Letter to the Editor. Recurrent disc herniation and spinal instability
J Neurosurg Spine. 2021 Feb 26:1. doi: 10.3171/2020.12.SPINE202101. Online ahead of print.NO ABSTRACTPMID:33636698 | DOI:10.3171/2020.12.SPINE202101 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Atul Goel Source Type: research

Utility of prediction model score: a proposed tool to standardize the performance and generalizability of clinical predictive models based on systematic review
CONCLUSIONS: As interest in utilizing predictive analytics in spine surgery increases, there is a concomitant increase in the number of published prediction models that differ in methodology and performance. Prior to applying these models to patient care, these models must be evaluated. To begin addressing this issue, the authors proposed a grading system that compares these models based on various metrics related to their original design as well as internal and external validation. Ultimately, this may hopefully aid clinicians in determining the relative validity and usability of a given model.PMID:33636704 | DOI:10.3171/...
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Jeff Ehresman Daniel Lubelski Zach Pennington Bethany Hung A Karim Ahmed Tej D Azad Kurt Lehner James Feghali Zorica Buser James Harrop Jefferson Wilson Shekar Kurpad Zoher Ghogawala Daniel M Sciubba Source Type: research

Letter to the Editor. Recurrent disc herniation and spinal instability
J Neurosurg Spine. 2021 Feb 26:1. doi: 10.3171/2020.12.SPINE202101. Online ahead of print.NO ABSTRACTPMID:33636698 | DOI:10.3171/2020.12.SPINE202101 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Atul Goel Source Type: research

Utility of prediction model score: a proposed tool to standardize the performance and generalizability of clinical predictive models based on systematic review
CONCLUSIONS: As interest in utilizing predictive analytics in spine surgery increases, there is a concomitant increase in the number of published prediction models that differ in methodology and performance. Prior to applying these models to patient care, these models must be evaluated. To begin addressing this issue, the authors proposed a grading system that compares these models based on various metrics related to their original design as well as internal and external validation. Ultimately, this may hopefully aid clinicians in determining the relative validity and usability of a given model.PMID:33636704 | DOI:10.3171/...
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Jeff Ehresman Daniel Lubelski Zach Pennington Bethany Hung A Karim Ahmed Tej D Azad Kurt Lehner James Feghali Zorica Buser James Harrop Jefferson Wilson Shekar Kurpad Zoher Ghogawala Daniel M Sciubba Source Type: research

Letter to the Editor. Recurrent disc herniation and spinal instability
J Neurosurg Spine. 2021 Feb 26:1. doi: 10.3171/2020.12.SPINE202101. Online ahead of print.NO ABSTRACTPMID:33636698 | DOI:10.3171/2020.12.SPINE202101 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Atul Goel Source Type: research

Utility of prediction model score: a proposed tool to standardize the performance and generalizability of clinical predictive models based on systematic review
CONCLUSIONS: As interest in utilizing predictive analytics in spine surgery increases, there is a concomitant increase in the number of published prediction models that differ in methodology and performance. Prior to applying these models to patient care, these models must be evaluated. To begin addressing this issue, the authors proposed a grading system that compares these models based on various metrics related to their original design as well as internal and external validation. Ultimately, this may hopefully aid clinicians in determining the relative validity and usability of a given model.PMID:33636704 | DOI:10.3171/...
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Jeff Ehresman Daniel Lubelski Zach Pennington Bethany Hung A Karim Ahmed Tej D Azad Kurt Lehner James Feghali Zorica Buser James Harrop Jefferson Wilson Shekar Kurpad Zoher Ghogawala Daniel M Sciubba Source Type: research

Letter to the Editor. Recurrent disc herniation and spinal instability
J Neurosurg Spine. 2021 Feb 26:1. doi: 10.3171/2020.12.SPINE202101. Online ahead of print.NO ABSTRACTPMID:33636698 | DOI:10.3171/2020.12.SPINE202101 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Atul Goel Source Type: research

Utility of prediction model score: a proposed tool to standardize the performance and generalizability of clinical predictive models based on systematic review
CONCLUSIONS: As interest in utilizing predictive analytics in spine surgery increases, there is a concomitant increase in the number of published prediction models that differ in methodology and performance. Prior to applying these models to patient care, these models must be evaluated. To begin addressing this issue, the authors proposed a grading system that compares these models based on various metrics related to their original design as well as internal and external validation. Ultimately, this may hopefully aid clinicians in determining the relative validity and usability of a given model.PMID:33636704 | DOI:10.3171/...
Source: Journal of Neurosurgery.Spine - February 26, 2021 Category: Neurosurgery Authors: Jeff Ehresman Daniel Lubelski Zach Pennington Bethany Hung A Karim Ahmed Tej D Azad Kurt Lehner James Feghali Zorica Buser James Harrop Jefferson Wilson Shekar Kurpad Zoher Ghogawala Daniel M Sciubba Source Type: research

Impact of surgeon and hospital factors on surgical decision-making for grade 1 degenerative lumbar spondylolisthesis: a Quality Outcomes Database analysis
CONCLUSIONS: Nonteaching centers were more likely to perform decompressive laminectomy with supplemental fusion for spondylolisthesis. Suburban hospitals were more likely to perform decompression only. Surgeon characteristics were not found to influence treatment selection after adjustment for clinical covariates. Further large database registry experience from surgeons at high-volume academic centers at which surgically and medically complex patients are treated may provide additional insight into factors associated with treatment preference for degenerative spondylolisthesis.PMID:33607612 | DOI:10.3171/2020.8.SPINE201015...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Meng Huang Avery Buchholz Anshit Goyal Erica Bisson Zoher Ghogawala Eric Potts John Knightly Domagoj Coric Anthony Asher Kevin Foley Praveen V Mummaneni Paul Park Mark Shaffrey Kai-Ming Fu Jonathan Slotkin Steven Glassman Mohamad Bydon Michael Wang Source Type: research

Strategies for prevention of rod fracture in adult spinal deformity: cobalt chrome rod, accessory rod technique, and lateral lumbar interbody fusion
J Neurosurg Spine. 2021 Feb 19:1-10. doi: 10.3171/2020.8.SPINE201037. Online ahead of print.ABSTRACTOBJECTIVE: Restoring the proper sagittal alignment in adult spinal deformity (ASD) can improve radiological and clinical outcomes, but pseudarthrosis including rod fracture (RF) is a common problematic complication. The purpose of this study was to analyze the methods for reducing the incidence of RF in deformity correction of ASD.METHODS: The authors retrospectively selected 178 consecutive patients (mean age 70.8 years) with lumbar degenerative kyphosis (LDK) who underwent deformity correction with a minimum 2-year follow-...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Ki Young Lee Jung-Hee Lee Kyung-Chung Kang Sang-Kyu Im Hae Seong Lim Sun Whan Choi Source Type: research

Determining validity, discriminant ability, responsiveness, and minimal clinically important differences for PROMIS in adult spinal deformity
CONCLUSIONS: PROMIS is a valid assessment of patient health, can discriminate between disease severity levels, and shows responsiveness to changes after ASD surgery. The MCIDs provided herein may help clinicians interpret postoperative changes in PROMIS scores, taking into account the fact that they are pending external validation.PMID:33607619 | DOI:10.3171/2020.8.SPINE191551 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Alvaro Ibaseta Rafa Rahman Nicholas S Andrade Richard L Skolasky Khaled M Kebaish Daniel M Sciubba Brian J Neuman Source Type: research

Impact of surgeon and hospital factors on surgical decision-making for grade 1 degenerative lumbar spondylolisthesis: a Quality Outcomes Database analysis
CONCLUSIONS: Nonteaching centers were more likely to perform decompressive laminectomy with supplemental fusion for spondylolisthesis. Suburban hospitals were more likely to perform decompression only. Surgeon characteristics were not found to influence treatment selection after adjustment for clinical covariates. Further large database registry experience from surgeons at high-volume academic centers at which surgically and medically complex patients are treated may provide additional insight into factors associated with treatment preference for degenerative spondylolisthesis.PMID:33607612 | DOI:10.3171/2020.8.SPINE201015...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Meng Huang Avery Buchholz Anshit Goyal Erica Bisson Zoher Ghogawala Eric Potts John Knightly Domagoj Coric Anthony Asher Kevin Foley Praveen V Mummaneni Paul Park Mark Shaffrey Kai-Ming Fu Jonathan Slotkin Steven Glassman Mohamad Bydon Michael Wang Source Type: research

Strategies for prevention of rod fracture in adult spinal deformity: cobalt chrome rod, accessory rod technique, and lateral lumbar interbody fusion
J Neurosurg Spine. 2021 Feb 19:1-10. doi: 10.3171/2020.8.SPINE201037. Online ahead of print.ABSTRACTOBJECTIVE: Restoring the proper sagittal alignment in adult spinal deformity (ASD) can improve radiological and clinical outcomes, but pseudarthrosis including rod fracture (RF) is a common problematic complication. The purpose of this study was to analyze the methods for reducing the incidence of RF in deformity correction of ASD.METHODS: The authors retrospectively selected 178 consecutive patients (mean age 70.8 years) with lumbar degenerative kyphosis (LDK) who underwent deformity correction with a minimum 2-year follow-...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Ki Young Lee Jung-Hee Lee Kyung-Chung Kang Sang-Kyu Im Hae Seong Lim Sun Whan Choi Source Type: research

Determining validity, discriminant ability, responsiveness, and minimal clinically important differences for PROMIS in adult spinal deformity
CONCLUSIONS: PROMIS is a valid assessment of patient health, can discriminate between disease severity levels, and shows responsiveness to changes after ASD surgery. The MCIDs provided herein may help clinicians interpret postoperative changes in PROMIS scores, taking into account the fact that they are pending external validation.PMID:33607619 | DOI:10.3171/2020.8.SPINE191551 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Alvaro Ibaseta Rafa Rahman Nicholas S Andrade Richard L Skolasky Khaled M Kebaish Daniel M Sciubba Brian J Neuman Source Type: research

Impact of surgeon and hospital factors on surgical decision-making for grade 1 degenerative lumbar spondylolisthesis: a Quality Outcomes Database analysis
CONCLUSIONS: Nonteaching centers were more likely to perform decompressive laminectomy with supplemental fusion for spondylolisthesis. Suburban hospitals were more likely to perform decompression only. Surgeon characteristics were not found to influence treatment selection after adjustment for clinical covariates. Further large database registry experience from surgeons at high-volume academic centers at which surgically and medically complex patients are treated may provide additional insight into factors associated with treatment preference for degenerative spondylolisthesis.PMID:33607612 | DOI:10.3171/2020.8.SPINE201015...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Meng Huang Avery Buchholz Anshit Goyal Erica Bisson Zoher Ghogawala Eric Potts John Knightly Domagoj Coric Anthony Asher Kevin Foley Praveen V Mummaneni Paul Park Mark Shaffrey Kai-Ming Fu Jonathan Slotkin Steven Glassman Mohamad Bydon Michael Wang Source Type: research

Strategies for prevention of rod fracture in adult spinal deformity: cobalt chrome rod, accessory rod technique, and lateral lumbar interbody fusion
J Neurosurg Spine. 2021 Feb 19:1-10. doi: 10.3171/2020.8.SPINE201037. Online ahead of print.ABSTRACTOBJECTIVE: Restoring the proper sagittal alignment in adult spinal deformity (ASD) can improve radiological and clinical outcomes, but pseudarthrosis including rod fracture (RF) is a common problematic complication. The purpose of this study was to analyze the methods for reducing the incidence of RF in deformity correction of ASD.METHODS: The authors retrospectively selected 178 consecutive patients (mean age 70.8 years) with lumbar degenerative kyphosis (LDK) who underwent deformity correction with a minimum 2-year follow-...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Ki Young Lee Jung-Hee Lee Kyung-Chung Kang Sang-Kyu Im Hae Seong Lim Sun Whan Choi Source Type: research

Determining validity, discriminant ability, responsiveness, and minimal clinically important differences for PROMIS in adult spinal deformity
CONCLUSIONS: PROMIS is a valid assessment of patient health, can discriminate between disease severity levels, and shows responsiveness to changes after ASD surgery. The MCIDs provided herein may help clinicians interpret postoperative changes in PROMIS scores, taking into account the fact that they are pending external validation.PMID:33607619 | DOI:10.3171/2020.8.SPINE191551 (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Alvaro Ibaseta Rafa Rahman Nicholas S Andrade Richard L Skolasky Khaled M Kebaish Daniel M Sciubba Brian J Neuman Source Type: research

Impact of surgeon and hospital factors on surgical decision-making for grade 1 degenerative lumbar spondylolisthesis: a Quality Outcomes Database analysis.
CONCLUSIONS: Nonteaching centers were more likely to perform decompressive laminectomy with supplemental fusion for spondylolisthesis. Suburban hospitals were more likely to perform decompression only. Surgeon characteristics were not found to influence treatment selection after adjustment for clinical covariates. Further large database registry experience from surgeons at high-volume academic centers at which surgically and medically complex patients are treated may provide additional insight into factors associated with treatment preference for degenerative spondylolisthesis. PMID: 33607612 [PubMed - as supplied by ...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Huang M, Buchholz A, Goyal A, Bisson E, Ghogawala Z, Potts E, Knightly J, Coric D, Asher A, Foley K, Mummaneni PV, Park P, Shaffrey M, Fu KM, Slotkin J, Glassman S, Bydon M, Wang M Tags: J Neurosurg Spine Source Type: research

Strategies for prevention of rod fracture in adult spinal deformity: cobalt chrome rod, accessory rod technique, and lateral lumbar interbody fusion.
Abstract OBJECTIVE: Restoring the proper sagittal alignment in adult spinal deformity (ASD) can improve radiological and clinical outcomes, but pseudarthrosis including rod fracture (RF) is a common problematic complication. The purpose of this study was to analyze the methods for reducing the incidence of RF in deformity correction of ASD. METHODS: The authors retrospectively selected 178 consecutive patients (mean age 70.8 years) with lumbar degenerative kyphosis (LDK) who underwent deformity correction with a minimum 2-year follow-up. Patients were classified into the non-RF group (n = 131) and the RF grou...
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Lee KY, Lee JH, Kang KC, Im SK, Lim HS, Choi SW Tags: J Neurosurg Spine Source Type: research

Determining validity, discriminant ability, responsiveness, and minimal clinically important differences for PROMIS in adult spinal deformity.
CONCLUSIONS: PROMIS is a valid assessment of patient health, can discriminate between disease severity levels, and shows responsiveness to changes after ASD surgery. The MCIDs provided herein may help clinicians interpret postoperative changes in PROMIS scores, taking into account the fact that they are pending external validation. PMID: 33607619 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 19, 2021 Category: Neurosurgery Authors: Ibaseta A, Rahman R, Andrade NS, Skolasky RL, Kebaish KM, Sciubba DM, Neuman BJ Tags: J Neurosurg Spine Source Type: research

Letter to the Editor. Metastatic spine disease and outcome predictions.
PMID: 33578385 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 12, 2021 Category: Neurosurgery Authors: Amelot A, Terrier LM, Cook AR, Borius PY, Mathon B Tags: J Neurosurg Spine Source Type: research

Surgical outcomes in rigid versus flexible cervical deformities.
Abstract OBJECTIVE: Cervical deformity (CD) patients have severe disability and poor health status. However, little is known about how patients with rigid CD compare with those with flexible CD. The main objectives of this study were to 1) assess whether patients with rigid CD have worse baseline alignment and therefore require more aggressive surgical corrections and 2) determine whether patients with rigid CD have similar postoperative outcomes as those with flexible CD. METHODS: This is a retrospective review of a prospective, multicenter CD database. Rigid CD was defined as cervical lordosis (CL) change
Source: Journal of Neurosurgery.Spine - February 12, 2021 Category: Neurosurgery Authors: Protopsaltis TS, Stekas N, Smith JS, Soroceanu A, Lafage R, Daniels AH, Kim HJ, Passias PG, Mundis GM, Klineberg EO, Hamilton DK, Gupta M, Lafage V, Hart RA, Schwab F, Burton DC, Bess S, Shaffrey CI, Ames CP Tags: J Neurosurg Spine Source Type: research

Association of extended duration of sciatic leg pain with worse outcome after lumbar disc herniation surgery: a register study in 6216 patients.
Abstract OBJECTIVE: Sciatica is the hallmark symptom of a lumbar disc herniation (LDH). Up to 90% of LDH patients recover within 12 weeks regardless of treatment. With continued deteriorating symptoms and low patient quality of life, most surgeons recommend surgical discectomy. However, there is not yet a clear consensus regarding the proper timing of surgery. The aim of this study was to evaluate how the duration of preoperative leg pain (sciatic neuralgia) is associated with patient-reported levels of postoperative leg pain reduction and other patient-reported outcome measures (PROMs) in a prospectively collecte...
Source: Journal of Neurosurgery.Spine - February 12, 2021 Category: Neurosurgery Authors: Beck J, Westin O, Brisby H, Baranto A Tags: J Neurosurg Spine Source Type: research

Report of a spinal extradural arteriovenous fistula with double radiculomedullary venous drainage: therapeutic implications and role of intraoperative spinal angiography.
Abstract Low-flow spinal extradural arteriovenous fistulas (SEAVFs) are frequently misdiagnosed as spinal dural arteriovenous fistulas (SDAVFs), and their true prevalence is unknown. The principal feature distinguishing low-flow SEAVFs from SDAVFs is the location of the shunt, which involves a pouch of epidural plexus in SEAVFs and a radiculomedullary vein (RMV) in SDAVFs. A venous hypertensive myelopathy comparable to the one observed with SDAVFs develops when the arterialized venous pouch of an SEAVF is connected to an RMV. Depending on the size of the epidural pouch, a low-flow SEAVF may uncommonly drain into m...
Source: Journal of Neurosurgery.Spine - February 5, 2021 Category: Neurosurgery Authors: Xu R, Gregg L, Larry Lo SF, Gailloud P Tags: J Neurosurg Spine Source Type: research

A study of probable benefit of a bioresorbable polymer scaffold for safety and neurological recovery in patients with complete thoracic spinal cord injury: 6-month results from the INSPIRE study.
CONCLUSIONS: In this first-in-human study, implantation of the NSS within the spinal cord appeared to be safe in the setting of surgical decompression and stabilization for complete (AIS grade A) thoracic SCI. It was associated with a 6-month AIS grade conversion rate that exceeded historical controls. The INSPIRE study data demonstrate that the potential benefits of the NSS outweigh the risks in this patient population and support further clinical investigation in a randomized controlled trial.Clinical trial registration no.: NCT02138110 (clinicaltrials.gov). PMID: 33545674 [PubMed - as supplied by publisher] (Source...
Source: Journal of Neurosurgery.Spine - February 5, 2021 Category: Neurosurgery Authors: Kim KD, Lee KS, Coric D, Chang JJ, Harrop JS, Theodore N, Toselli RM Tags: J Neurosurg Spine Source Type: research

Simultaneous translation on two rods improves the correction and apex translocation in adolescent patients with hypokyphotic scoliosis.
The objectives of this study were to apply the simultaneous translation on two rods (ST2R) maneuver involving rods contoured with a convexity at the desired thoracic kyphosis (TK) apex level and to assess the effects on the ability to support triplanar deformity corrections, including TK apex improvement, in patients with hypokyphotic adolescent idiopathic scoliosis (AIS). METHODS: Using retrospective analysis, the authors examined the digital records that included 2- to 4-week, 1-year, and 2-year postoperative radiographic follow-up data of female hypokyphotic (TK
Source: Journal of Neurosurgery.Spine - February 5, 2021 Category: Neurosurgery Authors: Sakai D, Schol J, Hiyama A, Katoh H, Tanaka M, Sato M, Watanabe M Tags: J Neurosurg Spine Source Type: research

Letter to the Editor. Randomized controlled trials on anterior versus posterior surgical decompression for degenerative cervical myelopathy.
PMID: 33545676 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 5, 2021 Category: Neurosurgery Authors: Ganau M, Iqbal M, Ligarotti GKI, Kato S Tags: J Neurosurg Spine Source Type: research

Impact of dual-headed pedicle screws on the biomechanics of lumbosacral junction multirod constructs.
CONCLUSIONS: RS across the lumbosacral junction can be high. Supplemental rod fixation with DTH is an effective strategy for reducing RS across the lumbosacral junction. However, the greatest reduction in RS and SM was achieved with a VAC that allowed for straight (uncontoured) accessory rod placement. PMID: 33545680 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 5, 2021 Category: Neurosurgery Authors: Godzik J, de Andrada Pereira B, Sawa AGU, Lehrman JN, Hlubek RJ, Kelly BP, Turner JD Tags: J Neurosurg Spine Source Type: research

Reintervention rate of arachnolysis versus shunting for nonforaminal syringomyelia.
CONCLUSIONS: Arachnolysis led to fewer reinterventions than shunting in patients with nonforaminal syringomyelia. There was a high risk of reintervention for patients with extensive arachnopathies, irrespective of the surgical technique. PMID: 33545681 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 5, 2021 Category: Neurosurgery Authors: Guillaumet G, Aghakhani N, Morar S, Copaciu R, Parker F, Knafo S Tags: J Neurosurg Spine Source Type: research

A randomized controlled trial of the X-Stop interspinous distractor device versus laminectomy for lumbar spinal stenosis with 2-year quality-of-life and cost-effectiveness outcomes.
CONCLUSIONS: Laminectomy was more cost-effective than the X-Stop for the treatment of LSS, primarily due to device cost. The X-Stop device led to an improvement in QOL, but it was less than that in the laminectomy group. The use of the X-Stop IDD should be reserved for cases in which a less-invasive procedure is required. There is no justification for its regular use as an alternative to decompressive surgery.Clinical trial registration no.: ISRCTN88702314 (www.isrctn.com). PMID: 33530059 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 2, 2021 Category: Neurosurgery Authors: Borg A, Hill CS, Nurboja B, Critchley G, Choi D Tags: J Neurosurg Spine Source Type: research

Editorial. Interspinous spacers for lumbar stenosis: time for obsolescence?
PMID: 33530060 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - February 2, 2021 Category: Neurosurgery Authors: Wang MC, AlGhamdi MYT Tags: J Neurosurg Spine Source Type: research

Patient-specific prediction model for clinical and quality-of-life outcomes after lumbar spine surgery.
CONCLUSIONS: The prediction tools derived from this study constitute important adjuncts to clinical decision-making that can offer patients undergoing lumbar spine surgery realistic and personalized expectations of postoperative outcome. They may also aid physicians in surgical planning, referrals, and counseling to ultimately lead to improved patient experience and outcomes. ABBREVIATIONS: ABBREVIATIONS ALIF = anterior lumbar interbody fusion; AUC = area under the curve; BMI = body mass index; CCI = Charlson Comorbidity Index; c index = concordance index; ED = emergency department; EQ-5D = EuroQOL-5D; MCID = minimum ...
Source: Journal of Neurosurgery.Spine - January 29, 2021 Category: Neurosurgery Authors: Lubelski D, Feghali J, Nowacki AS, Alentado VJ, Planchard R, Abdullah KG, Sciubba DM, Steinmetz MP, Benzel EC, Mroz TE Tags: J Neurosurg Spine Source Type: research

Survival, fusion, and hardware failure after surgery for spinal metastatic disease.
CONCLUSIONS: Low rates of complete fusion and hardware failure were observed due to the high competing risk of death. Further prospective, case-control studies incorporating nonfusion instrumentation techniques may be warranted. PMID: 33513569 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - January 29, 2021 Category: Neurosurgery Authors: Yee TJ, Saadeh YS, Strong MJ, Ward AL, Elswick CM, Srinivasan S, Park P, Oppenlander ME, Spratt DE, Jackson WC, Szerlip NJ Tags: J Neurosurg Spine Source Type: research

Cerebrospinal fluid biomarkers of glial and axonal injury in cervical spondylotic myelopathy.
d N Abstract OBJECTIVE: Degenerative cervical spondylotic myelopathy (CSM) is a major cause of spinal cord dysfunction with an unpredictable prognosis. Βiomarkers reflecting pathophysiological processes in CSM have been insufficiently investigated. It was hypothesized that preoperative cerebrospinal fluid (CSF) biomarker levels are altered in patients with CSM and correlate with neurological status and outcome. METHODS: CSF biomarkers from patients with CSM and controls were analyzed with immunoassays. Spinal cord changes were evaluated with MRI. The American Spinal Cord Injury Association Impairment Sca...
Source: Journal of Neurosurgery.Spine - January 29, 2021 Category: Neurosurgery Authors: Tsitsopoulos PP, Holmström U, Blennow K, Zetterberg H, Marklund N Tags: J Neurosurg Spine Source Type: research

Letter to the Editor. Suggested addition to the classification system for multirod constructs.
PMID: 33482634 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - January 22, 2021 Category: Neurosurgery Authors: Khan A, Pollina J, Mullin JP Tags: J Neurosurg Spine Source Type: research

Institutional review of the management of type II odontoid fractures: associations and outcomes with fibrous union.
CONCLUSIONS: The authors delineate the validity of upright cervical radiographs on presentation in association with follow-up stability in type II odontoid fractures. In their experience, factors associated with instability included cervical myelopathy, cerebrovascular disease, and fracture displacement but not increased age. Operatively managed patients had higher complication rates than those managed without surgery. Fibrous union, which can occur with nonoperative management, provided adequate stability. PMID: 33482645 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - January 22, 2021 Category: Neurosurgery Authors: Wilson C, Hoyos M, Huh A, Priddy B, Avila S, Mendenhall S, Anokwute MC, Eckert GJ, Stockwell DW Tags: J Neurosurg Spine Source Type: research

Clinical and radiological results of indirect decompression after anterior lumbar interbody fusion in central spinal canal stenosis.
In this report, along with the many advantages of the anterior approach, the authors share cases with good outcomes that they have encountered. METHODS: The authors performed a retrospective analysis of 64 consecutive patients who underwent ALIF for central spinal canal stenosis with instability and mixed foraminal stenosis between January 2015 and December 2018 at their hospital. Clinical assessments were performed using the visual analog scale score, the Oswestry Disability Index, and the modified Macnab criteria. The radiographic parameters were determined from pre- and postoperative cross-sectional MRI scans of th...
Source: Journal of Neurosurgery.Spine - January 15, 2021 Category: Neurosurgery Authors: Lee DH, Lee DG, Hwang JS, Jang JW, Maeng DH, Park CK Tags: J Neurosurg Spine Source Type: research

Change in pelvic incidence between the supine and standing positions in patients with bilateral sacroiliac joint vacuum signs.
The objective of this study was to determine if patients with SI joint vacuum sign have a change in PI between the supine and standing positions. METHODS: A retrospective chart review identified patients with a standing radiograph, supine radiograph, and CT scan encompassing the SI joints within a 6-month period. Patients were grouped according to their SI joints having either no vacuum sign, unilateral vacuum sign, or bilateral vacuum sign. PI was measured by two independent reviewers. RESULTS: Seventy-three patients were identified with an average age of 66 years and a BMI of 30 kg/m2. Patients with bilateral S...
Source: Journal of Neurosurgery.Spine - January 15, 2021 Category: Neurosurgery Authors: Mikula AL, Fogelson JL, Oushy S, Pinter ZW, Peters PA, Abode-Iyamah K, Sebastian AS, Freedman B, Currier BL, Polly DW, Elder BD Tags: J Neurosurg Spine Source Type: research

Microendoscopic decompression for lumbar spinal stenosis caused by facet-joint cysts: a novel technique with a cyst-dyeing protocol and cohort comparison study.
CONCLUSIONS: In this study, the authors demonstrated that the clinical outcomes of microendoscopic spinal decompression in patients with LSS or LFS caused by facet-joint cysts are generally favorable. Additionally, the adjunctive cyst-dyeing method effectively delineated the cystic and dural boundaries, facilitating safer and more effective cyst separation and neural decompression. Microendoscopic surgery combined with this novel facet cyst-dyeing method is a safe and effective minimally invasive technique for facet-joint cysts. PMID: 33450739 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - January 15, 2021 Category: Neurosurgery Authors: Murata S, Minamide A, Takami M, Iwasaki H, Okada S, Nonaka K, Taneichi H, Schoenfeld AJ, Simpson AK, Yamada H Tags: J Neurosurg Spine Source Type: research

Radiologic prognostic factors of curve progression in early degenerative lumbar scoliosis.
In this study the authors aimed to determine the risk factors associated with curve progression in early DLS. METHODS: Fifty-one patients with early DLS and Cobb angles of 5°-15° were investigated. In total, 7 men and 44 women (mean age 61.6 years) were observed for a mean period of 13.7 years. The subjects were divided into two groups according to Cobb angle progression (≥ 15° or
Source: Journal of Neurosurgery.Spine - January 15, 2021 Category: Neurosurgery Authors: Park JS, Park SJ, Lee CS, Yum TH, Kim BT Tags: J Neurosurg Spine Source Type: research

Association of intravenous administration of human Muse cells with deficit amelioration in a rat model of spinal cord injury.
CONCLUSIONS: Following SCI, Muse cells in CL2020 can reach the injured spinal cord after intravenous administration and differentiate into neuronal cells. Muse cells in CL2020 facilitated nerve fiber preservation and exerted therapeutic potential for severe SCI. PMID: 33385996 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - January 1, 2021 Category: Neurosurgery Authors: Kajitani T, Endo T, Iwabuchi N, Inoue T, Takahashi Y, Abe T, Niizuma K, Tominaga T Tags: J Neurosurg Spine Source Type: research

Cauda equina syndrome secondary to portal vein thrombosis: case report of favorable outcome with conservative treatment.
Abstract Epidural varicosis is a rare though well-known cause of cauda equina syndrome (CES). Although inferior vena cava (IVC) obstruction is the most common finding in such cases, portal vein hypertension can lead to epidural venous plexus engorgement by means of lumbar portocaval shunt activation.A 40-year-old woman presented with right-sided sciatica, which progressed to right foot drop and a 3-day history of vesical tenesmus and fecal retention. She was initially diagnosed with L4-5 lumbar disc protrusion. However, contrast-enhanced lumbar MRI scan showed the presence of epidural varices in the L3-S1 tract. G...
Source: Journal of Neurosurgery.Spine - January 1, 2021 Category: Neurosurgery Authors: Campione A, Agresta G, Locatelli D, Pozzi F Tags: J Neurosurg Spine Source Type: research

Experience with an Enhanced Recovery After Spine Surgery protocol at an academic community hospital.
Abstract OBJECTIVE: Enhanced Recovery After Surgery (ERAS) protocols have rapidly gained popularity in multiple surgical specialties and are recognized for their potential to improve patient outcomes and decrease hospitalization costs. However, they have only recently been applied to spinal surgery. The goal in the present work was to describe the development, implementation, and impact of an Enhanced Recovery After Spine Surgery (ERASS) protocol for patients undergoing elective spine procedures at an academic community hospital. METHODS: A multidisciplinary team, drawing on prior publications and spine surge...
Source: Journal of Neurosurgery.Spine - December 25, 2020 Category: Neurosurgery Authors: Young R, Cottrill E, Pennington Z, Ehresman J, Ahmed AK, Kim T, Jiang B, Lubelski D, Zhu AM, Wright KS, Gavin D, Russo A, Hanna MN, Bydon A, Witham TF, Zygourakis C, Theodore N Tags: J Neurosurg Spine Source Type: research

Can we use shorter constructs while maintaining satisfactory sagittal plane alignment for adult spinal deformity?
CONCLUSIONS: In terms of subtypes of ASD in which lumbar kyphosis is the main deformity, if the PI is
Source: Journal of Neurosurgery.Spine - December 25, 2020 Category: Neurosurgery Authors: Moridaira H, Inami S, Takeuchi D, Ueda H, Aoki H, Imura T, Taneichi H Tags: J Neurosurg Spine Source Type: research

Posterior-only versus combined anterior-posterior fusion in Scheuermann disease: a systematic review and meta-analysis.
CONCLUSIONS: PO surgery using posterior osteotomies can achieve correction of Scheuermann kyphosis as successfully as AP surgery does. Reflecting the advancement of surgical technology, large prospective studies are necessary to identify the proper treatments for Scheuermann kyphosis. PMID: 33361485 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - December 25, 2020 Category: Neurosurgery Authors: Lee CH, Won YI, San Ko Y, Yang SH, Kim CH, Park SB, Chung CK Tags: J Neurosurg Spine Source Type: research

Long-term quality of life and work status after high-dose spinal cord stimulation in patients with failed back surgery syndrome: a secondary analysis of real-world data.
CONCLUSIONS: HD-SCS may lead to significantly increased HRQOL at 12 months in patients with FBSS. Despite the increase, reaching the HRQOL level of matched controls was not achieved. Only a limited number of patients were able to return to work. This finding indicates that specialized programs to enhance return to work may be beneficial for patients undergoing SCS. PMID: 33338990 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - December 18, 2020 Category: Neurosurgery Authors: Goudman L, De Smedt A, Putman K, Moens M, Discover Consortium Tags: J Neurosurg Spine Source Type: research

Predicting postoperative quality-of-life outcomes in patients with metastatic spine disease: who benefits?
Abstract Symptomatic spinal metastasis occurs in around 10% of all cancer patients, 5%-10% of whom will require operative management. While postoperative survival has been extensively evaluated, postoperative health-related quality-of-life (HRQOL) outcomes have remained relatively understudied. Available tools that measure HRQOL are heterogeneous and may emphasize different aspects of HRQOL. The authors of this paper recommend the use of the EQ-5D and Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ), given their extensive validation, to capture the QOL effects of systemic disease and spine metastases. Re...
Source: Journal of Neurosurgery.Spine - December 18, 2020 Category: Neurosurgery Authors: Feghali J, Pennington Z, Ehresman J, Lubelski D, Cottrill E, Ahmed AK, Schilling A, Sciubba DM Tags: J Neurosurg Spine Source Type: research

Long-term benefits of appropriately corrected sagittal alignment in reconstructive surgery for adult spinal deformity: evaluation of clinical outcomes and mechanical failures.
CONCLUSIONS: The clinical benefits from appropriate correction of sagittal alignment continued for a mean of 90.3 months. However, the intergroup difference in clinical outcomes between groups A and IA decreased over time. The development of rod fracture or PJK was not affected by the appropriateness of sagittal alignment. PMID: 33338999 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - December 18, 2020 Category: Neurosurgery Authors: Lee CS, Park JS, Nam Y, Choi YT, Park SJ Tags: J Neurosurg Spine Source Type: research

The association between patient rating of their spine surgeon and quality of postoperative outcome.
CONCLUSIONS: The authors found that after adjusting for patient-level covariates such as age, diagnosis of disc displacement, self-reported mental health, self-reported overall health, and preoperative patient-reported outcome measure status, a significant association was observed between top-box overall provider rating and 1-year improvement in VAS-BP, but no such association was observed for PROMIS-GH-PH and PROMIS-GH-MH. This suggests that pain-related outcome measures may serve as better predictors of patients' satisfaction with their spine surgeons. Furthermore, this suggests that the current method by which patient s...
Source: Journal of Neurosurgery.Spine - December 18, 2020 Category: Neurosurgery Authors: Rabah NM, Khan HA, Levin JM, Winkelman RD, Mroz TE, Steinmetz MP Tags: J Neurosurg Spine Source Type: research

"Houston, we have a problem": the difficulty of measuring outcomes in spinal surgery.
"Houston, we have a problem": the difficulty of measuring outcomes in spinal surgery. J Neurosurg Spine. 2020 Dec 18;:1-3 Authors: Basil GW, Sprau AC, Ghogawala Z, Yoon JW, Wang MY PMID: 33339001 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)
Source: Journal of Neurosurgery.Spine - December 18, 2020 Category: Neurosurgery Authors: Basil GW, Sprau AC, Ghogawala Z, Yoon JW, Wang MY Tags: J Neurosurg Spine Source Type: research