Five healthy habits net more healthy years
Are healthy habits worth cultivating? A recent study suggests healthy habits may help people tack on years of life and sidestep serious illnesses, such as diabetes and cancer. After all, if you’re going to gain an extra decade of life on this earth, you want to enjoy it! What did this research focus on? Researchers from the Harvard T.H. Chan School of Public Health looked at data from more than 73,000 women enrolled in the Nurses’ Health Study (NHS) who were followed for 34 years, and more than 38,000 men enrolled in the Health Professionals Follow-up Study (HPFS) who were followed for 28 years. In a previous study using the same data, these researchers had found that five low-risk lifestyle habits are critical for a longer life expectancy. The more of these habits people had, the longer they lived. The habits were: a healthy diet, which was calculated and rated based on reports of regularly eating healthy foods like vegetables, fruits, nuts, whole grains, healthy fats, and omega-3 fatty acids, and avoiding less healthy or unhealthy foods like red and processed meats, sugar-sweetened beverages, trans fat, and excess sodium a healthy physical activity level, measured as at least 30 minutes a day of moderate to vigorous activity, like brisk walking a healthy body weight, defined as a normal body mass index (BMI), which is between 18.5 and 24.9 never smoking, because there is no healthy amount of smoking low-risk alcohol intake, measured as between 5 and 15 grams pe...
Athletic performance and physique have been closely associated with diet and nutrition for ages. One such diet is the ketogenic diet, increasingly favored by many athletes.ACC.org
Publication date: Available online 30 March 2020Source: Materials LettersAuthor(s): Lignesh Durai, Arthi Gopalakrishnan, Sushmee Badhulika
Publication date: Available online 30 March 2020Source: NeuronAuthor(s): Kengo Nomura, Miho Nakanishi, Fumiyoshi Ishidate, Kazumi Iwata, Akiyuki Taruno
Publication date: Available online 30 March 2020Source: Food HydrocolloidsAuthor(s): Farhad Alavi, Zhigang Tian, Lingyun Chen, Zahra Emam-Djomeh
Contributors : David Ulmert ; Robert J KleinSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensWe used RNA sequencing to analyze the genomic signatures of prostate cancer that progressed after targeted alpha therapy.
Contributors : Lewis Liu ; Sonya A MacParland ; Jeff C Liu ; Gary D Bader ; Ian D McGilvraySeries Type : Expression profiling by high throughput sequencingOrganism : Marmota monaxWe characterized the identity of hepatic macrophages from the uninvolved liver of a WHV-positive (area with no visible tumor) tumor bearing woodchuck that take up NPs using RNA-sequencing (RNA-seq). Data from WHV-infected animal from experiment 3.
In this study, we identified reliable miRNA clusters that can be used to subclassify HNSCC tumors as well as other squamous tumors of other anatomic locations. An institutional discovery cohort was generated using miRNA expression data from microarrays, and this was validated using publicly available next-generation microRNA sequencing data from TCGA. Further analysis of these subtypes revealed distinct biological and clinical features of HNSCC tumors based on the miRNA expression profiles, which provides new insights into the pathogenesis and treatment of HNSCC.
Contributors : Samir Devalaraja ; Tsun K To ; Ian W Folkert ; Ramakrishnan Natesan ; Zahidul Alam ; Minghong Li ; Yuma Tada ; Konstantin Budagyan ; Mai Dang ; Li Zhai ; Graham P Lobel ; Gabrielle E Ciotti ; T K Eisinger-Mathason ; Irfan A Asangani ; Kristy Weber ; M C Simon ; Malay HaldarSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe immunosuppressive tumor microenvironment (TME) is a major barrier to immunotherapy. Within solid tumors, why monocytes preferentially differentiate into immunosuppressive tumor associated macrophages (TAMs) but not immunostimulatory dendritic cells (...
Contributor : Johannes TextorSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensCancer vaccines utilizing naturally circulating dendritic cell (DC) subsets, such as plasmacutoid DCs (pDCs) and type 2 convential DCs (cDC2s), have demonstrated their potential as a therapy. For melanoma in recent clinical trials. These DC vaccines aim to. human. DC subsets on the. T cell transcriptional program, which. forms the. molecular. basis. of an. antitumor. T cell response, is. poorly understood. In. this study, we investigated the eraly gene expressionsignature of CD8+ T. cells following. stimulati...
CONCLUSION: network analyses confirm GDF15 as upregulated with calorie restriction-induced weight loss, concomitantly to macrophages markers.
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