The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
The role of metabolism in cardiac development
Curr Top Dev Biol. 2024;156:201-243. doi: 10.1016/bs.ctdb.2024.01.005. Epub 2024 Feb 9.ABSTRACTMetabolism is the fundamental process that sustains life. The heart, in particular, is an organ of high energy demand, and its energy substrates have been studied for more than a century. In recent years, there has been a growing interest in understanding the role of metabolism in the early differentiation of pluripotent stem cells and in cancer research. Studies have revealed that metabolic intermediates from glycolysis and the tricarboxylic acid cycle act as co-factors for intracellular signal transduction, playing crucial role...
Source: Current Topics in Developmental Biology - March 31, 2024 Category: Biology Authors: Haruko Nakano Atsushi Nakano Source Type: research
Molecules, Vol. 29, Pages 1564: Redox-Responsive Gold Nanoparticles Coated with Hyaluronic Acid and Folic Acid for Application in Targeting Anticancer Therapy
Kwon Taek Lim
Metxate (MTX) has poor water solubility and low bioavailability, and cancer cells can become resistant to it, which limits its safe delivery to tumor sites and reduces its clinical efficacy. Herein, we developed novel redox-responsive hybrid nanoparticles (NPs) from hyaluronic acid (HA) and 3-mercaptopropionic acid (MPA)-coated gold NPs (gold@MPA NPs), which were further conjugated with folic acid (FA). The design of FA-HA-ss-gold NPs aimed at enhancing cellular uptake specifically in cancer cells using an active FA/HA dual targeting strategy for enhanced tumor eradication. MTX was successfully encapsulat...
Source: Molecules - March 31, 2024 Category: Chemistry Authors: Raissa Munderere Muhammad Gulfam Israr Ali Seon-Hwa Kim Trung Thang Vu Sang-Hyug Park Kwon Taek Lim Tags: Article Source Type: research
Are migrants during the periconception period less likely to be supplementing with folic acid: An Australian cohort study
CONCLUSION: A significant proportion of the population did not report FA supplementation before or during early pregnancy. To increase uptake of FA supplementation, clinicians and public health messaging should target at-risk groups.PMID:38554606 | DOI:10.1016/j.midw.2024.103984 (Source: Midwifery)
Source: Midwifery - March 30, 2024 Category: Midwifery Authors: Hei Yee Tang James Elhindi Caron Blumenthal Dharmintra Pasupathy Sarah J Melov Source Type: research
Are migrants during the periconception period less likely to be supplementing with folic acid: An Australian cohort study
CONCLUSION: A significant proportion of the population did not report FA supplementation before or during early pregnancy. To increase uptake of FA supplementation, clinicians and public health messaging should target at-risk groups.PMID:38554606 | DOI:10.1016/j.midw.2024.103984 (Source: Midwifery)
Source: Midwifery - March 30, 2024 Category: Midwifery Authors: Hei Yee Tang James Elhindi Caron Blumenthal Dharmintra Pasupathy Sarah J Melov Source Type: research
