COVID herd immunity: At hand or forever elusive?
By MICHEL ACCAD, MD With cases of COVID-19 either disappeared or rapidly diminishing from places like Wuhan, Italy, New York, and Sweden, many voices are speculating that herd immunity may have been reached in those areas and that it may be at hand in the remaining parts of the world that are still struggling with the pandemic. Lockdowns should end—or may not have been needed to begin with, they conclude. Adding plausibility to their speculation is the discovery of biological evidence suggesting that prior exposure to other coronaviruses may confer some degree of immunity against SARS-CoV2, an immunity not apparent on the basis of antibody seroprevalence studies. Opposing those viewpoints are those who dismiss the recent immunological claims and insist that rates of infections are far below those expected to confer immunity on a community. They believe that the main reason for the declining numbers are the behavioral changes that have occurred either under force of government edict or, in the case of Sweden, more voluntarily. What’s more, they remind us that the Spanish flu pandemic of 1918-1919 occurred in 3 distinct waves. In the summer of 1918 influenza seemed overcome until a second wave hit in the fall. Herd immunity could not possibly have accounted for the end of the first wave. The alarmists may have a point. However, recent history offers a more instructive example. Until early 2015, epidemiologists co...
Publication date: 5 February 2021Source: Journal of Molecular Structure, Volume 1225Author(s): Yuqing Wu, Rui Fausto
Publication date: 5 February 2021Source: Journal of Molecular Structure, Volume 1225Author(s): Abhijit Chhetri, Sailesh Chettri, Pranesh Rai, Dipu Kumar Mishra, Biswajit Sinha, Dhiraj Brahman
Publication date: Available online 24 September 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Ritika Kabra, Shailza Singh
Publication date: November 2020Source: Fish &Shellfish Immunology, Volume 106Author(s): Max J. Beckmann, Marcia Saraiva, Debbie McLaggan, Tom G. Pottinger, Pieter van West
Publication date: Available online 24 September 2020Source: Chinese Journal of Chemical EngineeringAuthor(s): Yang Yu, Guiying Li, Wanqing Han, Linhua Zhu, Tian Si, Hong Wang, Yanlin Sun, Yanping He
Analyst, 2020, Advance Article DOI: 10.1039/D0AN01609H, PaperSurasak Kasetsirikul, Muhammad Umer, Narshone Soda, Kamalalayam Rajan Sreejith, Muhammad J. A. Shiddiky, Nam-Trung Nguyen This work reports the development of a rapid, simple and inexpensive colorimetric paper-based assay for the detection of the severe acute respiratory symptom coronavirus 2 (SARS-CoV-2) humanized antibody. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Analysis suggests too little attention is paid to gender disparities in medical trialsCoronavirus – latest updatesSee all our coronavirus coverageHistorically, medical research has often taken a one-size-fits-all approach, lumping women and men together despite growing evidence that the sexes differ in how they catch and fight disease.A stark example was the heart drug digoxin, which was widely marketed in the late 1990s on the basis of a trial that showed it to beeffective and safe. But over time a higher incidence of side-effects in women emerged. When the same dataset wasanalysed on the basis of sex, it showed dig...
WHO warns death tollcould be higher than 2 million without concerted action;Madrid braces for lockdown as Spain reaches 716,481 total infections;surge in cases in AthensFigures prompt French and Dutch warnings, and row in SpainUS approaches 7m cases as officials warn surge could comeWhat lessons can Europe learn from Sweden ’s experience?Why dogs might be a Covid tester ’s best friend7.50pmBSTOfficials have stopped a Covid-19 testing study in theUSafter multiple reports that state and federal public health workers were threatened and face racial slurs.The U.S. Centers for Disease Control and Prevention pulled f...
Integumen, a British company that developed a system to detect the COVID-19 virus in waste water, said the same technology could be deployed in a personalized breath test.Reuters Health Information
Authors: Mishra VN, Kumari N, Pathak A, Chaturvedi RK, Gupta AK, Chaurasia RN Abstract An outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in Wuhan City, China, in December 2019. Since then, the outbreak has grown into a global pandemic, and neither a vaccine nor a treatment for the disease, termed coronavirus disease 2019 (COVID-19), is currently available. The slow translational progress in the field of research suggests that a large number of studies are urgently required. In this context, this review explores the impact of bacteriophages on SARS-CoV-2, especially conce...
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