Vitamin B12 deficiency in diabetic patients treated with metformin: A cross-sectional study
This study set out to evaluate the rate of vitamin B12 deficiency in Vietnamese patients with type 2 diabetes who were t reated with metformin and to investigate factors associated with vitamin B12 deficiency. This is a cross-sectional study that was conducted in Vinmec Central Park Hospital from February to June 2023. The clinical and paraclinical characteristics of the participants were recorded, and the levels of v itamin B12 and folate were measured. The rate of vitamin B12 deficiency in patients treated with metformin was found to be 18.6%. Further, the duration of diabetes, duration of metformin use, metformin dose, ...
Source: PLoS One - April 25, 2024 Category: Biomedical Science Authors: Dat Tan Huynh Source Type: research
Inappropriate laboratory test utilization in outpatient tertiary care: Implications for value-based healthcare
CONCLUSION: The study identified significantly high rates of inadequate repetitions of frequently requested laboratory tests. Urgent action is therefore crucial to overcoming such an issue.PMID:38657991 | DOI:10.15537/smj.2024.45.4.20230512 (Source: Saudi Medical Journal)
Source: Saudi Medical Journal - April 24, 2024 Category: Middle East Health Authors: Nouf F Almasoud Mohammed A Aldosari Ahmed S Mahmoud Yaser A Alendijani Abdullah H Alkhenizan Source Type: research
Evaluation of anti-seizure medications and their serum concentration with regard to cardiovascular risk parameters: A cross-sectional study
CONCLUSION: In our study, the majority of patients were children and adolescents. Regular monitoring of drug serum concentrations and metabolic parameters may be useful to select the safest drug in terms of cardiovascular disease risk. Randomized controlled trials on the long-term effects of anti-seizure treatment are needed.PMID:38657483 | DOI:10.1016/j.yebeh.2024.109802 (Source: Epilepsy and Behaviour)
Source: Epilepsy and Behaviour - April 24, 2024 Category: Neurology Authors: Merve Becit-Kizilkaya Seyma Oncu Halit Bugra Koca Dilek Cavusoglu Source Type: research
Serum vitamins and homocysteine levels in autoimmune liver disease: A systematic review and meta ‐analysis
ConclusionMost vitamins are deficient in AILD, so appropriate vitamin supplementation should be necessary. Further studies with larger sample sizes are needed to validate these findings. (Source: Immunity, Inflammation and Disease)
Source: Immunity, Inflammation and Disease - April 23, 2024 Category: Allergy & Immunology Authors: Jiahuan Li,
Shan Tian,
Bai Ci,
Yuwen Xi,
Xiaoling Deng Tags: REVIEW ARTICLE Source Type: research
Association of IL-1 β 542 T & gt;A gene polymorphism with Recurrent Aphthous Stomatitis in Erbil City population
Cell Mol Biol (Noisy-le-grand). 2024 Mar 31;70(3):7-12. doi: 10.14715/cmb/2024.70.3.2.ABSTRACTRecurrent Aphthous stomatitis (RAS) is common oral mucosal condition. The pathophysiology of RAS is affected by a variety of variables, including microbial, genetic, immunological and local and systemic diseases. Interleukin IL-1β, a cytokine that promotes inflammation, has been found in high concentrations in the circulation of RAS. The goal of current investigation was to determine whether RAS is connected with polymorphisms of the IL-1β 542 T>A gene. A total of 60 RAS patients and 30 controls were included in the study. Bi...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Asma Qasim Rahman Reiadh Kamal Al-Kamali Source Type: research
Association of IL-1 β 542 T & gt;A gene polymorphism with Recurrent Aphthous Stomatitis in Erbil City population
Cell Mol Biol (Noisy-le-grand). 2024 Mar 31;70(3):7-12. doi: 10.14715/cmb/2024.70.3.2.ABSTRACTRecurrent Aphthous stomatitis (RAS) is common oral mucosal condition. The pathophysiology of RAS is affected by a variety of variables, including microbial, genetic, immunological and local and systemic diseases. Interleukin IL-1β, a cytokine that promotes inflammation, has been found in high concentrations in the circulation of RAS. The goal of current investigation was to determine whether RAS is connected with polymorphisms of the IL-1β 542 T>A gene. A total of 60 RAS patients and 30 controls were included in the study. Bi...
Source: Mol Biol Cell - April 23, 2024 Category: Molecular Biology Authors: Asma Qasim Rahman Reiadh Kamal Al-Kamali Source Type: research
Association of IL-1 β 542 T & gt;A gene polymorphism with Recurrent Aphthous Stomatitis in Erbil City population
Cell Mol Biol (Noisy-le-grand). 2024 Mar 31;70(3):7-12. doi: 10.14715/cmb/2024.70.3.2.ABSTRACTRecurrent Aphthous stomatitis (RAS) is common oral mucosal condition. The pathophysiology of RAS is affected by a variety of variables, including microbial, genetic, immunological and local and systemic diseases. Interleukin IL-1β, a cytokine that promotes inflammation, has been found in high concentrations in the circulation of RAS. The goal of current investigation was to determine whether RAS is connected with polymorphisms of the IL-1β 542 T>A gene. A total of 60 RAS patients and 30 controls were included in the study. Bi...
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Asma Qasim Rahman Reiadh Kamal Al-Kamali Source Type: research
Use of complementary and alternative medicine in vitiligo: a cross-sectional survey
AbstractVitiligo is characterized by skin depigmentation, which can lead to profound psychological effects and decreased quality of life, especially for those with skin of color. Individuals with vitiligo may utilize complementary and alternative medicine (CAM) due to limited treatment options with varying efficacy.An anonymous, multiple-choice, cross-sectional questionnaire was distributed to participants with vitiligo in the United States through online forums. Data on disease characteristics, use of prescription medications, use of topical therapies, supplements, and diets, and perceptions of CAM were collected.In total...
Source: Archives of Dermatological Research - April 23, 2024 Category: Dermatology Source Type: research
Interactions between folate metabolism-related nutrients and polymorphisms on colorectal cancer risk: a case-control study in the Basque country
AbstractFolate-mediated one-carbon metabolism (FOCM) plays an important role in colorectal carcinogenesis. Previous studies have assessed the role of folate-mediated one-carbon metabolism (FOCM)-related gene-diet interaction in the aetiology of colorectal cancer (CRC), however, the results remained inconclusive. Thus, this study aimed to investigate dietary factors and genetic variants related to FOCM, as well as potential nutrient-gene and nutrient-lifestyle interactions, on CRC risk. This observational study included 229 patients diagnosed with CRC and 229 age- and sex-matched subjects as controls from a population-based...
Source: European Journal of Nutrition - April 23, 2024 Category: Nutrition Source Type: research
Use of complementary and alternative medicine in vitiligo: a cross-sectional survey
AbstractVitiligo is characterized by skin depigmentation, which can lead to profound psychological effects and decreased quality of life, especially for those with skin of color. Individuals with vitiligo may utilize complementary and alternative medicine (CAM) due to limited treatment options with varying efficacy.An anonymous, multiple-choice, cross-sectional questionnaire was distributed to participants with vitiligo in the United States through online forums. Data on disease characteristics, use of prescription medications, use of topical therapies, supplements, and diets, and perceptions of CAM were collected.In total...
Source: Archives of Dermatological Research - April 23, 2024 Category: Dermatology Source Type: research
The Effect of Whey Protein Supplements on Acne Vulgaris among Male Adolescents and Young Adults: A Case-Control Study from North of Jordan
CONCLUSION: This case-control study provides evidence of a positive association between whey protein consumption and acne risk.PMID:38633058 | PMC:PMC11022506 | DOI:10.1155/2024/2158229 (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - April 18, 2024 Category: Dermatology Authors: Jihan Muhaidat Almutazballlah Qablan Faris Gharaibeh Ghaith H Albataineh Nour Abdo Diala Alshiyab Firas Al-Qarqaz Source Type: research
Serum Folate and Vitamin B12 Modify the Associations of N6AMT1 Genetic Variants with Gestational Diabetes Mellitus: A Cross-Sectional Study in Chinese Pregnant Women
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 17, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Characteristics of the Digestive Tract of Dogs and Cats
Adv Exp Med Biol. 2024;1446:15-38. doi: 10.1007/978-3-031-54192-6_2.ABSTRACTAs for other mammals, the digestive system of dogs (facultative carnivores) and cats (obligate carnivores) includes the mouth, teeth, tongue, pharynx, esophagus, stomach, small intestine, large intestine, and accessory digestive organs (salivary glands, pancreas, liver, and gallbladder). These carnivores have a relatively shorter digestive tract but longer canine teeth, a tighter digitation of molars, and a greater stomach volume than omnivorous mammals such as humans and pigs. Both dogs and cats have no detectable or a very low activity of salivar...
Source: Advances in Experimental Medicine and Biology - April 16, 2024 Category: Research Authors: Wenliang He Erin D Connolly Guoyao Wu Source Type: research
