Investigating Cervical Flexion-Relaxation Ratio in Subjects with Cervical Lateral Spinal Stenosis Compared with Asymptomatic Controls: a case control study
The cervical flexion-relaxation ratio (FRR) is known as a quantitative measure of the ability of the cervical extensor muscles to relax during the full flexion of the cervical spine. Compared with subjects suffering from non-specific neck pain, the changes occurring in the pattern of the neck muscles' functions in cases with cervical spinal stenosis are not yet well understood. Therefore, this study aimed to compare cervical FRR in subjects with cervical lateral spinal stenosis and asymptomatic controls. (Source: Journal of Bodywork and Movement Therapies)
Source: Journal of Bodywork and Movement Therapies - April 26, 2024 Category: Physiotherapy Authors: Khodabakhsh Javanshir, Zahra Akbarnejad-Basra, Payam Saadat, Roghayeh Mousavi-Khatir Source Type: research

Cutibacterium Acnes in Spine Surgery: Pathophysiology, Diagnosis, and Treatment
Cutibacterium acnes (C. acnes) previously named Propionibacterium acnes (P. acnes) has been increasingly recognized by spine surgeons as a cause of indolent post-surgical spinal infection. Patients infected with C acnes may present with pseudarthrosis or nonspecific back pain. Currently, microbiological tissue cultures remain the gold standard in diagnosing C. acnes infection. Ongoing research into using genetic sequencing as a diagnostic method shows promising results and may be another future way of diagnosis. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Makeen Baroudi, Mohammad Daher, Russell D Parks, Jerzy George Gregoryczyk, Mariah Balmaceno-Criss, Christopher L McDonald, Bassel G Diebo, Alan H Daniels Source Type: research

Development and Validation of a Radiomics-Based Model for Predicting Osteoporosis in Patients with Lumbar Compression Fractures
Osteoporosis, a metabolic bone disorder, markedly elevates fracture risks, with vertebral compression fractures being predominant. Antiosteoporotic treatments for patients with osteoporotic vertebral compression fractures (OVCF) lessen both the occurrence of subsequent fractures and associated pain. Thus, diagnosing osteoporosis in OVCF patients is vital. (Source: The Spine Journal)
Source: The Spine Journal - April 26, 2024 Category: Orthopaedics Authors: Sunqi Nian, Yayu Zhao, Chengjin Li, Kang Zhu, Na Li, Weichao Li, Jiayu Chen Tags: Clinical Study Source Type: research

News at a glance: Plants ’ tree of life, conserving U.S. federal lands, and entertaining invertebrate sentience
CONSERVATION Interior Department boosts restoration The largest manager of public lands in the United States last week announced it will manage them to promote ecological stewardship, while continuing to allow extractive commercial uses such as mining, oil drilling, and cattle grazing. The Bureau of Land Management (BLM) oversees nearly 1 million square kilometers of federal land, about 10% of the country’s landmass, mostly in Western states. Under a rule issued on 18 April, BLM will now assess the ecological condition of all hectares it manages , not just grazing land. The agency will a...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research

Macrophage: A key player in neuropathic pain
Int Rev Immunol. 2024 Apr 25:1-14. doi: 10.1080/08830185.2024.2344170. Online ahead of print.ABSTRACTResearch on the relationship between macrophages and neuropathic pain has flourished in the past two decades. It has long been believed that macrophages are strong immune effector cells that play well-established roles in tissue homeostasis and lesions, such as promoting the initiation and progression of tissue injury and improving wound healing and tissue remodeling in a variety of pathogenesis-related diseases. They are also heterogeneous and versatile cells that can switch phenotypically/functionally in response to the m...
Source: International Reviews of Immunology - April 25, 2024 Category: Allergy & Immunology Authors: Ying Ye Hao Cheng Yan Wang Yan Sun Li-Dong Zhang Jun Tang Source Type: research

Differential relationships between physical activity and pain phenotypes in individuals with spinal cord injury
CONCLUSION: Differential relationships exist between pain phenotypes and MVPA in individuals with SCI. Pain location differed between the subgroups of nociceptive pain, which we presume may indicate the presence of nociplastic pain in some individuals. These results may contribute to the advancement of personalized pain management by targeting non-pharmacological interventions for specific pain phenotypes.Trial registration: ClinicalTrials.gov identifier: NCT05236933..PMID:38661677 | DOI:10.1080/10790268.2024.2344315 (Source: Journal of Spinal Cord Medicine)
Source: Journal of Spinal Cord Medicine - April 25, 2024 Category: Orthopaedics Authors: Alexandra Canori Donna L Coffman W Geoffrey Wright Margaret A Finley Shivayogi V Hiremath Source Type: research

Macrophage: A key player in neuropathic pain
Int Rev Immunol. 2024 Apr 25:1-14. doi: 10.1080/08830185.2024.2344170. Online ahead of print.ABSTRACTResearch on the relationship between macrophages and neuropathic pain has flourished in the past two decades. It has long been believed that macrophages are strong immune effector cells that play well-established roles in tissue homeostasis and lesions, such as promoting the initiation and progression of tissue injury and improving wound healing and tissue remodeling in a variety of pathogenesis-related diseases. They are also heterogeneous and versatile cells that can switch phenotypically/functionally in response to the m...
Source: International Reviews of Immunology - April 25, 2024 Category: Allergy & Immunology Authors: Ying Ye Hao Cheng Yan Wang Yan Sun Li-Dong Zhang Jun Tang Source Type: research

Differential relationships between physical activity and pain phenotypes in individuals with spinal cord injury
CONCLUSION: Differential relationships exist between pain phenotypes and MVPA in individuals with SCI. Pain location differed between the subgroups of nociceptive pain, which we presume may indicate the presence of nociplastic pain in some individuals. These results may contribute to the advancement of personalized pain management by targeting non-pharmacological interventions for specific pain phenotypes.Trial registration: ClinicalTrials.gov identifier: NCT05236933..PMID:38661677 | DOI:10.1080/10790268.2024.2344315 (Source: Journal of Spinal Cord Medicine)
Source: Journal of Spinal Cord Medicine - April 25, 2024 Category: Orthopaedics Authors: Alexandra Canori Donna L Coffman W Geoffrey Wright Margaret A Finley Shivayogi V Hiremath Source Type: research

Macrophage: A key player in neuropathic pain
Int Rev Immunol. 2024 Apr 25:1-14. doi: 10.1080/08830185.2024.2344170. Online ahead of print.ABSTRACTResearch on the relationship between macrophages and neuropathic pain has flourished in the past two decades. It has long been believed that macrophages are strong immune effector cells that play well-established roles in tissue homeostasis and lesions, such as promoting the initiation and progression of tissue injury and improving wound healing and tissue remodeling in a variety of pathogenesis-related diseases. They are also heterogeneous and versatile cells that can switch phenotypically/functionally in response to the m...
Source: International Reviews of Immunology - April 25, 2024 Category: Allergy & Immunology Authors: Ying Ye Hao Cheng Yan Wang Yan Sun Li-Dong Zhang Jun Tang Source Type: research

Differential relationships between physical activity and pain phenotypes in individuals with spinal cord injury
CONCLUSION: Differential relationships exist between pain phenotypes and MVPA in individuals with SCI. Pain location differed between the subgroups of nociceptive pain, which we presume may indicate the presence of nociplastic pain in some individuals. These results may contribute to the advancement of personalized pain management by targeting non-pharmacological interventions for specific pain phenotypes.Trial registration: ClinicalTrials.gov identifier: NCT05236933..PMID:38661677 | DOI:10.1080/10790268.2024.2344315 (Source: Journal of Spinal Cord Medicine)
Source: Journal of Spinal Cord Medicine - April 25, 2024 Category: Orthopaedics Authors: Alexandra Canori Donna L Coffman W Geoffrey Wright Margaret A Finley Shivayogi V Hiremath Source Type: research

Macrophage: A key player in neuropathic pain
Int Rev Immunol. 2024 Apr 25:1-14. doi: 10.1080/08830185.2024.2344170. Online ahead of print.ABSTRACTResearch on the relationship between macrophages and neuropathic pain has flourished in the past two decades. It has long been believed that macrophages are strong immune effector cells that play well-established roles in tissue homeostasis and lesions, such as promoting the initiation and progression of tissue injury and improving wound healing and tissue remodeling in a variety of pathogenesis-related diseases. They are also heterogeneous and versatile cells that can switch phenotypically/functionally in response to the m...
Source: International Reviews of Immunology - April 25, 2024 Category: Allergy & Immunology Authors: Ying Ye Hao Cheng Yan Wang Yan Sun Li-Dong Zhang Jun Tang Source Type: research

Trajectories of health-related quality of life following road trauma: Latent growth mixture modeling across a 12-month cohort study
CONCLUSIONS: This study highlighted the heterogeneity of HRQoL trajectories following RT injury and the importance of considering differences between characteristics of survivors. In addition to injury type and severity, outcome is related to demographic factors, pre-injury health and pre-injury psychological factors.PMID:38663274 | DOI:10.1016/j.aap.2024.107574 (Source: Accident; Analysis and Prevention.)
Source: Accident; Analysis and Prevention. - April 25, 2024 Category: Accident Prevention Authors: Somayeh Momenyan Herbert Chan Shannon Erdelyi Lulu X Pei Leona K Shum Lina Jae John Taylor John A Staples Stirling Bryan Jeffrey R Brubacher Source Type: research

Surgeon Perceptions of Performing Transforaminal Lumbar Interbody Fusion in an Ambulatory Surgical Center vs Hospital Setting in the Elderly Population: Results of a Surgeon Survey
CONCLUSION: Our survey data show that surgeons' perceptions of current CMS rules and regulations may hinder the transition into the ASC setting because they think the reimbursement is too low and the regulatory burden is too high. ASCs have disproportionally higher initial acquisition and ongoing costs related to staff training and maintenance of the TLIF technology that CMS should consider when determining the appropriate financial remuneration for these complex procedures.CLINICAL RELEVANCE: ASC offers a viable and attractive option for their TLIF procedure with the advantage of same-day discharge and at-home recovery.PM...
Source: Pain Physician - April 25, 2024 Category: Anesthesiology Authors: Kai-Uwe Lewandrowski Abduljabbar Alhammoud Scott M Schlesinger Benjamin R Gelber Mark B Gerber Morgan Lorio Interamerican Society for Minimally Invasive Spine Surgery (SICCMI) International Society for the Advancement of Spine Surgery Source Type: research