Here ’s the Healthiest Way to Gain Weight

For most Americans with weight issues, the problem is carrying around too much , not too little. While obesity rates have surged in North America since the 1970s, the proportion of underweight people has remained low—less than 5% of the population, according to a study in The Lancet. These bodyweight trends mean that most health experts are focused on helping people lose weight to avoid disease. But there are also some potentially serious health consequences associated with being clinically underweight, which is usually defined as having a body mass index (BMI) of 18.5 or below. “There are many epidemiologic studies that indicate that underweight in adults and older people is associated with higher risk of death or mortality,” says Kay-Tee Khaw, a professor of clinical gerontology at the University of Cambridge in the UK. There are a range of possible explanations why. For some, a low BMI coupled with unexplained weight loss may be an indication of an underlying medical condition such as cancer. Also, bone and muscle (not just fat) contribute to body weight and BMI. Being underweight may be an indicator of loss of bone and muscle mass—and therefore frailty—particularly in older adults, Khaw says. Frailty can increase a person’s risks for weakness, falls, broken bones and other health problems. Another explanation: People who are naturally very slim may feel free to eat more junk food, smoke, skip exercise or engage in other unhealthy behav...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Diet/Nutrition Source Type: news

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Date: Wednesday, 07 17, 2019; Speaker: Mary Kearney, PhD, Head, Translational Research Unite, HIV Dynamics and Replication Program, Center, National Cancer Institute; https://bit.ly/2RyT8Kw
Source: NIH Calendar of Events - Category: American Health Source Type: events
ConclusionThus our results showed that higher IL-37 was associated with increased insulin sensitive in elderly type 2 DM patients through suppressing the gut microbiota dysbiosis.
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
In this study, we constructed a dual function nanosystem, copper sulfide nanoplatform loaded with the chemotherapeutic drug docetaxel wrapped by a conjugated polymer-peptide for targeted chemo-phototherapy. The nanoconstruct has been successfully designed with a size of 186.1 ± 5.2 nm, a polydispersity index of 0.18 ± 0.01, and zeta potential of −16.4 ± 0.1 mV. The enhanced uptake and near-infrared-responsive behavior of the nanosystem resulted in efficient drug release, photothermal ablation, effective cytotoxic activity, and potentiated reactive oxygen sp...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
Publication date: Available online 22 June 2019Source: Materials TodayAuthor(s): Sheng Tong, Haibao Zhu, Gang BaoAbstractMagnetic iron oxide nanoparticles (MIONs) are among the first generation of nanomaterials that have advanced to clinic use. A broad range of biomedical techniques have been developed by combining the versatile nanomagnetism of MIONs with various forms of applied magnetic fields. MIONs can generate imaging contrast and provide mechanical/thermal energy in vivo in response to an external magnetic field, a special feature that distinguishes MIONs from other nanomaterials. These properties offer unique oppor...
Source: Materials Today - Category: Materials Science Source Type: research
In this study, the nasopharyngeal carcinoma cell line was cultured in a superparamagnetic iron oxide nanoparticle aqueous solution with a concentration of 1 μg/mL by using magnetic labeling technology. The cells took up superparamagnetic nanoparticles through the endocytosis process, which caused the cells to become magnetic and manipulable by a magnetic field gradient. Each cell contained 5.266 × 106 superparamagnetic nanoparticles, as determined using the magnetophoresis method. A specific domain configuration and its related distribution of magnetic poles in a patterned thin film were obtained after apply...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
This study explores the separation of oil compounds such as triglycerides and free fatty acids as well as solvent recovery using a series of Evonik commercial membranes. Under a static testing condition, the permeance of Duramem 500 reduces severely from 1.02 to 0.06 LMH/bar with an increase in oil concentration while its rejection to glyceryl trilinoleate decreases slightly from 86 to 84.8% when the feed concentration increases from 5 to 50 wt%. The severe permeance decline arises from the high viscosity of the permeate and oil layers accumulated on the membrane surface. In contrast, the membrane is able to separate gly...
Source: Journal of Membrane Science - Category: Materials Science Source Type: research
Publication date: Available online 22 June 2019Source: Neuroscience LettersAuthor(s): Q. Leyrolle, S. Laye, A. NadjarAbstractMicroglia are key players in brain function by maintaining brain homeostasis across lifetime. They participate to brain development and maturation through their ability to release neurotrophic factors, to remove immature synapses or unnecessary neural progenitors. They modulate neuronal activity in healthy adult brains and they also orchestrate the neuroinflammatory response in various pathophysiological contexts such as aging and neurodegenerative diseases. One of the main features of microglia is t...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Higher intake of gluten early in life is associated with an increased risk of celiac disease (CD) and CD autoimmunity, according to new findings.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Gastroenterology News Source Type: news
The headlines say that  Milan and Cortina d’Ampezzo, Italy, have been awarded the 2026 Winter Olympics. Ten years from now Italians may look back on today as a disaster. More and more cities are realizing that Olympic games are glamorous but not economically sound. I  made that point four years ago when Boston withdrew its bid to host the 2024 Summer Olympics:The [Boston] critics knew something that the Olympic enthusiasts tried to forget: Megaprojects like the Olympics are enormously expensive, always over budget, and disruptive. They leave cities with unused stadiums and other waste.E.M. Sw...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
We examined the U.S. thoracic surgery workforce using the 2010 and 2014 Area Health Resource Files. We calculated the density of thoracic surgeons per 100,000 persons for each year at the state and county level. We performed descriptive statistics and developed maps highlighting changes over time and geographic regions.ResultsDespite an overall increase in thoracic surgeons from 2010 to 2014, we observed declining density nationwide (1.5% change) and in sparsely populated states. The difference in thoracic surgeon density widened slightly between 2010 from 0.80 per 100,000 compared to 0.84 per 100,000 in 2014 in all rural ...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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