Stroma Insights: Potential Mechanism for Arsenic-Induced Prostate Cancer
Julia R. Barrett, MS, ELS, a Madison, WI–based science writer and editor, is a member of the National Association of Science Writers and the Board of Editors in the Life Sciences.
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Citation: Barrett JR. 2016. Stroma insights: potential mechanism for arsenic-induced prostate cancer. Environ Health Perspect 124:A130; http://dx.doi.org/10.1289/ehp.124-A130
Published: 1 July 2016
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Inorganic Arsenic–Related Changes in the Stromal Tumor Microenvironment in a Prostate Cancer Cell–Conditioned Media Model
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There is epidemiological evidence that exposure to inorganic arsenic may cause prostate cancer, but the molecular mechanisms to explain the potential relationship remain unclear.1,2 A new study in EHP looks beyond epithelial prostate cells—the cells most often studied in prostate cancer—to focus on stromal cells, a cell type that normally provides a supportive function. The findings suggest that inorganic arsenic primes these stromal cells to enhance the progression of cancer.1
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Source: EHP Research - Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection July 2016 Source Type: research
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