More Maternal Vascular Malperfusion and Chorioamnionitis in Placentas After Expectant Management vs. Immediate Delivery in Fetal Growth Restriction at (Near) Term: A Further Analysis of the DIGITAT Trial

More Maternal Vascular Malperfusion and Chorioamnionitis in Placentas After Expectant Management vs. Immediate Delivery in Fetal Growth Restriction at (Near) Term: A Further Analysis of the DIGITAT Trial Marjon E. Feenstra1†, Mirthe H. Schoots2†, Torsten Plösch1, Jelmer R. Prins1, Sicco A. Scherjon1, Albertus Timmer2, Harry van Goor2 and Sanne J. Gordijn1* 1Department of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands 2Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands Objective: Management of late fetal growth restriction (FGR) is limited to adequate fetal monitoring and optimal timing of delivery. The Disproportionate Intrauterine Growth Intervention Trial At Term (DIGITAT) trial compared induction of labor with expectant management in pregnancies at (near) term complicated by suspected FGR. Findings of the DIGITAT trial were that expectant monitoring prolonged pregnancy for 10 days and increased birth weight with only 130 grams. This resulted in more infants born below the 2.3rd percentile compared to induction of labor, respectively, 12.5% in induction of labor and 30.6% in expectant monitoring group. The main placental lesions associated with FGR are maternal vascular malperfusion, fetal vascular malperfusion, and villitis of unknown etiology. We investigated whether placentas of pregnancies complicate...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research

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Publication date: September–October 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 14, Issue 5Author(s): Dukhabandhu Naik, Felix K. Jebasingh, Nihal Thomas, Sreekanth Raveendran, Samuel C. Raj Pallapati, John Jude Prakash, Mahasampath Gowri, Binu Prathap Thomas
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: September–October 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 14, Issue 5Author(s): C. Padmapriya, S. Pushkarapriya, N. Shanmugapriya, K.P. Sushmitha, S. Karthik, M.G. Rajanandh
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: September–October 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &Reviews, Volume 14, Issue 5Author(s): Anju M., Saleena Ummer V, Arun G. Maiya, Manjunath Hande, Binu V.S.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 7 July 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Nariman Essmat, Eman Soliman, Mona F. Mahmoud, Amr A.A. Mahmoud
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
CONCLUSION: Breast ultrasound shows a high sensitivity to detect breast cancer during pregnancy. BCP is diagnosed at a higher stage than in nonpregnant women. In our series, patients with BCP had poorer outcomes than the not pregnant group. These results were not observed when adjusting for stage. PMID: 32623975 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
Authors: Ruiz-Manzanera JJ, Febrero B, Rodríguez JM PMID: 32624259 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
TETANUS VACCINE DURING PREGNANCY: DATA OF A TERTIARY HOSPITAL IN TURKEY. Turk J Med Sci. 2020 Jul 06;: Authors: DaĞdevİren G, ÖrgÜl G, YÜcel A, Şahİn D Abstract BACKGROUND/AIM: To evaluate the prevalence of tetanus vaccination in pregnant women, and to determine the factors affecting the vaccination and barriers to the vaccination. MATERIALS AND METHODS: We conducted an observational-descriptive study with 494 patients who gave birth in Etlik Zubeyde Hanım Women's Health Training and Research Hospital, Ankara, Turkey. Participants were divided into two groups; vaccinated and not...
Source: Turkish Journal of Medical Sciences - Category: General Medicine Tags: Turk J Med Sci Source Type: research
Intermittent fasting regimens for patients with type 2 diabetes should be limited to individuals for whom the risk of hypoglycemia is closely monitored and medications are carefully adjusted.Medscape Medical News
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
CONCLUSION: The average cure rate with anthelminthic treatment is over 95%. Unfortunately, most treated patients in endemic areas become re-infected within months. Health education, personal hygiene, improved sanitary conditions, proper disposal of human excreta, and discontinuing the use of human fecal matter as a fertilizer are effective long-term preventive measures. Targeting deworming treatment and mass anthelminthic treatment should be considered in regions where A. lumbricoides is prevalent. PMID: 32628606 [PubMed - as supplied by publisher]
Source: Recent Patents on Inflammation and Allergy Drug Discovery - Category: Allergy & Immunology Tags: Recent Pat Inflamm Allergy Drug Discov Source Type: research
Authors: Ziemlewicz TJ, Hinshaw JL, Lubner MG, Knott EA, Willey BJ, Lee FT, Brace CL Abstract Purpose: The goal of this study was to compare intra-procedural radiofrequency (RF) and microwave ablation appearance on non-contrast CT (NCCT) and ultrasound to the zone of pathologic necrosis.Materials and methods: Twenty-one 5-min ablations were performed in vivo in swine liver with (1) microwave at 140 W, (2) microwave at 70 W, or (3) RF at 200 W (n = 7 each). CT and US images were obtained simultaneously at 1, 3, and 5 min during ablation and 2, 5, and 10 min post-...
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
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