< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research
< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research
< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research
< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research
< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research
< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research
Astragalus polysaccharide promotes autophagy and alleviates diabetic nephropathy by targeting the lncRNA Gm41268/PRLR pathway
CONCLUSIONS: In summary, we demonstrated that the therapeutic effect of APS on DN is mediated via the Gm41268/PRLR pathway. This information contributes to the exploration of bioactive constituents in Chinese herbs as potential treatments for DN.PMID:37994436 | DOI:10.1080/0886022X.2023.2284211 (Source: Renal Failure)
Source: Renal Failure - November 23, 2023 Category: Urology & Nephrology Authors: Zedong Chen Huiyu Liang Xianxin Yan Qiuer Liang Zhenyu Bai Ting Xie Jiaojiao Dai Xiaoshan Zhao Ya Xiao Source Type: research
Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF ‐1 pathway
ConclusionAPC ameliorates IR in HepG2 cells through activating the STAT5/IGF-1 pathway. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - November 22, 2023 Category: Allergy & Immunology Authors: Xinxin Yue,
Wei Hao,
Min Wang,
Yang Fu Tags: ORIGINAL ARTICLE Source Type: research
Combined Astragalus, vitamin C, and vitamin E alleviate DEHP-induced oxidative stress and the decreased of insulin synthesis and secretion in INS-1 cells
In this study, we investigated the potential mechanisms of DEHP-induced diabetes mellitus through transcriptome analysis and vitro experiments using rat insulinoma cells (INS-1 cells). Furthermore, we explored the protection of the combined Astragalus, vitamin C, and vitamin E on DEHP-induced diabetes mellitus through these mechanisms. INS-1 cells in the logarithmic growth period were exposed to 125 umol/L DEHP followed by high-throughput sequencing analysis. The cell proliferation inhibition rate was determined using MTT assay for each group, and the cell apoptosis rate and intracellular ROS level were measured using flow...
Source: Cancer Control - November 20, 2023 Category: Cancer & Oncology Authors: Long Zhao Jianheng Zheng Jin Qin Xin Xu Xinyuan Liu Shuyu Yang Shuguang Li Bo Chen Jun Du Ruihua Dong Source Type: research
Combined Astragalus, vitamin C, and vitamin E alleviate DEHP-induced oxidative stress and the decreased of insulin synthesis and secretion in INS-1 cells
In this study, we investigated the potential mechanisms of DEHP-induced diabetes mellitus through transcriptome analysis and vitro experiments using rat insulinoma cells (INS-1 cells). Furthermore, we explored the protection of the combined Astragalus, vitamin C, and vitamin E on DEHP-induced diabetes mellitus through these mechanisms. INS-1 cells in the logarithmic growth period were exposed to 125 umol/L DEHP followed by high-throughput sequencing analysis. The cell proliferation inhibition rate was determined using MTT assay for each group, and the cell apoptosis rate and intracellular ROS level were measured using flow...
Source: Ecotoxicology and Environmental Safety - November 20, 2023 Category: Environmental Health Authors: Long Zhao Jianheng Zheng Jin Qin Xin Xu Xinyuan Liu Shuyu Yang Shuguang Li Bo Chen Jun Du Ruihua Dong Source Type: research
Total Astragalus saponins can reverse type 2 diabetes mellitus-related intestinal dysbiosis and hepatic insulin resistance in vivo
ConclusionTAS can ameliorate T2DM-related abnormal glucose and blood lipid metabolism, intestinal dysbiosis, and IR. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - November 20, 2023 Category: Endocrinology Source Type: research
Correction: Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B/mammalian target of rapamycin/glucose transporter 2 pathway
(Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - November 20, 2023 Category: Complementary Medicine Authors: Xiaodan Ren, Ying Dai, Mengya Shan, Jing Zheng, Zhongyi Zhang and Tao Shen Tags: Correction Source Type: research
