Why I Eat Red Meat
So many of us have omitted or cut down on our consumption of red meat due to negative reports in the press. However, I believe that unprocessed, grass-fed beef has its place in a healthy diet. Besides the fact that nothing is better than a juicy hamburger on the grill in the summer, the high levels of nutrients it provides can make it a healthy choice. Here are some of the stand-out nutrients you might be missing: Iron Iron is an essential nutrient involved in many different metabolic functions. It is especially important in early childhood cognitive development, energy metabolism and the immune system. One of its most critical functions is the role it plays in developing the red blood cells needed to transport oxygen throughout the body. Iron is classified as Heme Iron (found in animal proteins) and Non-Heme Iron (found in plant foods.) Heme iron is the best absorbed form of iron and utilized more efficiently in the body. Heme iron is not influenced by inhibitors like phytates, calcium and polyphenols found in plant foods. Iron levels in red meat are more bioavailable in red meat than alternative food sources. B Vitamins Red meat is a rich source of B vitamins, especially vitamin B12. B12 cannot be made in the body and is best absorbed through animal protein. It is vital to proper functioning of nearly every system in your body. B12 deficiency can play a role in everything from bone health, cardiovascular disease, thyroid disorders, neurological disorders, and infertility....
Conclusion: This paper addresses the clinical implications of performing numerous CT examinations in patients with cancer, providing clinicians with information regarding methods to reduce risk factors in this patient population.Blood Purif 2018;46:56 –69
Conclusions: RDLs are frequently observed in high-risk patients for gastric cancer after eradication. M-NBI demonstrated significantly superior diagnostic efficacy with respect to RDL.Digestion 2018;98:48 –55
Oil Palm Phenolics Inhibit the In Vitro Aggregation of β-Amyloid Peptide into Oligomeric Complexes. Int J Alzheimers Dis. 2018;2018:7608038 Authors: Weinberg RP, Koledova VV, Shin H, Park JH, Tan YA, Sinskey AJ, Sambanthamurthi R, Rha C Abstract Alzheimer's disease is a severe neurodegenerative disease characterized by the aggregation of amyloid-β peptide (Aβ) into toxic oligomers which activate microglia and astrocytes causing acute neuroinflammation. Multiple studies show that the soluble oligomers of Aβ42 are neurotoxic and proinflammatory, whereas the monomers and insoluble fibr...
This study showed that ESE-16 exposure leads to the aggregation of acidic vesicles, identified as lysosomes, not accompanied by an induction of autophagy. Therefore, ESE-16 disrupts normal endocytic vesicle maturation likely through the inhibition of the microtubule function.Pharmacology 2018;102:9 –16
Conclusions: The sustained effort to self-manage chronic pain could be exhausting, and motivation could wane over time following intervention. Providing intermittent support in the form of booster sessions and peer support groups may be important. Person-centered care via shared decision making and guided problem solving is essential to facilitating ongoing self-management. PMID: 29669089 [PubMed - in process]
Preclinical and clinical studies have shown that viral-based immunotherapy has the potential to overcome resistance to immune checkpoint blockade (ICB) and to fill the unmet needs of many cancer patients. Poxviruses, such as modified vaccinia virus Ankara (MVA), have the potential as cancer immunotherapeutic agents. We recently showed that intratumoral (IT) delivery of inactivated modified vaccinia virus Ankara (iMVA) induces antitumor systemic immunity via the STING-mediated cytosolic DNA-sensing pathway and Batf3 –dependent CD103+/CD8+ dendritic cells (DCs).
Skin cancer is one of the most preventable forms of cancer. Roughly, 85% of skin cancer cases could be avoided by reducing UV exposure, especially during adolescence. We conducted a pilot study to evaluate sun safety behaviors in this age group, as well as, the effects of an innovative intervention in changing sun protection attitudes and behaviours. Methods: Participants were recruited from 8 secondary schools in Vancouver, BC. Participants were segregated into the control arm (N=38) or intervention arm (N=138).
Annabelle Y. Guo, PhD1, Indra Neil Sarkar, PhD1,3, Elizabeth S. Chen, PhD1,3,Joanna Walker, MD2, Paul Stey, PhD3, Wen Qing Li, PhD2, Eunyoung Cho, ScD2, Abrar A. Qureshi, MD21The Warren Alpert Medical School; 2Department of Dermatology; 3Center for Biomedical Informatics, Brown University, Providence, RI. Merkel Cell Carcinoma (MCC) is an aggressive malignant skin cancer with a high mortality rate. The effect of ultraviolet (UV) exposure on MCC patients long-term survival is not fully understood.
Background: The high keratinocyte carcinoma (KC) incidence in Western countries puts pressure on healthcare systems and urges to identify areas for improvement. Aim: To describe current KC care based on routinely collected data in primary and secondary care in the Netherlands. Methods: A retrospective cohort study using the Integrated Primary Care Information database and for specialist care the nationwide Netherlands Cancer Registry. In primary care 1736 records of patients with suspicious KC lesions were included (2009-2013).
Frequent use of sun-protection factor (SPF)>15 sunscreen is an important skin cancer prevention strategy, but little is known about users of SPF15 SPF versus
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