PCR-positive meningococcal CSF infection without pleocytosis but high IL-6 and IL-8
ConclusionsWe present a rare case of meningococcal infection of the CSF in a SLE patient without further CSF abnormalities. We discuss the involvement of early antibiotic treatment and the role of the patient ’s immune status in the normal CSF findings of this case. Moreover, this case demonstrates the importance of early antibiotic therapy in bacterial meningitis for the clinical outcome. (Source: Infection)
Source: Infection - April 27, 2024 Category: Infectious Diseases Source Type: research

Poor postoperative pain control is associated with poor long-term patient-reported outcomes after elective spine surgery: an observational cohort study
A significant proportion of patients experience poorly controlled surgical pain and fail to achieve satisfactory clinical improvement after spine surgery. However, a direct association between these variables has not been previously demonstrated. (Source: The Spine Journal)
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: Michael M.H. Yang, Rena Far, Jay Riva-Cambrin, Tolulope T. Sajobi, Steven Casha Tags: Clinical Study Source Type: research

Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study
CONCLUSION: SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.PMID:38669487 | DOI:10.3233/NRE-230263 (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - April 26, 2024 Category: Rehabilitation Authors: Youngoh Bae Hohyun Jung Nakyung Shin Masoud Rahmati Raphael Udeh Abdolreza Kazemi Yusheng Li Marco Solmi Muhammad Syafrudin Norma Latif Fitriyani Guillaume Fond Laurent Boyer Seung Won Lee Source Type: research

Opiate-reduction protocol for common outpatient spinal procedures: a long-term feasibility study and single-center experience
CONCLUSIONS: A standardized discharge protocol for postoperative outpatient spinal procedures can lead to long-term reductions in opioid discharge quantity, without compromising patient safety or increasing the utilization of hospital resources through readmissions, refill requests, or clinic phone calls. This study provides an example of a feasible and effective discharge prescription regimen that may be generalizable to common outpatient neurosurgical procedures with long-term evidence that a small intervention can lead to ongoing reduced quantities of postoperative opioids at the time of discharge.PMID:38669713 | DOI:10...
Source: Journal of Neurosurgery - April 26, 2024 Category: Neurosurgery Authors: Nicholas Eley Aiyush Bansal Murad Alostaz Rakesh Kumar Jean-Christophe Leveque Philip K Louie Source Type: research

Prevalence and associated factors of non-traumatic knee pain in high school volleyball players: a cross-sectional study
CONCLUSION: Factors associated with knee pain include a history of LBP and reduced flexibility on the heel-buttock distance test. The study highlights the need for a comprehensive approach, considering the coexistence of LBP and focusing on improving anterior thigh flexibility.PMID:38669135 | DOI:10.1080/00913847.2024.2348439 (Source: The Physician and Sportsmedicine Online)
Source: The Physician and Sportsmedicine Online - April 26, 2024 Category: Sports Medicine Authors: Yasuaki Mizoguchi Kenta Suzuki Naoki Shimada Hiroyuki Naka Toby Hall Kiyokazu Akasaka Source Type: research

Analgesic Mechanism of Dexmedetomidine and Esketamine in Rats with Spinal Cord Injury
CONCLUSIONS: Treatment using DEX combined with ESK improves the motor function, inhibits inflammation and astrocyte activity, and exerts analgesic effects on rats with SCI. These findings can serve as a reference for the selection of multi-modal analgesics.PMID:38665020 | DOI:10.24976/Discov.Med.202436183.67 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Huiting Zhao Zhuocheng Li Source Type: research

Development and content validity of the caregiver assisted transfer technique instrument
Assist Technol. 2024 Apr 26:1-9. doi: 10.1080/10400435.2024.2336334. Online ahead of print.ABSTRACTInformal caregivers often provide transfer assistance to individuals with disabilities; however, repeated transfers are associated with a high risk of musculoskeletal pain and injury, and training and education around transfers is minimal. The purpose of this study was to develop and assess the content validity of a new tool, the Caregiver Assisted Transfer Technique Instrument (CATT), which could be used to provide an objective indicator of transfer performance. Item importance, clarity, and appropriateness of responses were...
Source: Assistive Technology - April 26, 2024 Category: Rehabilitation Authors: Hailee R Kulich Diane Collins Brad E Dicianno Luci Leykum Lynn Worobey Rory Cooper Alicia M Koontz Source Type: research

Efficacy of local infiltration analgesia on recovery after total hip arthroplasty using direct anterior approach under spinal anaesthesia: a randomized, double-blind, placebo-controlled trial
Acta Orthop Belg. 2024 Mar;90(1):11-15. doi: 10.52628/90.1.12345.ABSTRACTThe utilization of local infiltration analgesia (LIA) is a common practice in total hip arthroplasty (THA) procedures to mitigate postoperative pain and diminish the necessity for opioids. However, contemporary literature reports conflicting results. Our working hypothesis was that LIA renders better postoperative VAS-scores and reduces the need for oral analgetics. We performed a randomized, double-blind, placebo-controlled trial aimed at examining the effectiveness of LIA in THA. A total of 90 patients were included for statistical analysis. Our pri...
Source: Acta Orthopaedica Belgica - April 26, 2024 Category: Orthopaedics Authors: S Biesemans B Schuermans E Voets H Feyen Source Type: research

Musculoskeletal morbidity in adults with spinal cord injuries: A nationwide cohort study
CONCLUSION: SCI increases the risk of MSK morbidity. Lumbar SCI is associated with a higher incidence and risk of MSK morbidity than are cervical or thoracic SCIs.PMID:38669487 | DOI:10.3233/NRE-230263 (Source: NeuroRehabilitation)
Source: NeuroRehabilitation - April 26, 2024 Category: Rehabilitation Authors: Youngoh Bae Hohyun Jung Nakyung Shin Masoud Rahmati Raphael Udeh Abdolreza Kazemi Yusheng Li Marco Solmi Muhammad Syafrudin Norma Latif Fitriyani Guillaume Fond Laurent Boyer Seung Won Lee Source Type: research

Opiate-reduction protocol for common outpatient spinal procedures: a long-term feasibility study and single-center experience
CONCLUSIONS: A standardized discharge protocol for postoperative outpatient spinal procedures can lead to long-term reductions in opioid discharge quantity, without compromising patient safety or increasing the utilization of hospital resources through readmissions, refill requests, or clinic phone calls. This study provides an example of a feasible and effective discharge prescription regimen that may be generalizable to common outpatient neurosurgical procedures with long-term evidence that a small intervention can lead to ongoing reduced quantities of postoperative opioids at the time of discharge.PMID:38669713 | DOI:10...
Source: Journal of Neurosurgery - April 26, 2024 Category: Neurosurgery Authors: Nicholas Eley Aiyush Bansal Murad Alostaz Rakesh Kumar Jean-Christophe Leveque Philip K Louie Source Type: research

Prevalence and associated factors of non-traumatic knee pain in high school volleyball players: a cross-sectional study
CONCLUSION: Factors associated with knee pain include a history of LBP and reduced flexibility on the heel-buttock distance test. The study highlights the need for a comprehensive approach, considering the coexistence of LBP and focusing on improving anterior thigh flexibility.PMID:38669135 | DOI:10.1080/00913847.2024.2348439 (Source: The Physician and Sportsmedicine Online)
Source: The Physician and Sportsmedicine Online - April 26, 2024 Category: Sports Medicine Authors: Yasuaki Mizoguchi Kenta Suzuki Naoki Shimada Hiroyuki Naka Toby Hall Kiyokazu Akasaka Source Type: research

Development and content validity of the caregiver assisted transfer technique instrument
Assist Technol. 2024 Apr 26:1-9. doi: 10.1080/10400435.2024.2336334. Online ahead of print.ABSTRACTInformal caregivers often provide transfer assistance to individuals with disabilities; however, repeated transfers are associated with a high risk of musculoskeletal pain and injury, and training and education around transfers is minimal. The purpose of this study was to develop and assess the content validity of a new tool, the Caregiver Assisted Transfer Technique Instrument (CATT), which could be used to provide an objective indicator of transfer performance. Item importance, clarity, and appropriateness of responses were...
Source: Assistive Technology - April 26, 2024 Category: Rehabilitation Authors: Hailee R Kulich Diane Collins Brad E Dicianno Luci Leykum Lynn Worobey Rory Cooper Alicia M Koontz Source Type: research

Analgesic Mechanism of Dexmedetomidine and Esketamine in Rats with Spinal Cord Injury
CONCLUSIONS: Treatment using DEX combined with ESK improves the motor function, inhibits inflammation and astrocyte activity, and exerts analgesic effects on rats with SCI. These findings can serve as a reference for the selection of multi-modal analgesics.PMID:38665020 | DOI:10.24976/Discov.Med.202436183.67 (Source: Discovery Medicine)
Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Huiting Zhao Zhuocheng Li Source Type: research

Efficacy of local infiltration analgesia on recovery after total hip arthroplasty using direct anterior approach under spinal anaesthesia: a randomized, double-blind, placebo-controlled trial
Acta Orthop Belg. 2024 Mar;90(1):11-15. doi: 10.52628/90.1.12345.ABSTRACTThe utilization of local infiltration analgesia (LIA) is a common practice in total hip arthroplasty (THA) procedures to mitigate postoperative pain and diminish the necessity for opioids. However, contemporary literature reports conflicting results. Our working hypothesis was that LIA renders better postoperative VAS-scores and reduces the need for oral analgetics. We performed a randomized, double-blind, placebo-controlled trial aimed at examining the effectiveness of LIA in THA. A total of 90 patients were included for statistical analysis. Our pri...
Source: Acta Orthopaedica Belgica - April 26, 2024 Category: Orthopaedics Authors: S Biesemans B Schuermans E Voets H Feyen Source Type: research

Long-term efficacy of microendoscopic laminotomy for lumbar spinal stenosis in advanced degenerative spondylolisthesis with or without dynamic spinal instability: a propensity score-matching analysis
CONCLUSIONS: MEL may have good long-term results in patients with DS without dynamic instability. Women with dynamic instability may require additional fusion surgery in approximately 25% of cases for a period of ≥ 5 years.PMID:38669704 | DOI:10.3171/2024.2.SPINE231075 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - April 26, 2024 Category: Neurosurgery Authors: Shizumasa Murata Keiji Nagata Hiroshi Iwasaki Hiroshi Hashizume Akihito Minamide Yukihiro Nakagawa Shunji Tsutsui Masanari Takami Yuyu Ishimoto Masatoshi Teraguchi Hiroki Iwahashi Kimihide Murakami Ryo Taiji Takuhei Kozaki Yoji Kitano Munehito Yoshida Hir Source Type: research