Prevalence of Dermatophytosis and Antifungal Activity of Ethanolic Crude Leaf Extract of Tetradenia riparia against Dermatophytes Isolated from Patients Attending Kampala International University Teaching Hospital, Uganda.
Authors: Kakande T, Batunge Y, Eilu E, Shabohurira A, Abimana J, Akinola SA, Muhwezi R, Sunusi Adam A, Kemuma Onkoba S, Almustapha Aliero A, Atuheire C, Kato CD, Ntulume I Abstract Dermatophyte infections are a global health problem but neglected in Uganda. This work aimed at determining prevalence of dermatophytosis and antifungal activity of ethanolic crude leaf extract of Tetradenia riparia against dermatophytes isolated from patients attending Kampala International University Teaching Hospital (KIU-TH), Uganda. A total of 100 samples of skin and nail scrapings were collected and processed using standard microsc...
Source: Dermatology Research and Practice - August 6, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Effectiveness of the Electromagnetic Shock Wave Therapy in the Treatment of Cellulite.
Authors: Modena DAO, Nogueira da Silva C, Delinocente TCP, Bianca de Araújo T, de Carvalho TM, Grecco C, Moreira RG, Campos G, de Souza JR, Michelini Guidi R Abstract In the past centuries, the human body was undervalued; nowadays, however, it is overvalued, and thus the manifestation of the dissatisfactions regarding the body has been increasing. Most of the time, these dissatisfactions are related to cellulite, which is most common in women. Its treatment is one of the challenges which encourage the development of new therapeutic modalities, among them the shockwave therapy. Objective. To evaluate the effi...
Source: Dermatology Research and Practice - July 20, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Position Statement on Secukinumab in the Management of Plaque Psoriasis: The Malaysian Perspective.
Authors: Johar A, Thevarajah S, Heng A, Chan LC, Ch'ng CC, Mohd Safdar NA, Muniandy P, Taib T, Tan WC, Tey KE Abstract Psoriasis is a chronic inflammatory skin disease affecting nearly 10% of dermatologic patients in Malaysia. Treatment options include topical agents and phototherapy as well as nonbiologic and biologic systemic therapy. Mild psoriasis can often be managed with topical agents. However, managing moderate to severe psoriasis is more challenging and may require systemic treatment with nonbiologics or biologics. Despite the availability of several biologics, there are many unmet clinical needs, which ma...
Source: Dermatology Research and Practice - June 20, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

The Clinical Effect of Oral Vitamin D2 Supplementation on Psoriasis: A Double-Blind, Randomized, Placebo-Controlled Study.
Conclusion: Oral vitamin D2 supplementation in patients with psoriasis increased the serum vitamin D level and significantly improved the treatment outcome without increasing adverse events. Trial Registration: This trial is registered with Thai Clinical Trials Registry TCTR20180613001. PMID: 31139214 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - May 31, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Radiotherapy for Melanoma: More than DNA Damage.
Authors: Rogers SJ, Puric E, Eberle B, Datta NR, Bodis SB Abstract Despite its reputation as a radioresistant tumour, there is evidence to support a role for radiotherapy in patients with melanoma and we summarise current clinical practice. Melanoma is a highly immunogenic tumour and in this era of immunotherapy, there is renewed interest in the potential of irradiation, not only as an adjuvant and palliative treatment, but also as an immune stimulant. It has long been known that radiation causes not only DNA strand breaks, apoptosis, and necrosis, but also immunogenic modulation and cell death through the inductio...
Source: Dermatology Research and Practice - May 11, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Gender Differences in Depression, Coping, Stigma, and Quality of Life in Patients of Vitiligo.
Authors: Sawant NS, Vanjari NA, Khopkar U Abstract Though vitiligo is one of the psychodermatological disorders which do not cause direct physical impairment, it is cosmetically disfiguring leading to serious psychological problems in daily life. We undertook this research to study patients of vitiligo the prevalence of depression, coping, stigma, and quality of life and comparison of the same in both genders. Patients diagnosed clinically as having vitiligo by consultant dermatologist were enrolled after informed consent and ethics approval. 156 patients were screened, of which 100 satisfying criteria were taken u...
Source: Dermatology Research and Practice - May 10, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Epidemiologic Trends of Viral Skin Infections in Egypt: A Cross-Sectional Hospital-Based Study.
The objective of this study was to determine the epidemiologic features of VSIs in patients attending a dermatology clinic in Egypt from June 2010 to May 2011. Patient's residence, occupation, housing data, and family history of similar conditions were recorded. Categorical data were recorded as frequencies and percentages and were compared by Chi square test. P value
Source: Dermatology Research and Practice - May 1, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Impact of Allergic Contact Dermatitis on the Quality of Life and Work Productivity.
Authors: Kalboussi H, Kacem I, Aroui H, El Maalel O, Maoua M, Brahem A, El Guedri S, Chatti S, Ghariani N, Mrizak N Abstract Background: Allergic contact dermatitis (ACD) is a common chronic skin disease that generates considerable public-health and socioeconomic costs. This disease affects the quality of life and the occupational activity of patients. Aims: To assess the quality of life (QOL) of patients with ACD and study the impact of this disease on their work productivity. Methods: This is a cross-sectional study carried out from January 2012 to December 2014. All patients diagnosed with ACD in the Der...
Source: Dermatology Research and Practice - April 4, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Ocular and Mucocutaneous Sequelae among Survivors of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in Togo.
Conclusion: Ocular and mucocutaneous sequelae are common in SJS/TEN survivors. Exposure to sulfadoxine and severity of acute ocular involvement are risk factors of ocular sequelae. PMID: 30838038 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - March 8, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Pattern of Dermatological Disease Encountered in a Hematology Ward: A Retrospective Analysis of Dermatology Consultation in a Hematology Ward in a Tertiary Care Center in Saudi Arabia.
Conclusion. Various dermatological disorders and cutaneous manifestations are observed in hematology inpatients with morbilliform drug eruption and graft versus host disease being the most common. PMID: 30733801 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - February 9, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Pentavalent Antimonials Combined with Other Therapeutic Alternatives for the Treatment of Cutaneous and Mucocutaneous Leishmaniasis: A Systematic Review.
Authors: Berbert TRN, de Mello TFP, Wolf Nassif P, Mota CA, Silveira AV, Duarte GC, Demarchi IG, Aristides SMA, Lonardoni MVC, Vieira Teixeira JJ, Silveira TGV Abstract The first choice drugs for the treatment of cutaneous and mucocutaneous leishmaniasis are pentavalent antimonials, sodium stibogluconate, or meglumine antimoniate. However, the treatment with these drugs is expensive, can cause serious adverse effects, and is not always effective. The combination of two drugs by different routes or the combination of an alternative therapy with systemic therapy can increase the efficacy and decrease the collateral e...
Source: Dermatology Research and Practice - January 26, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Effectiveness and Safety of Contrast Cryolipolysis for Subcutaneous-Fat Reduction.
Authors: Savacini MB, Bueno DT, Molina ACS, Lopes ACA, Silva CN, Moreira RG, Almeida S, Guidi RM, Sant'Ana E, Liebano RE Abstract Cryolipolysis is the noninvasive treatment of localized fat through cold-induced panniculitis. The purpose of the present study was to evaluate the safety and efficacy of contrast cryolipolysis for subcutaneous-fat reduction. Contrast cryolipolysis mixes the principles of conventional cryolipolysis and periods of heating in accordance with the contrast lipocryolysis process. Twenty-one subjects aged 34 ± 9 years were treated with contrast cryolipolysis in the regions of abdomen an...
Source: Dermatology Research and Practice - January 13, 2019 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Comparing the Efficacy of Triamcinolone Acetonide Iontophoresis versus Topical Calcipotriol/Betamethasone Dipropionate in Treating Nail Psoriasis: A Bilateral Controlled Clinical Trial.
Conclusion: Monthly TI has an equal efficacy compared to daily topical calcipotriol/betamethasone dipropionate. It can be used as a safe, easy, and compliant treatment for nail psoriasis. This study is registered under IRCT2017050233778N1. PMID: 30584420 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - December 27, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

A Real-Life Based Evaluation of the Effectiveness of Antibacterial Fabrics in Treating Atopic Dermatitis.
Conclusion: Considerable differences in the antibacterial effectiveness of conventional AD clothes were revealed. Under practical (dry) wear conditions, garments were unable to modify skin colonization with S. aureus, although effectiveness can be triggered by wetting the garments. Remnants of moisturising cream remain on the fibres after laundry. PMID: 30581460 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - December 26, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Investigation of Interleukin-27 in the Sera of Nonmelanoma Skin Cancer Patients.
In this study we observed that IL-27 serum levels were significantly higher in NMSC patients in comparison to healthy individuals (0.0134 versus 0.0008 ng/ml; P
Source: Dermatology Research and Practice - December 26, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Dermatophytosis: Prevalence of Dermatophytes and Non-Dermatophyte Fungi from Patients Attending Arsho Advanced Medical Laboratory, Addis Ababa, Ethiopia.
Conclusions: Failure to detect or isolate fungal pathogens in a large number of clinical samples revealed the limitation of clinical diagnosis in differentiating dermatophytosis from other skin infections demonstrating that clinical diagnosis should be coupled with laboratory methods. Recovery of large number of non-dermatophyte fungi along with dermatophytes in our study showed that non-dermatophyte fungi are emerging as important causes of dermatophytosis, warranting the implementation of intensive epidemiological studies of dermatophytosis across the country. PMID: 30402089 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - November 9, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Confocal Microscopy Predicts the Risk of Recurrence and Malignant Transformation of Mucocutaneous Neurofibromas in NF-1: An Observational Study.
Authors: Giudice G, Favia G, Tempesta A, Limongelli L, Vestita M Abstract From 2005 to 2010, 20 consecutive patients with fully manifested neurofibromatosis type 1 (NF1) underwent elective neurofibroma resection at our institution (Departments of Plastic Surgery and of Odontostomatology). Specimens were photographed under optical microscope and confocal laser scanning microscopy (CLSM) with ultra-high accuracy of detail, including depth of field. Patients were followed up for a minimum of 4 years and up to a maximum of 12 years, postsurgery. While all nonrecurring lesions showed intense fluorescence, six of the sev...
Source: Dermatology Research and Practice - October 3, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Histomorphometrical Study on Regional Variation in Distribution of Sweat Glands in Buffalo Skin.
Authors: Debbarma D, Uppal V, Bansal N, Gupta A Abstract The study was conducted on skin of 24 buffaloes collected from slaughter house. The skin tissues were collected from dorsal, lateral, and ventral parts of head, neck, thorax, abdomen, and tail regions and fixed in 10% neutral buffered formalin. The tissues were processed for paraffin blocks preparation by acetone benzene schedule. The paraffin sections of 5-6 μm were cut with rotary microtome and stained with hematoxylin and eosin. The sweat glands in buffaloes were of saccular and simple coiled tubular type. Most of the sweat glands were associated...
Source: Dermatology Research and Practice - September 8, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Whole Genome Sequencing in an Acrodermatitis Enteropathica Family from the Middle East.
We report a family from Tabuk, Saudi Arabia, previously screened for Acrodermatitis Enteropathica (AE), in which two siblings presented with typical features of acral dermatitis and a pustular eruption but differing severity. Affected members of our family carry a rare genetic variant, p.Gly512Trp in the SLC39A4 gene which encodes a zinc transporter; disease is thought to result from zinc deficiency. Similar mutations have been reported previously; however, the variable severity within cases carrying the p.Gly512Trp variant and in AE overall led us to hypothesise that additional genetic modifiers may be contributing to the...
Source: Dermatology Research and Practice - September 5, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Autologous Fat Grafting in the Treatment of Facial Scleroderma.
In this study, we aimed to assess the safety and efficacy of autologous fat grafting in the face of patients with systemic sclerosis. We enrolled 16 SSc patients suffering from facial sclerosis and limited mouth opening capacity. Autologous fat injection ranging from 15 to 40 ml was administered per patient, based on their face morphology. The patients were evaluated at baseline and 3 months after fat injection. Evaluations included mouth opening capacity, mouth handicap in systemic sclerosis (MHISS), Rodnan skin sclerosis score, skin biophysical properties using a sensitive biometrologic device with the assessment of cuta...
Source: Dermatology Research and Practice - August 31, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Cutaneous Tuberculosis: Clinicopathologic Arrays and Diagnostic Challenges.
This article revises the current scenario of the disease's physiopathology and underscores clinicopathological challenges, due to multifaceted presentations of cutaneous tuberculosis, in the diagnosis. PMID: 30111996 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - August 18, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Experience with Treating Lentigo Maligna with Definitive Radiotherapy.
Authors: Fogarty GB, Hong A, Economides A, Guitera P Abstract Lentigo maligna (LM) is a form of melanoma in situ that occurs on exposed, sun-damaged skin; LM can progress to invasive melanoma. Conventional surgical treatment is the preferred management option as it is usually a one-treatment episode and generates a histopathology report that records completion of excision. Some patients may not be surgical candidates due to comorbidities, patient preference, impact on function, and cosmesis or they have failed surgery with a positive margin. Other therapies, including radiotherapy (RT) and topical medicines, may th...
Source: Dermatology Research and Practice - August 15, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Evaluation of Therapeutic Efficacy and Safety of Tranexamic Acid Local Infiltration in Combination with Topical 4% Hydroquinone Cream Compared to Topical 4% Hydroquinone Cream Alone in Patients with Melasma: A Split-Face Study.
This study was a prospective assessor- and analyst-blind, randomized split-face clinical trial which was performed on patients with bilateral malar epidermal melasma. A total of 55 patients were enrolled, and each side of their face was randomly allocated to either TA+HQ or HQ alone treatment. The MASI score was applied as an objective measurement to compare two treatment groups. The patient's satisfaction of melasma treatment was evaluated using a four-scale grading, as well. Results: The mean of MASI score in week 16 decreased in both groups significantly (p
Source: Dermatology Research and Practice - August 9, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Clinical Diagnostic Accuracy of Onychomycosis: A Multispecialty Comparison Study.
Authors: Li DG, Cohen JM, Mikailov A, Williams RF, Laga AC, Mostaghimi A Abstract Although onychomycosis can be diagnosed clinically, many guidelines still recommend pathologic confirmation of the diagnosis prior to initiation of systemic treatment. We retrospectively reviewed results from 541 toenail clippings (160 by dermatologists, 198 by podiatrists, and 183 by other provider types) sent to the Brigham and Women's Department of Dermatopathology between January 2000 and December 2013 for confirmatory periodic acid-Schiff (PAS) testing of clinically diagnosed onychomycosis. Of these, 93 (58.1%), 125 (63.1%), and ...
Source: Dermatology Research and Practice - August 4, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Efficacy and Safety of the Traditional Japanese Medicine Keigairengyoto in the Treatment of Acne Vulgaris.
In this study, we examined the effectiveness and safety of KRT in treating acne vulgaris. An open-label, randomized, parallel control group comparison was conducted with a conventional treatment group (adapalene and topical antibiotics; control group) and a KRT group (control treatment plus KRT). The test drugs were administered for 12 weeks to patients (15 to 64 years, outpatient) with inflammatory acne on their face, and the amount of acne at 2, 4, 8, and 12 weeks was measured. Sixty-four patients were enrolled; 29 patients in each group were included in the analysis. Twenty-eight patients in the control group and 24 pat...
Source: Dermatology Research and Practice - August 4, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Magnetic Resonance Imaging Evaluation in Patients with Linear Morphea Treated with Methotrexate and High-Dose Corticosteroid.
Conclusion: MRI could be a promising tool for the assessment of musculoskeletal and dermal involvement and also monitoring treatment response in patients with morphea. PMID: 30057597 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - August 4, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Scabies Outbreak Investigation and Risk Factors in East Badewacho District, Southern Ethiopia: Unmatched Case Control Study.
Conclusion: Outbreak of scabies occurred in East Badewacho District. Age less than 15 years, family size greater than five members, sleeping with others, and home being affected by flooding are the risk factors. Providing risk factors related health education on prevention and controls especially, at community level and schools, is recommended. PMID: 30046302 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - July 27, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Factors Influencing Patient Decisions Regarding Treatments for Skin Growths: A Cross-Sectional Study.
Authors: Li DG, Xia FD, Rana J, Young GJ, Alizadeh F, Joyce C, Das S, Mostaghimi A Abstract Variations in treatment modalities for skin growths contribute substantially to overall healthcare spending within dermatology. However, little is known regarding factors impacting patient decision-making when choosing a treatment modality. In this survey-based, cross-sectional study (n = 375, 81.9% response rate), we asked patients to rate the importance of different treatment parameters for a nonfacial skin growth, further classified into five domains: efficacy, appearance, financial impact, visit duration, and productivit...
Source: Dermatology Research and Practice - July 20, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Dietary Habits in Patients with Chronic Spontaneous Urticaria: Evaluation of Food as Trigger of Symptoms Exacerbation.
Conclusion: Despite the high frequency of self-report by patients, foods are uncommon triggers of CSU. Nevertheless, food challenge tests have to be offered early during medical evaluation to avoid unnecessary restrictions. PMID: 30018635 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - July 20, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

The Antibacterial Effect In Vitro of Honey Derived from Various Danish Flora.
Authors: Matzen RD, Zinck Leth-Espensen J, Jansson T, Nielsen DS, Lund MN, Matzen S Abstract The mechanism behind the biologic actions of honey as a wound remedy has been intensively studied; however, there is no published data regarding any antibacterial effect of honey derived from Danish flora. We surveyed 11 honeys of various Danish floral sources for their antibacterial activity and compared them to a culinary processed commercial honey (Jakobsens) and a raw and a medical grade Manuka (Leptospermum scoparium) honey using the agar-well diffusion method. We tested the effect on three gram-positive bacteria (two ...
Source: Dermatology Research and Practice - July 20, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Is Oral Omega-3 Effective in Reducing Mucocutaneous Side Effects of Isotretinoin in Patients with Acne Vulgaris?
Conclusion. Administration of oral omega-3 in acne patients who are receiving isotretinoin decreases the mucocutaneous side effects of isotretinoin. This trial is registered with  IRCT201306238241N2. PMID: 30002675 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - July 15, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Effectiveness of Traditional Healers in Program to Control Leprosy in Nagan Raya District in Aceh.
Authors: Alamsyah T, Usman S, Yusuf M, Elvin SD Abstract Aceh Province had the highest rate of leprosy in Indonesia; in 2014, 436 new Multibacillary cases were reported. Nagan Raya was the District in Aceh with the highest number of cases; new cases in 2015 comprised 26 with Paucibacillary (PB) and 21 with Multibacillary (MB) with a total of 4.26% with Grade II disability. The phenomena of handling and treatment by the people in Nagan Raya involve treatment by traditional healers, "Tabib", to treat the leprosy, with treatments known as Peundang locally. The purpose of this study was to find out and to tak...
Source: Dermatology Research and Practice - July 8, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Skin Cancer Knowledge, Attitudes, and Practices among Chinese Population: A Narrative Review.
Authors: Stephens PM, Martin B, Ghafari G, Luong J, Nahar VK, Pham L, Luo J, Savoy M, Sharma M Abstract Skin cancers are becoming a substantial public health problem in China. Fair skin and increased exposure to ultraviolet B (UVB) rays from the sun are among the most substantial risk factors for skin cancer development, thus making the Chinese people vulnerable to this group of diseases. The purpose of this article is to present a narrative review of the knowledge, attitudes, and practices (KAP) related to skin cancers within the Chinese population. A systematic electronic search of MEDLINE (PubMed), CINAHL, Scien...
Source: Dermatology Research and Practice - July 6, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Erratum to "From Localized Scleroderma to Systemic Sclerosis: Coexistence or Possible Evolution".
Erratum to "From Localized Scleroderma to Systemic Sclerosis: Coexistence or Possible Evolution". Dermatol Res Pract. 2018;2018:6984282 Authors: Giuggioli D, Colaci M, Cocchiara E, Spinella A, Lumetti F, Ferri C Abstract [This corrects the article DOI: 10.1155/2018/1284687.]. PMID: 29973952 [PubMed - in process] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - July 6, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Hidradenitis Suppurativa in Kuala Lumpur, Malaysia: A 7-Year Retrospective Review.
Conclusions: A prompt recognition of HS is imperative, to screen for comorbidities and to initiate early treatment to reduce physical and psychological complications. PMID: 29951091 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - June 30, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Comparison of the Morphological and Physical Properties of Different Absorbent Wound Dressings.
This study evaluated and compared the morphological and physical properties of six different commercially absorbent wound dressings in Thailand: two hydrocolloids, two alginates, and two foams. These wound dressings are available in a variety of components and structures, some of which have a multilayer structure. The results showed that the calcium sodium alginate dressings had better absorption properties than the calcium alginate dressings, hydrocolloid dressings, hydrocolloid with foam layer dressings, foam with polyurethane film layer dressings, and foam with hydrogel and polyurethane film layer dressings. Furthermore...
Source: Dermatology Research and Practice - June 30, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Evaluation of Lipid Profile in Patients with Cherry Angioma: A Case-Control Study in Guilan, Iran.
This study has been designed to compare frequency of dyslipidemia in subjects with and without cutaneous cherry angioma. Methods: In this case-control study, 122 cases with cherry angioma and 122 control subjects without cherry angioma were enrolled. Demographic characteristics, number of the cherry angioma lesions, and serum lipid profile were collected for all subjects. The data was analyzed using SPSS 18 software. Results: Mean levels of the total cholesterol, triglyceride, low-density lipoprotein, and high-density lipoprotein were higher in patients with cherry angioma compared to control subjects in which diff...
Source: Dermatology Research and Practice - June 6, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Clinical Features and Treatment Outcomes among Children with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A 20-Year Study in a Tertiary Referral Hospital.
Conclusions: SJS/TEN are not common but are serious diseases which lead to significant morbidities in children. Early withdrawal of suspicious causes and meticulous supportive care are very important. This study found that the systemic therapy was not superior to supportive care because the treatment outcomes for both groups were comparable. PMID: 29853855 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - June 3, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Determination of Spearman Correlation Coefficient (r) to Evaluate the Linear Association of Dermal Collagen and Elastic Fibers in the Perspectives of Skin Injury.
Authors: Kumar N, Kumar P, Badagabettu SN, Lewis MG, Adiga M, Padur AA Abstract Background: Difference in scar formation at different sites, in different directions at the same site, but with changes in the elasticity of skin with age, sex, and race or in some pathological conditions, is well known to clinicians. The inappropriate collagen syntheses and delayed or lack of epithelialization are known to induce scar formation with negligible elasticity at the site of damage. Changes in the elasticity of scars may be due to an unequal distribution of dermal collagen (C) and elastic (E) fibers. Materials and Method...
Source: Dermatology Research and Practice - June 3, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Epidemiology and Clinical Features of Adult Patients with Psoriasis in Malaysia: 10-Year Review from the Malaysian Psoriasis Registry (2007-2016).
Authors: Mohd Affandi A, Khan I, Ngah Saaya N Abstract Background: Psoriasis is a chronic inflammatory skin disease affecting 2-3% of the general population. Aim: To evaluate the epidemiology and clinical characteristics of patients with psoriasis who seek treatment in outpatient dermatology clinics throughout hospitals in Malaysia. Materials and Methods: Data were obtained from the Malaysian Psoriasis Registry (MPR). All patients (aged 18 and above) who were notified to the registry from July 2017 to December 2017 were included in this study. Results: Among 15,794 patients, Malays were the most common ...
Source: Dermatology Research and Practice - June 2, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Impetigo Herpetiformis: Review of Pathogenesis, Complication, and Treatment.
Authors: Namazi N, Dadkhahfar S Abstract Impetigo herpetiformis (IH) is among rare dermatosis of pregnancy, which is currently considered as a form of generalized pustular psoriasis. It is diagnosed by characteristic lesions of erythematous patches and grouped pustules mostly in the third trimester of pregnancy and may have systemic associations. A variety of complications have been reported in the course of IH. Treatment of IH can be quite challenging, and a number of treatment options have been reported to be effective for the management. PMID: 29849579 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - June 2, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Career Choices and Career Progression of Junior Doctors in Dermatology: Surveys of UK Medical Graduates.
Conclusion: Dermatology is popular among female UK graduates. Most dermatologists made their career decision late but decisively. PMID: 29785180 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - May 24, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Potential Use of Essential Oil Isolated from Cleistocalyx operculatus Leaves as a Topical Dermatological Agent for Treatment of Burn Wound.
In this study, we investigated the potential use of Cleistocalyx operculatus essential oil to treat the burn wound. We identified a total of 13 bioactive compounds of essential oil, several of which exhibited the anti-inflammatory and antimicrobial activities. Furthermore, the essential oil showed the antibacterial effect against S. aureus but not with P. aeruginosa. The supportive effect of essential oil on burn wound healing process also has been proven. Among three groups of mice, wound contraction rate of essential oil treated group (100%) was significantly higher than tamanu oil treated (79%) and control mice (71%) af...
Source: Dermatology Research and Practice - April 27, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

From Localized Scleroderma to Systemic Sclerosis: Coexistence or Possible Evolution.
Conclusions: LoS and SSc are two distinct clinical entities that may coexist. Moreover, as anecdotally reported in pediatric populations, we suggested the possible development of SSc in adult patients with LoS, particularly in presence of Raynaud's phenomenon or antinuclear antibodies before the SSc onset. PMID: 29666638 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - April 20, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Onychomycosis Caused by Fusarium spp. in Dakar, Senegal: Epidemiological, Clinical, and Mycological Study.
Authors: Diongue K, Ndiaye M, Seck MC, Diallo MA, Badiane AS, Ndiaye D Abstract Fusarium spp. represent 9 to 44% of onychomycoses caused by fungi other than dermatophytes. This retrospective study describes 17 cases of Fusarium onychomycosis diagnosed at the Laboratory of Parasitology and Mycology of Le Dantec University Hospital in Dakar, Senegal, from 2014 to 2016. It included all patients received in the laboratory for suspicion of onychomycosis between January 1, 2014, and December 31, 2016. Diagnosis was based on mycological examination including direct examination and culture. Mycological analysis was conside...
Source: Dermatology Research and Practice - January 20, 2018 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Prevalence and Factors Associated with Self-Medication in Dermatology in Togo.
Conclusion: Our study confirms that self-medication practice is very common among patients with dermatologic diseases in Lomé and has identified associated factors. PMID: 29259625 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - December 21, 2017 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Clinical and Genetic Review of Hereditary Acral Reticulate Pigmentary Disorders.
This article delivers an update regarding the clinical features, detailed histopathological description, and genetic information concerning hereditary reticulate pigmentary disorders and aims to provide useful background for use by clinical dermatologists and histopathologists when approaching this group of hereditary disorders. PMID: 29201043 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - December 5, 2017 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Ischaemic Preconditioning Suppresses Necrosis of Adipocutaneous Flaps in a Diabetic Rat Model Regardless of the Manner of Preischaemia Induction.
Authors: Ottomann C, Küntscher M, Hartmann B, Antonic V Abstract Ischaemic insult in the skin flaps is a major problem in reconstructive surgery particularly in patients with diabetes mellitus. Here, we sought to investigate the effectiveness of ischaemic preconditioning (IP) on diabetic skin flaps in rat animal model. Hundred Wistar rats (90 streptozotocin treated animals and 10 nondiabetic controls) were used. Diabetes mellitus was confirmed by measuring glucose level in blood, HbA1c, and ketonuria. We used blood vessel clamping, hind limb tourniquet, and NO donors (Spermine/NO complex) to induce short-term ...
Source: Dermatology Research and Practice - December 5, 2017 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Prevalence and Clinical Profile of Drug Eruptions among Antiretroviral Therapy-Exposed HIV Infected People in Yaound é, Cameroon.
CONCLUSION: Drug eruptions seem infrequent among ART-exposed HIV infected adult Cameroonians. PMID: 28744306 [PubMed] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - July 27, 2017 Category: Dermatology Tags: Dermatol Res Pract Source Type: research

Betulin-Based Oleogel to Improve Wound Healing in Dystrophic Epidermolysis Bullosa: A Prospective Controlled Proof-of-Concept Study.
CONCLUSION: Our results indicate a potential for faster reepithelialization of wounds in patients with dystrophic EB when treated with Oleogel-S10 but larger studies are needed to confirm significance. PMID: 28611842 [PubMed - in process] (Source: Dermatology Research and Practice)
Source: Dermatology Research and Practice - June 16, 2017 Category: Dermatology Tags: Dermatol Res Pract Source Type: research