NIH FDA COVID-19 SIG Lecture Series- Professor Wendy Barclay
Dr. Barclay joined Imperial College in May 2007, moving with her research group from the University of Reading where she had previously been based since 1995. She had graduated in Natural Sciences from Cambridge University and had undertaken my PhD at the Common Cold Unit, Salisbury under the joint supervision of Dr David Tyrrell and Dr Fred Brown, studying the human immune response to rhinovirus. Dr. Barclay acquired molecular virology skills as a postdoctoral fellow first in the laboratories of Professor Jeff Almond at Reading and then working with Dr Peter Palese at the Mount Sinai School of Medicine, New York.Dr. Barcl...
Source: Videocast - All Events - December 4, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Influenza Pathogenesis and Therapeutics in Vulnerable Populations
Established in 1950 in honor of former NIH Director Rolla E. Dyer, M.D., a noted authority on infectious diseases, this lectureship, now part of the Wednesday Afternoon Lecture Series, features internationally renowned researchers who have contributed substantially to medical as well as biological knowledge of infectious diseases. The Dyer Lecture is the oldest continuous lecture series at the NIH. Stacey Schultz-Cherry, PhD, is a Full Member and Professor in the Department of Infectious Diseases at St Jude Children ’ s Research Hospital in Memphis, TN as well as Senior Associate Dean for the St Jude Graduate School of...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Modeling Vaccine Responses and Tumor Immunity Using Lymph Nodes and Microfluidics
Predicting the response of the immune system to a new vaccine, immunotherapy, or infection remains a grand challenge of biomedical science. Current models of immunity largely rely on in vivo animal studies that are difficult to control and analyze over time, or simple in vitro cultures that lack the spatial organization and cell-cell interactions of the body. Here, I will share our laboratory ’ s development of technology to model immunity outside the body. By combining intact, live cultures of ex vivo lymph node tissue with microfluidic devices, we can test the impact of localized drug delivery or the effect of cocul...
Source: Videocast - All Events - January 13, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

Mammalian DNases and their role in the tug of war between Staphylococcus aureus and the host
Immunology Interest Group Victor J. Torres is a microbiologist investigating how multidrug-resistant bacteria cause disease and identifying new therapies to fight and prevent infection. Torres uses a diverse range of techniques spanning genetics, molecular biology, immunology, and bioinformatics to study the bacteria Staphylococcus aureus (S. aureus). S. aureus causes a wide range of diseases, from mild skin infections to life-threatening blood infections. Highly virulent and, in some instances, resistant to antibiotics (known as methicillin-resistant S. aureus, or MRSA), S. aureus is responsible for millions of illnesses ...
Source: Videocast - All Events - January 9, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video

NIH-FDA Immunology Interest Group 1.18.23
Victor J. Torres is a microbiologist investigating how multidrug-resistant bacteria cause disease and identifying new therapies to fight and prevent infection. Torres uses a diverse range of techniques spanning genetics, molecular biology, immunology, and bioinformatics to study the bacteria Staphylococcus aureus (S. aureus). S. aureus causes a wide range of diseases, from mild skin infections to life-threatening blood infections. Highly virulent and, in some instances, resistant to antibiotics (known as methicillin-resistant S. aureus, or MRSA), S. aureus is responsible for millions of illnesses and tens of thousands of d...
Source: Videocast - All Events - December 13, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video

How to bust up a bacterial biofilm
NIH Director's Wednesday Afternoon Lecture Series The Bakaletz laboratory ’ s research focus is attempting to understand the pathogenic mechanisms operational in the highly prevalent pediatric disease, otitis media (OM) (or middle ear infection). Specifically, we are interested in elucidating how upper respiratory tract viruses predispose the middle ear to invasion by any of the three predominant bacterial pathogens of OM (nontypeable Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae). We are also interested in understanding how bacterial biofilms contribute to the recurrence and chronicity of OM...
Source: Videocast - All Events - March 25, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Turning immunity on and off
NIH Director ’ s Wednesday Afternoon Lecture Series Dr. Hubbell uses biomaterials and protein engineering approaches to investigate topics in regenerative medicine and immunotherapeutics. In regenerative medicine, he focuses on biomaterial matrices that mimic the extracellular matrix and on growth factor - extracellular matrix interactions, working in a variety of animal models of regenerative medicine. In immunotherapeutics, he focuses on nanomaterials in vaccines that target lymphoid-resident antigen presenting cells and on protein engineering approaches to deliver antigen to the spleen and liver for inverse vaccines t...
Source: Videocast - All Events - January 17, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Molecular engineering of immunotherapeutics: from regulation in autoimmunity to immunity to cancer
NIH Director ’ s Wednesday Afternoon Lecture Series Dr. Hubbell uses biomaterials and protein engineering approaches to investigate topics in regenerative medicine and immunotherapeutics. In regenerative medicine, he focuses on biomaterial matrices that mimic the extracellular matrix and on growth factor - extracellular matrix interactions, working in a variety of animal models of regenerative medicine. In immunotherapeutics, he focuses on nanomaterials in vaccines that target lymphoid-resident antigen presenting cells and on protein engineering approaches to deliver antigen to the spleen and liver for inverse vaccines t...
Source: Videocast - All Events - January 7, 2019 Category: General Medicine Tags: Upcoming Events Source Type: video

Defining mechanisms of pathogenesis in cutaneous leishmaniasis to develop new approaches to therapy
IIG Seminar Phil Scott received his Ph.D. from the University of Pennsylvania in 1980 where he studied immunoregulatory mechanisms in experimental cutaneous leishmaniasis, and from there went to Dr. Alan Sher ’ s laboratory at NIH where he defined the role of CD4+ Th1 and Th2 cells in controlling leishmaniasis. He left NIH in 1989 to return to Penn, and rose through the ranks to become Professor of Immunology in 1995. During his time at Penn he served for 12 years as Chair of the Department of Pathobiology in the School of Veterinary Medicine, and is currently Vice Dean for Research& Academic Resources. Dr. Scott ’ s c...
Source: Videocast - All Events - November 26, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

Implementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and Beyond (Day 2)
mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and BeyondAir date: 10/17/2018 8:23:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - October 16, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and Beyond
mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and BeyondAir date: 10/17/2018 8:23:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - October 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and Beyond
mplementing Nonanimal Approaches to Human and Veterinary Vaccine Testing: Achieving Scientific and Regulatory Success for Rabies and BeyondAir date: 10/16/2018 8:00:00 AM (Source: Videocast - All Events)
Source: Videocast - All Events - October 15, 2018 Category: General Medicine Tags: Upcoming Events Source Type: video

CANCELLED - Getting to an Effective HIV Vaccine: Perspectives on Progress
DUE TO THE LIKELIHOOD OF INCLEMENT WEATHER IMPACTING THE DC METRO AREA AND THE NORTHEAST COAST, THIS LECTURE HAS BEEN POSTPONED. James C. Hill Memorial Lecture Virologist and vaccine expert Dr. Lawrence Corey will deliver the 2017 James C. Hill Memorial Lecture. His talk, titled “ Getting to an Effective HIV Vaccine: Perspectives on Progress, ” will review the state of HIV vaccine development and describe current strategies to advance the field. Since 1999, Corey has served as principal investigator of the NIAID-supported HIV Vaccine Trials Network (HVTN), which is dedicated to accelerating development of a safe and ef...
Source: Videocast - All Events - March 13, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Getting to an Effective HIV Vaccine: Perspectives on Progress
James C. Hill Memorial Lecture Virologist and vaccine expert Dr. Lawrence Corey will deliver the 2017 James C. Hill Memorial Lecture. His talk, titled “ Getting to an Effective HIV Vaccine: Perspectives on Progress, ” will review the state of HIV vaccine development and describe current strategies to advance the field. Since 1999, Corey has served as principal investigator of the NIAID-supported HIV Vaccine Trials Network (HVTN), which is dedicated to accelerating development of a safe and effective preventive HIV vaccine. The HVTN has built an international scientific collaboration of investigators in 12 countries on ...
Source: Videocast - All Events - February 27, 2017 Category: Journals (General) Tags: Upcoming Events Source Type: video

Modeling Zika virus in mice: What have we learned so far?
Immunology Interest Group Seminar Series The recent spread of Zika virus (ZIKV) and its association with increased rates of Guillain Barre and other neurological disorders as well as congenital defects that include microcephaly has created an urgent need to develop animal models to examine the pathogenesis of the disease and explore the efficacy of potential therapeutics and vaccines. Recently developed infection models for ZIKV utilize mice defective in interferon responses. This talk will describe a new model of peripheral ZIKV infection using immunocompetent neonatal C57BL/6 mice and compare its clinical progression, vi...
Source: Videocast - All Events - December 1, 2016 Category: Journals (General) Tags: Upcoming Events Source Type: video