A Case with Cobalamin-C-Deficiency and Severe Heart Failure Resolved by LVAD Implantation and Subsequent Heart Transplantation
Introduction: Cobalamin c deficiency (cblC), an inborn error of vitamin B12 metabolism, is caused by mutations of the MMACHC gene. Patients exhibit multisystem involvement with as many as 50% afflicted with various structural heart defects. Severe congestive heart failure (HF) may also occur with a poorly documented clinical course. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: C. Hjalmarsson, , N. Bergh, A. Thoren, J.L. Sloane, I. Manoli, C. Venditti, G. Dellgren Source Type: research
Comment on “Serum vitamin B12 concentration is associated with improved memory in older individuals with higher adherence to the Mediterranean diet” Clinical Nutrition 2024
(Source: Clinical Nutrition)
Source: Clinical Nutrition - March 31, 2024 Category: Nutrition Authors: Clarice Beatriz Gon çalves Silva, Ingrid Thayanne Souza Alves da Silva, Tiago Lacerda Ramos, Matheus Santos de Sousa Fernandes Tags: Letter to the Editor Source Type: research
Oral Vitamin B12 Versus Intra-Nasal Vitamin B12 in Transient Neurosensory Disturbances Following Third Molar Surgery: A Prospective Cohort Study
ConclusionIntra-nasal vitamin B12 sprays were found to be conducive adjuvants to treat transient neurosensory disturbances following third molar surgery. Further studies on its routine application post-neurosensory complications are recommended. (Source: Journal of Maxillofacial and Oral Surgery)
Source: Journal of Maxillofacial and Oral Surgery - March 31, 2024 Category: ENT & OMF Source Type: research
Cancers, Vol. 16, Pages 1310: Autoimmune Atrophic Gastritis: A Clinical Review
In conclusion, atrophic autoimmune gastritis is an infrequent condition, often asymptomatic and misdiagnosed, that requires an early diagnosis for appropriate vitamin supplementation and endoscopic follow-up for the early diagnosis of NETs and gastric cancer. (Source: Cancers)
Source: Cancers - March 28, 2024 Category: Cancer & Oncology Authors: Chiara Castellana Leonardo Henry Eusebi Elton Dajti Veronica Iascone Amanda Vestito Pietro Fusaroli Lorenzo Fuccio Antonietta D ’Errico Rocco Maurizio Zagari Tags: Review Source Type: research
The Alarming Rate of Malnutrition after Single Anastomosis Sleeve Ileal Bypass. A single Centre Experience
ConclusionDespite good short-term weight loss and improvement of obesity-associated complications, SASI is accompanied by high alarming malnutrition, even in short-term follow-up. Novel MBS should be judged for their long-term effects and compared to well-tested standard operations before they are used in routine clinical practice.Graphical Abstract (Source: Obesity Surgery)
Source: Obesity Surgery - March 27, 2024 Category: Surgery Source Type: research
Recurrent venous thrombosis - an unusual first presentation of autoimmune polyendocrinopathy syndrome type 3B
S Afr Med J. 2023 Dec 31;114(1):17-21. doi: 10.7196/SAMJ.2024.v114i1.1477.ABSTRACTA 45-year-old female presented with unprovoked recurrent venous thromboembolism (VTE), in unusual sites, and pancytopenia, posing a complex diagnostic challenge. Work-up for inherited thrombophilia, antiphospholipid syndrome (APLS) and paroxysmal nocturnal haemoglobinuria were unremarkable. Investigations revealed autoimmune thyroid disease, and a mixed iron/vitamin B12 deficiency due to pernicious anaemia and resultant atrophic gastritis. Hyperhomocysteinaemia due to vitamin B12 deficiency was identified as a potential contributor to her rec...
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: N Letete D Vaz P H Malishi J J Pogieter P Rheeder Source Type: research
Vitamin B12 deficiency-induced megaloblastic anemia in a pediatric patient with autism spectrum disorder with a chronically unbalanced diet
We report the case of an 11-year-old boy with ASD who developed megaloblastic anemia due to vitamin B12 deficiency. He had a prolonged history of selective eating for more than 10 years. His nutritional status on admission was poor, and he had low weight and short stature. His food selectivity was so strong that intervention to expand diet variety was unsuccessful. A developmental-behavioral pediatrician found that the patient had visual dominance and could take some medications when suffering from a minor illness. Nutritional supplements were selected after consultation with a nutritionist. Although compulsory treatment w...
Source: International Journal of Hematology - March 25, 2024 Category: Hematology Authors: Yuri Sawada Kenichi Sakamoto Atsushi Tsukamura Chihiro Sawai Source Type: research
Recurrent venous thrombosis - an unusual first presentation of autoimmune polyendocrinopathy syndrome type 3B
S Afr Med J. 2023 Dec 31;114(1):17-21. doi: 10.7196/SAMJ.2024.v114i1.1477.ABSTRACTA 45-year-old female presented with unprovoked recurrent venous thromboembolism (VTE), in unusual sites, and pancytopenia, posing a complex diagnostic challenge. Work-up for inherited thrombophilia, antiphospholipid syndrome (APLS) and paroxysmal nocturnal haemoglobinuria were unremarkable. Investigations revealed autoimmune thyroid disease, and a mixed iron/vitamin B12 deficiency due to pernicious anaemia and resultant atrophic gastritis. Hyperhomocysteinaemia due to vitamin B12 deficiency was identified as a potential contributor to her rec...
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: N Letete D Vaz P H Malishi J J Pogieter P Rheeder Source Type: research
Vitamin B12 deficiency-induced megaloblastic anemia in a pediatric patient with autism spectrum disorder with a chronically unbalanced diet
We report the case of an 11-year-old boy with ASD who developed megaloblastic anemia due to vitamin B12 deficiency. He had a prolonged history of selective eating for more than 10 years. His nutritional status on admission was poor, and he had low weight and short stature. His food selectivity was so strong that intervention to expand diet variety was unsuccessful. A developmental-behavioral pediatrician found that the patient had visual dominance and could take some medications when suffering from a minor illness. Nutritional supplements were selected after consultation with a nutritionist. Although compulsory treatment w...
Source: International Journal of Hematology - March 25, 2024 Category: Hematology Authors: Yuri Sawada Kenichi Sakamoto Atsushi Tsukamura Chihiro Sawai Source Type: research
Recurrent venous thrombosis - an unusual first presentation of autoimmune polyendocrinopathy syndrome type 3B
S Afr Med J. 2023 Dec 31;114(1):17-21. doi: 10.7196/SAMJ.2024.v114i1.1477.ABSTRACTA 45-year-old female presented with unprovoked recurrent venous thromboembolism (VTE), in unusual sites, and pancytopenia, posing a complex diagnostic challenge. Work-up for inherited thrombophilia, antiphospholipid syndrome (APLS) and paroxysmal nocturnal haemoglobinuria were unremarkable. Investigations revealed autoimmune thyroid disease, and a mixed iron/vitamin B12 deficiency due to pernicious anaemia and resultant atrophic gastritis. Hyperhomocysteinaemia due to vitamin B12 deficiency was identified as a potential contributor to her rec...
Source: South African Medical Journal - March 25, 2024 Category: African Health Authors: N Letete D Vaz P H Malishi J J Pogieter P Rheeder Source Type: research
