miRNA Therapy Slows Cancer Growth
Scientists at Purdue University have developed a microRNA therapy designed to slow tumor growth. The technology takes advantage of the tendency of several cancer types to express an excess of surface receptors that bind folate (vitamin B9) and draw it into the cell interior. By attaching the microRNA strand to a folate molecule, the researchers could target it to cancer cells. This targeting specificity is advantageous in reducing the potential for side-effects elsewhere in the body, and in reducing the required dose to achieve a tangible anti-cancer effect. The researchers hope that the treatment will expand the therapeut...
Source: Medgadget - October 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Genetics Oncology Source Type: blogs
What's new in midwifery - 23rd April 2021
#whatsnewinmidwifery is a tag I shall use on Twitter (@knockels) if retweeting things of interest. Let ' s see how that goes.Some retweeted things may be in these blogposts as well.Here are some things you might need to know.COVID-19Pregnant women to be offered the vaccine.NewsIn the news, stories about thesix week check not looking at the health of the mother, abouthealth and safety at work and pregnancy, and perhapsan indication of your future workload!And a report aboutone consequence for women attending prenatal appointments alone.One woman ’s experience of postpartum psychosis, . And related,...
Source: Browsing - April 23, 2021 Category: Databases & Libraries Tags: midwifery Source Type: blogs
Chemicals and Pregnant Women: Taking Care of Your Unborn Baby
This study is not a warning of a scary new epidemic of problems arriving with next year’s babies.
Instead, it’s a peak behind the curtain at what might be the hidden story behind the marvelous kids we already see on today’s playgrounds across the country. Most are very healthy – among the healthiest kids in history. Yes, too many are overweight. Too many have asthma. Too many have allergies. Too many have learning problems. Too many start puberty early. More than half have some chronic illness. But this isn’t slowing kids down as much as the devastating infectious diseases of the past. It is a vib...
Source: Conversations with Dr Greene - May 25, 2020 Category: Child Development Authors: Alan Greene MD Tags: Uncategorized Source Type: blogs
To screen, or not to screen (for dementia), that is still the question
A leading group of medical experts on Tuesday declined to endorse cognitive screening for older adults, fueling a debate that has simmered for years.
The U.S. Preventive Services Task Force said it could neither recommend nor oppose cognitive screening, citing insufficient scientific evidence of the practice’s benefits and harms and calling for further studies.
The task force’s work informs policies set by Medicare and private insurers. Its recommendations, an accompanying scientific statement and two editorials were published Tuesday in the Journal of the American Medical Association.
The task force’s new position c...
Source: SharpBrains - March 11, 2020 Category: Neuroscience Authors: Judith Graham at Kaiser Health News Tags: Cognitive Neuroscience Health & Wellness Alzheimer’s Disease Annual Wellness Visit cognition cognitive decline cognitive-abilities Cognitive-impairment cognitive-screening dementia geriatric psychiatrists geriatricians JAMA Jou Source Type: blogs
What can you do to reduce the risk of birth defects?
You’ve done it! You’ve taken that last birth control pill, removed your IUD, or stopped using your contraceptive method of choice. You’ve made the decision to try to conceive a pregnancy, and while this is an exciting time in your life, it can also feel overwhelming. There is so much advice around fertility and pregnancy, and sifting through it all just isn’t possible. For many mothers, their goals crystallize around ensuring that their baby is healthy.
Evidence-based steps that may prevent birth defects
January is Birth Defects Prevention Month, so we want to focus on things you can do to reduce the risk of birth ...
Source: Harvard Health Blog - January 22, 2020 Category: Consumer Health News Authors: Huma Farid, MD Tags: Family Planning and Pregnancy Fertility Vaccines Women's Health Source Type: blogs
What's new in midwifery - 13th November 2019
Some recent things...StatisticsBreastfeeding at 6-8 weeks after birth (Public Health England)Reproductive health: 2019 update (Official Statistics)Update of profile indicators, which include birth outcomesNHS Maternity Statistics 2018-19 (NHS Digital)Statistics on maternity activity in English hospitals, including method of onset of delivery, delivery method, place of delivery, baby ' s first feed type, maternal alcohol intake, and folic acid intake.Summary from the Embed Health Consortium Health Bulletin:Use of analgesics or anaesthetics before or during delivery has dropped;The number of all deliveries is at its lowest l...
Source: Browsing - November 13, 2019 Category: Databases & Libraries Tags: midwifery Source Type: blogs
Fight Aging! Newsletter, July 22nd 2019
This study elucidates the potential to use mitochondria from different donors (PAMM) to treat UVR stress and possibly other types of damage or metabolic malfunctions in cells, resulting in not only in-vitro but also ex-vivo applications.
Gene Therapy in Mice Alters the Balance of Macrophage Phenotypes to Slow Atherosclerosis Progression
https://www.fightaging.org/archives/2019/07/gene-therapy-in-mice-alters-the-balance-of-macrophage-phenotypes-to-slow-atherosclerosis-progression/
Atherosclerosis causes a sizable fraction of all deaths in our species. It is the generation of fatty deposits in blood vesse...
Source: Fight Aging! - July 21, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Common Dietary Supplements Have Little to No Effect on Mortality
Yet another sizable study has shown that common dietary supplements have little to no effect on late life mortality. This finding of course has to compete with the wall to wall marketing deployed by the supplement market. Researchers have been presenting data on the ineffectiveness of near all supplements of years, but it doesn't seem to reduce the enthusiasm for these products. In the past it was fairly easy to dismiss all supplements as nonsense, or at the very least causing only marginal effects that were in no way comparable to the benefits of exercise and calorie restriction, but matters are now becoming more complex....
Source: Fight Aging! - July 19, 2019 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Spasers: Nanoscale Lasers Small Enough to Destroy Cancer Cells from Within
Lasers are known to do remarkable things in medicine, but their use in targeting diseased tissue is not as widespread as everyone expected it to be decades ago. One issue is that lasers are pretty indiscriminate and traditionally have beams that are still too large for extremely fine work. Researchers at the University of Arkansas for Medical Sciences have developed a laser so small that it can fit inside a cell and shine from within. Being able to produce coherent, high power light from the interior of cells leads to all sorts of interesting applications, including up-close assessments of cells for disease and even select...
Source: Medgadget - June 14, 2019 Category: Medical Devices Authors: Medgadget Editors Tags: Nanomedicine Oncology Source Type: blogs
The one thing you need to do before IVF
A lot of IVF patients ask me what they need to do in order to prepare for an IVF cycle.Most of this is fairly common sense stuff , which they already know. They should be taking supplements , like folic acid. They should be fit, in good health, with the right BMI. They should stop smoking, and stop drinking, and you don't really need a doctor to tell you this !What I do tell them is I only want one thing from them - to come with lots of smiles - optimism and positivity always help !The best way to acquire this is to have realistic expectations of IVF, so you understand what is in your hands; what's in the doctor's han...
Source: Dr.Malpani's Blog - March 28, 2019 Category: Reproduction Medicine Source Type: blogs
The IVF Checklist
IVF can seem to be a demanding and complex treatment, which is why it helps if you are well organised !1. Make sure you have completed all your testsWife□ Ovarian reserve testing ( AMH, prolactin, TSH, antral follicle count)□ Infectious disease screen: HIV, Hepatitis, RPR , Rubella□ Vaginal ultrasound scanHusband□ Semen analysisInfectious disease screen: HIV, Hepatitis, RPR/VDRLPlease note how short this list is !Don't waste your money on useless and unnecessary tests such as sperm DNA fragmentation, TB testing, ERA, genetic testing or hysteroscopy !2. Make sure you know how much you have to p...
Source: Dr.Malpani's Blog - January 1, 2019 Category: Reproduction Medicine Source Type: blogs
Natural Answers for Depression
If you experience depression, you will typically be prescribed an antidepressant, an SSRI or other agent, and have to endure the common side-effects such as weight gain, aggression, anxiety, suicidal thoughts, and erectile dysfunction. If you consult a psychologist or counselor, the underlying psychological underpinnings (if any) are explored, strategies devised to cope. But there will almost never be talk about your diet, nutritional deficiencies that amplify dark moods, or the microbiome.
Yet there are very powerful strategies available that have potential to substantially lift mood. Such solutions won’t, of course...
Source: Wheat Belly Blog - December 10, 2018 Category: Cardiology Authors: Dr. Davis Tags: News & Updates anxiety bowel flora Depression Gliadin gluten-free grain-free grains Inflammation mood wheat belly Source Type: blogs
What's new in midwifery - 24th October 2018
Some recent things you might want to know about.Folic acidDepartment of Health and Social CareGovernment to consult over plans for mandatory fortification of food with folic acid, to prevent foetal abnormalitiesReportsAll Party Parliamentary Group for Children who need Palliative CareEnd of life care: strengthening choiceAbout all ages of young people, including babies.Children ’s CommissionerA crying shame: a report by the Office of the Children ’s Commissioner into vulnerable babies in EnglandStatisticsSex ratios at birth in Great Britain 2012-2016 NewsConcerns about the promotion of a cardboard baby box as a pl...
Source: Browsing - October 24, 2018 Category: Databases & Libraries Tags: midwifery Source Type: blogs
No Scientific Proof That Multivitamins Promote Heart Health
https://www.medscape.com/viewarticle/899130No Scientific Proof That Multivitamins Promote Heart HealthTaking multivitamin/mineral (MVM) supplements does not prevent myocardial infarction, stroke, or death from a cardiovascular cause, according to a comprehensive meta-analytic review of relevant research." The take-home message is simple: there is no scientific evidence that MVM supplements promote cardiovascular health. We hope that our paper helps to settle the controversy on MVM use for CVD prevention, " lead author Joonseok Kim, MD, University of Alabama at Birmingham, toldtheheart.org | Medscape Cardiology.The study wa...
Source: Dr Portnay - July 25, 2018 Category: Cardiology Authors: Dr Portnay Source Type: blogs
How doctors take advantage of IVF patient's ignorance
A patient sent me this email.-----Original Message-----From:To: Aniruddha MalpaniSubject: Re: Two ivf cycles failedSir,Can U pls suggest ivf success supplements?Next month I m going for third cycleCan I use mothers Horlicks?How to get good eggs and embryos?Any diet chart before, during and after embryo transfer?Sir, pls kindly suggest meLifelong I will be really thankful to youNow I m taking1. apcod sachets2. Metformin3. Normoz4. Ultra CoQ105. Folic acidMy previous ivf failure reasons are poor quality eggs and embryos, implantation failure and may be unexplained infertility reason Actually, the most likely reason for ...
Source: Dr.Malpani's Blog - July 21, 2018 Category: Reproduction Medicine Source Type: blogs
