Log in to search using one of your social media accounts:

 

Expanding waistline linked to an increased risk of cancer

Conclusion This study provides more evidence of the link between excess body fat and 10 cancers. Though the percentage increases sound large, it's important to put these results into context. For example, the baseline risk of postmenopausal cancer was 2.2% – it occurred in 555 of the 24,751 women in the study. For women who hadn't used hormone therapy, this would increase to a risk of 2.7% if they had a BMI of 30 compared with 26, or a waist circumference of 95cm compared with 84cm. This accounts for only an extra 5 cases in every 1,000 women. This large study involved older adults from European countries, so the results should be applicable to people in the UK. Its strengths also include the fact researchers analysed data for each individual rather than relying on published results from each study, which could have used different definitions and cut-offs. As ever, though, there are some limitations to be aware of: There were differences between the cohorts, such as length of follow-up and age at entry into the study. Other medical conditions and medication weren't included in the analysis. Diet wasn't taken into account. Though the researchers looked at smoking, physical activity, and alcohol, they weren't able to analyse the results for different amounts of each. The obesity-related cancers were combined in the analysis because of small numbers, so we don't know if there was variation in risk between them. The length of follow-up may not have been...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Obesity Source Type: news

Related Links:

This article is intended to facilitate differential diagnosis by a systematic description of relevant pathologies, notably with occupational etiology. Clinical findings of relevant diseases, i. e. of tuberculosis, chronic beryllium disease, sarcoidosis, lung cancer, malignant lymphoma, Epstein-Barr virus infection, and histoplasmosis are compared.Case history, imaging and laboratory tests have important diagnostic impact. But also invasive methods can be necessary in order to exclude and prove malignancy, infection or autoimmune disease. PMID: 29046010 [PubMed - as supplied by publisher]
Source: Pneumologie - Category: Respiratory Medicine Tags: Pneumologie Source Type: research
In this study, we developed a monoclonal antibody against the extracellular domain (ECD) of HER2 biomarker of breast cancer. For this purpose, the ECD-HER2 gene was amplified and cloned into an expression vector. Gene was generated in Escherichia coli BL21 (DE3) strain for expression of recombinant protein. The expressed protein was separated by SDS-PAGE and detected by anti-his monoclonal antibody in immunoblotting. Hybridoma cells were obtained by fusing myeloma cells with mouse spleen cells injected with recombinant ECD-HER2 and screened by ELISA for the production of monoclonal antibody. The results indicate that out o...
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
Authors: Babic I, Nurmemmedov E, Yenugonda VM, Juarez T, Nomura N, Pingle SC, Glassy MC, Kesari S Abstract Immunotherapy is now at the forefront of cancer therapeutic development. Gliomas are a particularly aggressive form of brain cancer for which immunotherapy may hold promise. Pritumumab (also known in the literature as CLNH11, CLN-IgG, and ACA-11) was the first monoclonal antibody tested in cancer patients. Pritumumab is a natural human monoclonal antibody developed from a B lymphocyte isolated from a regional draining lymph node of a patient with cervical carcinoma. The antibody binds ecto-domain vimentin on t...
Source: Human Antibodies - Category: Biochemistry Tags: Hum Antibodies Source Type: research
We report on a 52-year-old woman with cardiomyopathy following chemotherapy and radiation therapy. The patient did not respond well to b-blockers and angiotensin-converting enzyme inhibitors. After the addition of exogenous phosphocreatine, the patient's cardiac condition improved significantly. PMID: 29038417 [PubMed - in process]
Source: Reviews in Cardiovascular Medicine - Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research
According to a study published inOncotarget, palbociclib, normally used in the treatment of breast cancer, can be used to treat papillary thyroid carcinomas that are resistant to vemurafenib.Medical Xpress
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
A new study in theBritish Journal of Cancerssuggests reports that the therapeutic strategy, commonly used to treat prostate cancer, may result in an increase of cardiovascular disease.Medical News Today
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Intermittent fasting helps prevent diabetes, obesity and reduces cardiovascular risk, by stimulating metabolism to generate heat, says study inCell Metabolism.Science Daily
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Orally administered semaglutide successfully reduces blood glucose in type 2 diabetes patients, and also promotes weight loss, according to research published inJAMA.Express
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Grade: Specialty RegistrarContract: Fixed term - 6 monthsHours: Full time - 40h/weekJob Ref.: 309-MB293-JH-ASalary: £30,605 -£48,123 pa plus London weightingClosing: 13/11/2017 23:59An opportunity has arisen for an enthusiastic and motivated registrar level or senior CMT level doctor with experience in diabetes& endocrinology to join our team. You should have with excellent communication, team and clinical skills to join the Diabetes& Endocrinology Team. This post is a Specialist Registrar level and you will work closely with the Consultants, Specialist Registrars, Nurse Co...
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
Grade: Specialty RegistrarContract: Fixed term - 12 monthsHours: Part time - 20h/weekJob Ref.: 309-MB299-JH-ASalary: £30,605 -£48,123 pa plus London weightingClosing: 13/11/2017 23:59Applications are invited for a one-year clinical research fellow in pituitary endocrinology post, suitable for a registrar level or senior CMT level doctor. This would suit someone planning to commence training in Diabetes& Endocrinology, taking time out of programme or a post CCT D&E applicant wishing to gain more pituitary and research experience. You should have excellent communication, team...
Source: Society for Endocrinology - Category: Endocrinology Source Type: news
More News: Alcoholism | Breast Cancer | Cancer | Cancer & Oncology | Cardiology | Cardiovascular | Colorectal Cancer | Diabetes | Eating Disorders & Weight Management | Education | Endocrinology | Endometrial Cancer | Esophagus Cancer | Gallbladder Cancer | Gastric (Stomach) Cancer | Health | Heart | Hormonal Therapy | Hormone Replacement Therapy | Hormones | Liver | Medical Ethics | Nutrition | Obesity | Ovarian Cancer | Ovaries | Pancreas | Pancreatic Cancer | Prostate Cancer | Science | Smokers | Study | Universities & Medical Training | Urology & Nephrology | Women