Characterization of hypersaline Oklahoma native microalgae cultivated in flowback and produced water: growth profile and contaminant removal
Bioprocess Biosyst Eng. 2024 Apr 8. doi: 10.1007/s00449-024-02992-8. Online ahead of print.ABSTRACTThis work explores the potential of three hypersaline native microalgae strains from Oklahoma, Geitlerinema carotinosum, Pseudanabaena sp., and Picochlorum oklahomensis, for simultaneous treatment of flowback (FW) and produced wastewater (PW) and the production of algal biomass. The quality of wastewater before and after treatment with these microalgae strains was evaluated and a characterization of algal biomass in terms of moisture, volatile matter, fixed carbon, and ash contents was assessed. The experimental results indic...
Source: Bioprocess and Biosystems Engineering - April 8, 2024 Category: Biomedical Engineering Authors: Giovanni Antonio Lutzu Alessandro Concas Nurhan Turgut Dunford Source Type: research
Response of Male Reproductive System Against Ionizing Radiation and Available Radio-protective Agents: Cellular and Molecular Insight
CONCLUSION: Further study is needed to optimize these tactics and fill knowledge gaps. Also, the effective components of herbal, synthetic drugs, etc., should be isolated and tested up to clinical levels, paving the way for successful radioprotection and radiomitigation strategies in the male reproductive system.PMID:38584548 | DOI:10.2174/0118744710285874240326041025 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - April 8, 2024 Category: Radiology Authors: Ronit Parashar Sanwar Mal Yadav Priyadarshi Meena Raj Kumar Kuldeep S Jheeta Priya Saini Dev Dutt Patel Source Type: research
Inhibition of USP7 enhances CD8 < sup > + < /sup > T cell activity in liver cancer by suppressing PRDM1-mediated FGL1 upregulation
In this study we investigated the role of USP7 in modulation of FGL1-mediated liver cancer immune evasion. We showed that knockdown of USP7 or treatment with USP7 inhibitor P5091 suppressed liver cancer growth by promoting CD8+ T cell activity in Hepa1-6 xenograft mice and in HepG2 or Huh7 cells co-cultured with T cells, whereas USP7 overexpression produced the opposite effect. We found that USP7 upregulated FGL1 in HepG2 and Huh7 cells by deubiquitination of transcriptional factor PR domain zinc finger protein 1 (PRDM1), which transcriptionally activated FGL1, and attenuated the CD8+ T cell activity, leading to the liver ...
Source: Acta Pharmacologica Sinica - April 8, 2024 Category: Drugs & Pharmacology Authors: Lin-Lin Sun Li-Na Zhao Jiao Sun Hong-Feng Yuan Yu-Fei Wang Chun-Yu Hou Pan Lv Hui-Hui Zhang Guang Yang Ning-Ning Zhang Xiao-Dong Zhang Wei Lu Source Type: research
Response of Male Reproductive System Against Ionizing Radiation and Available Radio-protective Agents: Cellular and Molecular Insight
CONCLUSION: Further study is needed to optimize these tactics and fill knowledge gaps. Also, the effective components of herbal, synthetic drugs, etc., should be isolated and tested up to clinical levels, paving the way for successful radioprotection and radiomitigation strategies in the male reproductive system.PMID:38584548 | DOI:10.2174/0118744710285874240326041025 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - April 8, 2024 Category: Radiology Authors: Ronit Parashar Sanwar Mal Yadav Priyadarshi Meena Raj Kumar Kuldeep S Jheeta Priya Saini Dev Dutt Patel Source Type: research
Characterization of hypersaline Oklahoma native microalgae cultivated in flowback and produced water: growth profile and contaminant removal
Bioprocess Biosyst Eng. 2024 Apr 8. doi: 10.1007/s00449-024-02992-8. Online ahead of print.ABSTRACTThis work explores the potential of three hypersaline native microalgae strains from Oklahoma, Geitlerinema carotinosum, Pseudanabaena sp., and Picochlorum oklahomensis, for simultaneous treatment of flowback (FW) and produced wastewater (PW) and the production of algal biomass. The quality of wastewater before and after treatment with these microalgae strains was evaluated and a characterization of algal biomass in terms of moisture, volatile matter, fixed carbon, and ash contents was assessed. The experimental results indic...
Source: Bioprocess and Biosystems Engineering - April 8, 2024 Category: Biomedical Engineering Authors: Giovanni Antonio Lutzu Alessandro Concas Nurhan Turgut Dunford Source Type: research
Response of Male Reproductive System Against Ionizing Radiation and Available Radio-protective Agents: Cellular and Molecular Insight
CONCLUSION: Further study is needed to optimize these tactics and fill knowledge gaps. Also, the effective components of herbal, synthetic drugs, etc., should be isolated and tested up to clinical levels, paving the way for successful radioprotection and radiomitigation strategies in the male reproductive system.PMID:38584548 | DOI:10.2174/0118744710285874240326041025 (Source: Current Radiopharmaceuticals)
Source: Current Radiopharmaceuticals - April 8, 2024 Category: Radiology Authors: Ronit Parashar Sanwar Mal Yadav Priyadarshi Meena Raj Kumar Kuldeep S Jheeta Priya Saini Dev Dutt Patel Source Type: research
Additives for Aqueous Zinc ‐Ion Batteries: Recent Progress, Mechanism Analysis, and Future Perspectives
The roles of anode additives may be summed up as follows: modify the electric double layer, create the solid-electrolyte interface, regulate the zinc facet, and modulate the electric field. Rebuilding the solvation sheath and strengthening the hydrogen bond network are the two main ways that the activities of altering the electrolyte environment can be summed up. AbstractAqueous zinc-ion batteries (ZIBs) stand out as a promising next-generation electrochemical energy storage technology, offering notable advantages such as high specific capacity, enhanced safety, and cost-effectiveness. However, the application of aqueous e...
Source: Small - April 8, 2024 Category: Nanotechnology Authors: Jianghui Cao,
Fang Zhao,
Weixin Guan,
Xiaoxuan Yang,
Qidong Zhao,
Liguo Gao,
Xuefeng Ren,
Gang Wu,
Anmin Liu Tags: Review Source Type: research
Zinc Deficiency Decreases Neurite Extension via CRMP2 Signal Pathway
In conclusion, this study is the first to demonstrate that CRMP signaling is involved in the suppression of neurite outgrowth by low zinc.PMID:38583951 | DOI:10.1248/bpb.b24-00019 (Source: Biological and Pharmaceutical Bulletin)
Source: Biological and Pharmaceutical Bulletin - April 7, 2024 Category: Drugs & Pharmacology Authors: Hisaka Kurita Misa Ueda Miyu Kimura Ayu Okuda Kazuki Ohuchi Isao Hozumi Masatoshi Inden Source Type: research
GLUT3 transcriptional activation by ZEB1 fuels the Warburg effect and promotes ovarian cancer progression
This study explores the role of glucose transporter 3 (GLUT3) driven by zinc finger E-box-binding homeobox 1 (ZEB1) in OvCa progression and metastasis. Specifically, this study explored whether ZEB1 promotes glycolysis and assessed the potential involvement of GLUT3 in this process in OvCa cells. Our findings revealed that ZEB1 and GLUT3 were excessively expressed and closely correlated in OvCa. Mechanistically, ZEB1 activates the transcription of GLUT3 by binding to its promoter region. Increased expression of GLUT3 driven by ZEB1 dramatically enhances glycolysis, and thus fuels Warburg Effect to promote OvCa progression ...
Source: Biochimica et Biophysica Acta - April 7, 2024 Category: Biochemistry Authors: Furong Lin Lin Ma Shengnan Yu Jing Lin Zhenzhen Xu Hailong Xia Youyi Song Wang Huang Yiling Wu Ying Chen Xiyao Liu Junjie Xia Xiumin Huang Source Type: research
Activating the Intrinsic Zincophilicity of PAM Hydrogel to Stabilize the Metal-Electrolyte Dynamic Interface for Stable and Long-Life Zinc Metal Batteries
ChemSusChem. 2024 Apr 7:e202400479. doi: 10.1002/cssc.202400479. Online ahead of print.ABSTRACTAs a potential material to solve rampant dendrites and hydrogen evolution reaction (HER) problem of aqueous zinc metal batteries (AZMB), hydrogel electrolytes usually require additional additives or multi-molecular network strategies to solve existing problems of ionic conductivity, mechanical properties and interface stability. However, the intrinsic zincophilic properties of the gel itself are widely neglected leading to the addition of additional molecules and the complexity of the preparation process. In this work, we innovat...
Source: ChemSusChem - April 7, 2024 Category: Chemistry Authors: Kangli Wang Qingyuan Wang Yumeng Liu Zidong Zhang Peng Cai Haomiao Li Min Zhou Wei Wang Kai Jiang Source Type: research
BjussuMP-II, a venom metalloproteinase, induces the release and cleavage of pro-inflammatory cytokines and disrupts human umbilical vein endothelial cells
This study aimed to investigate BjussuMP-II's effects on human umbilical vein endothelial cells (HUVEC), focusing on viability, detachment, adhesion, release, and cleavage of TNF-α, IL-1β, IL-6, IL-8, and IL-10. HUVEC were incubated with BjussuMP-II (1.5-50 μg/mL) for 3-24 h. Viability was determined using LDH release, MTT metabolization, and 7AAD for membrane integrity. Adhesion and detachment were assessed by incubating cells with BjussuMP-II and staining with Giemsa. Cytokines were quantified in HUVEC supernatants using EIA. TNF-α cleavage was evaluated using supernatants from PMA-stimulated cells or recombinant TNF...
Source: Chemico-Biological Interactions - April 7, 2024 Category: Molecular Biology Authors: Hallison Mota Santana Yoda Janaina Ikenohuchi Milena Daniela Souza Silva Braz Junior Campos Farias Suzanne Nery Serrath Carolina Pereira Da Silva Jo ão Gabriel Dos Santos Magalhães Larissa Faustina Cruz Daniel Gomes Cardozo Alex Ferreira E Ferreira Vald Source Type: research
GLUT3 transcriptional activation by ZEB1 fuels the Warburg effect and promotes ovarian cancer progression
This study explores the role of glucose transporter 3 (GLUT3) driven by zinc finger E-box-binding homeobox 1 (ZEB1) in OvCa progression and metastasis. Specifically, this study explored whether ZEB1 promotes glycolysis and assessed the potential involvement of GLUT3 in this process in OvCa cells. Our findings revealed that ZEB1 and GLUT3 were excessively expressed and closely correlated in OvCa. Mechanistically, ZEB1 activates the transcription of GLUT3 by binding to its promoter region. Increased expression of GLUT3 driven by ZEB1 dramatically enhances glycolysis, and thus fuels Warburg Effect to promote OvCa progression ...
Source: Biochimica et Biophysica Acta - April 7, 2024 Category: Biochemistry Authors: Furong Lin Lin Ma Shengnan Yu Jing Lin Zhenzhen Xu Hailong Xia Youyi Song Wang Huang Yiling Wu Ying Chen Xiyao Liu Junjie Xia Xiumin Huang Source Type: research
