GSE225105 Vitamin B12 alleviates myocardial ischemia/reperfusion injury
Contributors : Zhe Cheng ; Q YuSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo examine the protective effect of B12 on myocardial ischemia/reperfusion injury and figure out the mechanism of B12. (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - January 1, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

The role of dietitian follow-ups on nutritional outcomes post-bariatric surgery
CONCLUSION: Our study suggests that three or more RD visits during the first 12 months after bariatric surgery are associated with improved outcomes, including significant percent total body weight loss and lower rates of micronutrient deficiencies.PMID:38158312 | DOI:10.1016/j.soard.2023.10.017 (Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery)
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - December 29, 2023 Category: Surgery Authors: Mariam Hassan Juan S Barajas-Gamboa Oshin Kanwar Terrence Lee-St John Diana Tannous Ricard Corcelles John Rodriguez Matthew Kroh Source Type: research

Methotrexate-induced subacute myelopathy: a serious but treatable complication
J Clin Exp Hematop. 2023;63(4):251-256. doi: 10.3960/jslrt.23041.ABSTRACTSubacute myelopathy is a rare but serious complication of methotrexate (MTX) that may cause paraplegia. Although its underlying mechanisms have not been fully elucidated, homocysteine is thought to play a role in the pathogenesis of this adverse effect. Herein, we report the case of a 34-years old female patient with diffuse large B-cell lymphoma who developed progressive paraplegia accompanied by dysfunctional bladder and bowel movements after treatment with a modified CODOX-M/IVAC regimen, including high-dose intravenous MTX and intrathecal (IT-) MT...
Source: Journal of Clinical and Experimental Hematopathology : JCEH - December 26, 2023 Category: Hematology Authors: Takashi Miyoshi Tadakazu Kondo Momoko Nishikori Toshio Kitawaki Katsuya Kobayashi Masakazu Fujimoto Noriyoshi Yoshinaga Satoshi Oka Kohsuke Asagoe Shinsaku Imashuku Akifumi Takaori-Kondo Source Type: research

Methotrexate-induced subacute myelopathy: a serious but treatable complication
J Clin Exp Hematop. 2023;63(4):251-256. doi: 10.3960/jslrt.23041.ABSTRACTSubacute myelopathy is a rare but serious complication of methotrexate (MTX) that may cause paraplegia. Although its underlying mechanisms have not been fully elucidated, homocysteine is thought to play a role in the pathogenesis of this adverse effect. Herein, we report the case of a 34-years old female patient with diffuse large B-cell lymphoma who developed progressive paraplegia accompanied by dysfunctional bladder and bowel movements after treatment with a modified CODOX-M/IVAC regimen, including high-dose intravenous MTX and intrathecal (IT-) MT...
Source: Journal of Clinical and Experimental Hematopathology : JCEH - December 26, 2023 Category: Hematology Authors: Takashi Miyoshi Tadakazu Kondo Momoko Nishikori Toshio Kitawaki Katsuya Kobayashi Masakazu Fujimoto Noriyoshi Yoshinaga Satoshi Oka Kohsuke Asagoe Shinsaku Imashuku Akifumi Takaori-Kondo Source Type: research

GSE232691 Impact of the vitamin B12 on the transcriptional regulation of the Mycobacterium tuberculosis Complex
Contributors : Jes ús Gonzalo-Asensio ; Elena Campos-PardosSeries Type : Expression profiling by high throughput sequencingOrganism : Mycobacterium tuberculosis ; Mycobacterium tuberculosis variant bovisThe transcriptome in response to vitamin B12 was interrogated in three M. tuberculosis Complex species: M. tuberculosis H37Rv, M. tuberculosis GC1237, and M. bovis AF2122/97. Examination of the core B12 transcriptome resulted in a robust differential regulation of 7 genes in the three species analysed (Source: GEO: Gene Expression Omnibus)
Source: GEO: Gene Expression Omnibus - December 22, 2023 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mycobacterium tuberculosis Mycobacterium tuberculosis variant bovis Source Type: research

A case of functional vitamin B12 deficiency after recreational nitrous oxide use
Biochem Med (Zagreb). 2024 Feb 15;34(1):010801. doi: 10.11613/BM.2024.010801. Epub 2023 Dec 15.ABSTRACTThe recreational use of nitrous oxide as laughing gas becomes a real public health issue among adolescents and young adults. Chronic use is deleterious and can lead to severe neurological disorders. Nitrous oxide inactivates vitamin B12, and the functional defect of vitamin B12 plays a major role in the pathogenesis of nitrous oxide-related neurological disorders. Here we report the case of a 22-year-old woman who came to the hospital after an unexplained loss of consciousness. She exhibited typical features of vitamin B1...
Source: Biochemia Medica - December 21, 2023 Category: Biochemistry Authors: Damien Leleu Damien Denimal Source Type: research