Astragalus polysaccharides ameliorates experimental colitis by regulating memory B cells metabolism
Chem Biol Interact. 2024 Mar 22:110969. doi: 10.1016/j.cbi.2024.110969. Online ahead of print.ABSTRACTIt is well-established that the reduced Memory B cells (MBCs) play an important role in the pathogenesis of ulcerative colitis (UC), rendering them a potential therapeutic target for UC intervention. Astragalus polysaccharide (APS), a primary active constituent derived from the classic traditional Chinese medicine Astragalus membranaceus (AM), has been used for centuries in the treatment of UC in both human and animal subjects due to its renowned immunomodulatory properties. However, it is unknown whether APS can regulate ...
Source: Chemico-Biological Interactions - March 24, 2024 Category: Molecular Biology Authors: Yifei Deng Lizhao Song Jiaqi Huang Wen Zhou Yali Liu Xiuyun Lu Haimei Zhao Duanyong Liu Source Type: research
