An Aloe-Based Composition Constituting Polysaccharides and Polyphenols Protected Mice against D-Galactose-Induced Immunosenescence
J Immunol Res. 2024 Mar 14;2024:9307906. doi: 10.1155/2024/9307906. eCollection 2024.ABSTRACTA decline in immune response, exhibited in the form of immunosenescence and inflammaging, is an age-associated disturbance of the immune system known to predispose the elderly to a greater susceptibility to infection and poor vaccine response. Polysaccharides and polyphenols from botanicals are known for their immune modulation effects. Here we evaluated a standardized mushroom-based composition, UP360, from Aloe barbadensis, Poria cocos, and Rosmarinus officinalis, as a natural nutritional supplement for a balanced immune response...
Source: Journal of Immunology Research - March 22, 2024 Category: Allergy & Immunology Authors: Mesfin Yimam Teresa Horm Alexandria O'Neal Ping Jiao Mei Hong Qi Jia Source Type: research

A systematic review and meta-analysis on the efficacy of vaccination against colibacillosis in broiler production
by Surya Paudel, Ilias Apostolakos, Ronald Vougat Ngom, Giuditta Tilli, Helena C. de Carvalho Ferreira, Alessandra Piccirillo Colibacillosis, a disease caused byEscherichia coli in broiler chickens has serious implications on food safety, security, and economic sustainability. Antibiotics are required for treating the disease, while vaccination and biosecurity are used for its prevention. This systematic review and meta-analysis, conducted under the COST Action CA18217 —European Network for Optimization of Veterinary Antimicrobial Treatment (ENOVAT), aimed to assess the efficacy ofE.coli vaccination in broiler productio...
Source: PLoS One - March 22, 2024 Category: Biomedical Science Authors: Surya Paudel Source Type: research

Genomic characterization of equine influenza A subtype H3N8 viruses by long read sequencing and functional analyses of the PB1-F2 virulence factor of A/equine/Paris/1/2018
This study assesses the potential of long-read nanopore sequencing for fast and precise sequencing of circulating equine influenza viruses. Therefore, two French Florida Clade 1 strains, including the one circulating in winter 2018 –2019 exhibiting more pronounced pathogenicity than usual, as well as the two currently OIE-recommended vaccine strains, were sequenced. Our results demonstrated the reliability of this sequencing method in generating accurate sequences. Sequence analysis of HA revealed a subtle antigenic drift in the French EIV strains, with specific substitutions, such as T163I in A/equine/Paris/1/2018 and t...
Source: Veterinary Research - March 22, 2024 Category: Veterinary Research Source Type: research

The Use of Therapy Dogs in the Pediatric COVID-19 Vaccination at the University of Puerto Rico Medical Sciences Campus
We report the experiences at a COVID-19 vaccination center after authorizing children's vaccines. When the Pfizer-BioNTech vaccine for children aged 5 to 11 years was authorized for emergency use, we adapted the center's space to receive children, adding cartoon posters and balloons and using children's adhesive bandages, among others. Located at a Campus with six health professional schools, medical students dressed as storybook or movie characters. Children were asked to make drawings during the post vaccination observation period. We incorporated therapy dogs as part of our strategy for a child-friendly center during va...
Source: Puerto Rico Health Sciences Journal - March 21, 2024 Category: International Medicine & Public Health Authors: Carmen D Zorrilla Humberto M Guiot Wanda T Maldonado-D ávila Francico J Jim énez-Ramírez Luz V Camacho Suane S ánchez Barbara Segarra Leyra Figueroa Source Type: research