Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance
In conclusion, our results demonstrate the potential of vitamin C as a potential therapeutic choice for RA.PMID:38599880 | DOI:10.5582/bst.2024.01037 (Source: BioScience Trends)
Source: BioScience Trends - April 10, 2024 Category: Biomedical Science Authors: Yanjie Zhang Sibin Zhen Hao Xu Songfang Sun Ziwei Wang Mian Li Liang Zou Yangyang Zhang Yan Zhao Yazhou Cui Jinxiang Han Source Type: research
Systematic Review of the roles of Inositol and Vitamin D in improving fertility among patients with Polycystic Ovary Syndrome
Clin Exp Reprod Med. 2024 Apr 11. doi: 10.5653/cerm.2023.06485. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among reproductive-age women. As a leading cause of anovulatory infertility, it complicates fertility treatments, including in vitro fertilization. The widely accepted 2003 Rotterdam diagnostic criteria for PCOS include sub-phenotypes based on variations in androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. In this systematic review, we examined the impacts of inositol and vitamin D on fertility in PCOS. Adhering to the Preferred ...
Source: Clinical and Experimental Reproductive Medicine - April 10, 2024 Category: Reproduction Medicine Authors: Gitika Katyal Gursharan Kaur Hafsa Ashraf Adiprasad Bodapati Ayesha Hanif Donatus Kaine Okafor Safeera Khan Source Type: research
Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance
In conclusion, our results demonstrate the potential of vitamin C as a potential therapeutic choice for RA.PMID:38599880 | DOI:10.5582/bst.2024.01037 (Source: BioScience Trends)
Source: BioScience Trends - April 10, 2024 Category: Biomedical Science Authors: Yanjie Zhang Sibin Zhen Hao Xu Songfang Sun Ziwei Wang Mian Li Liang Zou Yangyang Zhang Yan Zhao Yazhou Cui Jinxiang Han Source Type: research
Systematic Review of the roles of Inositol and Vitamin D in improving fertility among patients with Polycystic Ovary Syndrome
Clin Exp Reprod Med. 2024 Apr 11. doi: 10.5653/cerm.2023.06485. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among reproductive-age women. As a leading cause of anovulatory infertility, it complicates fertility treatments, including in vitro fertilization. The widely accepted 2003 Rotterdam diagnostic criteria for PCOS include sub-phenotypes based on variations in androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. In this systematic review, we examined the impacts of inositol and vitamin D on fertility in PCOS. Adhering to the Preferred ...
Source: Clinical and Experimental Reproductive Medicine - April 10, 2024 Category: Reproduction Medicine Authors: Gitika Katyal Gursharan Kaur Hafsa Ashraf Adiprasad Bodapati Ayesha Hanif Donatus Kaine Okafor Safeera Khan Source Type: research
Irradiated riboflavin over nonradiated one: Potent antimigratory, antiproliferative and cytotoxic effects on glioblastoma cells
In conclusion, radiated riboflavin clearly demonstrates superior antiproliferative and apoptotic effects on C6 cells at lower doses compared to nonradiated riboflavin.PMID:38597418 | PMC:PMC11005454 | DOI:10.1111/jcmm.18288 (Source: J Cell Mol Med)
Source: J Cell Mol Med - April 10, 2024 Category: Molecular Biology Authors: Sedat Kacar Ceyhan Hacioglu Fatih Kar Source Type: research
Research progress and future development potential of Flammulina velutipes polysaccharides in the preparation process, structure analysis, biology, and pharmacology: A review
Int J Biol Macromol. 2024 Apr 8:131467. doi: 10.1016/j.ijbiomac.2024.131467. Online ahead of print.ABSTRACTIn recent years, Flammulina velutipes (F. velutipes) has attracted consequential attention in various research fields due to its rich composition of proteins, vitamins, amino acids, polysaccharides, and polyphenols. F. velutipes polysaccharides (FVPs) are considered as key bioactive components of F. velutipes, demonstrating multiple physiological activities, including immunomodulatory, anti-inflammatory, and antibacterial properties. Moreover, they offer health benefits such as antioxidant and anti-aging properties, w...
Source: International Journal of Biological Macromolecules - April 10, 2024 Category: Biochemistry Authors: Shiying Ye Yi Gao Xiangyan Hu Jiye Cai Shaowei Sun Jinhuan Jiang Source Type: research
Biophysical insight into the binding mechanism of epigallocatechin-3-gallate and cholecalciferol to albumin and its preventive effect against AGEs formation: An in vitro and in silico approach
This article focusses on the interaction and antiglycating potential of (-)-Epigallocatechin-3-gallate (EGCG) and vitamin D in combination using various techniques. The formation of the HSA-EGCG and HSA-vitamin D complex was confirmed by UV and fluorescence spectroscopy. Thermodynamic analysis verified the spontaneity of reaction, and presence of hydrogen bonds and van der Waals interactions. FRET confirms high possibility of energy transfer. Cumulative antiglycation resulted in almost 60 % prevention in AGEs formation, decreased alterations at lysine and arginine, and reduced protein carbonylation. Secondary and tertiary ...
Source: International Journal of Biological Macromolecules - April 10, 2024 Category: Biochemistry Authors: Sana Siddiqui Rizwan Ahmad Yusra Ahmad Abul Faiz Faizy Shagufta Moin Source Type: research
Vitamin B < sub > 6 < /sub > alleviates chronic sleep deprivation-induced hippocampal ferroptosis through CBS/GSH/GPX4 pathway
Biomed Pharmacother. 2024 Apr 9;174:116547. doi: 10.1016/j.biopha.2024.116547. Online ahead of print.ABSTRACTSeveral studies have found that sleep deprivation (SD) can lead to neuronal ferroptosis and affect hippocampal function. However, there are currently no effective interventions. Vitamin B6 is a co-factor for key enzymes in the transsulfuration pathway which is critical for maintaining cell growth in the presence of cysteine deprivation. The results showed that SD inhibited cystine-glutamate antiporter light chain subunit xCT protein expression and caused cysteine deficiency, which reduced the synthesis of the glutat...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 10, 2024 Category: Drugs & Pharmacology Authors: Man Yuan Feng Wang Tieqiang Sun Xiangyu Bian Yuxian Zhang Changjiang Guo Lixia Yu Zhanxin Yao Source Type: research
Co-administration of "L-Lysine, Vitamin C, and Zinc" increased the antioxidant activity, decreased insulin resistance, and improved lipid profile in streptozotocin-induced diabetic rats
CONCLUSIONS: The results of this study indicated that co-administration of Lys, a chemical chaperone, with two antioxidants (VC and Zn) potentiates its antidiabetic effects and prevent diabetic complications in rat model of diabetes.PMID:38599057 | DOI:10.1016/j.biopha.2024.116525 (Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie)
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 10, 2024 Category: Drugs & Pharmacology Authors: Mostafa Yousefian Saeid Abedimanesh Amirhossein Yadegar Manouchehr Nakhjavani S Zahra Bathaie Source Type: research
Vitamin C alleviates rheumatoid arthritis by modulating gut microbiota balance
In conclusion, our results demonstrate the potential of vitamin C as a potential therapeutic choice for RA.PMID:38599880 | DOI:10.5582/bst.2024.01037 (Source: BioScience Trends)
Source: BioScience Trends - April 10, 2024 Category: Biomedical Science Authors: Yanjie Zhang Sibin Zhen Hao Xu Songfang Sun Ziwei Wang Mian Li Liang Zou Yangyang Zhang Yan Zhao Yazhou Cui Jinxiang Han Source Type: research
Irradiated riboflavin over nonradiated one: Potent antimigratory, antiproliferative and cytotoxic effects on glioblastoma cells
In conclusion, radiated riboflavin clearly demonstrates superior antiproliferative and apoptotic effects on C6 cells at lower doses compared to nonradiated riboflavin.PMID:38597418 | PMC:PMC11005454 | DOI:10.1111/jcmm.18288 (Source: Molecular Medicine)
Source: Molecular Medicine - April 10, 2024 Category: Molecular Biology Authors: Sedat Kacar Ceyhan Hacioglu Fatih Kar Source Type: research
Systematic Review of the roles of Inositol and Vitamin D in improving fertility among patients with Polycystic Ovary Syndrome
Clin Exp Reprod Med. 2024 Apr 11. doi: 10.5653/cerm.2023.06485. Online ahead of print.ABSTRACTPolycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder among reproductive-age women. As a leading cause of anovulatory infertility, it complicates fertility treatments, including in vitro fertilization. The widely accepted 2003 Rotterdam diagnostic criteria for PCOS include sub-phenotypes based on variations in androgen excess, ovulatory dysfunction, and polycystic ovarian morphology. In this systematic review, we examined the impacts of inositol and vitamin D on fertility in PCOS. Adhering to the Preferred ...
Source: Clinical and Experimental Reproductive Medicine - April 10, 2024 Category: Reproduction Medicine Authors: Gitika Katyal Gursharan Kaur Hafsa Ashraf Adiprasad Bodapati Ayesha Hanif Donatus Kaine Okafor Safeera Khan Source Type: research
Biophysical insight into the binding mechanism of epigallocatechin-3-gallate and cholecalciferol to albumin and its preventive effect against AGEs formation: An in vitro and in silico approach
This article focusses on the interaction and antiglycating potential of (-)-Epigallocatechin-3-gallate (EGCG) and vitamin D in combination using various techniques. The formation of the HSA-EGCG and HSA-vitamin D complex was confirmed by UV and fluorescence spectroscopy. Thermodynamic analysis verified the spontaneity of reaction, and presence of hydrogen bonds and van der Waals interactions. FRET confirms high possibility of energy transfer. Cumulative antiglycation resulted in almost 60 % prevention in AGEs formation, decreased alterations at lysine and arginine, and reduced protein carbonylation. Secondary and tertiary ...
Source: International Journal of Biological Macromolecules - April 10, 2024 Category: Biochemistry Authors: Sana Siddiqui Rizwan Ahmad Yusra Ahmad Abul Faiz Faizy Shagufta Moin Source Type: research
Research progress and future development potential of Flammulina velutipes polysaccharides in the preparation process, structure analysis, biology, and pharmacology: A review
Int J Biol Macromol. 2024 Apr 8:131467. doi: 10.1016/j.ijbiomac.2024.131467. Online ahead of print.ABSTRACTIn recent years, Flammulina velutipes (F. velutipes) has attracted consequential attention in various research fields due to its rich composition of proteins, vitamins, amino acids, polysaccharides, and polyphenols. F. velutipes polysaccharides (FVPs) are considered as key bioactive components of F. velutipes, demonstrating multiple physiological activities, including immunomodulatory, anti-inflammatory, and antibacterial properties. Moreover, they offer health benefits such as antioxidant and anti-aging properties, w...
Source: International Journal of Biological Macromolecules - April 10, 2024 Category: Biochemistry Authors: Shiying Ye Yi Gao Xiangyan Hu Jiye Cai Shaowei Sun Jinhuan Jiang Source Type: research
