PLC1 mediated Cycloastragenol-induced stomatal movement by regulating the production of NO in Arabidopsis thaliana
Astragalus grows mainly in drought areas. Cycloastragenol (CAG) is a tetracyclic triterpenoid allelochemical extracted from traditional Chinese medicine Astragalus root. Phospholipase C (PLC) and G α-submit of the... (Source: BMC Plant Biology)
Source: BMC Plant Biology - November 17, 2023 Category: Biology Authors: Juantao Kong, Rongshan Chen, Ruirui Liu, Wei Wang, Simin Wang, Jinping Zhang and Ning Yang Tags: Research Source Type: research
Astragalus (Astragalus mongholicus) Improves Ventricular Remodeling via ESR1 Downregulation RhoA/ROCK Pathway
This study aims to investigate the effect of Astragalus on ventricular remodeling in ovariectomized spontaneous hypertensive rats (OVX-SHR).Female SHR/NCrl rats were subjected to bilateral ovariectomy to establish the OVX-SHR model and treated with Astragalus extract by gavage. The hemodynamics and cardiac function parameters were measured. HE and Masson staining were used to detect the pathological structure of myocardial remodeling and observe the hyperplasia of myocardial collagen fibers. The immunohistochemistry tested the level of α-SMA. The expression levels of inflammatory cytokines, IκB, p65, Cleaved-Caspase3, Rh...
Source: International Heart Journal - November 15, 2023 Category: Cardiology Authors: Hualei Dai Siming Tao Yingxia Guan Yijian Zhang Zhigang Yang Ji Jia Xinjin Zhang Guimin Zhang Source Type: research
Astragalus (Astragalus mongholicus) Improves Ventricular Remodeling via ESR1 Downregulation RhoA/ROCK Pathway
This study aims to investigate the effect of Astragalus on ventricular remodeling in ovariectomized spontaneous hypertensive rats (OVX-SHR).Female SHR/NCrl rats were subjected to bilateral ovariectomy to establish the OVX-SHR model and treated with Astragalus extract by gavage. The hemodynamics and cardiac function parameters were measured. HE and Masson staining were used to detect the pathological structure of myocardial remodeling and observe the hyperplasia of myocardial collagen fibers. The immunohistochemistry tested the level of α-SMA. The expression levels of inflammatory cytokines, IκB, p65, Cleaved-Caspase3, Rh...
Source: International Heart Journal - November 15, 2023 Category: Cardiology Authors: Hualei Dai Siming Tao Yingxia Guan Yijian Zhang Zhigang Yang Ji Jia Xinjin Zhang Guimin Zhang Source Type: research
A new acylated flavonol triglycoside and evaluation of the antioxidant activity of < em > Astragalus armatus < /em > subsp. < em > numidicus < /em > (Murb.) Emb. & amp; Maire
Nat Prod Res. 2023 Nov 11:1-6. doi: 10.1080/14786419.2023.2278761. Online ahead of print.ABSTRACTA new acylated flavonol triglycoside, quercetin-3-O-(5'-p-hydroxybenzoyl)-β-D-apiofuranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranoside (1), was isolated from the aerial parts of Astragalus armatus subsp. numidicus (Murb.) Emb. & Maire as well as ten known compounds, one phenolic compound, one flavonol-aglycone and eight flavonol-glycosides distributed into two monoglycosides, three diglycosides and three triosides. Their structures were mainly determined by 1D- and 2D-NMR experiments (1H,13C, COSY, HSQC, ...
Source: Natural Product Research - November 11, 2023 Category: Biochemistry Authors: Assia Khalfallah Zahia Kabouche Ahmed Kabouche Djemaa Berrehal Naima Boutaghane Laurence Voutquenne-Nazabadioko Source Type: research
A new acylated flavonol triglycoside and evaluation of the antioxidant activity of < em > Astragalus armatus < /em > subsp. < em > numidicus < /em > (Murb.) Emb. & amp; Maire
Nat Prod Res. 2023 Nov 11:1-6. doi: 10.1080/14786419.2023.2278761. Online ahead of print.ABSTRACTA new acylated flavonol triglycoside, quercetin-3-O-(5'-p-hydroxybenzoyl)-β-D-apiofuranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-galactopyranoside (1), was isolated from the aerial parts of Astragalus armatus subsp. numidicus (Murb.) Emb. & Maire as well as ten known compounds, one phenolic compound, one flavonol-aglycone and eight flavonol-glycosides distributed into two monoglycosides, three diglycosides and three triosides. Their structures were mainly determined by 1D- and 2D-NMR experiments (1H,13C, COSY, HSQC, ...
Source: Natural Product Research - November 11, 2023 Category: Biochemistry Authors: Assia Khalfallah Zahia Kabouche Ahmed Kabouche Djemaa Berrehal Naima Boutaghane Laurence Voutquenne-Nazabadioko Source Type: research
Preparation and evaluation of smart food packaging films with anthocyanin Sardasht black grape based on Astragalus gummifer and chitosan nanoparticles
Int J Biol Macromol. 2023 Nov 8;254(Pt 2):127974. doi: 10.1016/j.ijbiomac.2023.127974. Online ahead of print.ABSTRACTA new and green development in the field of food packaging is the use of colorimetric films containing anthocyanins, which not only can respond to food spoilage but also have no environmental risk and help the environment full of unacceptable and polluted substances created by humans. In this research, a completely natural film (GCNG) was made using natural materials including tragacanth gummifer (G), chitosan nanoparticles (C), and an extract containing anthocyanins of a type of wild grape called Sardasht b...
Source: International Journal of Biological Macromolecules - November 10, 2023 Category: Biochemistry Authors: Marzieh Piryaei Shabnam Azimi Source Type: research
Formononetin attenuates high glucose-induced neurotoxicity by negatively regulating oxidative stress and mitochondrial dysfunction in Schwann cells via activation of SIRT3
Food Chem Toxicol. 2023 Nov 7:114156. doi: 10.1016/j.fct.2023.114156. Online ahead of print.ABSTRACTHigh glucose induces Schwann cells death and neurotoxicity. Formononetin was originally found in Astragalus membranaceus and showed anti-tumor and anti-neuroinflammation properties. The aim of this study is to explore the molecular mechanism underlying the neuroprotective effects of formononetin and identify its direct protein target. The effects of formononetin on oxidative stress and mitochondrial dysfunction in Schwann cells induced by high glucose were investigated. High glucose treatment significantly induced oxidative ...
Source: Food and Chemical Toxicology - November 9, 2023 Category: Food Science Authors: Wen Jiang Ting Hu Chen Ye Man Hu Qingqing Yu Lijuan Sun Jichao Liang Yong Chen Source Type: research
