beneficial for pain relief. The PRISMA approach was adopted to identify studies that reported analgesic properties of plants from the Litsea genus. Out of 450 records returned, 19 primary studies revealed the analgesic potential of nine Litsea species including (1) Litsea cubeba, (2) Litsea elliptibacea, (3) Litsea japonica, (4) Litsea glutinosa, (5) Litsea glaucescens, (6) Litsea guatemalensis, (7) Litsea lancifolia, (8) Litsea liyuyingi and (9) Litsea monopetala. Six of the species, 1, 3, 4, 7, 8 and 9, demonstrated peripheral antinocice...
Source: Molecules - April 30, 2024 Category: Chemistry Authors: May Poh Yik Goh Raudhatun Na ’emah Samsul Amal Widaad Mohaimin Hui Poh Goh Nurul Hazlina Zaini Nurolaini Kifli Norhayati Ahmad Tags: Review Source Type: research

Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice
CONCLUSION: Our findings indicated that SLITRK1 in the amygdala plays an important role in chronic pain and related ADD, and may prove to be a potential therapeutic target for chronic NPP-ADD comorbidity.PMID:38682225 | DOI:10.31083/j.jin2304082 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ruitong Chu Ye Lu Xiaoyi Fan Chengyuan Lai Jian Li Rui Yang Zhenghua Xiang Chaofeng Han Mouli Tian Hongbin Yuan Source Type: research

Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice
CONCLUSION: Our findings indicated that SLITRK1 in the amygdala plays an important role in chronic pain and related ADD, and may prove to be a potential therapeutic target for chronic NPP-ADD comorbidity.PMID:38682225 | DOI:10.31083/j.jin2304082 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ruitong Chu Ye Lu Xiaoyi Fan Chengyuan Lai Jian Li Rui Yang Zhenghua Xiang Chaofeng Han Mouli Tian Hongbin Yuan Source Type: research

Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice
CONCLUSION: Our findings indicated that SLITRK1 in the amygdala plays an important role in chronic pain and related ADD, and may prove to be a potential therapeutic target for chronic NPP-ADD comorbidity.PMID:38682225 | DOI:10.31083/j.jin2304082 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ruitong Chu Ye Lu Xiaoyi Fan Chengyuan Lai Jian Li Rui Yang Zhenghua Xiang Chaofeng Han Mouli Tian Hongbin Yuan Source Type: research

Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice
CONCLUSION: Our findings indicated that SLITRK1 in the amygdala plays an important role in chronic pain and related ADD, and may prove to be a potential therapeutic target for chronic NPP-ADD comorbidity.PMID:38682225 | DOI:10.31083/j.jin2304082 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ruitong Chu Ye Lu Xiaoyi Fan Chengyuan Lai Jian Li Rui Yang Zhenghua Xiang Chaofeng Han Mouli Tian Hongbin Yuan Source Type: research

What gets measured gets managed: A scoping review of musculoskeletal research conducted within practice-based research networks
Am J Phys Med Rehabil. 2024 Apr 26. doi: 10.1097/PHM.0000000000002485. Online ahead of print.ABSTRACTMusculoskeletal (MSK) conditions are often managed in primary care settings. To facilitate research and health care quality, practice-based research networks (PBRNs) offer sustained collaborations between clinicians and researchers. A scoping review was conducted to describe characteristics of PBRNs used for MSK research and MSK research conducted through PBRNs. PBRNs were identified from 1) MSK-studies identified In OVID Medline, CINAHL, and Embase databases from inception to 05 February 2023 and in ClinicalTrials.gov; and...
Source: Health Physics - April 29, 2024 Category: Physics Authors: Rahim Lalji Javier Mu ñoz Laguna Jael Kauth L éonie Hofstetter Astrid Kurmann Jon Adams Alice Kongsted Viktor von Wyl Milo A Puhan Cesar A Hincapi é Source Type: research

Analysis of Ionomic Profiles of Spinal Cords in a Rat Model with Bone Cancer Pain
CONCLUSION: Taken together, inoculation of Walker 256 cells into the left tibia contributes to BCP, which could be closely correlated by some elements. The findings provided novel information on the relationship between the ionome and BCP.PMID:38682106 | PMC:PMC11055530 | DOI:10.2147/JPR.S447282 (Source: Cancer Control)
Source: Cancer Control - April 29, 2024 Category: Cancer & Oncology Authors: Jinlu Huang Jiugeng Chen Le Ma Xieyi Zhu Lili Wan Xinyan Li Cheng Guo Source Type: research

Analysis of Ionomic Profiles of Spinal Cords in a Rat Model with Bone Cancer Pain
CONCLUSION: Taken together, inoculation of Walker 256 cells into the left tibia contributes to BCP, which could be closely correlated by some elements. The findings provided novel information on the relationship between the ionome and BCP.PMID:38682106 | PMC:PMC11055530 | DOI:10.2147/JPR.S447282 (Source: Cell Research)
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Jinlu Huang Jiugeng Chen Le Ma Xieyi Zhu Lili Wan Xinyan Li Cheng Guo Source Type: research

Changes in SLITRK1 Level in the Amygdala Mediate Chronic Neuropathic Pain-Induced Anxio-Depressive Behaviors in Mice
CONCLUSION: Our findings indicated that SLITRK1 in the amygdala plays an important role in chronic pain and related ADD, and may prove to be a potential therapeutic target for chronic NPP-ADD comorbidity.PMID:38682225 | DOI:10.31083/j.jin2304082 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Ruitong Chu Ye Lu Xiaoyi Fan Chengyuan Lai Jian Li Rui Yang Zhenghua Xiang Chaofeng Han Mouli Tian Hongbin Yuan Source Type: research