Web resources bring new insight into COVID-19
Researchers around the world are a step closer to a better understanding of the intricacies of COVID-19 thanks to two new web resources developed by investigators at Baylor College of Medicine and the University of California San Diego. The resources are freely available through the Signaling Pathways Project (Baylor) and the Network Data Exchange (UCSD). (Source: World Pharma News)
Source: World Pharma News - September 22, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

Web resources bring new insight into COVID-19
(Baylor College of Medicine) Two new web resources put at researchers' fingertips information about cellular genes whose expression is affected by coronavirus infection and place these data points in the context of the complex network of host molecular signaling pathways. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - September 22, 2020 Category: Infectious Diseases Source Type: news

Human norovirus strains differ in sensitivity to the body's first line of defense
(Baylor College of Medicine) Human norovirus strains differ in sensitivity to interferon, one of the body's first line of defense. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 10, 2020 Category: International Medicine & Public Health Source Type: news

US-based BCM ties up with India's BE for COVID-19 vaccine production
In the race to find a cure for the coronavirus infection, Texas-based Baylor College of Medicine (BCM) has entered into a licensing agreement with Indian pharmaceutical company Biological E Limited (BE) for the development of a safe, effective and affordable vaccine. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 28, 2020 Category: Pharmaceuticals Source Type: news

For $5 and in 15 Minutes You Can Learn If You Have COVID-19
On Aug. 26, the U.S. Food and Drug Administration (FDA) gave an emergency use authorization (EUA) for a rapid COVID-19 test that can produce results in just 15 minutes, which could not only increase the number of people tested in the U.S., but also identify those who are positive sooner, so they can self-isolate and limit spread of the disease. The testing device, made by Abbott Laboratories and called BinaxNOW Ag Card, is about the size of a credit card and can be easily used anywhere people need to be tested. It analyzes samples from a nasal swab and comes with an app that people can download to receive their results&mda...
Source: TIME: Health - August 27, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Novel PROTAC enhances its intracellular accumulation and protein knockdown
(Baylor College of Medicine) Researchers at Baylor College of Medicine developed an improved type of PROTAC that has enhanced intracellular accumulation and functions, not only as a degrader, but also as an inhibitor of the target protein. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - August 26, 2020 Category: Cancer & Oncology Source Type: news

To be or not to be in the ER, that is the question
(Baylor College of Medicine) Researchers discovered a new way cells can dispose of misfolded proteins that may help better understand human NGLY1 deficiency. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 25, 2020 Category: International Medicine & Public Health Source Type: news

Fighting cancer with rejection-resistant, 'off-the-shelf' therapeutic T cells
(Baylor College of Medicine) Baylor College of Medicine researchers develop improved cancer-fighting CAR T cells. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 20, 2020 Category: International Medicine & Public Health Source Type: news

Heart attack damage reduced by shielded stem cells
(Rice University) Bioengineers and surgeons from Rice University and Baylor College of Medicine have shown in rodents that a four-week shielded stem cell treatment can reduce damage caused by a heart attack. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 18, 2020 Category: International Medicine & Public Health Source Type: news

Baylor College of Medicine and Biological E sign licensing pact to develop Covid-19 vaccine
BE in a statement on Thursday said it will leverage its experience to develop and commercialise the vaccine candidate, which currently is produced using a proven yeast-based expression technology. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - August 13, 2020 Category: Pharmaceuticals Source Type: news

PolyA-miner assesses the effect of alternative polyadenylation on gene expression
(Baylor College of Medicine) Meet PolyA-miner, a new computational tool that enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - July 23, 2020 Category: Biology Source Type: news

More Mesothelioma Cancer Centers Using Tumor Treating Fields
Tumor Treating Fields is one of the newest treatments on the market for pleural mesothelioma cancer patients with metastatic disease. The device is also available to patients with locally advanced cancer who are not candidates for mesothelioma surgery. Clinical trials of the treatment, previously known as NovoTTF-100L, extended the survival of mesothelioma patients by more than six months compared to those receiving only chemotherapy. The device is now called Optune Lua and has been available outside of clinical trials for over a year. More physicians and treatment centers are becoming certified to prescribe the treatmen...
Source: Asbestos and Mesothelioma News - July 21, 2020 Category: Environmental Health Authors: Fran Mannino Source Type: news

Combating drug resistance in age-related macular degeneration
(Baylor College of Medicine) An international team of researchers led by Baylor College of Medicine and Houston Methodist has discovered a strategy that can potentially address a major challenge to the current treatment for age-related macular degeneration, (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 16, 2020 Category: International Medicine & Public Health Source Type: news

Immunotherapy with CAR T cells results in exceptional patient recovery
(Baylor College of Medicine) In a clinical trial, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of the cancer cells. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 15, 2020 Category: Cancer & Oncology Source Type: news

New androgen receptor structure suggests prostate cancer treatment options
(Baylor College of Medicine) Researchers at Baylor College of Medicine reveal for the first time the complete 3-D structure of the active, full-length androgen receptor-coactivator complex as it interacts with DNA. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 14, 2020 Category: Cancer & Oncology Source Type: news

Nano-radiomics unveils treatment effect on tumor microenvironment
(Baylor College of Medicine) Researchers at Baylor College of Medicine and Texas Children's Hospital have developed a novel noninvasive approach called nano-radiomics that analyzes imaging data to assess changes in the tumor microenvironment that are not detected with conventional imaging methods. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - July 10, 2020 Category: Cancer & Oncology Source Type: news

No NELL2, no sperm motility; novel protein is essential for male fertility
(Baylor College of Medicine) An international team of researchers has identified a chain of events that matures the sperm and triggers their motility. The findings have implications for diagnostic and therapeutic research in male infertility and male contraceptive development. (Source: EurekAlert! - Social and Behavioral Science)
Source: EurekAlert! - Social and Behavioral Science - July 9, 2020 Category: International Medicine & Public Health Source Type: news

Metabolomics meets genomics to improve patient diagnosis
(Baylor College of Medicine) Researchers at Baylor College of Medicine have improved their ability to identify the genetic cause of undiagnosed conditions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - July 7, 2020 Category: International Medicine & Public Health Source Type: news

Solving the CNL6 mystery in Batten disease
(Baylor College of Medicine) Researchers at Baylor College of Medicine uncover how mutations in the human gene CLN6 can lead to a form of Batten disease. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 29, 2020 Category: International Medicine & Public Health Source Type: news

New U.S. Coronavirus Infections Return to Levels at Peak of Outbreak
(HOUSTON) — A coronavirus resurgence is wiping out two months of progress in the U.S. and sending infections to dire new levels across the South and West, with hospital administrators and health experts warning Wednesday that politicians and a tired-of-being-cooped-up public are letting a disaster unfold. The U.S. recorded a one-day total of 34,700 new confirmed COVID-19 cases, the highest level since late April, when the number peaked at 36,400, according to a count kept by Johns Hopkins University. While newly confirmed infections have been declining steadily in early hot spots such as New York and New Jersey, seve...
Source: TIME: Health - June 24, 2020 Category: Consumer Health News Tags: Uncategorized COVID-19 News Desk overnight wire Source Type: news

Slow-growing rotavirus mutant reveals early steps of viral assembly
(Baylor College of Medicine) A serendipitous observation led researchers at Baylor College of Medicine to uncover new insights into the formation of rotavirus viroplasms. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 23, 2020 Category: Biology Source Type: news

Premature epigenomic aging acts like a 'sleeper cell' that is awaken by Western-style diet
(Baylor College of Medicine) Exposure to certain chemicals early in life can reprogram the liver epigenome so that the organism becomes more vulnerable to diet-triggered metabolic problems later in life. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 16, 2020 Category: Biology Source Type: news

A novel mechanism that triggers a cellular immune response
(Baylor College of Medicine) Researchers at Baylor College of Medicine present comprehensive evidence that supports a novel trigger for a cell-mediated response and propose a mechanism for its action. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 11, 2020 Category: Biology Source Type: news

How To Keep Your Skin Healthy While Constantly Wearing A Face Mask
BOSTON (CBS) – If you go out nowadays and you can’t social distance, you’re supposed to wear a mask. But they’re not always comfortable and they can irritate your skin. Across the country, front line health care workers are sharing stories about what happens after wearing a mask for hours at a time. Some get little bumps all around their mouth or they have breakouts on their chins. There’s also the itchiness and redness. Some nurses have coined the term “co-zits” and others are calling it “maskne.” Dermatologist Dr. Rajani Katta at Baylor College of Medicine says when s...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - June 8, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Covid-19 Boston, MA Health Healthcare Status Healthwatch Syndicated Local Coronavirus Dr. Mallika Marshall Source Type: news

New clues on how lipid emulsions prevent liver disease in preterm babies
(Baylor College of Medicine) New evidence links the microbiome and gut bile acids to lipid emulsion prevention of liver disease in preterm babies. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 4, 2020 Category: International Medicine & Public Health Source Type: news

Resistance to immunosurveillance favors cluster cancer metastasis
(Baylor College of Medicine) Researchers at Baylor College of Medicine show that circulating cancer cell clusters are more resistant to NK-cell mediated destruction than single cancer cells, leading to more cluster metastasis. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 1, 2020 Category: Cancer & Oncology Source Type: news

Assessing cancer diagnosis in children with birth defects
In this study, led by Baylor College of Medicine and Texas Children's Hospital, researchers provide a better understanding of cancer risk in children with birth defects. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - May 29, 2020 Category: Cancer & Oncology Source Type: news

Durvalumab Phase III Trial Could Change Mesothelioma Care
An international, much-anticipated phase III clinical trial that could change standard-of-care treatment for patients with malignant pleural mesothelioma will open soon, pending COVID-19 pandemic restrictions. The randomized trial will be studying the effectiveness of the immunotherapy drug durvalumab (Imfinzi) when used in combination with chemotherapy drugs pemetrexed (Alimta) and cisplatin for mesothelioma. Opening dates may vary by center because of the COVID-19 pandemic that has slowed or stalled clinical trials everywhere. Durvalumab produces an antibody that helps a patient’s own immune system kill tumor cell...
Source: Asbestos and Mesothelioma News - May 28, 2020 Category: Environmental Health Authors: Fran Mannino Source Type: news

Researchers find CBD improves arthritis symptoms in dogs
This study shows that in dogs diagnosed with arthritis, CBD treatment significantly improved quality of life as documented by both owner and veterinarian assessments. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 28, 2020 Category: International Medicine & Public Health Source Type: news

There Isn ’t a COVID-19 Vaccine Yet. But Some Are Already Skeptical About It
Amid the American flags, “Make America Great Again” hats and “freedom is essential” posters appearing at recent protests against coronavirus lockdowns in Sacramento, Calif., another familiar slogan has materialized: “We do not consent.” It’s long been a popular rallying cry among antivaccine activists, who claim without evidence that vaccines cause autism or other conditions. As the COVID-19 pandemic rages on, those activists have become intertwined with demonstrators who want businesses to reopen despite public health experts’ warnings. Offline, the “anti-vaxxers&rdquo...
Source: TIME: Health - May 18, 2020 Category: Consumer Health News Authors: Tara Law Tags: Uncategorized COVID-19 Source Type: news

Major League Baseball Is Planning a Comeback. Here ’s Why That Won’t Be Easy
Discussions between baseball’s players and owners will continue despite the ongoing pandemic and the uncertainty it brings. “We’re not seeing massive declines across the country,” says Weatherhead. “To make predictions and plan what is going to happen on July 1 is not possible.” The benefits of baseball’s comeback can’t be discounted. Playing ball would offer quarantined fans, many already struggling economically or otherwise, welcome psychic rewards. Even without fans, baseball would offer communities a financial lift: gameday jobs are at stake. Not to mention the symbolic i...
Source: TIME: Health - May 13, 2020 Category: Consumer Health News Authors: Sean Gregory Tags: Uncategorized Baseball COVID-19 Source Type: news

Prevalence of benign gynecologic lesions higher than previously reported
(Baylor College of Medicine) Over the last decade researchers have become concerned about a possible link between a benign gynecologic lesion called endosalpingiosis (ES) and ovarian cancer. However, using a diagnostic method typically reserved for specimens suspicious for cancer, a team of researchers led by a Baylor College of Medicine physician found the prevalence of ES and other gynecological lesions was substantially higher than previously reported, even among women without cancer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 13, 2020 Category: International Medicine & Public Health Source Type: news

The challenges of developing a safe and effective COVID-19 vaccine
The goal of a vaccine is to trigger a response that safely protects against an infection and/or the burden of disease. While this is true for all vaccines, the steps leading to a safe and effective product can be different for each infection. In the case of COVID-19, caused by the virus SARS-CoV-2, researchers at Baylor College of Medicine and Texas Children's Hospital have found that vaccine design can (Source: World Pharma News)
Source: World Pharma News - May 12, 2020 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news

The challenges of developing a safe and effective COVID-19 vaccine
(Baylor College of Medicine) Researchers at Baylor College of Medicine and colleagues identify critical points to pay close attention to when designing and developing COVID-19 vaccines. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - May 12, 2020 Category: Infectious Diseases Source Type: news

Study reveals how spaceflight affects risk of blood clots in female astronauts
(King's College London) A study of female astronauts has assessed the risk of blood clots associated with spaceflight.The study, published in Aerospace Medicine and Human Performance, in collaboration with King's College London, the Centre for Space Medicine Baylor College of Medicine, NASA Johnson Space Centre and the International Space University, examines the potential risk factors for developing a blood clot (venous thromboembolism) in space. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 5, 2020 Category: International Medicine & Public Health Source Type: news

Researchers identify unique glucose-sensing neurons that regulate blood sugar
(Baylor College of Medicine) At Baylor College of Medicine and other institutions, researchers have identified a group of unique glucose-sensing neurons in the brain and how they work together to prevent severe hypoglycemia in mice. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 1, 2020 Category: International Medicine & Public Health Source Type: news

Innovative approach offers option for treating upper tract urothelial cancer
(Baylor College of Medicine) An innovative form of local chemotherapy using a mitomycin-containing reverse thermal gel offers a kidney-sparing treatment option for low-grade upper tract urothelial cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - April 29, 2020 Category: Cancer & Oncology Source Type: news

Tobacco smoking increases lung entry points for COVID-19 virus
(Baylor College of Medicine) Researchers at Baylor College of Medicine, the University of South Carolina and other institutions have identified tobacco smoking as a potential risk factor for infection of the COVID-19 virus. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 29, 2020 Category: Infectious Diseases Source Type: news

Second Sight Gives Clearer Picture of Strategy Going Forward
Second Sight Medical Products provided an update on its strategic options and gave some clarity on a plan going forward. The Sylmar, CA-based company noted its situation was fluid and would explore options that include securing additional funding and exploring business alternatives that may include partnering, acquiring, investing in, or combining with businesses that may or may not be in a related industry. In a press release, the visual prosthesis firm’s acting CEO Matthew Pfeffer noted the company had been able to attract interest from third parties.   “Since taking over a...
Source: MDDI - April 28, 2020 Category: Medical Devices Authors: Omar Ford Tags: Business Implants Source Type: news

A promising new treatment for recurrent pediatric brain cancer
(Baylor College of Medicine) Researchers developed a novel approach that delivers appropriately-targeted chimeric antigen receptor (CAR) T cell therapy directly into the cerebrospinal fluid that surrounds recurrent pediatric brain tumors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 27, 2020 Category: International Medicine & Public Health Source Type: news

Adult astrocytes are key to learning and memory
(Baylor College of Medicine) Researchers at Baylor College of Medicine discovered that astrocytes, the most abundant cells in the brain, play a direct role in the regulation of adult neuronal circuits involved in learning and memory. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 23, 2020 Category: International Medicine & Public Health Source Type: news

Mystery solved, rotavirus VP3 is a unique capping machine
(Baylor College of Medicine) After eluding researchers for more than 30 years, the VP3 protein of rotavirus has finally revealed its unique structure and function to a team led by scientists at Baylor College of Medicine. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 16, 2020 Category: Infectious Diseases Source Type: news

Solving the puzzle of Mitchell disease
(Baylor College of Medicine) Researchers discovered that ACOX1 is involved in two distinct neurodegenerative disorders. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 16, 2020 Category: International Medicine & Public Health Source Type: news

Scents regulate fat storage without affecting eating behavior
(Baylor College of Medicine) Researchers discovered that, in the lab worm C. elegans, certain scents dynamically regulate fat mobilization by interacting with specific olfactory neurons through specific receptors. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 16, 2020 Category: International Medicine & Public Health Source Type: news

Inventors Are Whipping Up Homemade Ventilators to Fend Off a Shortage. Some Doctors Are Wary
A mechanical ventilator can cost a hospital tens of thousands of dollars up front, and even more money each day it’s used to keep oxygen flowing into a sick patient’s lungs. It’s unsurprising, then, that some small U.S. hospitals can count theirs on one hand. There are about 160,000 ventilators in use in hospitals nationwide—about half the number of confirmed COVID-19 cases in the U.S. as of April 6. As the number of coronavirus diagnoses ticks upward, inventors are resorting to increasingly creative solutions to stave off an impending ventilator shortage. But the stakes are high for getting it righ...
Source: TIME: Health - April 6, 2020 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized COVID-19 Source Type: news

Reusable respirators may be a suitable alternative to disposable respirators
(Baylor College of Medicine) Researchers have found that reusable respirators may be a suitable alternative to disposable N95 respirators currently in high demand. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 26, 2020 Category: Infectious Diseases Source Type: news

Analyzing patients shortly after stroke can help link brain regions to speech functions
(Rice University) New research from Rice University and Baylor College of Medicine shows analyzing the brains of stroke victims just days after the stroke allows researchers to link various speech functions to different parts of the brain, an important breakthrough that may lead to better treatment and recovery. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 23, 2020 Category: International Medicine & Public Health Source Type: news

Researchers find brain cell that triggers tremor and how to control it
(Baylor College of Medicine) Researchers have improved our understanding of how tremor -- the most common movement disorder -- happens, opening the possibility of novel therapies for this condition. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 19, 2020 Category: International Medicine & Public Health Source Type: news

Genetic signature may identify mothers at risk for preeclampsia
(Baylor College of Medicine) Researchers at Baylor College of Medicine have identified a genetic signature combining certain maternal and fetal gene variants that are associated with a higher risk of preeclampsia. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 17, 2020 Category: International Medicine & Public Health Source Type: news

Fruit flies advance research on ACOX1-related neurodegenerative disorders
(Baylor College of Medicine) A study led by researchers at Baylor College of Medicine reports that a hyperactive variant of enzyme ACOX1 produces elevated levels of toxic reactive oxygen species (ROS) and causes a previously unidentified late-onset neurodegenerative disorder. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 12, 2020 Category: International Medicine & Public Health Source Type: news