Identification of Novel Hub Genes Associated with Inflammation and Autophagy in Astragaloside Membranaceus ameliorates Lupus Nephritis by Bioinformatics Analysis and Molecular Dynamics Simulation
CONCLUSION: IL-1β, CASP3, STAT1, and PPARγ could be potential biomarkers and therapeutic targets in AM ameliorates LN.PMID:38299290 | DOI:10.2174/0113862073255980231113071412 (Source: Combinatorial Chemistry and High Throughput Screening)
Source: Combinatorial Chemistry and High Throughput Screening - February 1, 2024 Category: Chemistry Authors: Kaili Kong Xiaomei Qiao Ting Liu Xiaoxia Wang Rui Li Jingai Fang Xiaodong Zhang Source Type: research

Fabrication, characterization  and wound-healing properties of core–shell SF@chitosan/ZnO/Astragalus arbusculinus gum nanofibers
Nanomedicine, Ahead of Print. (Source: Future Medicine: Nanomedicine)
Source: Future Medicine: Nanomedicine - January 31, 2024 Category: Nanotechnology Authors: Zahra Amiri Amir Mahdi Molavi Amir Amani Kurosh Hamzanlui Moqadam Mehran Vatanchian Seyyed Ahmad Hashemi Fatemeh Oroojalian Source Type: research

Fabrication, characterization  and wound-healing properties of core–shell SF@chitosan/ZnO/Astragalus arbusculinus gum nanofibers
Nanomedicine, Ahead of Print. (Source: Nanomedicine)
Source: Nanomedicine - January 31, 2024 Category: Nanotechnology Authors: Zahra Amiri Amir Mahdi Molavi Amir Amani Kurosh Hamzanlui Moqadam Mehran Vatanchian Seyyed Ahmad Hashemi Fatemeh Oroojalian Source Type: research

Calycosin ameliorates osteoarthritis by regulating the imbalance between chondrocyte synthesis and catabolism
Osteoarthritis (OA) is a severe chronic inflammatory disease. As the main active component of Astragalus mongholicus Bunge, a classic traditional ethnic herb, calycosin exhibits anti-inflammatory action and its m... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - January 22, 2024 Category: Complementary Medicine Authors: Hong Su, Qiuju Yan, Wei Du, En Hu, Zhaoyu Yang, Wei Zhang, Yusheng Li, Tao Tang, Shushan Zhao and Yang Wang Tags: Research Source Type: research

Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis
Conclusion: This systematic review and meta-analysis revealed that the combination therapy of A. membranaceus with CT has more advantages than CT alone in improving LVR and clinical efficacy in HFrEF patients, without increasing the incidence of adverse reactions. However, due to the limited quality of included studies, more high-quality investigations are required to provide reliable evidence for clinical use.Systematic Review Registration:https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=397571, Identifier: CRD42023397571. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - January 12, 2024 Category: Drugs & Pharmacology Source Type: research

Cycloastragenol restrains keratinocyte hyperproliferation by promoting autophagy via the miR-145/STC1/Notch1 axis in psoriasis
CONCLUSION: CAG alleviated keratinocyte hyperproliferation through autophagy enhancement via regulating the miR-145/STC1/Notch1 axis in psoriasis.PMID:38194243 | DOI:10.1080/08923973.2023.2300310 (Source: Immunopharmacology and Immunotoxicology)
Source: Immunopharmacology and Immunotoxicology - January 9, 2024 Category: Allergy & Immunology Authors: Jie Xia Yuan Zhang Qing Wang Teng Zhang Source Type: research

Enhancing the Antiviral Potential and Anti-inflammatory Properties of Astragalus membranaceus: A Comprehensive Review
(Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry)
Source: Anti-Inflammatory and Anti-Allergy Agents in Medicinal Chemistry - January 4, 2024 Category: Allergy & Immunology Authors: Ghabeshi, Soad Mousavizadeh, Leila Ghasemi, Sorayya Tags: Review article Source Type: research

Arbuscular mycorrhizal fungal communities in soils where astragalus had grown for 2 years were similar to those in the abandoned farmland
ConclusionAmong the interannual soils, the 2-year soil may be more suitable for A. sinensis seedling rotation. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - January 4, 2024 Category: Microbiology Source Type: research

Green Synthesis, Characterization, and Antileishmanial Activity of the Silver Nanoparticles Alone and Along with Meglumine Antimoniate against < em > Leishmania major < /em > Infection
CONCLUSION: We found satisfactory findings in the parasite reduction in both in vitro and animal models. Still, more studies are expected to explain the precise action mechanisms of AgNPs and their efficacy in humans.PMID:38169555 | PMC:PMC10758081 | DOI:10.18502/ijpa.v18i4.14262 (Source: Iranian Journal of Parasitology)
Source: Iranian Journal of Parasitology - January 3, 2024 Category: Parasitology Authors: Qais Ahmed Majeed Abdullah Faisal Shater Abdullah Daria Alanazi Source Type: research