Th2-TRMs Maintain Life-Long Allergic Memory in Experimental Asthma in Mice

This study was carried out in strict accordance with the guidelines for the care and use of laboratory animals of the Austrian Ministry of Science. The protocol was approved by the Committee on the Ethics of the Austrian Ministry of Science (Number: GZ: 66.009/0330-II/3b/2013). All painful procedures were performed under anesthesia, and all efforts were made to minimize suffering. Author Contributions BB designed and performed experiments, analyzed the samples and contributed to the manuscript preparation. SK designed and performed experiments, analyzed the samples and contributed to the manuscript preparation. LA performed experiments and contributed to the manuscript preparation. GM contributed to immunofluorescent staining of the lungs. ME supervised experiments and contributed to the manuscript preparation. All authors read and approved final version of the manuscript. Funding The work was funded by the Public Private Partnership for Asthma Imaging and Genomics (P3AGI) FP7 Project, under grant No #230739 and the Hochschuljubilaeumsstiftung der Stadt Wien No. H-314145/2017. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments The authors would like to thank Wolfgang Weninger, Frank Brombacher, Shu-Hua Liu, and Sabelo Hadebe for the critical reading of the manuscript and Pavol Mikolka and Georg...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research