Targeting SRD5A1 and MMP-2/NLRP3/TGF- β1 axis alleviates the amlodipine-induced gingival hyperplasia in rats: Emerging role of saw palmetto and folic acid
Food Chem Toxicol. 2024 May 11;189:114731. doi: 10.1016/j.fct.2024.114731. Online ahead of print.ABSTRACTSaw palmetto (SAW), the herbal drug used to treat prostatic hyperplasia, exerts its antiproliferative effects by blocking steroid 5 alpha-reductase (SRD5A1) activity, that has also been involved in gingival hyperplasia (GH) pathogenesis. Concurrently, folic acid (FA) could reduce GH prevalence via its antioxidant and anti-inflammatory effects. Thus, this study tended to assess the potential therapeutic efficacy of SAW, alone and along with FA, against amlodipine-induced gingival inflammation and overgrowth in rats. Rats...
Source: Food and Chemical Toxicology - May 13, 2024 Category: Food Science Authors: Manar Mohammed El Tabaa Mahmoud Moustafa Aboud Anis Anis Eman Rashad Samia Salem Sokar Source Type: research
Low Vitamin A Status: A Potential Limiting Factor for Hemoglobin Improvement to Iron –Folic Acid Supplementation in Adolescent Girls with Iron Deficiency Anemia
In conclusion, low vitamin A status is a significant limiting factor contributing to the inadequate Hb increment during IFA supplementation, which may be particularly relevant in regions where vitamin-A deficiency is still a public health concern. (Source: Indian Journal of Clinical Biochemistry)
Source: Indian Journal of Clinical Biochemistry - May 11, 2024 Category: Biochemistry Source Type: research
Influence of folic acid and vitamin B12 supplementation on arsenic methylation: A double-blinded, placebo-controlled trial in Bangladeshi children
CONCLUSION: This RCT confirms that FA + B12 supplementation increases arsenic methylation in children as reflected by decreased MMAs and increased DMAs in blood and urine. Nutritional interventions may improve arsenic methylation and elimination in children, potentially reducing arsenic toxicity while also improving nutritional status.PMID:38728816 | DOI:10.1016/j.envint.2024.108715 (Source: Environment International)
Source: Environment International - May 10, 2024 Category: Environmental Health Authors: Irene Martinez-Morata Faruque Parvez Haotian Wu Mahbubul Eunus Jeff Goldsmith Vesna Ilievski Vesna Slavkovich Olgica Balac Chiugo Izuchukwu Ronald A Glabonjat Tyler Ellis Mohammad Nasir Uddin Tariqul Islam Anwar Sadat Arif Alexander van Geen Ana Navas-Aci Source Type: research
Influence of folic acid and vitamin B12 supplementation on arsenic methylation: A double-blinded, placebo-controlled trial in Bangladeshi children
CONCLUSION: This RCT confirms that FA + B12 supplementation increases arsenic methylation in children as reflected by decreased MMAs and increased DMAs in blood and urine. Nutritional interventions may improve arsenic methylation and elimination in children, potentially reducing arsenic toxicity while also improving nutritional status.PMID:38728816 | DOI:10.1016/j.envint.2024.108715 (Source: Environment International)
Source: Environment International - May 10, 2024 Category: Environmental Health Authors: Irene Martinez-Morata Faruque Parvez Haotian Wu Mahbubul Eunus Jeff Goldsmith Vesna Ilievski Vesna Slavkovich Olgica Balac Chiugo Izuchukwu Ronald A Glabonjat Tyler Ellis Mohammad Nasir Uddin Tariqul Islam Anwar Sadat Arif Alexander van Geen Ana Navas-Aci Source Type: research
A real-world cross-sectional study evaluating the role of an oral amino acid-based supplement in nutrient intake by preschoolers on a cow's milk elimination diet
CONCLUSIONS: The use of a complete oral amino acid-based supplement has a positive effect on the diet quality of preschoolers on cow's milk elimination diet because of food allergy, promoting higher intake of energy, calcium, vitamin D, and other essential nutrients.PMID:38721954 | DOI:10.15586/aei.v52i3.1053 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - May 9, 2024 Category: Allergy & Immunology Authors: Vanessa Cristina de Castro Rodrigues Thaysa Mau és Cezar Camila Leonel Mendes de Abreu Adriana Sanudo Mauro Batista de Morais Source Type: research
A real-world cross-sectional study evaluating the role of an oral amino acid-based supplement in nutrient intake by preschoolers on a cow's milk elimination diet
CONCLUSIONS: The use of a complete oral amino acid-based supplement has a positive effect on the diet quality of preschoolers on cow's milk elimination diet because of food allergy, promoting higher intake of energy, calcium, vitamin D, and other essential nutrients.PMID:38721954 | DOI:10.15586/aei.v52i3.1053 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - May 9, 2024 Category: Allergy & Immunology Authors: Vanessa Cristina de Castro Rodrigues Thaysa Mau és Cezar Camila Leonel Mendes de Abreu Adriana Sanudo Mauro Batista de Morais Source Type: research
A real-world cross-sectional study evaluating the role of an oral amino acid-based supplement in nutrient intake by preschoolers on a cow's milk elimination diet
CONCLUSIONS: The use of a complete oral amino acid-based supplement has a positive effect on the diet quality of preschoolers on cow's milk elimination diet because of food allergy, promoting higher intake of energy, calcium, vitamin D, and other essential nutrients.PMID:38721954 | DOI:10.15586/aei.v52i3.1053 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - May 9, 2024 Category: Allergy & Immunology Authors: Vanessa Cristina de Castro Rodrigues Thaysa Mau és Cezar Camila Leonel Mendes de Abreu Adriana Sanudo Mauro Batista de Morais Source Type: research
A real-world cross-sectional study evaluating the role of an oral amino acid-based supplement in nutrient intake by preschoolers on a cow's milk elimination diet
CONCLUSIONS: The use of a complete oral amino acid-based supplement has a positive effect on the diet quality of preschoolers on cow's milk elimination diet because of food allergy, promoting higher intake of energy, calcium, vitamin D, and other essential nutrients.PMID:38721954 | DOI:10.15586/aei.v52i3.1053 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - May 9, 2024 Category: Allergy & Immunology Authors: Vanessa Cristina de Castro Rodrigues Thaysa Mau és Cezar Camila Leonel Mendes de Abreu Adriana Sanudo Mauro Batista de Morais Source Type: research
A real-world cross-sectional study evaluating the role of an oral amino acid-based supplement in nutrient intake by preschoolers on a cow's milk elimination diet
CONCLUSIONS: The use of a complete oral amino acid-based supplement has a positive effect on the diet quality of preschoolers on cow's milk elimination diet because of food allergy, promoting higher intake of energy, calcium, vitamin D, and other essential nutrients.PMID:38721954 | DOI:10.15586/aei.v52i3.1053 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - May 9, 2024 Category: Allergy & Immunology Authors: Vanessa Cristina de Castro Rodrigues Thaysa Mau és Cezar Camila Leonel Mendes de Abreu Adriana Sanudo Mauro Batista de Morais Source Type: research
A real-world cross-sectional study evaluating the role of an oral amino acid-based supplement in nutrient intake by preschoolers on a cow's milk elimination diet
CONCLUSIONS: The use of a complete oral amino acid-based supplement has a positive effect on the diet quality of preschoolers on cow's milk elimination diet because of food allergy, promoting higher intake of energy, calcium, vitamin D, and other essential nutrients.PMID:38721954 | DOI:10.15586/aei.v52i3.1053 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - May 9, 2024 Category: Allergy & Immunology Authors: Vanessa Cristina de Castro Rodrigues Thaysa Mau és Cezar Camila Leonel Mendes de Abreu Adriana Sanudo Mauro Batista de Morais Source Type: research
A real-world cross-sectional study evaluating the role of an oral amino acid-based supplement in nutrient intake by preschoolers on a cow's milk elimination diet
CONCLUSIONS: The use of a complete oral amino acid-based supplement has a positive effect on the diet quality of preschoolers on cow's milk elimination diet because of food allergy, promoting higher intake of energy, calcium, vitamin D, and other essential nutrients.PMID:38721954 | DOI:10.15586/aei.v52i3.1053 (Source: Allergologia et Immunopathologia)
Source: Allergologia et Immunopathologia - May 9, 2024 Category: Allergy & Immunology Authors: Vanessa Cristina de Castro Rodrigues Thaysa Mau és Cezar Camila Leonel Mendes de Abreu Adriana Sanudo Mauro Batista de Morais Source Type: research
A Case of Refractory Anemia in Patient of Chronic Kidney Disease and the Challenges in its Management
J Assoc Physicians India. 2023 Oct;71(10):94-95. doi: 10.59556/japi.71.0331.ABSTRACTAnemia is a common complication of chronic kidney disease (CKD) that has been classically attributed to inadequate production of endogenous erythropoietin.1 Though there are many other common causes of refractory anemia in CKD like iron deficiency, vitamin B12, and folic acid deficiency, noncompliance to dialysis and erythropoietin therapy rare causes like blood loss, bone marrow failure, infections causing aplastic crisis like CMV, parvovirus B19 should be ruled out. Parvovirus has an extreme tropism for erythroid cells and is an uncommon ...
Source: Journal of the Association of Physicians of India - May 8, 2024 Category: General Medicine Authors: Komal Gade Charulata Londhe Sangeeta Pednekar Dharmendra Pandey Namita Padwal Ashish Agrwal Source Type: research
Efficacy of multivitamin support following bariatric surgery in patients with obesity: a prospective observational study
CONCLUSION: Following VSG or RYGB, Bariatrifast administration was associated with normal values of essential micronutrients, and it was well-tolerated without evidence of gastrointestinal side effects. Clinical Trial Registration ClinicalTrials.gov, identifiers NCT06152965.PMID:38714632 | PMC:PMC11076347 | DOI:10.1007/s40519-024-01655-7 (Source: Eating and weight disorders : EWD)
Source: Eating and weight disorders : EWD - May 7, 2024 Category: Eating Disorders & Weight Management Authors: Alessio Basolo Susanna Bechi Genzano Jacopo Vitti Guido Salvetti Donatella Gilio Giovanni Ceccarini Giovanna Scartabelli Chita Lippi Rosario Bellini Rudi Mancini Simone D'Imporzano Carlo Moretto Valentina Angeli Daniela Troiani Paola Fierabracci Roberta J Source Type: research
160 folic acid deficiency exacerbates biliary inflammation in primary biliary cholangitis by promoting cholangiocyte senescence
(Source: Gastroenterology)
Source: Gastroenterology - May 6, 2024 Category: Gastroenterology Authors: Hao Jia, Xue Zhang, Hui Yang, Xiaoyi Wang, Hongyu Chu, Man Liu, Bangmao Wang, Ying Ran, Long Li, Lu Zhou Tags: AASLD Abstracts Source Type: research
Effect of multiple micronutrient-fortified bouillon on micronutrient status among women and children in the Northern Region of Ghana: Protocol for the Condiment Micronutrient Innovation Trial (CoMIT), a community-based randomized controlled trial
This study aims to evaluate the impact of multiple micronutrient-fortified bouillon cubes, compared to control bouillon cubes (fortified with iodine only), on micronutrient status and hemoglobin concentrations among lactating and non-lactating WRA and young children in northern Ghana. MethodsThis randomized, controlled doubly-masked trial will be conducted in the Kumbungu and Tolon districts in the Northern Region of Ghana, where prior data indicate multiple micronutrient deficiencies are common. Participants will be: 1) non-pregnant non-lactating WRA (15 –49 y), 2) children 2–5 y, and 3) non-pregnant lactating women 4...
Source: PLoS One - May 6, 2024 Category: Biomedical Science Authors: Reina Engle-Stone Source Type: research
