Astragalus polysaccharides promote neural stem cells-derived oligodendrogenesis through attenuating CD8 < sup > + < /sup > T cell infiltration in experimental autoimmune encephalomyelitis
In this study, our data illustrated that APS administration could promote NSCs in the subventricular zone (SVZ) to differentiate into oligodendrocytes. Furthermore, we found that APS significantly improved neuroinflammation and inhibited CD8+T cell infiltration into SVZ of EAE mice. We also found that MOG35-55-specific CD8+T cells suppressed NSCs differentiation into oligodendrocytes by secreting IFN-γ, and APS facilitated the differentiation of NSCs into oligodendrocytes which was related to decreased IFN-γ secretion. In addition, APS treatment did not show a better effect on the NSCs-derived oligodendrogenesis after CD...
Source: International Immunopharmacology - December 3, 2023 Category: Allergy & Immunology Authors: Yan Zhao Jinyun Ma Guiqing Ding Yuanhua Wang Hua Yu Xiaodong Cheng Source Type: research

Astragalus polysaccharides promote neural stem cells-derived oligodendrogenesis through attenuating CD8 < sup > + < /sup > T cell infiltration in experimental autoimmune encephalomyelitis
In this study, our data illustrated that APS administration could promote NSCs in the subventricular zone (SVZ) to differentiate into oligodendrocytes. Furthermore, we found that APS significantly improved neuroinflammation and inhibited CD8+T cell infiltration into SVZ of EAE mice. We also found that MOG35-55-specific CD8+T cells suppressed NSCs differentiation into oligodendrocytes by secreting IFN-γ, and APS facilitated the differentiation of NSCs into oligodendrocytes which was related to decreased IFN-γ secretion. In addition, APS treatment did not show a better effect on the NSCs-derived oligodendrogenesis after CD...
Source: International Immunopharmacology - December 3, 2023 Category: Allergy & Immunology Authors: Yan Zhao Jinyun Ma Guiqing Ding Yuanhua Wang Hua Yu Xiaodong Cheng Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research

< em > Astragalus membranaceus < /em > and < em > Cinnamomum cassia < /em > Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/ β-Catenin Signaling Pathway
In conclusion, the YH complex consisting of A. membranaceus and C. cassia induced hair follicle differentiation and preserved the growing-anagen phase by increasing growth factors and the Wnt/β-catenin signaling pathway, leading to the restoration of hair loss. The YH complex can be a remedy for hair loss diseases, such as alopecia areata, androgenetic alopecia, telogen effluvium, and chemotherapy-induced alopecia.PMID:37998718 | PMC:PMC10670826 | DOI:10.3390/cimb45110541 (Source: Current Issues in Molecular Biology)
Source: Current Issues in Molecular Biology - November 24, 2023 Category: Molecular Biology Authors: Mi Hye Kim Seong Chul Jin Hee Kyung Baek Woong Mo Yang Source Type: research