Expanding waistline linked to an increased risk of cancer
Conclusion This study provides more evidence of the link between excess body fat and 10 cancers. Though the percentage increases sound large, it's important to put these results into context. For example, the baseline risk of postmenopausal cancer was 2.2% – it occurred in 555 of the 24,751 women in the study. For women who hadn't used hormone therapy, this would increase to a risk of 2.7% if they had a BMI of 30 compared with 26, or a waist circumference of 95cm compared with 84cm. This accounts for only an extra 5 cases in every 1,000 women. This large study involved older adults from European countries, so the results should be applicable to people in the UK. Its strengths also include the fact researchers analysed data for each individual rather than relying on published results from each study, which could have used different definitions and cut-offs. As ever, though, there are some limitations to be aware of: There were differences between the cohorts, such as length of follow-up and age at entry into the study. Other medical conditions and medication weren't included in the analysis. Diet wasn't taken into account. Though the researchers looked at smoking, physical activity, and alcohol, they weren't able to analyse the results for different amounts of each. The obesity-related cancers were combined in the analysis because of small numbers, so we don't know if there was variation in risk between them. The length of follow-up may not have been...
ConclusionsThe expression of N-cadherin in metastatic lymph nodes is useful for predicting the prognosis of patients with gastric cancer. The Snail switch —namely, the positive-to-negative conversion of the Snail status—between primary tumors and lymph node metastasis may be important for confirming EMT and mesenchymal–epithelial transition.
ConclusionsDNA CY1 detected by Q-MSP forCDO1 gene promoter DNA methylation has a great potential to detect minimal residual disease of the peritoneum in GC clinics as a novel DNA marker.
OESOPHAGEAL cancer - or cancer of the gullet - could be treated with a existing drug in a new way, experts have found.
Experts warn the study by the University of Bristol underlines how rising obesity rates among teenagers could have devastating implications for the digestive health of future generations.
NEW YORK (Reuters) - A massive California verdict in a lawsuit alleging Johnson&Johnson's talc-based products cause cancer has opened a new front in the litigation, upending the company's hopes that the cases were only gaining traction in Missouri, legal experts said.
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We report a series of eight patients with adverse reactions to VCR over the course of 11 months at a single institution, four of which progressed to anaphylaxis and one of which resulted in cardiac arrest. Mass spectrometry analysis of medication lots was performed to test for possible contaminant(s). Our findings highlight the risk of anaphylaxis during therapy with VCR.
CONCLUSIONSEvidence of low distress during the time of cancer screening suggests that distress might not be a widespread barrier to screening among adults who undergo screening. However, more studies are needed using validated measures of distress to further understand the extent to which screening may elicit psychological distress and impede adherence to national screening recommendations. Cancer 2017. © 2017 American Cancer Society.
Date: Thursday, 11 09, 2017; Speaker: Karla Kaun, Professor, Brown University; Building: 35; 2G600 (2nd Floor SKYBOX)
(Reuters Health) - People who decide to tackle their cancer using only unconventional methods are likely to die sooner than patients who opt for conventional treatments, according to a new study.
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