Integrated analysis of intestinal microbiota and transcriptome reveals that a coordinated interaction of the endocrine, immune system and gut microbiota response to heat stress in Litopenaeus vannamei
This study revealed the response mechanism of L. vannamei to acute heat stress and potentially provided a theoretical foundation for future research on shrimp environmental adaptations.PMID:38582249 | DOI:10.1016/j.dci.2024.105176 (Source: Developmental and Comparative Immunology)
Source: Developmental and Comparative Immunology - April 6, 2024 Category: Allergy & Immunology Authors: Guowei Liao Wanqi Wang Jiaoping Yu Jingping Li Yumeng Yan Haolin Liu Bing Chen Lanfen Fan Source Type: research
Longitudinal changes in adverse effects reporting in multiple dietary supplement classifications: The US military dietary supplement use study
In conclusion, AEs reported at baseline did not deter many participants from using DSs in the follow-up period, and many SMs reporting AEs at baseline continued reporting them at follow-up.PMID:38582347 | DOI:10.1016/j.fct.2024.114635 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - April 6, 2024 Category: Food Science Authors: Joseph J Knapik Daniel W Trone Ryan A Steelman Harris R Lieberman Source Type: research
Feeding strategies for Sporosarcina pasteurii cultivation unlock more efficient production of ureolytic biomass for MICP
This study focusses on fed-batch cultivation of S. pasteurii DSM33. The study distinguishes between limited fed-batch cultivation and extended batch cultivation. Simply feeding glucose to a S. pasteurii culture does not seem beneficial. However, it was exploited that S. pasteurii is auxotrophic for two vitamins and amino acids. Limited fed-batch cultivation was accomplished by feeding the necessary vitamins or amino acids to a culture lacking them. Feeding nicotinic acid to a nicotinic acid deprived culture resulted in a 24% increase of the specific urease activity compared to a fed culture without nicotinic acid limitatio...
Source: Biotechnology Journal - April 6, 2024 Category: Biotechnology Authors: Fr édéric M Lapierre Robert Huber Source Type: research
Influence of intensity ultrasound on rheological properties and bioactive compounds of araticum (Annona crassiflora) juice
Ultrason Sonochem. 2024 Apr 3;105:106868. doi: 10.1016/j.ultsonch.2024.106868. Online ahead of print.ABSTRACTThe use of extracts rich in bioactive compounds is becoming increasingly common in the food, cosmetics, and pharmaceutical industries for the production of functional products. Araticum is a potential fruit to be analyzed due to its content of phenolic compounds, carotenoids and vitamins, with antioxidant properties. Therefore, this study aimed to investigate the effect of ultrasound on total phenolic compounds, total carotenoids, ascorbic acid, color, turbidity and rheology in araticum juice. Response surface metho...
Source: Ultrasonics Sonochemistry - April 6, 2024 Category: Chemistry Authors: Jhenifer Cristina Carvalho Santos Jefferson Luiz Gomes Correa Maria Luiza Bianchetti Furtado Larissa Carolina de Morais Soraia Vilela Borges Cassiano Rodrigues de Oliveira Jaime Vilela de Resende Let ícia Fernandes de Oliveira Source Type: research
Microalgae/cyanobacteria: the potential green future of vitamin B12 production
(Source: Critical Reviews in Food Science and Nutrition)
Source: Critical Reviews in Food Science and Nutrition - April 6, 2024 Category: Nutrition Authors: Durdakova, Michaela Kolackova, Martina Janova, Anna Krystofova, Olga Adam, Vojtech Huska, Dalibor Source Type: research
Nutrition Assessment and Management in Celiac Disease
Celiac disease (CeD) is the most common immune condition affecting the gastrointestinal tract; it is triggered by gluten and the only available treatment is a strict gluten-free diet (GFD). Therefore, for patients with CeD, adopting a GFD is not a lifestyle choice. The major problem is that a GFD is restrictive and, like all restrictive diets, it has the potential for adverse nutritional outcomes, especially if adopted for a long term. It is well known that GFD can be nutritionally inadequate and is frequently associated with vitamin and mineral deficiencies; it is also associated with excessive sugar and fat intake, parti...
Source: Gastroenterology - April 6, 2024 Category: Gastroenterology Authors: M. Ines Pinto-Sanchez, Jedid-Jah Blom, Peter R. Gibson, David Armstrong Tags: Invited 2024 13th Issue: Celiac Disease Source Type: research
Evaluation of modified fixed dose four-factor prothrombin complex concentrate for warfarin reversal
AbstractNon-activated four-factor prothrombin complex concentrate (4 F-PCC) has emerged as the preferred reversal strategy for patients on warfarin with life-threatening bleeding. Current dosing recommendations for 4 F-PCC require pre-treatment international normalized ratio (INR) and bodyweight values, resulting in ordering and administration delays. Studies have shown that alternative dosing regimens are safe and efficacious. This retrospective, single-center, pre- and post-protocol analysis was conducted to assess the efficacy of a pharmacist driven modified fixed-dose 4 F-PCC regimen versus package insert weight- a...
Source: Journal of Thrombosis and Thrombolysis - April 6, 2024 Category: Hematology Source Type: research
Nutrition assessment and management in celiac disease.
CeD is the most common immune condition affecting the gastrointestinal tract; it is triggered by gluten and the only available treatment is a strict gluten-free diet (GFD). Therefore, for patients with CeD, adopting a GFD is not a lifestyle choice. The major problem is that a GFD is restrictive, and like all restrictive diets, it has the potential for adverse nutritional outcomes, especially if adopted for a long-term. It is well known that GFD can be nutritionally inadequate and is frequently associated with vitamin and mineral deficiencies; it is, also, associated with excessive sugar and fat intake, particularly when gl...
Source: Gastroenterology - April 6, 2024 Category: Gastroenterology Authors: M Ines Pinto-Sanchez, Jedid-Jah Blom, Peter R. Gibson, David Armstrong Tags: Invited 2024 13th Issue: Celiac Disease Source Type: research
Evaluation of modified fixed dose four-factor prothrombin complex concentrate for warfarin reversal
AbstractNon-activated four-factor prothrombin complex concentrate (4 F-PCC) has emerged as the preferred reversal strategy for patients on warfarin with life-threatening bleeding. Current dosing recommendations for 4 F-PCC require pre-treatment international normalized ratio (INR) and bodyweight values, resulting in ordering and administration delays. Studies have shown that alternative dosing regimens are safe and efficacious. This retrospective, single-center, pre- and post-protocol analysis was conducted to assess the efficacy of a pharmacist driven modified fixed-dose 4 F-PCC regimen versus package insert weight- a...
Source: Journal of Thrombosis and Thrombolysis - April 6, 2024 Category: Hematology Source Type: research
Molecules, Vol. 29, Pages 1642: Phytochemical Constituent Analysis of Phyllanthus emblica L. Fruit Nanoherbals by LC-HRMS and Their Antimutagenic Activity and Teratogenic Effects
This study aims to determine the phytochemical constituents of Phyllanthus emblica L. fruit nanoherbals by LC-HRMS analysis and their antimutagenic activity and teratogenic effects. The study commenced by producing nanoherbal extracts from P. emblica fruit. The phytochemical composition of these extracts was then analyzed using LC-HRMS. The nanoherbal extracts were also tested for their ability to prevent mutations, as indicated by a reduction in micronuclei observed in mouse femur bone marrow smear preparations. The teratogenicity test involved administering the P. emblica fruit nanoherbal at 100, 500, and 1000 mg/kg BW d...
Source: Molecules - April 6, 2024 Category: Chemistry Authors: Masfria Aminah Dalimunthe Nurul Suci Hafid Syahputra Tags: Article Source Type: research
Use of complementary medicine and its association with SARS-CoV-2 vaccination during the COVID-19 pandemic: a longitudinal cohort study
CONCLUSION: While complementary medicine is increasingly used, it is rarely discussed with primary care physicians. Complementary medicine use, especially for COVID-19 prevention, is associated with COVID-19 vaccination status. Communication between physicians, patients, and complementary medicine therapists is encouraged to facilitate a truly holistic approach to making a shared decision based on the best available information.PMID:38579302 | DOI:10.57187/s.3505 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Mayssam Nehme Olivia Braillard Pierre-Yves Rodondi Idris Guessous Source Type: research
Use of complementary medicine and its association with SARS-CoV-2 vaccination during the COVID-19 pandemic: a longitudinal cohort study
CONCLUSION: While complementary medicine is increasingly used, it is rarely discussed with primary care physicians. Complementary medicine use, especially for COVID-19 prevention, is associated with COVID-19 vaccination status. Communication between physicians, patients, and complementary medicine therapists is encouraged to facilitate a truly holistic approach to making a shared decision based on the best available information.PMID:38579302 | DOI:10.57187/s.3505 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - April 5, 2024 Category: General Medicine Authors: Mayssam Nehme Olivia Braillard Pierre-Yves Rodondi Idris Guessous Source Type: research
The effect of administering preprocedural VITamin K on the international normalized ratio in patients anticoagulated with ACEnocoumarol (VITKACE-study)
CONCLUSIONS: Using oral vitamin K while patients continue acenocoumarol intake is an effective way to adequately lower INR before an invasive procedure. Low amount of bleeding complications and absence of thromboembolic complications suggest that this is a safe strategy. The INR-values returned gradually to therapeutic range after the procedure, probably contributing to the observed low bleeding rate.PMID:38580096 | DOI:10.1016/j.jtha.2024.03.016 (Source: Thrombosis and Haemostasis)
Source: Thrombosis and Haemostasis - April 5, 2024 Category: Hematology Authors: Stella Bijkerk Harm J Lourens Wout G N Mares Corine A van Kampen Maurits J van der Veen Henk J Adriaansen Erik D Ponfoort Barbara Festen G Wouter Westendorp J örgen M P Rovers Gerie M C Groot Hans-Peter R Bootsma Linde M Amelung Sander Bins Gerjo Velders Source Type: research
Energy drink consumption among medical students in Jordan - prevalence, attitudes, and associated factors: a cross-sectional study
CONCLUSION: The prevalence of energy drink consumption among medical students in Jordan is high, with factors such as social influences, lifestyle behaviors, and academic pressure being significant contributors. This study highlights the need for interventions to promote healthy behaviors and raise awareness about the potential harms of ED among medical students.PMID:38576977 | PMC:PMC10990385 | DOI:10.1097/MS9.0000000000001791 (Source: Annals of Medicine)
Source: Annals of Medicine - April 5, 2024 Category: Internal Medicine Authors: Nuha W Qasem Omar M Al-Omoush Zaid M Al Ammouri Nour M Alnobani Mohamed M Abdallah Abdullah N Khateeb Michael H Habash Ruba A Hrout Source Type: research
The Hepatocurative Effects of < em > Zanthoxylum zanthoxyloides < /em > Alkaloids on Tetrachloromethane-Induced Hepatotoxicity on Albino Rats
Indian J Clin Biochem. 2024 Apr;39(2):188-196. doi: 10.1007/s12291-022-01095-z. Epub 2022 Nov 12.ABSTRACTThe study investigated the hepatocurative activity of the bulk alkaloids of Zanthoxylum zanthoxyloides in a tetrachloromethane (CCl4)-induced hepatotoxicity model in rats. The hepatocurative activity of the alkaloids at 200, 400 and 600 mg/kg doses was demonstrated by the assay of both enzymic and non-enzymic parameters. Sections of the liver were also subjected to histological examinations. Mapping techniques and data visualization approaches were adopted in finding relationships between the enzymic and non-enzymic par...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Thecla Okeahunwa Ayoka Ngwu Nwachukwu Aloysius Chinedu Ene Chidi Uzoma Igwe Charles Okeke Nnadi Source Type: research
