Microalgae/cyanobacteria: the potential green future of vitamin B12 production
(Source: Critical Reviews in Food Science and Nutrition)
Source: Critical Reviews in Food Science and Nutrition - April 6, 2024 Category: Nutrition Authors: Durdakova, Michaela Kolackova, Martina Janova, Anna Krystofova, Olga Adam, Vojtech Huska, Dalibor Source Type: research

Clinico-Etiopathogenesis of Vitamin B12, Folic Acid and Iron Deficiency in Severe Acute Malnutrition Children: A Tertiary Care Hospital Experience from Central India
In this study, haematological indices are recommended for predicting severity of anemia, and hematopoietic changes are described, in order to improve anticipatory care and outcome in children with SAM.PMID:38577146 | PMC:PMC10987456 | DOI:10.1007/s12291-022-01100-5 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Priyanka Shukla Sanjay Kumar Pandey Jyoti Singh Naresh Bajaj Gaurav Tripathi Sudhakar Dwivedi Source Type: research

Clinico-Etiopathogenesis of Vitamin B12, Folic Acid and Iron Deficiency in Severe Acute Malnutrition Children: A Tertiary Care Hospital Experience from Central India
In this study, haematological indices are recommended for predicting severity of anemia, and hematopoietic changes are described, in order to improve anticipatory care and outcome in children with SAM.PMID:38577146 | PMC:PMC10987456 | DOI:10.1007/s12291-022-01100-5 (Source: Clinical Biochemistry)
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Priyanka Shukla Sanjay Kumar Pandey Jyoti Singh Naresh Bajaj Gaurav Tripathi Sudhakar Dwivedi Source Type: research

Cobalamins function as allosteric activators of an Angelman syndrome-associated UBE3A/E6AP variant
Chembiochem. 2024 Apr 4:e202400184. doi: 10.1002/cbic.202400184. Online ahead of print.ABSTRACTGenetic aberrations of the maternal UBE3A allele, which encodes the E3 ubiquitin ligase E6AP, are the cause of Angelman syndrome (AS), an imprinting disorder. In most cases, the maternal UBE3A allele is not expressed. Yet, approximately 10 percent of AS individuals harbor distinct point mutations in the maternal allele resulting in the expression of full-length E6AP variants that frequently display compromised ligase activity. In a high-throughput screen, we identified cyanocobalamin, a vitamin B12-derivative, and several alloxaz...
Source: Chembiochem - April 4, 2024 Category: Biochemistry Authors: Franziska M üller Jasmin Jansen Fabian Offensperger Daniela Eichbichler Florian Stengel Martin Scheffner Source Type: research

The Effects of an Eight-Week Swimming Program on Body Composition and Assessment of Dietary Intake in Post-COVID-19 Patients
J Nutr Metab. 2024 Mar 27;2024:3037784. doi: 10.1155/2024/3037784. eCollection 2024.ABSTRACTCOVID-19 infection and its consequences (long-term COVID-19 syndrome) have implications for weight loss, body composition, and diet quality. In the context of the "PostCovSwim" project, which is part of a broader international study, the impact of an eight-week swimming program on post-COVID-19 patients' nutritional status (i.e., body composition and dietary intake) was evaluated. Body composition and dietary intake were assessed by medically approved and calibrated bioelectrical impedance (Tanita 780 S MA) and food frequency questi...
Source: Journal of Nutrition and Metabolism - April 4, 2024 Category: Nutrition Authors: Bostjan Jak še Barbara Gili ć Marko Đurović Dorica Šajber Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: Pain Physician - April 4, 2024 Category: Anesthesiology Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

Cobalamins function as allosteric activators of an Angelman syndrome-associated UBE3A/E6AP variant
Chembiochem. 2024 Apr 4:e202400184. doi: 10.1002/cbic.202400184. Online ahead of print.ABSTRACTGenetic aberrations of the maternal UBE3A allele, which encodes the E3 ubiquitin ligase E6AP, are the cause of Angelman syndrome (AS), an imprinting disorder. In most cases, the maternal UBE3A allele is not expressed. Yet, approximately 10 percent of AS individuals harbor distinct point mutations in the maternal allele resulting in the expression of full-length E6AP variants that frequently display compromised ligase activity. In a high-throughput screen, we identified cyanocobalamin, a vitamin B12-derivative, and several alloxaz...
Source: Chembiochem - April 4, 2024 Category: Biochemistry Authors: Franziska M üller Jasmin Jansen Fabian Offensperger Daniela Eichbichler Florian Stengel Martin Scheffner Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

The Effects of an Eight-Week Swimming Program on Body Composition and Assessment of Dietary Intake in Post-COVID-19 Patients
J Nutr Metab. 2024 Mar 27;2024:3037784. doi: 10.1155/2024/3037784. eCollection 2024.ABSTRACTCOVID-19 infection and its consequences (long-term COVID-19 syndrome) have implications for weight loss, body composition, and diet quality. In the context of the "PostCovSwim" project, which is part of a broader international study, the impact of an eight-week swimming program on post-COVID-19 patients' nutritional status (i.e., body composition and dietary intake) was evaluated. Body composition and dietary intake were assessed by medically approved and calibrated bioelectrical impedance (Tanita 780 S MA) and food frequency questi...
Source: Journal of Nutrition and Metabolism - April 4, 2024 Category: Nutrition Authors: Bostjan Jak še Barbara Gili ć Marko Đurović Dorica Šajber Source Type: research

Cobalamins function as allosteric activators of an Angelman syndrome-associated UBE3A/E6AP variant
Chembiochem. 2024 Apr 4:e202400184. doi: 10.1002/cbic.202400184. Online ahead of print.ABSTRACTGenetic aberrations of the maternal UBE3A allele, which encodes the E3 ubiquitin ligase E6AP, are the cause of Angelman syndrome (AS), an imprinting disorder. In most cases, the maternal UBE3A allele is not expressed. Yet, approximately 10 percent of AS individuals harbor distinct point mutations in the maternal allele resulting in the expression of full-length E6AP variants that frequently display compromised ligase activity. In a high-throughput screen, we identified cyanocobalamin, a vitamin B12-derivative, and several alloxaz...
Source: Chembiochem - April 4, 2024 Category: Biochemistry Authors: Franziska M üller Jasmin Jansen Fabian Offensperger Daniela Eichbichler Florian Stengel Martin Scheffner Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research

The Effects of an Eight-Week Swimming Program on Body Composition and Assessment of Dietary Intake in Post-COVID-19 Patients
J Nutr Metab. 2024 Mar 27;2024:3037784. doi: 10.1155/2024/3037784. eCollection 2024.ABSTRACTCOVID-19 infection and its consequences (long-term COVID-19 syndrome) have implications for weight loss, body composition, and diet quality. In the context of the "PostCovSwim" project, which is part of a broader international study, the impact of an eight-week swimming program on post-COVID-19 patients' nutritional status (i.e., body composition and dietary intake) was evaluated. Body composition and dietary intake were assessed by medically approved and calibrated bioelectrical impedance (Tanita 780 S MA) and food frequency questi...
Source: Journal of Nutrition and Metabolism - April 4, 2024 Category: Nutrition Authors: Bostjan Jak še Barbara Gili ć Marko Đurović Dorica Šajber Source Type: research

Cobalamins function as allosteric activators of an Angelman syndrome-associated UBE3A/E6AP variant
Chembiochem. 2024 Apr 4:e202400184. doi: 10.1002/cbic.202400184. Online ahead of print.ABSTRACTGenetic aberrations of the maternal UBE3A allele, which encodes the E3 ubiquitin ligase E6AP, are the cause of Angelman syndrome (AS), an imprinting disorder. In most cases, the maternal UBE3A allele is not expressed. Yet, approximately 10 percent of AS individuals harbor distinct point mutations in the maternal allele resulting in the expression of full-length E6AP variants that frequently display compromised ligase activity. In a high-throughput screen, we identified cyanocobalamin, a vitamin B12-derivative, and several alloxaz...
Source: Chembiochem - April 4, 2024 Category: Biochemistry Authors: Franziska M üller Jasmin Jansen Fabian Offensperger Daniela Eichbichler Florian Stengel Martin Scheffner Source Type: research

Diabetic Peripheral Neuropathy: Prevention and Treatment
Am Fam Physician. 2024 Mar;109(3):226-232.ABSTRACTDiabetic peripheral neuropathy occurs in up to 50% of patients with diabetes mellitus and increases the risk of diabetic foot ulcers and infections. Consistent screening and clear communication are essential to decrease disparities in assessment of neuropathic symptoms and diagnosis. Physicians should address underlying risk factors such as poor glycemic control, vitamin B12 deficiency, elevated blood pressure, and obesity to reduce the likelihood of developing neuropathy. First-line drug therapy for painful diabetic peripheral neuropathy includes duloxetine, gabapentin, am...
Source: American Family Physician - April 4, 2024 Category: Primary Care Authors: Scott Bragg Sarah Tucker Marrison Sean Haley Source Type: research